MCID: PLY179
MIFTS: 24

Polyomavirus-Associated Nephropathy

Categories: Infectious diseases, Nephrological diseases

Aliases & Classifications for Polyomavirus-Associated Nephropathy

MalaCards integrated aliases for Polyomavirus-Associated Nephropathy:

Name: Polyomavirus-Associated Nephropathy 12 15
Polyomavirus Associated Nephropathy 12
Pvan 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0040086
UMLS 74 C1697878

Summaries for Polyomavirus-Associated Nephropathy

Disease Ontology : 12 A viral infectious disease has material basis in BK polyomavirus.

MalaCards based summary : Polyomavirus-Associated Nephropathy, also known as polyomavirus associated nephropathy, is related to kidney disease and hematopoietic stem cell transplantation. An important gene associated with Polyomavirus-Associated Nephropathy is STX18 (Syntaxin 18). The drugs Vitamin D3 and Vitamin D have been mentioned in the context of this disorder. Affiliated tissues include kidney, bone and pancreas.

Related Diseases for Polyomavirus-Associated Nephropathy

Diseases related to Polyomavirus-Associated Nephropathy via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 kidney disease 10.5
2 hematopoietic stem cell transplantation 10.0

Symptoms & Phenotypes for Polyomavirus-Associated Nephropathy

Drugs & Therapeutics for Polyomavirus-Associated Nephropathy

Drugs for Polyomavirus-Associated Nephropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 16)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Vitamin D3 Approved, Nutraceutical Phase 4 67-97-0 5280795 6221
2
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4 1406-16-2
3
Calcium Approved, Nutraceutical Phase 4 7440-70-2 271
4
Ergocalciferol Approved, Nutraceutical Phase 4 50-14-6 5280793
5 Vitamins Phase 4
6 Ergocalciferols Phase 4
7 Bone Density Conservation Agents Phase 4
8 Hormones Phase 4
9 Calcium, Dietary Phase 4
10 Epoetin alfa Phase 4 113427-24-0
11 Nutrients Phase 4
12 Vitamin D2 Phase 4
13 Trace Elements Phase 4
14 Micronutrients Phase 4
15 Hematinics Phase 4
16 Calciferol Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Correcting Anemia and Native Vitamin D Supplementation in Kidney Transplant Recipients Terminated NCT01817699 Phase 4

Search NIH Clinical Center for Polyomavirus-Associated Nephropathy

Genetic Tests for Polyomavirus-Associated Nephropathy

Anatomical Context for Polyomavirus-Associated Nephropathy

MalaCards organs/tissues related to Polyomavirus-Associated Nephropathy:

42
Kidney, Bone, Pancreas, Testes, Myeloid

Publications for Polyomavirus-Associated Nephropathy

Articles related to Polyomavirus-Associated Nephropathy:

(show top 50) (show all 63)
# Title Authors Year
1
Persistent polyomavirus-associated nephropathy in a patient with GvHD and treatment with the JAK1/2 inhibitor ruxolitinib. ( 30349038 )
2019
2
Glomerular parietal epithelial cells infection is associated with poor graft outcome in kidney transplant recipients with BK polyomavirus-associated nephropathy. ( 30649366 )
2019
3
Clinical utility of leflunomide for BK polyomavirus associated nephropathy in kidney transplant recipients: A multicenter retrospective study. ( 30730102 )
2019
4
A multicenter application of the 2018 Banff Classification for BK polyomavirus-associated nephropathy in renal transplantation. ( 30896679 )
2019
5
Predictive Value of the Combination of Peripheral Blood Lymphocyte Count and Urinary Cytology in BK Polyomavirus-associated Nephropathy. ( 31056251 )
2019
6
Aryl hydrocarbon receptor expression by macrophages and lymphocytes within infiltrates in BK polyomavirus associated nephropathy. ( 29305091 )
2018
7
BK polyomavirus microRNA expression and sequence variation in polyomavirus-associated nephropathy. ( 29518695 )
2018
8
Granulomatous inflammation in BK polyomavirus-associated nephropathy. ( 29863293 )
2018
9
Ultrasound findings of BK polyomavirus-associated nephropathy in renal transplant patients. ( 27342655 )
2017
10
Stabilization of renal function after the first year of follow-up in kidney transplant recipients treated for significant BK polyomavirus infection or BK polyomavirus-associated nephropathy. ( 28207975 )
2017
11
A delicate balance between rejection and BK polyomavirus associated nephropathy; A retrospective cohort study in renal transplant recipients. ( 28609473 )
2017
12
Simultaneous pancreas/kidney transplant recipients present with late-onset BK polyomavirus-associated nephropathy. ( 26758790 )
2016
13
Concurrent cytomegalovirus glomerulitis and BK polyomavirus-associated nephropathy in a kidney allograft biopsy. ( 26782090 )
2016
14
Predominant Tubular Interleukin-18 Expression in Polyomavirus-Associated Nephropathy. ( 26863474 )
2016
15
Intragraft Antiviral-Specific Gene Expression as a Distinctive Transcriptional Signature for Studies in Polyomavirus-Associated Nephropathy. ( 27140517 )
2016
16
Significance, cytomorphology of decoy cells in polyomavirus-associated nephropathy: Review of clinical, histopathological, and virological correlates with commentary. ( 31042494 )
2016
17
BK virus infection activates the TNFα/TNF receptor system in Polyomavirus-associated nephropathy. ( 26446017 )
2016
18
Intragraft Blood Dendritic Cell Antigen-1-Positive Myeloid Dendritic Cells Increase during BK Polyomavirus-Associated Nephropathy. ( 26701980 )
2016
19
Brincidofovir for polyomavirus-associated nephropathy after allogeneic hematopoietic stem cell transplantation. ( 25600489 )
2015
20
Polyomavirus-associated nephropathy in renal and simultaneous pancreas-kidney transplant recipients: report of three cases. ( 25579723 )
2015
21
Falsely decreased ionized calcium levels in kidney transplant recipients with polyomavirus-associated nephropathy treated with leflunomide. ( 25711674 )
2015
22
Early identification of renal transplant recipients with high risk of polyomavirus-associated nephropathy. ( 25749892 )
2015
23
Impact of HMG-CoA reductase inhibitors on the incidence of polyomavirus-associated nephropathy in renal transplant recipients with human BK polyomavirus viremia. ( 25989423 )
2015
24
Factors Influencing Graft Outcomes Following Diagnosis of Polyomavirus -Associated Nephropathy after Renal Transplantation. ( 26544696 )
2015
25
Treatment of Polyomavirus-Associated Nephropathy With the Association of Sirolimus and Leflunomide. ( 26643679 )
2015
26
Pathology of resolving polyomavirus-associated nephropathy. ( 23721552 )
2013
27
Adaptive immunity rather than viral cytopathology mediates polyomavirus-associated nephropathy in mice. ( 22420885 )
2012
28
Management of polyomavirus-associated nephropathy in renal transplant recipients. ( 22508181 )
2012
29
Analytical and clinical performance characteristics of the Simplexa BK virus quantitative PCR assay for the diagnosis of polyomavirus-associated nephropathy in renal transplant recipients using plasma and urine specimens. ( 22975084 )
2012
30
Adaptive immunity rather than viral cytopathology mediates polyomavirus-associated nephropathy in mice. ( 22994873 )
2012
31
Polyomavirus-associated nephropathy. ( 24175200 )
2012
32
Polyomavirus-associated nephropathy: a comparison of 2 different strategies for immunosuppression reduction. ( 21857366 )
2011
33
Polyomavirus associated nephropathy presenting five years after kidney transplantation. ( 21999857 )
2011
34
High incidence of malignancy in polyomavirus-associated nephropathy in renal transplant recipients. ( 20430180 )
2010
35
Polyomavirus associated nephropathy after kidney and pancreas transplantation: case report. ( 20698140 )
2010
36
Reducing immunosuppression preserves allograft function in presumptive and definitive polyomavirus-associated nephropathy. ( 21114642 )
2010
37
Evaluation of a preemptive strategy for BK polyomavirus-associated nephropathy based on prospective monitoring of BK viremia: a kidney transplantation center experience. ( 21168633 )
2010
38
The effect of low-dose cidofovir on the long-term outcome of polyomavirus-associated nephropathy in renal transplant recipients. ( 19059933 )
2009
39
Detection, distribution, and pathologic significance of BK virus strains isolated from patients with kidney transplants, with and without polyomavirus-associated nephropathy. ( 19415951 )
2009
40
Diagnostic accuracy of blood qualitative nucleic acid testing for polyomavirus-associated nephropathy in kidney recipients. ( 19444968 )
2009
41
Screening for polyomavirus associated nephropathy in renal transplantation with blood viral load measurement. ( 19559645 )
2009
42
Polyomavirus-associated nephropathy: critical issues in virological monitoring. ( 19845105 )
2009
43
A case of polyomavirus-associated nephropathy presenting late after transplantation. ( 18334968 )
2008
44
Antiviral therapy for polyomavirus-associated nephropathy after renal transplantation. ( 18658193 )
2008
45
Low-dose cidofovir for the treatment of polyomavirus-associated nephropathy: two case reports and review of the literature. ( 19195325 )
2008
46
Polyomavirus-associated nephropathy risk in kidney transplants: the influence of recipient age and donor gender. ( 17410099 )
2007
47
Polyomavirus polymerase chain reaction as a surrogate marker of polyomavirus-associated nephropathy. ( 17700158 )
2007
48
BK virus regulatory region sequence deletions in a case of human polyomavirus associated nephropathy (PVAN) after kidney transplantation. ( 16202649 )
2006
49
Retransplantation after polyomavirus-associated nephropathy: just do it? ( 16433749 )
2006
50
A mouse model for polyomavirus-associated nephropathy of kidney transplants. ( 16611327 )
2006

Variations for Polyomavirus-Associated Nephropathy

Expression for Polyomavirus-Associated Nephropathy

Search GEO for disease gene expression data for Polyomavirus-Associated Nephropathy.

Pathways for Polyomavirus-Associated Nephropathy

GO Terms for Polyomavirus-Associated Nephropathy

Sources for Polyomavirus-Associated Nephropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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