MCID: PRT018
MIFTS: 50

Portal Vein Thrombosis

Categories: Cardiovascular diseases, Endocrine diseases, Gastrointestinal diseases, Blood diseases

Aliases & Classifications for Portal Vein Thrombosis

MalaCards integrated aliases for Portal Vein Thrombosis:

Name: Portal Vein Thrombosis 12 76 29 55 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:11695
ICD10 33 I81
ICD9CM 35 452
NCIt 50 C78565
SNOMED-CT 68 155455003 17920008
UMLS 73 C0155773

Summaries for Portal Vein Thrombosis

Disease Ontology : 12 A vein disease that is characterized by a blood clot that forms within the hepatic portal vein.

MalaCards based summary : Portal Vein Thrombosis is related to liver cirrhosis and hypersplenism. An important gene associated with Portal Vein Thrombosis is F2 (Coagulation Factor II, Thrombin), and among its related pathways/superpathways are Collagen chain trimerization and Response to elevated platelet cytosolic Ca2+. The drugs Benzocaine and Nadroparin have been mentioned in the context of this disorder. Affiliated tissues include liver, spleen and pancreatic islet, and related phenotypes are homeostasis/metabolism and integument

Wikipedia : 76 Portal vein thrombosis is a form of venous thrombosis affecting the hepatic portal vein, which can lead... more...

Related Diseases for Portal Vein Thrombosis

Diseases related to Portal Vein Thrombosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 263)
# Related Disease Score Top Affiliating Genes
1 liver cirrhosis 30.8 AFP F2 SERPINC1
2 hypersplenism 30.6 F2 SERPINC1
3 splenic infarction 30.4 APOH F2
4 purpura 30.1 APOH F2 SERPINC1
5 protein c deficiency 30.1 F2 F5 MTHFR SERPINC1
6 homocystinuria 30.0 F5 MTHFR SERPINC1
7 hepatic veno-occlusive disease 29.9 SERPINC1 SERPINE1
8 esophageal varix 29.7 AFP F2 SERPINC1
9 hemophilia 29.6 F2 F7
10 polycythemia vera 29.6 F5 JAK2 SELP
11 hemophilia a 29.6 F5 F7
12 eclampsia 29.5 F2 F5 MTHFR SERPINC1
13 hepatic infarction 29.5 APOH F2 MTHFR SERPINC1
14 thrombocytosis 29.3 F2 JAK2 SELP SERPINC1
15 acute myocardial infarction 29.2 SELP SERPINC1 SERPINE1
16 protein s deficiency 29.1 APOH F2 F5 MTHFR SERPINC1
17 antithrombin iii deficiency 29.0 APOH F2 F5 MTHFR SERPINC1
18 essential thrombocythemia 28.8 F2 JAK2 SELP SERPINE1
19 thrombosis 28.3 APOH F2 F5 JAK2 MTHFR SELP
20 disseminated intravascular coagulation 28.1 F2 F5 F7 SERPINC1 SERPINE1
21 thrombophilia due to thrombin defect 27.9 APOH F2 F5 MTHFR SERPINC1 SERPINE1
22 pulmonary embolism 27.9 APOH F2 F5 MTHFR SERPINC1 SERPINE1
23 antiphospholipid syndrome 27.8 APOH F2 F5 MTHFR SELP SERPINC1
24 budd-chiari syndrome 27.6 APOH F2 F5 F7 JAK2 MTHFR
25 cerebrovascular disease 26.9 F2 F5 F7 MTHFR SELP SERPINE1
26 myocardial infarction 26.4 F2 F5 F7 MTHFR SELP SERPINC1
27 thrombophilia 26.4 APOH F2 F5 F7 JAK2 MTHFR
28 pre-eclampsia 25.8 AFP APOH F2 F5 MTHFR SELP
29 stroke, ischemic 25.3 APOH F2 F5 F7 MTHFR SELP
30 primitive portal vein thrombosis 12.6
31 dehydrated hereditary stomatocytosis 1 with or without pseudohyperkalemia and/or perinatal edema 11.0
32 paracetamol poisoning 10.8 F2 F5
33 hemoglobin e disease 10.7 F2 F5
34 hepatocellular carcinoma 10.7
35 factor viii deficiency 10.7 F2 F5
36 ischemic neuropathy 10.7 F2 MTHFR
37 intestinal impaction 10.6 F2 SERPINC1
38 fournier gangrene 10.6 F2 SERPINC1
39 leech infestation 10.6 F2 SERPINC1
40 alpha-2-plasmin inhibitor deficiency 10.6 F2 SERPINC1
41 hepatitis 10.6
42 giant hemangioma 10.6 F2 SERPINC1
43 intracranial embolism 10.6 F2 SERPINC1
44 anterior spinal artery syndrome 10.6 F2 SERPINC1
45 scott syndrome 10.5 F2 F5
46 neonatal stroke 10.5 MTHFR SERPINE1
47 purpura fulminans 10.5 F2 SERPINC1
48 may-thurner syndrome 10.5 APOH F5
49 korean hemorrhagic fever 10.5 F2 SERPINC1
50 acanthamoeba keratitis 10.5 APOH F5

Comorbidity relations with Portal Vein Thrombosis via Phenotypic Disease Network (PDN):


Active Peptic Ulcer Disease Acute Vascular Insufficiency of Intestine
Hepatic Encephalopathy Portal Hypertension

Graphical network of the top 20 diseases related to Portal Vein Thrombosis:



Diseases related to Portal Vein Thrombosis

Symptoms & Phenotypes for Portal Vein Thrombosis

MGI Mouse Phenotypes related to Portal Vein Thrombosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.96 MTHFR SELP SERPINC1 SERPINE1 AFP APOH
2 integument MP:0010771 9.63 JAK2 MTHFR SELP SERPINE1 F2 F5
3 liver/biliary system MP:0005370 9.43 JAK2 SELP SERPINC1 SERPINE1 AFP F5
4 mortality/aging MP:0010768 9.32 MTHFR SELP SERPINC1 SERPINE1 AFP APOH

Drugs & Therapeutics for Portal Vein Thrombosis

Drugs for Portal Vein Thrombosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 117)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Benzocaine Approved, Investigational Phase 4,Not Applicable 1994-09-7, 94-09-7 2337
2 Nadroparin Approved, Investigational Phase 4,Not Applicable 9041-08-1
3
Warfarin Approved Phase 4,Phase 3,Not Applicable 81-81-2 6691 54678486
4
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
5
Dalteparin Approved Phase 4,Phase 3,Phase 2,Not Applicable 9005-49-6
6
Dipyridamole Approved Phase 4 58-32-2 3108
7
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 9005-49-6 772 46507594
8
Cisplatin Approved Phase 4 15663-27-1 84093 441203 2767
9
Ethiodized oil Approved, Investigational Phase 4,Not Applicable 8008-53-5
10 tannic acid Approved, Nutraceutical Phase 4,Not Applicable
11
Glucosamine Approved, Investigational, Nutraceutical Phase 4 3416-24-8 439213
12 Anticoagulants Phase 4,Phase 3,Phase 2,Not Applicable
13 Bone Density Conservation Agents Phase 4,Not Applicable
14 Calcium, Dietary Phase 4,Phase 2,Not Applicable
15 Fibrinolytic Agents Phase 4,Phase 3,Phase 2,Not Applicable
16 Liver Extracts Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
17 Vasodilator Agents Phase 4,Phase 3,Phase 2,Not Applicable
18 Antimetabolites Phase 4,Phase 3,Phase 2,Not Applicable
19 Analgesics Phase 4
20 Analgesics, Non-Narcotic Phase 4
21 Anti-Inflammatory Agents Phase 4
22 Anti-Inflammatory Agents, Non-Steroidal Phase 4
23 Antipyretics Phase 4
24 Antirheumatic Agents Phase 4
25 calcium heparin Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
26 Cyclooxygenase Inhibitors Phase 4
27 Heparin, Low-Molecular-Weight Phase 4,Phase 3,Phase 2,Not Applicable
28 Peripheral Nervous System Agents Phase 4
29 Phosphodiesterase Inhibitors Phase 4
30 Platelet Aggregation Inhibitors Phase 4,Phase 2
31 Pharmaceutical Solutions Phase 4,Phase 3
32 Glucuronyl glucosamine glycan sulfate Phase 4
33 Hypoglycemic Agents Phase 4
34 Hypolipidemic Agents Phase 4,Phase 3
35 Lipid Regulating Agents Phase 4,Phase 3
36 insulin Phase 4
37 Insulin, Globin Zinc Phase 4
38
Norfloxacin Approved Phase 3 70458-96-7 4539
39
Propranolol Approved, Investigational Phase 3,Not Applicable 525-66-6 4946
40
Simvastatin Approved Phase 3 79902-63-9 54454
41
Rivaroxaban Approved Phase 3,Not Applicable 366789-02-8
42
Enoxaparin Approved Phase 3,Phase 2,Not Applicable 9005-49-6 772
43
Sorafenib Approved, Investigational Phase 3,Phase 2 284461-73-0 216239 406563
44
Apixaban Approved Phase 3 503612-47-3 10182969
45
Serine Approved, Nutraceutical Phase 3,Not Applicable 56-45-1 5951
46 Adrenergic Agents Phase 3,Not Applicable
47 Adrenergic Antagonists Phase 3,Not Applicable
48 Adrenergic beta-Antagonists Phase 3,Not Applicable
49 Anti-Arrhythmia Agents Phase 3,Not Applicable
50 Anti-Bacterial Agents Phase 3,Not Applicable

Interventional clinical trials:

(show top 50) (show all 79)
# Name Status NCT ID Phase Drugs
1 The Effect of Anticoagulation After Endoscopic Therapy in Cirrhotic Patients With Portal Vein Thrombosis Unknown status NCT02398357 Phase 4 Nadroparin Calcium and Warfarin
2 Warfarin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy and Azygoportal Disconnection Completed NCT02247414 Phase 4 Warfarin;Dipyridamole;Aspirin;Low Molecular Weight Heparin
3 Outcome of Transarterial Chemo-embolization (TACE) in Hepatocellular Carcinoma Patients With Partial Portal Vein Thrombosis Completed NCT03007212 Phase 4
4 A Clinical Trial of the Vessel Sealing System (LigaSure) in Azygoportal Disconnection and Splenectomy in Patients With Portal Hypertension Completed NCT00965744 Phase 4
5 Intraoperative Glucose Control in Liver Transplant Completed NCT00780026 Phase 4 insulin
6 Warfarin Prevents Portal Vein Thrombosis in Liver Cirrhotic Patients With Hypersplenism After Laparoscopic Splenectomy Recruiting NCT02238444 Phase 4 Warfarin;Dipyridamole;Aspirin;Low Molecular Weight Heparin
7 The Effect of Anticoagulation in Cirrhotic Patients With Portal Vein Thrombosis:A Multicenter RCT Not yet recruiting NCT02630095 Phase 4 Nadroparin Calcium and Warfarin
8 ETOS: Minimal Hepatic Encephalopathy in Childhood and Young Adult: epidemiOlogical Study and Pilot Interventional Study Unknown status NCT01798329 Phase 3
9 Probiotics for Portal Hypertension Unknown status NCT01134692 Phase 3 Propranolol, Norfloxacin, VSL#3
10 Conservative Treatment Versus Elective Repair of Umbilical Hernia in Patients With Ascites and Liver Cirrhosis Unknown status NCT01421550 Phase 3
11 Placebo-controlled Study of NPB-06 in Patients With Portal Vein Thrombosis Completed NCT02250391 Phase 3 NPB-06;Placebo
12 Efficacy of Statin Association With Standard Treatment in Prevention of Recurrent Hemorrhage in Patient With Cirrhosis and Variceal Bleeding Completed NCT01095185 Phase 3 Simvastatin;Placebo
13 Efficacy and Safety of Rivaroxaban in the Management of Acute Non-neoplastic PVT Compensated Cirrhosis Recruiting NCT03193502 Phase 3 rivaroxaban
14 TIPS for Variceal Rebleeding in Cirrhotic Patients With Occlusive Portal Vein Thrombosis and CTPV Recruiting NCT02853526 Phase 3 Propranolol;Warfarin
15 Treatment of Splanchnic Vein Thrombosis With Rivaroxaban. A Pilot, Prospective Cohort Study Recruiting NCT02627053 Phase 3 rivaroxaban
16 Multicenter Prospective Randomized Trial of the Effect of Rivaroxaban on Survival and Development of Complications of Portal Hypertension in Patients With Cirrhosis Recruiting NCT02643212 Phase 3 Rivaroxaban;Placebo
17 Dual Hypothermic Oxygenated Perfusion of DCD Liver Grafts in Preventing Biliary Complications After Transplantation Recruiting NCT02584283 Phase 3 Glutathione
18 Xarelto Versus no Treatment for the Prevention of Recurrent Thrombosis in Patients With Chronic Portal Vein Thrombosis. Active, not recruiting NCT02555111 Phase 3 Xarelto
19 Safety and Efficacy of Bemiparin in the Prevention of Thrombotic Events in Hospitalized Cirrhotic Patients Active, not recruiting NCT02802605 Phase 3 Bemiparin
20 Apixaban or Dalteparin in Reducing Blood Clots in Patients With Cancer Related Venous Thromboembolism Active, not recruiting NCT02585713 Phase 3 Apixaban;Dalteparin
21 TIPS or Anticoagulation in Portal Vein Thrombosis Not yet recruiting NCT03422419 Phase 3 Heparin
22 Role of (LMWH) in Prevention of Thromboembolic Complication After (TACE) in Hepatocellular Carcinoma. Not yet recruiting NCT02715492 Phase 3 LMWH
23 Impact on Morbidity and Mortality of Prophylactic Dosing of Low Molecular Heparin in Child-Pugh B Cirrhotic Patients Suspended NCT02271295 Phase 3 Enoxaparine
24 Efficacy Evaluation of TheraSphere to Treat Inoperable Liver Cancer With Blockage of the Portal Vein Terminated NCT01887717 Phase 3 Sorafenib
25 Islet Transplantation Through an Indwelling Catheter in the Umbilical Vein Completed NCT02367534 Phase 1, Phase 2
26 Radioembolization With Yttrium-90 Microspheres for Intermediate or Advanced Hepatocellular Carcinoma Completed NCT00910572 Phase 2
27 Japanese Phase II Study of SB-497115-GR in Hepatitis C Virus Infected Patients Completed NCT01636778 Phase 2 SB-497115-GR
28 Sorafenib Plus Hepatic Arterial Infusion Versus Sorafenib for HCC With Major Portal Vein Tumor Thrombosis Recruiting NCT03009461 Phase 2 Sorafenib
29 Pneumatic Reversible Portal Vein Diameter Modulation After Major Hepatectomy Recruiting NCT02390713 Phase 1, Phase 2
30 Phase II Study of Concurrent Sorafenib and Intensity-modulated Radiotherapy (IMRT) for Advanced Hepatocellular Carcinoma Recruiting NCT03535259 Phase 2
31 Complement Inhibitor Eculizumab in Clinical Islet Transplantation Recruiting NCT02727608 Phase 2 Eculizumab
32 Safety, Efficacy of Eglandin® in Living Donor Liver Transplanted Patient (PROVISION) Active, not recruiting NCT02350218 Phase 2 Eglandin
33 Anticoagulation Post Laparoscopic Splenectomy Terminated NCT00769873 Phase 2 Enoxaparin
34 Safety Study of Autologous Stem Cell in Liver Cirrhosis Terminated NCT00382278 Phase 1, Phase 2
35 The Safety and Maximum Tolerated Dose of Axitinib in Combination With Radiotherapy for HCC Recruiting NCT02814461 Phase 1 Axitinib
36 Islet Allotransplantation in Type 1 Diabetes Enrolling by invitation NCT01705899 Phase 1 Human Pancreatic Islets
37 Reversible Portal Vein Embolization Before Major Hepatectomy Not yet recruiting NCT02945059 Phase 1
38 Incidence of Venous Thromboembolic Disease and Portal Vein Thrombosis After Hepatectomy. A Cohort Study. Unknown status NCT02597218
39 Pair Production PET Imaging to Detect Particle Distribution in Patients Undergoing Yttrium-90 Radioembolization Unknown status NCT02848638
40 Circulating Tumor Cell Genome in Peripheral Blood From Hepatocellular Carcinoma Patients Under Radiotherapy Unknown status NCT02066974
41 Liver Transplantation for Hilar Cholangiocarcinoma in Association With Neoadjuvant Radio- and Chemo-therapy Unknown status NCT01549795 Not Applicable Capecitabine
42 Prevalence and Predictive Factors of Portal Vein Thrombosis in Patients With Cirrhosis Completed NCT02069457
43 Efficacy and Safety of Rivaroxaban in Acute Non-neoplastic Portal Vein Thrombosis in HCV Completed NCT03201367 Not Applicable Rivaroxaban
44 TheraSpheres Treatment for Unresectable Hepatocarcinoma and Portal Vein Thrombosis Completed NCT01556282 Not Applicable
45 Portal Vein Thrombosis Relevance on Liver Cirrhosis: Italian Venous Thrombotic Events Registry Completed NCT01470547
46 Transjugular Intrahepatic Portosystemic Shunt (TIPS) for Prevention of Variceal Rebleeding in Cirrhotic Patients With Portal Vein Thrombosis Completed NCT01326949 Not Applicable
47 Proteomic Analysis of Human Hepatocellular Carcinoma Completed NCT01177631 Not Applicable
48 Rifaximin in Patients With Gastroesophageal Variceal Bleeding Completed NCT02991612 Not Applicable Rifaximin
49 HEMOCC Study. Hemostasis in Cirrhotic Children. Completed NCT03244332 Not Applicable
50 Anatomical Resection of the Liver for Hepatocellular Carcinoma: a New Ultrasound Guided Approach Completed NCT00829335

Search NIH Clinical Center for Portal Vein Thrombosis

Genetic Tests for Portal Vein Thrombosis

Genetic tests related to Portal Vein Thrombosis:

# Genetic test Affiliating Genes
1 Portal Vein Thrombosis 29

Anatomical Context for Portal Vein Thrombosis

MalaCards organs/tissues related to Portal Vein Thrombosis:

41
Liver, Spleen, Pancreatic Islet, Colon, Bone, Myeloid, Pancreas

Publications for Portal Vein Thrombosis

Articles related to Portal Vein Thrombosis:

(show top 50) (show all 743)
# Title Authors Year
1
Thrombopoietin receptor agonists and risk of portal vein thrombosis in patients with liver disease and thrombocytopenia: A meta-analysis. ( 29958825 )
2018
2
Regenerative nodular hyperplasia, portal vein thrombosis and primary myelofibrosis: An unusual triple association. ( 29368941 )
2018
3
Anticoagulation for Portal Vein Thrombosis in Liver Cirrhosis: Not Only Recanalize the PortalA Vein. ( 29351835 )
2018
4
A case of portal vein thrombosis caused by blunt abdominal trauma in a patient with low protein C activity. ( 29923164 )
2018
5
Congenital Thrombophilia in Patients With Superior Mesenteric Venous Thrombosis or Portal Vein Thrombosis. ( 29747524 )
2018
6
Portal Vein Thrombosis: Imaging the Spectrum of Disease With an Emphasis on MRI Features. ( 29792748 )
2018
7
Liver Atrophy and Regeneration in Non-Cirrhotic Portal Vein Thrombosis: Effect of Surgical Shunts. ( 29377486 )
2018
8
The use of nonselective beta blockers is a risk factor for portal vein thrombosis in cirrhotic patients. ( 29451181 )
2018
9
Portal vein thrombosis: What surgeons need to know. ( 29963409 )
2018
10
Randomized controlled trial of rivaroxaban versus warfarin in the management of acute non-neoplastic portal vein thrombosis. ( 29886103 )
2018
11
Newer Oral Anticoagulants in the Treatment of Acute Portal Vein Thrombosis in Patients with and without Cirrhosis. ( 29973997 )
2018
12
Response to Portal vein thrombosis after hepatitis C eradication with direct acting antiviral therapy. ( 29272568 )
2018
13
Portal vein thrombosis: yes or no on anticoagulation therapy. ( 29432256 )
2018
14
Phase II Study of Sorafenib Combined with Concurrent Hepatic Arterial Infusion of Oxaliplatin, 5-Fluorouracil and Leucovorin for Unresectable Hepatocellular Carcinoma with Major Portal Vein Thrombosis. ( 29327075 )
2018
15
Portal vein thrombosis after donor liver biopsy: Case report. ( 29692529 )
2018
16
Gastrointestinal: Duodenal variceal bleeding secondary to thrombophilia-related portal vein thrombosis. ( 29372608 )
2018
17
Serum ADAMTS-13 Levels as an Indicator of Portal Vein Thrombosis. ( 29849584 )
2018
18
Acute portal vein thrombosis after hepatectomy in a patient with hepatolithiasis: A case report and review of the literature. ( 29924030 )
2018
19
Treatment of portal vein thrombosis in cirrhosis: is it really needed? ( 29979322 )
2018
20
Prospective longitudinal quality of life and survival outcomes in patients with advanced infiltrative hepatocellular carcinoma and portal vein thrombosis treated with Yttrium-90 radioembolization. ( 29329568 )
2018
21
Low-molecular-weight heparin treatment for portal vein thrombosis in liver cirrhosis: Efficacy and the risk of hemorrhagic complications. ( 29407630 )
2018
22
Transient portal vein thrombosis in liver cirrhosis. ( 29871683 )
2018
23
Obesity is not associated with an increased risk of portal vein thrombosis in cirrhotic patients. ( 29910857 )
2018
24
Direct oral anticoagulants and cirrhosis: More evidence still needed for efficacy and safety in portal vein thrombosis. ( 29890295 )
2018
25
Timing of the Treatment of Portal Vein Thrombosis in Patients with Cirrhosis: A German Hepatologist's Perspective. ( 29607298 )
2018
26
The disseminated intravascular coagulation score is a novel predictor for portal vein thrombosis in cirrhotic patients with hepatitis B. ( 29178991 )
2018
27
Anticoagulation in non-malignant portal vein thrombosis is safe and improves hepatic function. ( 29916054 )
2018
28
Anticoagulation treatment of portal vein thrombosis in a patient with cirrhosis awaiting liver transplantation: A case report. ( 29952969 )
2018
29
Adult Living Donor Liver Transplantation for Patients With Portal Vein Thrombosis: A Single-center Experience. ( 29796412 )
2018
30
Portal Vein Thrombosis: A Rare Complication of Nephrotic Syndrome. ( 29962677 )
2018
31
Portal vein thrombosis in cirrhosis: diagnosis, natural history, and therapeutic challenges. ( 29720857 )
2018
32
Endoscopic ultrasound-guided fine-needle aspiration of portal vein thrombosis in patients with chronic liver disease and suspicion of hepatocellular carcinoma. ( 29420366 )
2018
33
Incidence rates and case fatality rates of portal vein thrombosis and Budd-Chiari Syndrome. ( 28180235 )
2017
34
Antithrombin III for portal vein thrombosis in patients with liver disease: A randomized, double-blind, controlled trial. ( 28666312 )
2017
35
Portal vein thrombosis after hepatitis C eradication with direct acting antiviral therapy. ( 28782876 )
2017
36
Liver Transplant in Patients with Portal Vein Thrombosis: Medical and Surgical Requirements. ( 28834305 )
2017
37
Effects of Portal Vein Thrombosis on the Outcomes of Liver Cirrhosis: A Mexican Perspective. ( 29340273 )
2017
38
Discrepant imaging findings of portal vein thrombosis with dynamic computed tomography and computed tomography during arterial portography in hepatocellular carcinoma: possible cause leading to inappropriate treatment selection. ( 28181172 )
2017
39
Liver Transplantation in Patients With Complete Portal Vein Thrombosis: Renoportal or Varicoportal Anastomosis Using Cryopreserved Vein Grafts. ( 28923632 )
2017
40
Portal vein thrombosis after laparoscopic total colectomy for colonic inertia. ( 28928915 )
2017
41
Association of Nonmalignant Portal Vein Thrombosis and Outcomes after Transjugular Intrahepatic Portosystemic Shunt in Patients with Cirrhosis. ( 28682164 )
2017
42
Transjugular Intrahepatic Portosystemic Shunt as the Treatment for Refractory Hepatic Hydrothorax with Portal Vein Thrombosis. ( 28776556 )
2017
43
Portal Vein Thrombosis After Percutaneous Liver Biopsy. ( 28780205 )
2017
44
Thromboelastometry hypercoagulable profiles and portal vein thrombosis in cirrhotic patients with hepatocellular carcinoma. ( 28109767 )
2017
45
Successful medical management of acute mesenteric ischemia due to superior mesenteric and portal vein thrombosis in a 27-year-old man with protein S deficiency: a case report. ( 29117862 )
2017
46
Serum omentin and vaspin levels in cirrhotic patients with and without portal vein thrombosis. ( 28465646 )
2017
47
Corrigendum: Portal vein thrombosis - a primer for the general physician. ( 28765412 )
2017
48
Risk prediction for portal vein thrombosis in acute pancreatitis using radial basis function. ( 28943487 )
2017
49
Call for Caution: Neonatal Portal Vein Thrombosis following Enbucrilate Embolization of Placental Chorioangioma. ( 28796996 )
2017
50
Hepatic infarction from portal vein thrombosis: A fatal consequence of acute pancreatitis. ( 28421699 )
2017

Variations for Portal Vein Thrombosis

Expression for Portal Vein Thrombosis

Search GEO for disease gene expression data for Portal Vein Thrombosis.

Pathways for Portal Vein Thrombosis

Pathways related to Portal Vein Thrombosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.39 F2 F5 F7 SERPINC1
2
Show member pathways
12.3 APOH F2 F5 F7 JAK2 SELP
3
Show member pathways
11.89 F2 F7 MTHFR SERPINE1
4
Show member pathways
11.76 F2 F5 F7 SERPINC1 SERPINE1
5 11.5 F2 F5 F7 SERPINC1 SERPINE1
6 11.08 AFP F2
7
Show member pathways
10.87 JAK2 SELP
8 10.5 F2 F7

GO Terms for Portal Vein Thrombosis

Cellular components related to Portal Vein Thrombosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 AFP APOH F2 F5 F7 SERPINC1
2 endoplasmic reticulum lumen GO:0005788 9.35 AFP F2 F5 F7 SERPINC1
3 extracellular space GO:0005615 9.23 AFP APOH F2 F5 F7 SELP

Biological processes related to Portal Vein Thrombosis according to GeneCards Suite gene sharing:

(show all 15)
# Name GO ID Score Top Affiliating Genes
1 ER to Golgi vesicle-mediated transport GO:0006888 9.71 F2 F5 F7
2 cellular protein metabolic process GO:0044267 9.71 AFP F2 F5 SERPINC1
3 platelet degranulation GO:0002576 9.67 APOH F5 SELP SERPINE1
4 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.61 F2 JAK2 SELP
5 blood circulation GO:0008015 9.55 F5 MTHFR
6 blood coagulation GO:0007596 9.55 F2 F5 F7 JAK2 SERPINC1
7 signal peptide processing GO:0006465 9.52 F2 F7
8 fibrinolysis GO:0042730 9.51 F2 SERPINE1
9 regulation of blood coagulation GO:0030193 9.5 APOH F2 SERPINC1
10 blood coagulation, intrinsic pathway GO:0007597 9.49 APOH F2
11 negative regulation of blood coagulation GO:0030195 9.48 APOH SERPINE1
12 peptidyl-glutamic acid carboxylation GO:0017187 9.46 F2 F7
13 negative regulation of fibrinolysis GO:0051918 9.43 APOH F2 SERPINE1
14 hemostasis GO:0007599 9.26 F2 F5 F7 SERPINC1
15 positive regulation of blood coagulation GO:0030194 8.92 APOH F2 F7 SERPINE1

Molecular functions related to Portal Vein Thrombosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 9.26 F2 F7 JAK2 SERPINE1
2 lipopolysaccharide binding GO:0001530 9.16 F2 SELP
3 heparin binding GO:0008201 8.92 APOH F2 SELP SERPINC1

Sources for Portal Vein Thrombosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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