FUSE
MCID: PLY150
MIFTS: 31

Polykaryocytosis Inducer (FUSE)

Aliases & Classifications for Polykaryocytosis Inducer

MalaCards integrated aliases for Polykaryocytosis Inducer:

Name: Polykaryocytosis Inducer 56
Fuse 56

External Ids:

OMIM 56 174750

Summaries for Polykaryocytosis Inducer

MalaCards based summary : Polykaryocytosis Inducer, also known as fuse, is related to teeth, fused and incisors, fused mandibular. An important gene associated with Polykaryocytosis Inducer is FUSE (Polykaryocytosis Promoter). The drugs Fentanyl and Midazolam have been mentioned in the context of this disorder. Affiliated tissues include bone, brain and heart.

More information from OMIM: 174750

Related Diseases for Polykaryocytosis Inducer

Diseases related to Polykaryocytosis Inducer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 814)
# Related Disease Score Top Affiliating Genes
1 teeth, fused 12.5
2 incisors, fused mandibular 12.3
3 sirenomelia 11.9
4 solitary median maxillary central incisor 11.9
5 ackerman syndrome 11.9
6 klippel-feil syndrome 1, autosomal dominant 11.7
7 pyramidal molars-abnormal upper lip syndrome 11.7
8 klippel-feil syndrome 11.6
9 fraser syndrome 1 11.5
10 chromosome 2q35 duplication syndrome 11.5
11 craniosynostosis 11.5
12 spondyloarthropathy 1 11.5
13 fraser-like syndrome 11.5
14 rela fusion-positive ependymoma 11.5
15 apert syndrome 11.5
16 syndactyly, type v 11.5
17 horseshoe kidney 11.4
18 schizencephaly 11.4
19 synpolydactyly 11.3
20 acute promyelocytic leukemia 11.3
21 synostosis 11.3
22 anaplastic large cell lymphoma 11.3
23 myxoid liposarcoma 11.3
24 aortic valve disease 1 11.2
25 greig cephalopolysyndactyly syndrome 11.2
26 acrocallosal syndrome 11.2
27 thrombocytopenia-absent radius syndrome 11.2
28 sacral defect with anterior meningocele 11.2
29 becker nevus syndrome 11.2
30 caffey disease 11.2
31 spondylocostal dysostosis 5 11.2
32 syndactyly, type iii 11.2
33 spondylocostal dysostosis 3, autosomal recessive 11.2
34 isolated klippel-feil syndrome 11.2
35 brachydactyly, type a1 11.2
36 tarsal-carpal coalition syndrome 11.2
37 baller-gerold syndrome 11.2
38 ankyloblepharon-ectodermal defects-cleft lip/palate 11.1
39 craniosynostosis 1 11.1
40 acromesomelic dysplasia, hunter-thompson type 11.1
41 microphthalmia with limb anomalies 11.1
42 craniofacial dysmorphism, skeletal anomalies, and mental retardation syndrome 11.1
43 focal dermal hypoplasia 11.1
44 robinow syndrome 11.1
45 bladder exstrophy-epispadias-cloacal exstrophy complex 11.1
46 saethre-chotzen syndrome 10.9
47 ankyloglossia with or without tooth anomalies 10.9
48 atelosteogenesis, type iii 10.9
49 blepharocheilodontic syndrome 1 10.9
50 jackson-weiss syndrome 10.9

Graphical network of the top 20 diseases related to Polykaryocytosis Inducer:



Diseases related to Polykaryocytosis Inducer

Symptoms & Phenotypes for Polykaryocytosis Inducer

Clinical features from OMIM:

174750

Drugs & Therapeutics for Polykaryocytosis Inducer

Drugs for Polykaryocytosis Inducer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 59)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
2
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
3
Calcium Approved, Nutraceutical Phase 4 7440-70-2 271
4 Cola Phase 4
5 Anti-Anxiety Agents Phase 4
6 Narcotics Phase 4
7 Tranquilizing Agents Phase 4
8 Neurotransmitter Agents Phase 4
9 Analgesics, Opioid Phase 4
10 Anesthetics, General Phase 4
11 GABA Agents Phase 4
12 Adjuvants, Anesthesia Phase 4
13 Psychotropic Drugs Phase 4
14 Hypnotics and Sedatives Phase 4
15 Central Nervous System Depressants Phase 4
16 Anesthetics, Intravenous Phase 4
17 Analgesics Phase 4
18 GABA Modulators Phase 4
19 Calcium, Dietary Phase 4
20
Letrozole Approved, Investigational Phase 3 112809-51-5 3902
21
Anastrozole Approved, Investigational Phase 3 120511-73-1 2187
22 Estrogens Phase 3
23 Aromatase Inhibitors Phase 3
24 Hormone Antagonists Phase 3
25 Hormones Phase 3
26 Estrogen Antagonists Phase 3
27 Antineoplastic Agents, Hormonal Phase 3
28 Steroid Synthesis Inhibitors Phase 3
29 Estrogen Receptor Antagonists Phase 3
30 English walnut Approved Phase 2
31
Acetylcholine Approved, Investigational Phase 2 51-84-3 187
32
Tacrolimus Approved, Investigational Phase 1, Phase 2 104987-11-3 445643 439492 6473866
33 Vaccines Phase 2
34 Immunologic Factors Phase 2
35 Antioxidants Phase 2
36 incobotulinumtoxinA Phase 2
37 Acetylcholine Release Inhibitors Phase 2
38 abobotulinumtoxinA Phase 2
39 Botulinum Toxins Phase 2
40 Neuromuscular Agents Phase 2
41 Cholinergic Agents Phase 2
42 Botulinum Toxins, Type A Phase 2
43 Pharmaceutical Solutions Phase 1, Phase 2
44
Metronidazole Approved 443-48-1 4173
45
tannic acid Approved 1401-55-4
46
Hydroxychloroquine Approved 118-42-3 3652
47
Benzocaine Approved, Investigational 1994-09-7, 94-09-7 2337
48 insulin
49 Insulin, Globin Zinc
50 Anti-Infective Agents

Interventional clinical trials:

(show top 50) (show all 74)
# Name Status NCT ID Phase Drugs
1 Clinical Trial to Evaluate the Efficacy and Safety of SurgiFill™ on Spinal Fusion -Comparison Between Autograft Mixed With SurgiFill™ and Autograft in Spinal Fusion- Unknown status NCT02466048 Phase 4
2 Single Center, Prospective, Open Label Post Marketing Study of EndoChoice's Fuse® Endoscopic System Performance In Routine Practice Completed NCT02439502 Phase 4
3 Fentanyl Use for Sedation in Esophagogastroduodenoscopy (FUSE): a Phase 4, Randomized, Double-blind, Placebo-controlled Trial of Fentanyl Added to Midazolam Compared to Midazolam Alone for Sedation in Routine Upper Endoscopy Completed NCT01514695 Phase 4 Midazolam;Fentanyl
4 Actifuse ABX and Local Bone Have Comparable Outcomes to Local Bone in Instrumented Multi-Level Adult Spinal Deformity Patients Terminated NCT01852747 Phase 4
5 A Randomized Controlled Trial Of The Use Of Aromatase Inhibitors, Alone And In Combination With Growth Hormone In Adolescent Boys With Idiopathic Short Stature Completed NCT01248416 Phase 3 Aromatase Inhibitor;Growth Hormone;Aromatase Inhibitor and Growth Hormone
6 A Prospective, Multi-Center Clinical Study to Assess the Saftey and Effectiveness of the Impliant TOPS System Completed NCT00405691 Phase 3
7 Adjustment of Optimal Immune System by Using Cytokine Cocktails Before Applying DC Vaccine Unknown status NCT00521287 Phase 2
8 Transurethral Autologous Myoblast Injection for Treatment of Urinary Incontinence in Children With Bladder Exstrophy Unknown status NCT02075216 Phase 1, Phase 2
9 Benefits of Walnuts for Male Reproductive Health Completed NCT01505140 Phase 2
10 Comparative Study of the Efficacy and Safety of Liposome Encapsulated Botulinum Toxin-A (Lipotoxin) Versus Normal Saline Instillation in Treatment of Patients With Refractory Overactive Bladder Syndrome Completed NCT01167257 Phase 2 Liposome encapsulated botulinum toxin A;Normal saline instillation
11 Transplantation of Myoblasts to Duchenne Muscular Dystrophy (DMD) Patients Recruiting NCT02196467 Phase 1, Phase 2
12 EVALUATION Of A NEW THERAPEUTIC STRATEGY FOR URETHRAL SPHINCTER INSUFFICIENCY BASED ON THE INTRA-URETHRAL IMPLANTATION OF AUTOLOGOUS MYOFIBERS WITH THEIR SATELLITE CELLS Completed NCT00472069 Phase 1
13 An Open Label, Phase Ib Study to Evaluate the Impact of Low Doses of Nilotinib Treatment on Safety, Tolerability and Biomarkers in Huntington's Disease Recruiting NCT03764215 Phase 1 Nilotinib 150 MG
14 Effect of a Longer Withdrawal Time or of the Use of a Wide-angle Endoscope on the Adenoma Detection Rate of Screening Colonoscopy Unknown status NCT02985944
15 A Comparative Study of the Safety and Efficacy of Face Talc Slurry and Iodopovidone for Pleurodesis Unknown status NCT00430664
16 A Study to Evaluate the Safety and Effectiveness of the TOPS™ SP System Unknown status NCT03247166
17 A Study to Evaluate the Safety and Effectiveness of the TOPS System Unknown status NCT01933607
18 A Study to Evaluate the Safety and Effectiveness of the TOPS System Unknown status NCT02234154
19 Assessment of Cyclofusion Capabilities of Normal Subjects and Patients With 3D Dynamic Random-dot Stereograms Unknown status NCT03322111
20 Ultrasound-CT Fusion System for Interventional Radiology Procedures Unknown status NCT03226535
21 Neutrophils Function and Identification of Prognostic Factors in Granulomatosis With Polyangiitis (Formerly Named Wegener's Granulomatosis). Unknown status NCT01862068
22 Full Spectrum vs. Standard Forward-viewing Colonoscopy With and Without Right-colon Retroflexion: a Randomized, Bicentric Back-to-back Study Completed NCT02117674
23 A 4-arm Randomized Controlled Trial of Fuse®, EndoCuff™, EndoRings™ and Standard Colonoscopy Completed NCT02345889
24 Exploratory Study of Upper and Lower Endoscopic Fuse System Completed NCT02651857
25 Evaluation of Oesogastroduodenoscopy With Vision to 245 ° (Full Spectrum Endoscopy) to View the Main Disc and Accessory Completed NCT02859883
26 Identifying Prostate Brachytherapy Seeds Using MRI Completed NCT01878058
27 Evaluation of the Colonoscope With Vision to 330 ° (Full Spectrum Endoscopy) in the Detection of Colorectal Adenomas Completed NCT02859870
28 Single-Center, Exploratory Study of EndoChoice's Upper&Lower Endoscopic Systems Utilizing EndoChoice's Full Spectrum Optical Technology Completed NCT02143284
29 Post-bariatric Abdominoplasty: Skin Sensation Evaluation. Completed NCT00831610
30 Accuracy of Commercially Available Heart Rate Monitors II Completed NCT02818244
31 Human Sperm Binding to Transgenic Mouse Eggs Completed NCT00340587
32 In Vivo Evaluation of Image Registration Techniques During Endovascular Repair Completed NCT03116880
33 Validation of a New Method of Measuring Spinal Flexibility in Axial Spondyloarthritis Using Inertial Motion (IMU) Sensors Completed NCT03159767
34 Family Studies of the Genetics of Ankylosing Spondylitis Completed NCT00081562
35 Sacroiliac Joint Fusion With iFuse Implant System (SIFI) Completed NCT01640353
36 Subjective Image Quality in Stereoscopic Image Modifications Completed NCT01624415
37 Molecular Image-directed, 3D Ultrasound-guided Biopsy of the Prostate Completed NCT02013414
38 Mindfulness and Acceptance-Based Treatments for Social Anxiety: Defusion App Completed NCT02265211
39 Genetic Determinants of Ankylosing Spondylitis Severity - Longitudinal Study Completed NCT00056719
40 Randomized Multi-Center Post Market Clinical Study to Evaluate the Safety and Performance of NextraTM for Use in Foot Surgery to Fuse the Proximal-interphalangeal- Joints Completed NCT01604070
41 The CAROLE (CArdiac Related Oncologic Late Effects) Study Completed NCT03235427
42 Lumbar Fusion or Non-operative Care for Treatment of Presumed Discogenic Pain: A Randomized Study Completed NCT02695576
43 Risk Factors for Proximal Junctional Kyphosis Assessment After Spinal Instrumentation Completed NCT02881580
44 NaF PET/MRI Evaluation for Bone Metastases in Breast Cancer Completed NCT02103634
45 Lumbar Spine Ultrasound of Patients With Previous Accidental Dural Puncture During Labour Epidural Completed NCT00465166
46 Accuracy of Commercially Available Heart Rate Monitors: A Prospective Study Completed NCT02697214
47 MRI for Non-invasive Evaluation of Brain Stress Completed NCT01898650
48 Head Circumference Growth in Children With Ehlers-Danlos Syndrome Who Develop Dysautonomia ("POTS" -- Postural Orthostatic Tachycardia Syndrome)Later in Life -- a Retrospective Analysis Completed NCT01367977
49 Supportive Tape for Arthritis of the Proximal Interphalangeal Joint: A Two Group Parallel Randomised Placebo Controlled Trial Completed NCT02220374
50 A Grading System for Laparoscopic Visualization and Predicting Factors That Affect Visualization Level During Laparoscopic Cholecystectomies: A Prospective, Single Group, Open Label Study Completed NCT02264444

Search NIH Clinical Center for Polykaryocytosis Inducer

Genetic Tests for Polykaryocytosis Inducer

Anatomical Context for Polykaryocytosis Inducer

MalaCards organs/tissues related to Polykaryocytosis Inducer:

40
Bone, Brain, Heart, Skeletal Muscle, T Cells, Liver, Prostate

Publications for Polykaryocytosis Inducer

Articles related to Polykaryocytosis Inducer:

(show top 50) (show all 9326)
# Title Authors PMID Year
1
Gene assignment of a polykaryocytosis promoter (FUSE) to chromosome 10 in man. 61 56
752487 1978
2
Inner mitochondrial membrane compartmentalization: Dynamics across scales. 61
31931164 2020
3
Non-coding RNAs regulate autophagy process via influencing the expression of associated protein. 61
31786247 2020
4
Variability in β-catenin pulse dynamics in a stochastic cell fate decision in C. elegans. 61
32032579 2020
5
Non-Contact Sleep Stage Detection Using Canonical Correlation Analysis of Respiratory Sound. 61
30990201 2020
6
Are the facial gender and facial age variants of the composite face illusion products of a common mechanism? 61
31823299 2020
7
Partition level multiview subspace clustering. 61
31731045 2020
8
Inconsistency Calibrating Algorithms for Large Scale Piezoresistive Electronic Skin. 61
32028700 2020
9
Fabrication of bioactive inverted colloidal crystal scaffolds using expanded polystyrene beads. 61
32031058 2020
10
Ensemble classifier based on optimized extreme learning machine for motor imagery classification. 61
32015227 2020
11
Anteroposterior Translational Malalignment of Ankle Arthrodesis Alters Foot Biomechanics in Cadaveric Gait Simulation. 61
31502697 2020
12
Multi-modal neuroimaging feature selection with consistent metric constraint for diagnosis of Alzheimer's disease. 61
31841947 2020
13
C. elegans pronuclei fuse after fertilization through a novel membrane structure. 61
31834351 2020
14
Endogenous glutamatergic inputs to the Parabrachial Nucleus/ Kölliker-Fuse Complex determine respiratory rate. 61
32036030 2020
15
Membrane fusion drives pronuclear meeting in the one-cell embryo. 61
31971544 2020
16
Fusion of 3D real-time echocardiography and cine MRI using a saliency analysis. 61
31713090 2020
17
The myodural bridge complex defined as a new functional structure. 61
31563971 2020
18
Joint functional brain network atlas estimation and feature selection for neurological disorder diagnosis with application to autism. 61
31739282 2020
19
Hepatitis C Virus Entry: Protein Interactions and Fusion Determinants Governing Productive Hepatocyte Invasion. 61
31427285 2020
20
Dynamic regulation of subcellular mitochondrial position for localized metabolite levels. 61
31359061 2020
21
DNA repair by Rad52 liquid droplets. 61
32019927 2020
22
Biological characteristics of exosomes and genetically engineered exosomes for the targeted delivery of therapeutic agents. 61
31280623 2020
23
Artificial signaling in mammalian cells enabled by prokaryotic two-component system. 61
31844302 2020
24
Fusion patterns of major calvarial sutures on volume-rendered CT reconstructions. 61
32032951 2020
25
Rationale and design of the quantification of myocardial blood flow using dynamic PET/CTA-fused imagery (DEMYSTIFY) to determine physiological significance of specific coronary lesions. 61
32026327 2020
26
Myoblast Migration and Directional Persistence Affected by Syndecan-4-Mediated Tiam-1 Expression and Distribution. 61
32012800 2020
27
Endomembrane architecture and dynamics during secretion of the extracellular matrix of the unicellular charophyte, Penium margaritaceum. 61
31974570 2020
28
Model-Free Distortion Rectification Framework Bridged by Distortion Distribution Map. 61
31976891 2020
29
A Synthetic Carrier of Nucleic Acids Structured as a Neutral Phospholipid Envelope Tightly Assembled on Polyplex Surface. 61
31977157 2020
30
Improving Positioning Accuracy via Map Matching Algorithm for Visual-Inertial Odometer. 61
31963912 2020
31
Conjugation in Euplotes raikovi (Protista, Ciliophora): New Insights into Nuclear Events and Macronuclear Development from Micronucleate and Amicronucleate Cells. 61
31979289 2020
32
Multimodal feature learning and fusion on B-mode ultrasonography and sonoelastography using point-wise gated deep networks for prostate cancer diagnosis. 61
31743102 2020
33
Lipids and Lipid-Binding Proteins in Selective Autophagy. 61
31202884 2020
34
Cell-Coupled Long Short-Term Memory With L -Skip Fusion Mechanism for Mood Disorder Detection Through Elicited Audiovisual Features. 61
30892247 2020
35
FCN Based Label Correction for Multi-Atlas Guided Organ Segmentation. 61
31898145 2020
36
Hyperspectral Images Super-Resolution via Learning High-Order Coupled Tensor Ring Representation. 61
31902776 2020
37
Multimodal fusion of structural and functional brain imaging in depression using linked independent component analysis. 61
31571370 2020
38
Model Learning and Knowledge Sharing for Cooperative Multiagent Systems in Stochastic Environment. 61
31944970 2020
39
Connecting Image Denoising and High-Level Vision Tasks via Deep Learning. 61
31944972 2020
40
Explicit Filterbank Learning for Neural Image Style Transfer and Image Processing. 61
31905133 2020
41
ChiTaRS 5.0: the comprehensive database of chimeric transcripts matched with druggable fusions and 3D chromatin maps. 61
31747015 2020
42
Improving Workflow Efficiency for Mammography Using Machine Learning. 61
31153798 2020
43
Semantic Segmentation with Context Encoding and Multi-Path Decoding. 61
31940532 2020
44
Linguistic Z-number weighted averaging operators and their application to portfolio selection problem. 61
31971992 2020
45
Differential impact of two critical respiratory centres in opioid-induced respiratory depression in awake mice. 61
31589332 2020
46
Neutrophil Degranulation of Azurophil and Specific Granules. 61
31728994 2020
47
Fusion transcripts: Unexploited vulnerabilities in cancer? 61
31407506 2020
48
Collective topo-epitaxy in the self-assembly of a 3D quantum dot superlattice. 61
31611669 2020
49
Fusion of mis-registered GFP and phase contrast images with convolutional sparse representation and adaptive region energy rule. 61
31612603 2020
50
In silico prediction of potential miRNA-disease association using an integrative bioinformatics approach based on kernel fusion. 61
31747722 2020

Variations for Polykaryocytosis Inducer

Expression for Polykaryocytosis Inducer

Search GEO for disease gene expression data for Polykaryocytosis Inducer.

Pathways for Polykaryocytosis Inducer

GO Terms for Polykaryocytosis Inducer

Sources for Polykaryocytosis Inducer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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