FUSE
MCID: PLY150
MIFTS: 31

Polykaryocytosis Inducer (FUSE)

Aliases & Classifications for Polykaryocytosis Inducer

MalaCards integrated aliases for Polykaryocytosis Inducer:

Name: Polykaryocytosis Inducer 57
Fuse 57

External Ids:

OMIM 57 174750

Summaries for Polykaryocytosis Inducer

MalaCards based summary : Polykaryocytosis Inducer, also known as fuse, is related to teeth, fused and incisors, fused mandibular. An important gene associated with Polykaryocytosis Inducer is FUSE (Polykaryocytosis Promoter). The drugs Fentanyl and Midazolam have been mentioned in the context of this disorder. Affiliated tissues include bone, brain and skeletal muscle.

More information from OMIM: 174750

Related Diseases for Polykaryocytosis Inducer

Diseases related to Polykaryocytosis Inducer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 811)
# Related Disease Score Top Affiliating Genes
1 teeth, fused 12.5
2 incisors, fused mandibular 12.3
3 sirenomelia 11.9
4 ackerman syndrome 11.9
5 solitary median maxillary central incisor 11.8
6 klippel-feil syndrome 1, autosomal dominant 11.7
7 pyramidal molars-abnormal upper lip syndrome 11.7
8 klippel-feil syndrome 11.6
9 fraser syndrome 1 11.6
10 chromosome 2q35 duplication syndrome 11.5
11 craniosynostosis 11.5
12 spondyloarthropathy 1 11.5
13 fraser-like syndrome 11.5
14 rela fusion-positive ependymoma 11.5
15 apert syndrome 11.5
16 syndactyly, type v 11.5
17 horseshoe kidney 11.4
18 schizencephaly 11.4
19 synpolydactyly 11.3
20 acute promyelocytic leukemia 11.3
21 synostosis 11.3
22 anaplastic large cell lymphoma 11.3
23 myxoid liposarcoma 11.3
24 aortic valve disease 1 11.3
25 acrocallosal syndrome 11.3
26 thrombocytopenia-absent radius syndrome 11.3
27 sacral defect with anterior meningocele 11.3
28 becker nevus syndrome 11.3
29 caffey disease 11.2
30 spondylocostal dysostosis 5 11.2
31 syndactyly, type iii 11.2
32 spondylocostal dysostosis 3, autosomal recessive 11.2
33 isolated klippel-feil syndrome 11.2
34 brachydactyly, type a1 11.2
35 tarsal-carpal coalition syndrome 11.2
36 baller-gerold syndrome 11.2
37 ankyloblepharon-ectodermal defects-cleft lip/palate 11.1
38 craniosynostosis 1 11.1
39 acromesomelic dysplasia, hunter-thompson type 11.1
40 microphthalmia with limb anomalies 11.1
41 craniofacial dysmorphism, skeletal anomalies, and mental retardation syndrome 11.1
42 focal dermal hypoplasia 11.1
43 robinow syndrome 11.1
44 bladder exstrophy-epispadias-cloacal exstrophy complex 11.1
45 ring chromosome 15 11.1
46 saethre-chotzen syndrome 10.9
47 ankyloglossia with or without tooth anomalies 10.9
48 atelosteogenesis, type iii 10.9
49 blepharocheilodontic syndrome 1 10.9
50 jackson-weiss syndrome 10.9

Graphical network of the top 20 diseases related to Polykaryocytosis Inducer:



Diseases related to Polykaryocytosis Inducer

Symptoms & Phenotypes for Polykaryocytosis Inducer

Clinical features from OMIM:

174750

Drugs & Therapeutics for Polykaryocytosis Inducer

Drugs for Polykaryocytosis Inducer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 61)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
2
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
3
Calcium Approved, Nutraceutical Phase 4 7440-70-2 271
4 Cola Phase 4
5 Analgesics Phase 4
6 Anesthetics, Intravenous Phase 4
7 Neurotransmitter Agents Phase 4
8 Tranquilizing Agents Phase 4
9 Narcotics Phase 4
10 Anti-Anxiety Agents Phase 4
11 GABA Agents Phase 4
12 Adjuvants, Anesthesia Phase 4
13 Peripheral Nervous System Agents Phase 4
14 Analgesics, Opioid Phase 4
15 Hypnotics and Sedatives Phase 4
16 Central Nervous System Depressants Phase 4
17 GABA Modulators Phase 4
18 Psychotropic Drugs Phase 4
19 Anesthetics, General Phase 4
20 Calcium, Dietary Phase 4
21
Anastrozole Approved, Investigational Phase 3 120511-73-1 2187
22
Letrozole Approved, Investigational Phase 3 112809-51-5 3902
23 Estrogens Phase 3
24 Hormones Phase 3
25 Steroid Synthesis Inhibitors Phase 3
26 Antineoplastic Agents, Hormonal Phase 3
27 Hormone Antagonists Phase 3
28 Estrogen Receptor Antagonists Phase 3
29 Estrogen Antagonists Phase 3
30 Aromatase Inhibitors Phase 3
31 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3
32 English walnut Approved Phase 2
33
Acetylcholine Approved, Investigational Phase 2 51-84-3 187
34
Tacrolimus Approved, Investigational Phase 1, Phase 2 104987-11-3 445643 439492 6473866
35 Immunologic Factors Phase 2
36 Vaccines Phase 2
37 Antioxidants Phase 2
38 abobotulinumtoxinA Phase 2
39 Neuromuscular Agents Phase 2
40 Cholinergic Agents Phase 2
41 Acetylcholine Release Inhibitors Phase 2
42 incobotulinumtoxinA Phase 2
43 Botulinum Toxins Phase 2
44 Botulinum Toxins, Type A Phase 2
45 Pharmaceutical Solutions Phase 1, Phase 2
46
Metronidazole Approved 443-48-1 4173
47
tannic acid Approved 1401-55-4
48
Hydroxychloroquine Approved 118-42-3 3652
49
Benzocaine Approved, Investigational 94-09-7, 1994-09-7 2337
50 insulin

Interventional clinical trials:

(show top 50) (show all 72)
# Name Status NCT ID Phase Drugs
1 Clinical Trial to Evaluate the Efficacy and Safety of SurgiFill™ on Spinal Fusion -Comparison Between Autograft Mixed With SurgiFill™ and Autograft in Spinal Fusion- Unknown status NCT02466048 Phase 4
2 Single Center, Prospective, Open Label Post Marketing Study of EndoChoice's Fuse® Endoscopic System Performance In Routine Practice Completed NCT02439502 Phase 4
3 Fentanyl Use for Sedation in Esophagogastroduodenoscopy (FUSE): a Phase 4, Randomized, Double-blind, Placebo-controlled Trial of Fentanyl Added to Midazolam Compared to Midazolam Alone for Sedation in Routine Upper Endoscopy Completed NCT01514695 Phase 4 Midazolam;Fentanyl
4 Actifuse ABX and Local Bone Have Comparable Outcomes to Local Bone in Instrumented Multi-Level Adult Spinal Deformity Patients Terminated NCT01852747 Phase 4
5 A Randomized Controlled Trial Of The Use Of Aromatase Inhibitors, Alone And In Combination With Growth Hormone In Adolescent Boys With Idiopathic Short Stature Completed NCT01248416 Phase 3 Aromatase Inhibitor;Growth Hormone;Aromatase Inhibitor and Growth Hormone
6 A Prospective, Multi-Center Clinical Study to Assess the Saftey and Effectiveness of the Impliant TOPS System Completed NCT00405691 Phase 3
7 Adjustment of Optimal Immune System by Using Cytokine Cocktails Before Applying DC Vaccine Unknown status NCT00521287 Phase 2
8 Transurethral Autologous Myoblast Injection for Treatment of Urinary Incontinence in Children With Bladder Exstrophy Unknown status NCT02075216 Phase 1, Phase 2
9 Benefits of Walnuts for Male Reproductive Health Completed NCT01505140 Phase 2
10 Comparative Study of the Efficacy and Safety of Liposome Encapsulated Botulinum Toxin-A (Lipotoxin) Versus Normal Saline Instillation in Treatment of Patients With Refractory Overactive Bladder Syndrome Completed NCT01167257 Phase 2 Liposome encapsulated botulinum toxin A;Normal saline instillation
11 Transplantation of Myoblasts to Duchenne Muscular Dystrophy (DMD) Patients Recruiting NCT02196467 Phase 1, Phase 2
12 EVALUATION Of A NEW THERAPEUTIC STRATEGY FOR URETHRAL SPHINCTER INSUFFICIENCY BASED ON THE INTRA-URETHRAL IMPLANTATION OF AUTOLOGOUS MYOFIBERS WITH THEIR SATELLITE CELLS Completed NCT00472069 Phase 1
13 An Open Label, Phase Ib Study to Evaluate the Impact of Low Doses of Nilotinib Treatment on Safety, Tolerability and Biomarkers in Huntington's Disease Recruiting NCT03764215 Phase 1 Nilotinib 150 MG
14 Effect of a Longer Withdrawal Time or of the Use of a Wide-angle Endoscope on the Adenoma Detection Rate of Screening Colonoscopy Unknown status NCT02985944
15 A Comparative Study of the Safety and Efficacy of Face Talc Slurry and Iodopovidone for Pleurodesis Unknown status NCT00430664
16 A Study to Evaluate the Safety and Effectiveness of the TOPS System Unknown status NCT01933607
17 A Study to Evaluate the Safety and Effectiveness of the TOPS System Unknown status NCT02234154
18 Ultrasound-CT Fusion System for Interventional Radiology Procedures Unknown status NCT03226535
19 Full Spectrum vs. Standard Forward-viewing Colonoscopy With and Without Right-colon Retroflexion: a Randomized, Bicentric Back-to-back Study Completed NCT02117674
20 A 4-arm Randomized Controlled Trial of Fuse®, EndoCuff™, EndoRings™ and Standard Colonoscopy Completed NCT02345889
21 Exploratory Study of Upper and Lower Endoscopic Fuse System Completed NCT02651857
22 Evaluation of Oesogastroduodenoscopy With Vision to 245 ° (Full Spectrum Endoscopy) to View the Main Disc and Accessory Completed NCT02859883
23 Single-Center, Exploratory Study of EndoChoice's Upper&Lower Endoscopic Systems Utilizing EndoChoice's Full Spectrum Optical Technology Completed NCT02143284
24 Evaluation of the Colonoscope With Vision to 330 ° (Full Spectrum Endoscopy) in the Detection of Colorectal Adenomas Completed NCT02859870
25 Identifying Prostate Brachytherapy Seeds Using MRI Completed NCT01878058
26 Accuracy of Commercially Available Heart Rate Monitors II Completed NCT02818244
27 Post-bariatric Abdominoplasty: Skin Sensation Evaluation. Completed NCT00831610
28 Human Sperm Binding to Transgenic Mouse Eggs Completed NCT00340587
29 In Vivo Evaluation of Image Registration Techniques During Endovascular Repair Completed NCT03116880
30 Validation of a New Method of Measuring Spinal Flexibility in Axial Spondyloarthritis Using Inertial Motion (IMU) Sensors Completed NCT03159767
31 Sacroiliac Joint Fusion With iFuse Implant System (SIFI) Completed NCT01640353
32 Family Studies of the Genetics of Ankylosing Spondylitis Completed NCT00081562
33 Subjective Image Quality in Stereoscopic Image Modifications Completed NCT01624415
34 Molecular Image-directed, 3D Ultrasound-guided Biopsy of the Prostate Completed NCT02013414
35 Mindfulness and Acceptance-Based Treatments for Social Anxiety: Defusion App Completed NCT02265211
36 Genetic Determinants of Ankylosing Spondylitis Severity - Longitudinal Study Completed NCT00056719
37 Randomized Multi-Center Post Market Clinical Study to Evaluate the Safety and Performance of NextraTM for Use in Foot Surgery to Fuse the Proximal-interphalangeal- Joints Completed NCT01604070
38 The CAROLE (CArdiac Related Oncologic Late Effects) Study Completed NCT03235427
39 Lumbar Fusion or Non-operative Care for Treatment of Presumed Discogenic Pain: A Randomized Study Completed NCT02695576
40 Lumbar Spine Ultrasound of Patients With Previous Accidental Dural Puncture During Labour Epidural Completed NCT00465166
41 NaF PET/MRI Evaluation for Bone Metastases in Breast Cancer Completed NCT02103634
42 Risk Factors for Proximal Junctional Kyphosis Assessment After Spinal Instrumentation Completed NCT02881580
43 Accuracy of Commercially Available Heart Rate Monitors: A Prospective Study Completed NCT02697214
44 MRI for Non-invasive Evaluation of Brain Stress Completed NCT01898650
45 Head Circumference Growth in Children With Ehlers-Danlos Syndrome Who Develop Dysautonomia ("POTS" -- Postural Orthostatic Tachycardia Syndrome)Later in Life -- a Retrospective Analysis Completed NCT01367977
46 Supportive Tape for Arthritis of the Proximal Interphalangeal Joint: A Two Group Parallel Randomised Placebo Controlled Trial Completed NCT02220374
47 A Grading System for Laparoscopic Visualization and Predicting Factors That Affect Visualization Level During Laparoscopic Cholecystectomies: A Prospective, Single Group, Open Label Study Completed NCT02264444
48 Comparative Analysis of Transperineal Versus Transrectal Approaches for MRI-Targeted Biopsy of the Prostate for the Detection and Characterization of Prostate Cancer Recruiting NCT03366792
49 Use of Bedside Ultrasound in Emergency Department Patients With Concern for Pulmonary Embolism to Reduce CT Imaging Recruiting NCT03532165
50 Dynamics of Muscle Mitochondria in Type 2 Diabetes Recruiting NCT02977442

Search NIH Clinical Center for Polykaryocytosis Inducer

Genetic Tests for Polykaryocytosis Inducer

Anatomical Context for Polykaryocytosis Inducer

MalaCards organs/tissues related to Polykaryocytosis Inducer:

41
Bone, Brain, Skeletal Muscle, Heart, Liver, Prostate, T Cells

Publications for Polykaryocytosis Inducer

Articles related to Polykaryocytosis Inducer:

(show top 50) (show all 9114)
# Title Authors PMID Year
1
Gene assignment of a polykaryocytosis promoter (FUSE) to chromosome 10 in man. 38 8
752487 1978
2
Micropattern-based platform as a physiologically relevant model to study epithelial morphogenesis and nephrotoxicity. 38
31326655 2019
3
Robust Consensus Nonlinear Information Filter for Distributed Sensor Networks With Measurement Outliers. 38
30010605 2019
4
Fetal cortical surface atlas parcellation based on growth patterns. 38
31106942 2019
5
Mitochondrial Reactive Oxygen Species Generated at the Complex-II Matrix or Intermembrane Space Microdomain Have Distinct Effects on Redox Signaling and Stress Sensitivity in Caenorhabditis elegans. 38
30887829 2019
6
A multi-source data fusion approach to assess spatial-temporal variability and delineate homogeneous zones: A use case in a table grape vineyard in Greece. 38
31153064 2019
7
Cajal-Retzius neurons are required for the development of the human hippocampal fissure. 38
30861578 2019
8
A Hydrophobic Target: Using the Paramyxovirus Fusion Protein Transmembrane Domain To Modulate Fusion Protein Stability. 38
31217248 2019
9
Intranasal delivery of mesenchymal stem cell-derived exosomes reduces oxidative stress and markedly inhibits ethanol consumption and post-deprivation relapse drinking. 38
30239077 2019
10
Staphylococcus aureus induces autophagy in bovine mammary epithelial cells and the formation of autophagosomes facilitates intracellular replication of Staph. aureus. 38
31255277 2019
11
Retrospective Chronologic Computed Tomography Analysis of Bone Flap Fusion and Resorption After Craniotomy and Autologous Cryopreserved Cranioplasty. 38
31229749 2019
12
High ISO JPEG Image Denoising by Deep Fusion of Collaborative and Convolutional Filtering. 38
30969923 2019
13
Microdroplet Fusion Chemistry for Charge State Reduction of Synthetic Polymers via Bipolar Dual Spray with Anionic Reagents. 38
31140078 2019
14
Fusion of microplastics into the mussel byssus. 38
31158670 2019
15
Reoperation for Proximal Adjacent Segment Pathology in Posterior Cervical Fusion Constructs that Fuse to C2 vs C3. 38
30860261 2019
16
Lung Cancer-Related Mortality With Inhaled Insulin or a Comparator: Follow-Up Study of patients previously enrolled in Exubera Controlled Clinical Trials (FUSE) Final Results. 38
31331907 2019
17
Tauopathy in the periaqueductal gray, kölliker-fuse nucleus and nucleus retroambiguus is not predicted by ultrasonic vocalization in tau-P301L mice. 38
31004684 2019
18
Automatic quantification of tenosynovitis on MRI of the wrist in patients with early arthritis: a feasibility study. 38
30421014 2019
19
Efficacy of a synthetic calcium phosphate with submicron surface topography as autograft extender in lapine posterolateral spinal fusion. 38
30614621 2019
20
Integrated multiscale mathematical modeling of insulin secretion reveals the role of islet network integrity for proper oscillatory glucose-dose response. 38
31078658 2019
21
Intracranial Volume Post Cranial Expansion Surgery Using Three-Dimensional Computed Tomography Scan Imaging in Children With Craniosynostosis. 38
31403510 2019
22
Cholesterol Binding to the Transmembrane Region of a Group 2 Hemagglutinin (HA) of Influenza Virus Is Essential for Virus Replication, Affecting both Virus Assembly and HA Fusion Activity. 38
31118253 2019
23
Differential Requirements for gE, gI, and UL16 among Herpes Simplex Virus 1 Syncytial Variants Suggest Unique Modes of Dysregulating the Mechanism of Cell-to-Cell Spread. 38
31092572 2019
24
Direct Ink Writing of Poly(tetrafluoroethylene) (PTFE) with Tunable Mechanical Properties. 38
31291075 2019
25
Recombinant Fusion Streptavidin as a Scaffold for DNA Nanotetrads for Nucleic Acid Delivery and Telomerase Activity Imaging in Living Cells. 38
31269792 2019
26
Constrained Tensor Decomposition for Longitudinal Analysis of Diffusion Imaging Data. 38
31395569 2019
27
A reversible autophagy inhibitor blocks autophagosome-lysosome fusion by preventing Stx17 loading onto autophagosomes. 38
31188703 2019
28
A sum-modified-Laplacian and sparse representation based multimodal medical image fusion in Laplacian pyramid domain. 38
31410692 2019
29
A Method for High-Throughput Robotic Assembly of Three-Dimensional Vascular Tissue. 38
30638142 2019
30
Hepatitis C virus infection increases autophagosome stability by suppressing lysosomal fusion through an Arl8b-dependent mechanism. 38
31383738 2019
31
Nonwovens structure measurement based on NSST multi-focus image fusion. 38
31128534 2019
32
Chemical Interactions of Cryptic Actinomycete Metabolite 5-Alkyl-1,2,3,4-tetrahydroquinolines through Aggregate Formation. 38
31389661 2019
33
Autophagy: An evolutionarily conserved process in the maintenance of stem cells and aging. 38
31318072 2019
34
Biological characteristics of exosomes and genetically engineered exosomes for the targeted delivery of therapeutic agents. 38
31280623 2019
35
Open and cut: allosteric motion and membrane fission by dynamin superfamily proteins. 38
31365329 2019
36
Interfering with endolysosomal trafficking enhances release of bioactive exosomes. 38
31152797 2019
37
Hepatitis C Virus Entry: Protein Interactions and Fusion Determinants Governing Productive Hepatocyte Invasion. 38
31427285 2019
38
Knowledge-aware attention network for protein-protein interaction extraction. 38
31202937 2019
39
Interleukin 4 Moderately Affects Competence of Pluripotent Stem Cells for Myogenic Conversion. 38
31412558 2019
40
Fusion transcripts: Unexploited vulnerabilities in cancer? 38
31407506 2019
41
Spinal dural sac termination and internal filum terminale fusion: A Study from 80 Cadavers. 38
31376302 2019
42
Activity Recognition for IoT Devices Using Fuzzy Spatio-Temporal Features as Environmental Sensor Fusion. 38
31405220 2019
43
Drive Force and Longitudinal Dynamics Estimation in Heavy-Duty Vehicles. 38
31405235 2019
44
Excitation-inhibition balance regulates the patterning of spinal and cranial inspiratory motor outputs in rats in situ. 38
31055189 2019
45
Formulation and Characterization of Chemically Cross-linked Microbubble Clusters. 38
31310715 2019
46
Living with Two Genomes: Grafting and Its Implications for Plant Genome-to-Genome Interactions, Phenotypic Variation, and Evolution. 38
31424971 2019
47
A novel extended Pareto Optimality Consensus model for predicting essential proteins. 38
31398315 2019
48
Programmable stimuli-responsive polypeptides for biomimetic synthesis of silica nanocomposites and enzyme self-immobilization. 38
31128196 2019
49
The histomorphological structure of the male reproductive system of maize leaf weevil Tanymecus dilaticollis Gyllenhal, 1834 (Coleoptera: Curculionidae). 38
31087461 2019
50
Fuse the π-Bridge to Acceptor Moiety of Donor-π-Acceptor Conjugated Polymer: Enabling an All-Round Enhancement in Photovoltaic Parameters of Nonfullerene Organic Solar Cells. 38
31370399 2019

Variations for Polykaryocytosis Inducer

Expression for Polykaryocytosis Inducer

Search GEO for disease gene expression data for Polykaryocytosis Inducer.

Pathways for Polykaryocytosis Inducer

GO Terms for Polykaryocytosis Inducer

Sources for Polykaryocytosis Inducer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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