MCID: PLY153
MIFTS: 20

Polyposis of Gastric Fundus Without Polyposis Coli

Categories: Endocrine diseases, Gastrointestinal diseases

Aliases & Classifications for Polyposis of Gastric Fundus Without Polyposis Coli

MalaCards integrated aliases for Polyposis of Gastric Fundus Without Polyposis Coli:

Name: Polyposis of Gastric Fundus Without Polyposis Coli 56 71
Fundic Gland Polyposis 56

Characteristics:

OMIM:

56
Inheritance:
autosomal dominant


HPO:

31
polyposis of gastric fundus without polyposis coli:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

OMIM 56 175505
MedGen 41 C1868001
SNOMED-CT via HPO 68 263681008 78809005 87252009
UMLS 71 C1868001

Summaries for Polyposis of Gastric Fundus Without Polyposis Coli

MalaCards based summary : Polyposis of Gastric Fundus Without Polyposis Coli, also known as fundic gland polyposis, is related to gastric adenocarcinoma and proximal polyposis of the stomach and familial adenomatous polyposis. Affiliated tissues include thymus, colon and thyroid, and related phenotypes are multiple gastric polyps and abnormality of the gastric mucosa

More information from OMIM: 175505

Related Diseases for Polyposis of Gastric Fundus Without Polyposis Coli

Diseases related to Polyposis of Gastric Fundus Without Polyposis Coli via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 17)
# Related Disease Score Top Affiliating Genes
1 gastric adenocarcinoma and proximal polyposis of the stomach 11.9
2 familial adenomatous polyposis 10.6
3 colorectal cancer 10.3
4 attenuated familial adenomatous polyposis 10.3
5 neurofibromatosis, type ii 10.1
6 intussusception 10.1
7 polyposis, gastric 10.1
8 celiac disease 1 10.1
9 helicobacter pylori infection 10.1
10 gastric cancer 10.1
11 microinvasive gastric cancer 10.1
12 duodenal ulcer 10.1
13 adenocarcinoma 10.1
14 gastric adenocarcinoma 10.1
15 adenoma 10.1
16 47,xyy 10.1
17 apc-associated polyposis conditions 10.1

Graphical network of the top 20 diseases related to Polyposis of Gastric Fundus Without Polyposis Coli:



Diseases related to Polyposis of Gastric Fundus Without Polyposis Coli

Symptoms & Phenotypes for Polyposis of Gastric Fundus Without Polyposis Coli

Human phenotypes related to Polyposis of Gastric Fundus Without Polyposis Coli:

31
# Description HPO Frequency HPO Source Accession
1 multiple gastric polyps 31 HP:0004394
2 abnormality of the gastric mucosa 31 HP:0004295

Symptoms via clinical synopsis from OMIM:

56
G I:
small, sessile polyps of gastric body and fundus

Lab:
proliferation of fundic glands and cystically dilated glandular ducts
no polyposis coli

Clinical features from OMIM:

175505

Drugs & Therapeutics for Polyposis of Gastric Fundus Without Polyposis Coli

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer Recruiting NCT03030404

Search NIH Clinical Center for Polyposis of Gastric Fundus Without Polyposis Coli

Genetic Tests for Polyposis of Gastric Fundus Without Polyposis Coli

Anatomical Context for Polyposis of Gastric Fundus Without Polyposis Coli

MalaCards organs/tissues related to Polyposis of Gastric Fundus Without Polyposis Coli:

40
Thymus, Colon, Thyroid

Publications for Polyposis of Gastric Fundus Without Polyposis Coli

Articles related to Polyposis of Gastric Fundus Without Polyposis Coli:

(show top 50) (show all 68)
# Title Authors PMID Year
1
Gastric lesions in familial adenomatosis coli: their incidence and histologic analysis. 61 56
26633 1978
2
The histopathology of fundic gland polyps of the stomach. 56
3020962 1986
3
Gastric lesion of familial polyposis coli. 56
4852134 1974
4
Genetic alteration of colorectal adenoma-carcinoma sequence among gastric adenocarcinoma and dysplastic lesions in a patient with attenuated familial adenomatous polyposis. 61
32543103 2020
5
Multifocal Intramucosal Gastric Adenocarcinoma Arising in Fundic Gland Polyposis Due to Gastric Adenocarcinoma and Proximal Polyposis of the Stomach. 61
32453049 2020
6
Different phenotypes of gastric fundic gland polyposis and cancer in patients with familial adenomatous polyposis depending on Helicobacter pylori infection. 61
31529234 2019
7
Gastric Intussusception Secondary to Fundic Gland Polyposis. 61
30284202 2019
8
Gastric cancer and paraneoplastic dermatomyositis as complications of an unrecognized juvenile polyposis syndrome. 61
30873576 2019
9
First report of an Asian family with gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS) revealed with the germline mutation of the APC exon 1B promoter region. 61
29968043 2018
10
An Alpha Fetoprotein Producing Gastric Tumor with Yolk Sac, Hepatoid and Papillary Adenocarcinoma Components. 61
29207718 2017
11
ALK-positive gastric inflammatory myofibroblastic tumor in an adult with familial adenomatous polyposis and diffuse fundic polyposis. 61
28923119 2017
12
Gastric cancer in FAP: a concerning rise in incidence. 61
28185118 2017
13
Clinical outcomes of gastric polyps and neoplasms in patients with familial adenomatous polyposis. 61
28271094 2017
14
Fundic Gland Polyposis Associated with Proton-Pump Inhibitor Use. 61
30755947 2017
15
Proton pump inhibitor-induced fundic gland polyposis. 61
28049287 2017
16
The first European family with gastric adenocarcinoma and proximal polyposis of the stomach: case report and review of the literature. 61
27343414 2016
17
Resolution of Fundic Gland Polyposis following Laparoscopic Magnetic Sphincter Augmentation and Subsequent Cessation of Proton Pump Inhibitors. 61
26600954 2015
18
Morules in fundic gland polyposis: a case report. 61
24695818 2014
19
Diagnosis of Helicobacter pylori infection in gastric mucosa by endoscopic features: a multicenter prospective study. 61
23369058 2013
20
Hereditary gastric cancer. 61
23052347 2012
21
[Hepatocellular adenocarcinoma with fundic gland polyposis in adolescents associated with ileal J -pouch anal anastomosis for familial adenomatous polyposis]. 61
23268029 2012
22
Familial fundic gland polyposis with gastric cancer. 61
22027476 2012
23
Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS): a new autosomal dominant syndrome. 61
21813476 2012
24
[Massive fundic gland polyposis caused by chronic proton pump inhibitor therapy]. 61
22348851 2012
25
[A family with attenuated familial adenomatous polyposis identified because of fundic gland polyposis]. 61
21646762 2011
26
Familial adenomatous polyposis in children and adolescents. 61
20808249 2010
27
Impact of group IVA cytosolic phospholipase A2 gene polymorphisms on phenotypic features of patients with familial adenomatous polyposis. 61
19795129 2010
28
Massive fundic gland polyposis in a patient receiving protracted proton-pump inhibitor medication. 61
20150645 2010
29
Proton pump inhibitors and an emerging epidemic of gastric fundic gland polyposis. 61
18322941 2008
30
[Sporadic fundic gland polyposis--a case study]. 61
17953893 2007
31
Impact of Phospholipase A2 group IIa gene polymorphism on phenotypic features of patients with familial adenomatous polyposis. 61
17164967 2007
32
Singapore familial adenomatous polyposis (FAP) patients with classical adenomatous polyposis but undetectable APC mutations have accelerated cancer progression. 61
17026565 2006
33
High-grade dysplasia associated with fundic gland polyposis in a familial adenomatous polyposis patient, with special reference to APC mutation profiles. 61
15494708 2004
34
Multicenter experience with upper gastrointestinal polyps in pediatric patients with familial adenomatous polyposis. 61
15089902 2004
35
Familial adenomatous polyposis patients without an identified APC germline mutation have a severe phenotype. 61
14724162 2004
36
Fundic gland polyposis: two clinical settings for only one type of polyps. 61
12952513 2003
37
Impact of Helicobacter pylori infection and mucosal atrophy on gastric lesions in patients with familial adenomatous polyposis. 61
12235068 2002
38
Sporadic fundic gland polyposis: a clinical, histological, and molecular analysis. 61
12118109 2002
39
Progressive duodenal adenomatosis in a familial adenomatous polyposis pedigree with APC mutation at codon 1556. 61
11852337 2002
40
[Frequency of duodenal adenomas in patients with familial adenomatous polyposis]. 61
11572176 2001
41
Fundic gland polyposis with high-grade dysplasia in a child with attenuated familial adenomatous polyposis and familial gastric cancer. 61
11321399 2001
42
Attenuated familial adenomatous polyposis associated with advanced rectal cancer in a 16-year-old boy: report of a case. 61
11766074 2001
43
Fundic gland polyps in familial adenomatous polyposis: neoplasms with frequent somatic adenomatous polyposis coli gene alterations. 61
10980114 2000
44
Gastric adenocarcinoma associated with fundic gland polyps in a patient with attenuated familial adenomatous polyposis. 61
10445562 1999
45
Dysplastic changes in gastric fundic gland polyps of patients with familial adenomatous polyposis. 61
10379478 1999
46
APC-Associated Polyposis Conditions 61
20301519 1998
47
Gastric acne: omeprazole-induced fundic gland polyposis. 61
9469194 1998
48
Desmoid tumors in familial adenomatous polyposis/Gardner's syndrome. 61
9412915 1997
49
The clinical correlates of a 3' truncating mutation (codons 1982-1983) in the adenomatous polyposis coli gene. 61
9207294 1997
50
Thyroid neoplasia and familial adenomatous polyposis/Gardner's syndrome. 61
9085167 1997

Variations for Polyposis of Gastric Fundus Without Polyposis Coli

Expression for Polyposis of Gastric Fundus Without Polyposis Coli

Search GEO for disease gene expression data for Polyposis of Gastric Fundus Without Polyposis Coli.

Pathways for Polyposis of Gastric Fundus Without Polyposis Coli

GO Terms for Polyposis of Gastric Fundus Without Polyposis Coli

Sources for Polyposis of Gastric Fundus Without Polyposis Coli

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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