MCID: PNT001
MIFTS: 28

Pontiac Fever

Categories: Infectious diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Pontiac Fever

MalaCards integrated aliases for Pontiac Fever:

Name: Pontiac Fever 12 59 3 15 73

Characteristics:

Orphanet epidemiological data:

59
pontiac fever
Inheritance: Not applicable; Age of onset: All ages;

Classifications:

Orphanet: 59  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:0050150
Orphanet 59 ORPHA99748
UMLS via Orphanet 74 C0343528
ICD10 via Orphanet 34 A48.2
UMLS 73 C0343528

Summaries for Pontiac Fever

CDC : 3 Legionnaires’ (LEE-juh-nares) disease is a serious type of pneumonia (lung infection) caused by Legionella (LEE-juh-nell-a) bacteria. Legionella can also cause a milder illness called Pontiac fever. People can get sick when they breathe in mist or accidently swallow water into the lungs containing Legionella. Most people exposed to Legionella do not get sick. However, people 50 years or older, current or former smokers, and people with a weakened immune system or chronic disease are at increased risk.

MalaCards based summary : Pontiac Fever is related to legionellosis and legionnaires' disease. An important gene associated with Pontiac Fever is CSRP1 (Cysteine And Glycine Rich Protein 1). Affiliated tissues include lung and testes, and related phenotypes are fever and fatigue

Disease Ontology : 12 A legionellosis that involves a milder respiratory illness without pneumonia. Symptoms include fever, headache and muscle aches which last for 2 to 5 days.

Wikipedia : 76 Pontiac fever is an acute, nonfatal respiratory disease caused by various species of Gram-negative... more...

Related Diseases for Pontiac Fever

Diseases related to Pontiac Fever via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 legionellosis 12.1
2 legionnaires' disease 11.6
3 legionnaire disease 10.6
4 pneumonia 10.1
5 acute disseminated encephalomyelitis 10.1

Graphical network of the top 20 diseases related to Pontiac Fever:



Diseases related to Pontiac Fever

Symptoms & Phenotypes for Pontiac Fever

Human phenotypes related to Pontiac Fever:

59 32
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 fever 59 32 hallmark (90%) Very frequent (99-80%) HP:0001945
2 fatigue 59 32 hallmark (90%) Very frequent (99-80%) HP:0012378
3 myalgia 59 32 hallmark (90%) Very frequent (99-80%) HP:0003326
4 cough 59 32 frequent (33%) Frequent (79-30%) HP:0012735
5 headache 59 32 frequent (33%) Frequent (79-30%) HP:0002315

GenomeRNAi Phenotypes related to Pontiac Fever according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 G0/1 arrest GR00098-A-2 8.8 SDCBP SGTA TRIM37

MGI Mouse Phenotypes related to Pontiac Fever:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 8.92 CSRP1 PHEX SGTA TRIM37

Drugs & Therapeutics for Pontiac Fever

Search Clinical Trials , NIH Clinical Center for Pontiac Fever

Genetic Tests for Pontiac Fever

Anatomical Context for Pontiac Fever

MalaCards organs/tissues related to Pontiac Fever:

41
Lung, Testes

Publications for Pontiac Fever

Articles related to Pontiac Fever:

(show all 44)
# Title Authors Year
1
Outbreaks of Legionnaires' Disease and Pontiac Fever 2006-2017. ( 29744757 )
2018
2
Legionella feeleii: pneumonia or Pontiac fever? Bacterial virulence traits and host immune response. ( 30386929 )
2018
3
Comparative analysis of virulence traits between a Legionella feeleii strain implicated in Pontiac fever and a strain that caused Legionnaires' disease. ( 26386398 )
2015
4
Large outbreak of Legionnaires' disease and Pontiac fever at a military base. ( 25267405 )
2014
5
Pontiac fever among retirement home nurses associated with airborne legionella. ( 21752493 )
2011
6
Legionnaires' disease and Pontiac fever after using a private outdoor whirlpool spa. ( 20735326 )
2010
7
A cluster of Legionnaires' disease and associated Pontiac fever morbidity in office workers, Dublin, June-July 2008. ( 20414339 )
2010
8
An outbreak of Pontiac fever due to Legionella longbeachae serogroup 2 found in potting mix in a horticultural nursery in New Zealand. ( 19781115 )
2010
9
Pontiac fever outbreak associated with a spa-pool, United Kingdom, April 2008. ( 18761912 )
2008
10
Legionella bacteria in shower aerosols increase the risk of Pontiac fever among older people in retirement homes. ( 18791050 )
2008
11
A large, travel-associated outbreak of legionellosis among hotel guests: utility of the urine antigen assay in confirming Pontiac fever. ( 17173221 )
2007
12
Urine antigen tests positive for Pontiac fever: implications for diagnosis and pathogenesis. ( 17173222 )
2007
13
Pontiac fever: an operational definition for epidemiological studies. ( 16646972 )
2006
14
An outbreak of Pontiac fever with respiratory distress among workers performing high-pressure cleaning at a sugar-beet processing plant. ( 15809913 )
2005
15
Outbreak of travel-related pontiac fever among hotel guests illustrating the need for better diagnostic tests. ( 16086890 )
2005
16
Epidemiologic investigation of a restaurant-associated outbreak of Pontiac fever. ( 14583861 )
2003
17
An outbreak of travel-associated Legionnaires disease and Pontiac fever: the need for enhanced surveillance of travel-associated legionellosis in the United States. ( 11807698 )
2002
18
A whirlpool associated outbreak of Pontiac fever at a hotel in Northern Sweden. ( 11349975 )
2001
19
Pontiac fever due to Legionella micdadei from a whirlpool spa: possible role of bacterial endotoxin. ( 11679917 )
2001
20
Pontiac fever at a sewage treatment plant in the food industry. ( 10450782 )
1999
21
An outbreak of Pontiac fever among children following use of a whirlpool. ( 9636866 )
1998
22
Acute disseminated encephalomyelitis following Pontiac fever. ( 9748676 )
1998
23
Pontiac fever: non-pneumonic form of legionellosis. ( 9932628 )
1998
24
First sporadic cases of non-pneumonic legionellosis, Pontiac fever in Japan. ( 9932644 )
1998
25
[An outbreak of Pontiac fever due to Legionella pneumophila serogroup 7. I. Clinical aspects]. ( 7616010 )
1995
26
Use of polymerase chain reaction in an epidemiologic investigation of Pontiac fever. ( 8354920 )
1993
27
Hot tub legionellosis. Legionnaires' disease and Pontiac fever after a point-source exposure to Legionella pneumophila. ( 8239853 )
1993
28
Pontiac fever in children. ( 1565543 )
1992
29
Outbreak of Pontiac fever due to Legionella anisa. ( 1973219 )
1990
30
Virulence of a Legionella anisa strain associated with Pontiac fever: an evaluation using protozoan, cell culture, and guinea pig models. ( 2117580 )
1990
31
Microbiological investigations into an outbreak of Pontiac fever due to Legionella micdadei associated with use of a whirlpool. ( 2199533 )
1990
32
Pontiac fever outbreak associated with a cooling tower. ( 3565648 )
1987
33
An outbreak of Pontiac fever related to whirlpool use, Michigan 1982. ( 3968786 )
1985
34
A 1949 outbreak of Pontiac fever-like illness in steam condenser cleaners. ( 3888124 )
1985
35
Pontiac fever associated with a whirlpool spa. ( 6391156 )
1984
36
A new Legionella species, Legionella feeleii species nova, causes Pontiac fever in an automobile plant. ( 6696354 )
1984
37
Pontiac fever, amoebae, and legionellae. ( 6109071 )
1981
38
Pontiac fever: isolation of the etiologic agent (Legionella pneumophilia) and demonstration of its mode of transmission. ( 7304569 )
1981
39
Pontiac fever and amoebae. ( 6108406 )
1980
40
Pontiac fever explained? ( 6107603 )
1980
41
Legionellosis: Legionnaires' disease; Pontiac fever. ( 6993807 )
1980
42
Nonpneumonic, short-incubation-period Legionellosis (Pontiac fever) in men who cleaned a steam turbine condenser. ( 462175 )
1979
43
Pontiac fever. An epidemic of unknown etiology in a health department: I. Clinical and epidemiologic aspects. ( 623097 )
1978
44
Hot-bath syndrome, Pontiac fever, and Legionnaires' disease. ( 73920 )
1977

Variations for Pontiac Fever

Expression for Pontiac Fever

Search GEO for disease gene expression data for Pontiac Fever.

Pathways for Pontiac Fever

GO Terms for Pontiac Fever

Molecular functions related to Pontiac Fever according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 zinc ion binding GO:0008270 8.8 CSRP1 PHEX TRIM37

Sources for Pontiac Fever

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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