PTSD
MCID: PST028
MIFTS: 62

Post-Traumatic Stress Disorder (PTSD)

Categories: Mental diseases, Neuronal diseases

Aliases & Classifications for Post-Traumatic Stress Disorder

MalaCards integrated aliases for Post-Traumatic Stress Disorder:

Name: Post-Traumatic Stress Disorder 12 29 43 15 73
Stress Disorders, Post-Traumatic 44
Post Traumatic Stress Disorder 76
Posttraumatic Stress Disorder 15
Traumatic Neurosis 12
Ptsd 48

Classifications:



External Ids:

Disease Ontology 12 DOID:2055
ICD10 33 F43.1 F43.10
ICD9CM 35 309.81
MeSH 44 D013313
NCIt 50 C3389
SNOMED-CT 68 47505003
UMLS 73 C0038436

Summaries for Post-Traumatic Stress Disorder

MedlinePlus : 43 Post-traumatic stress disorder (PTSD) is a real illness. You can get PTSD after living through or seeing a traumatic event, such as war, a hurricane, sexual assault, physical abuse, or a bad accident. PTSD makes you feel stressed and afraid after the danger is over. It affects your life and the people around you. PTSD can cause problems like Flashbacks, or feeling like the event is happening again Trouble sleeping or nightmares Feeling alone Angry outbursts Feeling worried, guilty, or sad PTSD starts at different times for different people. Signs of PTSD may start soon after a frightening event and then continue. Other people develop new or more severe signs months or even years later. PTSD can happen to anyone, even children. Treatment may include talk therapy, medicines, or both. Treatment might take 6 to 12 weeks. For some people, it takes longer. NIH: National Institute of Mental Health

MalaCards based summary : Post-Traumatic Stress Disorder, also known as stress disorders, post-traumatic, is related to traumatic brain injury and anxiety, and has symptoms including nervousness An important gene associated with Post-Traumatic Stress Disorder is LINC01090 (Long Intergenic Non-Protein Coding RNA 1090), and among its related pathways/superpathways are Circadian entrainment and Amphetamine addiction. The drugs Oxytocin and Diazepam have been mentioned in the context of this disorder. Affiliated tissues include brain, eye and testes, and related phenotypes are homeostasis/metabolism and behavior/neurological

Disease Ontology : 12 An anxiety disorder which results from a traumatic experience that results in psychological trauma.

Wikipedia : 76 Posttraumatic stress disorder (PTSD)[note 1] is a mental disorder that can develop after a person is... more...

Related Diseases for Post-Traumatic Stress Disorder

Diseases related to Post-Traumatic Stress Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 257)
# Related Disease Score Top Affiliating Genes
1 traumatic brain injury 32.7 APOE BDNF COMT DRD2
2 anxiety 32.0 BDNF CNR1 COMT CRH HTR2A MAOA
3 brain injury 31.3 APOE BDNF COMT DRD2
4 depression 31.1 BDNF CRH HTR2A MAOA NR3C1 SLC6A4
5 alexithymia 30.3 COMT CRP DRD2 SLC6A4
6 fibromyalgia 30.3 COMT CRH HTR2A SLC6A4
7 sleep apnea 30.3 APOE CRP HTR2A IL1B
8 borderline personality disorder 30.2 BDNF COMT HTR2A MAOA NR3C1 SLC6A4
9 personality disorder 30.2 BDNF COMT DRD2 HTR2A MAOA SLC6A4
10 social phobia 30.2 DRD2 MAOA SLC6A4
11 burns 30.1 CRH CRP IL1B
12 substance abuse 30.1 BDNF COMT DRD2 MAOA SLC6A4
13 panic disorder 30.0 BDNF COMT CRH HTR2A MAOA SLC6A4
14 postpartum depression 29.9 BDNF COMT CRH MAOA SLC6A4
15 conduct disorder 29.9 COMT DRD2 MAOA SLC6A4
16 amnestic disorder 29.9 BDNF CNR1 PREP
17 schizoaffective disorder 29.9 BDNF COMT DRD2 HTR2A SLC6A4
18 obsessive-compulsive disorder 29.9 BDNF COMT CRH DRD2 HTR2A MAOA
19 avoidant personality disorder 29.9 MAOA SLC6A4
20 psychotic disorder 29.8 BDNF COMT DRD2 HTR2A MAOB SLC6A4
21 arteries, anomalies of 29.8 APOE CRP IL1B
22 autism 29.8 BDNF COMT DRD2 HTR2A MAOA SLC6A4
23 drug dependence 29.8 BDNF CNR1 CRH DRD2 SLC6A4
24 tobacco addiction 29.8 COMT DRD2 HTR2A MAOA SLC6A4
25 cannabis dependence 29.8 CNR1 COMT FAAH
26 mental depression 29.8 BDNF COMT CRH FKBP5 HTR2A MAOA
27 anorexia nervosa 29.8 BDNF COMT CRH HTR2A SLC6A4
28 generalized anxiety disorder 29.7 BDNF COMT DRD2 HTR2A MAOA SLC6A4
29 alzheimer disease 29.7 APOE BDNF CRH IL1B MAOB SLC6A4
30 eating disorder 29.7 BDNF CNR1 COMT CRH DRD2 SLC6A4
31 attention deficit-hyperactivity disorder 29.7 BDNF COMT DRD2 HTR2A MAOA MAOB
32 substance dependence 29.7 BDNF CNR1 DRD2 MAOA SLC6A4
33 major depressive disorder 29.7 APOE BDNF COMT CRH DRD2 FKBP5
34 schizophrenia 29.6 BDNF CNR1 COMT DRD2 HTR2A MAOA
35 paranoid schizophrenia 29.6 BDNF COMT HTR2A MAOA SLC6A4
36 bipolar i disorder 29.6 BDNF COMT HTR2A SLC6A4
37 bulimia nervosa 29.6 BDNF COMT HTR2A SLC6A4
38 serotonin syndrome 29.6 HTR2A MAOA MAOB SLC6A4
39 antisocial personality disorder 29.5 COMT DRD2 MAOA MAOB SLC6A4
40 bipolar disorder 29.5 BDNF COMT CRH DRD2 HTR2A MAOA
41 osteoporosis 29.5 APOE CNR1 CRP IL1B NR3C1
42 alcohol abuse 29.5 BDNF CNR1 DRD2 FAAH HTR2A SLC6A4
43 pathological gambling 29.5 DRD2 HTR2A MAOA MAOB SLC6A4
44 chronic fatigue syndrome 29.4 COMT CRH HTR2A IL1B MAOA NR3C1
45 disease of mental health 29.3 APOE BDNF CNR1 COMT CRH DRD2
46 mood disorder 29.2 BDNF COMT CRH DRD2 HTR2A MAOA
47 alcohol dependence 29.1 BDNF CNR1 COMT DRD2 FAAH HTR2A
48 migraine with or without aura 1 29.0 ADCYAP1 CNR1 COMT DRD2 HTR2A MAOA
49 parkinson disease, late-onset 28.7 ADCYAP1 APOE BDNF CNR1 COMT DRD2
50 multiple personality disorder 11.6

Comorbidity relations with Post-Traumatic Stress Disorder via Phenotypic Disease Network (PDN):


Anxiety Dysthymic Disorder
Major Depressive Disorder

Graphical network of the top 20 diseases related to Post-Traumatic Stress Disorder:



Diseases related to Post-Traumatic Stress Disorder

Symptoms & Phenotypes for Post-Traumatic Stress Disorder

UMLS symptoms related to Post-Traumatic Stress Disorder:


nervousness

MGI Mouse Phenotypes related to Post-Traumatic Stress Disorder:

46 (show all 14)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.45 ADCYAP1 ADCYAP1R1 APOE BDNF CNR1 COMT
2 behavior/neurological MP:0005386 10.43 ADCYAP1 ADCYAP1R1 APOE BDNF CNR1 COMT
3 growth/size/body region MP:0005378 10.25 ADCYAP1 ADCYAP1R1 APOE BDNF CNR1 CRH
4 mortality/aging MP:0010768 10.25 ADCYAP1 ADCYAP1R1 APOE BDNF CNR1 DRD2
5 nervous system MP:0003631 10.24 ADCYAP1 ADCYAP1R1 APOE BDNF CNR1 COMT
6 immune system MP:0005387 10.22 ADCYAP1 ADCYAP1R1 APOE COMT CRH CRP
7 integument MP:0010771 10.11 APOE BDNF CNR1 CRH DRD2 FAAH
8 adipose tissue MP:0005375 10.08 ADCYAP1 APOE CNR1 CRH DRD2 NR3C1
9 muscle MP:0005369 9.95 ADCYAP1 APOE DRD2 FAAH HTR2A NR3C1
10 no phenotypic analysis MP:0003012 9.92 ADCYAP1 ADCYAP1R1 APOE BDNF CNR1 CRH
11 normal MP:0002873 9.91 ADCYAP1R1 BDNF CNR1 CRH DRD2 FAAH
12 renal/urinary system MP:0005367 9.76 APOE COMT CRH DRD2 FKBP5 MAOB
13 reproductive system MP:0005389 9.61 ADCYAP1 ADCYAP1R1 APOE BDNF CNR1 COMT
14 taste/olfaction MP:0005394 8.92 APOE BDNF CNR1 DRD2

Drugs & Therapeutics for Post-Traumatic Stress Disorder

Drugs for Post-Traumatic Stress Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 387)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Oxytocin Approved, Vet_approved Phase 4,Phase 2,Phase 1,Not Applicable,Early Phase 1 50-56-6 439302 53477758
2
Diazepam Approved, Illicit, Investigational, Vet_approved Phase 4,Not Applicable 439-14-5 3016
3
Tramadol Approved, Investigational Phase 4,Not Applicable 27203-92-5 33741
4
Dronabinol Approved, Illicit Phase 4,Phase 2,Phase 1,Not Applicable 1972-08-3 16078
5
Fluoxetine Approved, Vet_approved Phase 4,Phase 3,Phase 1,Not Applicable 54910-89-3 3386
6
Propranolol Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 525-66-6 4946
7
Sertraline Approved Phase 4,Phase 3,Phase 2,Phase 1 79617-96-2 68617
8
Ethanol Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 64-17-5 702
9
Paroxetine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 61869-08-7 43815
10
Cycloserine Approved Phase 4,Phase 2,Phase 3,Not Applicable 68-41-7 6234 401
11
Mifepristone Approved, Investigational Phase 4,Phase 2,Phase 1,Not Applicable 84371-65-3 55245
12
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 51-61-6, 62-31-7 681
13
Citalopram Approved Phase 4,Phase 3,Phase 2,Not Applicable 59729-33-8 2771
14
Prazosin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 19216-56-9 4893
15
Hydrocortisone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 50-23-7 5754
16
Hydrocortisone acetate Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 50-03-3
17
Norepinephrine Approved Phase 4,Phase 3,Phase 1,Early Phase 1,Not Applicable 51-41-2 439260
18
Haloperidol Approved Phase 4,Phase 3 52-86-8 3559
19
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 2,Not Applicable 59467-70-8 4192
20
Lorazepam Approved Phase 4,Not Applicable 846-49-1 3958
21
Ketamine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 6740-88-1 3821
22
Asenapine Approved Phase 4 65576-45-6, 85650-56-2 3001386
23
Eszopiclone Approved, Investigational Phase 4,Phase 3 138729-47-2 969472
24
Naltrexone Approved, Investigational, Vet_approved Phase 4,Phase 2 16590-41-3 5360515
25
Topiramate Approved Phase 4,Phase 2,Phase 3,Not Applicable 97240-79-4 5284627
26
Clonazepam Approved, Illicit Phase 4 1622-61-3 2802
27
Mianserin Approved, Investigational Phase 4 24219-97-4 4184
28
Histamine Approved, Investigational Phase 4,Not Applicable 51-45-6, 75614-87-8 774
29
Mirtazapine Approved Phase 4,Not Applicable 61337-67-5, 85650-52-8 4205
30
Ziprasidone Approved Phase 4,Phase 3 146939-27-7 60854
31 tannic acid Approved Phase 4,Phase 3,Phase 2,Not Applicable
32
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 94-09-7, 1994-09-7 2337
33
Memantine Approved, Investigational Phase 4 19982-08-2 4054
34
Risperidone Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 106266-06-2 5073
35
Carbon monoxide Approved, Investigational Phase 4,Not Applicable 630-08-0 281
36
Doxazosin Approved Phase 4,Phase 2,Phase 1 74191-85-8 3157
37
Pregabalin Approved, Illicit, Investigational Phase 4,Phase 3 148553-50-8 5486971
38
Guanfacine Approved, Investigational Phase 4,Phase 1 29110-47-2 3519
39
Valproic Acid Approved, Investigational Phase 4,Phase 3 99-66-1 3121
40
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3 437-38-7 3345
41
Vortioxetine Approved, Investigational Phase 4,Phase 3 508233-74-7 9966051
42
Suvorexant Approved, Investigational Phase 4 1030377-33-3
43
Minocycline Approved, Investigational Phase 4 10118-90-8 5281021
44
Levodopa Approved Phase 4 59-92-7 6047
45
Estradiol Approved, Investigational, Vet_approved Phase 4,Not Applicable 50-28-2 5757
46 Estradiol valerate Approved, Investigational, Vet_approved Phase 4,Not Applicable 979-32-8
47
Polyestradiol phosphate Approved Phase 4,Not Applicable 28014-46-2
48
Lormetazepam Approved Phase 4 848-75-9 13314
49
Melatonin Approved, Nutraceutical, Vet_approved Phase 4,Not Applicable 73-31-4 896
50 Oxytocics Phase 4,Phase 2,Phase 1,Not Applicable,Early Phase 1

Interventional clinical trials:

(show top 50) (show all 1462)
# Name Status NCT ID Phase Drugs
1 Oxytocin and Affect Processing in Posttraumatic Stress Disorder Unknown status NCT02546570 Phase 4 Oxytocin;Placebo
2 Transcranial Magnetic Stimulation for Post-Traumatic Stress Disorder Unknown status NCT00134446 Phase 4
3 Prevention of Posttraumatic Stress Disorder (PTSD) With Diazepam Unknown status NCT01221883 Phase 4 Diazepam
4 Tramadol Extended-Release (ER) for Posttraumatic Stress Disorder (PTSD) Unknown status NCT01517711 Phase 4 Tramadol;Placebo
5 Add on Study on Δ9-THC Treatment for Posttraumatic Stress Disorders (PTSD) Unknown status NCT00965809 Phase 4 Tetrahydrocannabinol
6 The Effect of 21-Days Intranasal Oxytocin on Patients With Post Traumatic Stress Disorder (PTSD) Unknown status NCT02336568 Phase 4 Oxytoine;PLACEBO
7 Predictors of Treatment Response to Fluoxetine in PTSD Following a Recent History of War Zone Stress Exposure Unknown status NCT00633685 Phase 4 Fluoxetine;Placebo
8 A Randomized Cross Over Trial of Two Treatments for Obstructive Sleep Apnea in Veterans With Post Traumatic Stress Disorder Unknown status NCT01535586 Phase 4
9 Management of Chronic Pain in Military Patients With Injuries Sustained During Active Duty Unknown status NCT01616342 Phase 4
10 An Open Label Pilot Study of Adjunctive Asenapine for the Treatment of Posttraumatic Stress Disorder Completed NCT01587118 Phase 4 Adjunctive asenapine
11 Effect of Propranolol on Preventing Posttraumatic Stress Disorder Completed NCT00158262 Phase 4 Propranolol;Placebo
12 Cognitive Behavioral Therapy Versus Sertraline in the Treatment of Post-Traumatic Stress Disorder Completed NCT00391430 Phase 4 Sertraline
13 Eszopiclone for the Treatment of Posttraumatic Stress Disorder Completed NCT01605253 Phase 4 Eszopiclone;Placebo
14 Treatment for Alcoholism and Post-Traumatic Stress Disorder (Naltrexone) Completed NCT00006489 Phase 4 Naltrexone;Placebo
15 Placebo Controled Clinical Trial Using Topiramate To Treat Posttraumatic Stress Disorder (PTSD) Patients. Completed NCT00725920 Phase 4 Topiramate;placebo control group
16 PROlonGed ExpoSure Sertraline Completed NCT01524133 Phase 4 Sertraline
17 Eszopiclone for Sleep Disturbance and Nightmares in Post-Traumatic Stress Disorder Completed NCT00120250 Phase 4 Eszopiclone
18 Clonazepam and Paroxetine for Rapid Treatment of Post-Traumatic Stress Disorder Completed NCT00025740 Phase 4 clonazepam and paroxetine
19 Developing Memory Reconsolidation Blockers as Novel Posttraumatic Stress Disorder (PTSD) Treatments Completed NCT01490697 Phase 4 Mifepristone;d-Cycloserine;Placebo-matching Mifepristone;Placebo-matching d-Cycloserine (DCS)
20 Combined Mirtazapine and SSRI Treatment of PTSD: A Placebo-Controlled Trial Completed NCT01178671 Phase 4 Mirtazapine;Sertraline
21 Geodon (Ziprasidone) for Posttraumatic Stress Disorder Completed NCT00208208 Phase 4 Ziprasidone
22 Topiramate in the Treatment of Posttraumatic Stress Disorder in Civilians Completed NCT00208130 Phase 4 Topiramate
23 Secondary Prevention With Paroxetine vs. Placebo in Subthreshold Posttraumatic Stress Disorder (PTSD) Completed NCT00560612 Phase 4 Paroxetine;Placebo
24 Brain Markers of Treatment Response in Post-Traumatic Stress Disorder (PTSD) Completed NCT00700999 Phase 4 Paroxetine
25 Vilazodone for the Treatment of Posttraumatic Stress Disorder Completed NCT01715519 Phase 4 Treatment (Viibryd)
26 Neural Circuits in Women With Abuse and Posttraumatic Stress Disorder Completed NCT01681849 Phase 4 Placebo;Paroxetine
27 Topiramate Treatment of Alcohol Use Disorders in Veterans With Post Traumatic Stress Disorder (PTSD): A Pilot Controlled Trial of Augmentation Therapy Completed NCT01087736 Phase 4 Topiramate
28 Effects of Paxil CR on Neural Circuits in Posttraumatic Stress Disorder (PTSD) Completed NCT00672776 Phase 4 paroxetine;placebo
29 Topiramate in the Treatment of Post Traumatic Stress Disorder (PTSD) Completed NCT00203463 Phase 4 topiramate
30 A Psychophysiologic Study of Weakening Traumatic Combat Memories With Post-Reactivation Propranolol Completed NCT00709735 Phase 4 Propranolol;Placebo
31 Combination Treatment for Posttraumatic Stress Disorder (PTSD) After the World Trade Center (WTC) Attack Completed NCT01130103 Phase 4 Paroxetine
32 The Effect of Intranasal Oxytocin on Emphatic Abilities in Patients With Post Traumatic Stress Disorder (PTSD) Completed NCT01325168 Phase 4 syntocinon nasal spray;placebo nasal spray
33 An Open-Label Trial of Memantine for Cognitive Impairment in Patients With Post-Traumatic Stress Disorder Completed NCT02258828 Phase 4 Memantine
34 Effects of Escitalopram on Autonomic Reactivity in Post Traumatic Stress Disorder Completed NCT01271244 Phase 4 Escitalopram
35 A Study of Sertraline to Prevent PTSD Completed NCT00182078 Phase 4 Placebo;Sertraline
36 Serotonin Selective Reuptake Inhibitor Treatment of Dual Diagnosis Post-traumatic Stress Disorder and Alcohol Problems Completed NCT02504931 Phase 4 Sertraline;Placebo
37 Reducing Suicidal Ideation Through Treatment of Nightmares-Post Traumatic Stress Disorder (PTSD) Completed NCT02199652 Phase 4 Prazosin;Placebo
38 Risperidone in the Treatment of PTSD in Women Survivors of Domestic Abuse and Rape Trauma Completed NCT00208182 Phase 4 Risperidone
39 The Outcome of Treatment of Traumatised Refugees With Psychotherapy and/or Antidepressants Completed NCT00917397 Phase 4 Sertraline
40 Telemedicine Outreach for Post Traumatic Stress in CBOCs Completed NCT00821678 Phase 4
41 Veteran Stress and Learning Study Completed NCT00674570 Phase 4 Hydrocortisone;D-Cycloserine;Placebo
42 Quetiapine Treatment for Post-Traumatic Stress Disorder (PTSD) Completed NCT00237393 Phase 4 Quetiapine;Placebo
43 The Treatment of Traumatised Refugees With Sertraline Versus Venlafaxine in Combination With Psychotherapy Completed NCT01569685 Phase 4 Venlafaxine;Sertraline
44 A Placebo-Controlled Study of Mirtazapine for PTSD Completed NCT00302107 Phase 4 Mirtazapine;Placebo
45 Evaluation of Stress Disorders Completed NCT00050804 Phase 4 sertraline
46 Veterans Individual Placement and Support Towards Advancing Recovery Completed NCT01817712 Phase 4
47 Primary Care Intervention Strategy for Anxiety Disorders Completed NCT00347269 Phase 4 Psychotropic medication optimization
48 Prazosin Treatment for Combat Trauma PTSD (Post-Traumatic Stress Disorder) Nightmares and Sleep Disturbance Completed NCT00108420 Phase 4 Prazosin
49 Pilot Study of Pharmaceutical and Behavioral Interventions to Treat Anxiety Disorders Completed NCT01631682 Phase 4 Propranolol;Mifepristone;Intranasal oxytocin
50 Influence of Hydrocortisone on Immunologic Markers and Health Care Related Quality of Life in Patients After Cardiac Surgery Completed NCT00490828 Phase 4 Hydrocortisone

Search NIH Clinical Center for Post-Traumatic Stress Disorder

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: stress disorders, post-traumatic

Genetic Tests for Post-Traumatic Stress Disorder

Genetic tests related to Post-Traumatic Stress Disorder:

# Genetic test Affiliating Genes
1 Post-Traumatic Stress Disorder 29

Anatomical Context for Post-Traumatic Stress Disorder

MalaCards organs/tissues related to Post-Traumatic Stress Disorder:

41
Brain, Eye, Testes, Amygdala, Heart, Cortex, Lung

Publications for Post-Traumatic Stress Disorder

Articles related to Post-Traumatic Stress Disorder:

(show top 50) (show all 1545)
# Title Authors Year
1
The opioid system in stress-induced memory disorders: From basic mechanisms to clinical implications in post-traumatic stress disorder and Alzheimer's disease. ( 30118823 )
2019
2
A systematic review and meta-analysis of group treatments for adults with symptoms associated with complex post-traumatic stress disorder. ( 30261446 )
2019
3
Severe and protracted sleep disruptions in mouse model of post-traumatic stress disorder. ( 29346627 )
2018
4
The long-term impact of post traumatic stress disorder on recovery from heroin dependence. ( 29706174 )
2018
5
A Systematic Review of Interleukin-1I^ in Post-Traumatic Stress Disorder: Evidence from Human and Animal Studies. ( 29328883 )
2018
6
The Use of Eye-Movement Desensitization Reprocessing (EMDR) Therapy in Treating Post-traumatic Stress Disorder-A Systematic Narrative Review. ( 29928250 )
2018
7
Emergency room intervention to prevent post concussion-like symptoms and post-traumatic stress disorder. A pilot randomized controlled study of a brief eye movement desensitization and reprocessing intervention versus reassurance or usual care. ( 29894921 )
2018
8
DBS in Treatment of Post-Traumatic Stress Disorder. ( 29361705 )
2018
9
The role of negative cognitions, emotion regulation strategies, and attachment style in complex post-traumatic stress disorder: Implications for new and existing therapies. ( 29355986 )
2018
10
The Transcendental Meditation Program's Impact on the Symptoms of Post-traumatic Stress Disorder of Veterans: An Uncontrolled Pilot Study. ( 29401353 )
2018
11
When Post-Traumatic Stress Disorder and Charles Bonnet Syndrome Become Lewy Body Dementia. ( 29778582 )
2018
12
Military-Tailored Yoga for Veterans with Post-traumatic Stress Disorder. ( 29415222 )
2018
13
Psychological interventions for post-traumatic stress disorder in refugees and asylum seekers: A systematic review and meta-analysis. ( 29936342 )
2018
14
Associations of trauma exposure and post-traumatic stress disorder with the activity of the renin-angiotensin-aldosterone-system in the general population. ( 29909779 )
2018
15
Application of data pooling to longitudinal studies of early post-traumatic stress disorder (PTSD): the International Consortium to Predict PTSD (ICPP) project. ( 29938009 )
2018
16
Comorbid insomnia and sleep apnea in Veterans with post-traumatic stress disorder. ( 29330769 )
2018
17
Multimodal Treatment With ECT for Identity Integration in a Patient With Dissociative Identity Disorder, Complex Post-traumatic Stress Disorder, and Major Depressive Disorder: A Rare Case Report. ( 29977211 )
2018
18
Regulation of threat in post-traumatic stress disorder: Associations between inhibitory control and dissociative symptoms. ( 29409740 )
2018
19
Longitudinal trajectories of post-traumatic stress disorder (PTSD) after birth and associated risk factors. ( 29331697 )
2018
20
Cotinine: A Therapy for Memory Extinction in Post-traumatic Stress Disorder. ( 29335846 )
2018
21
Trial of Prazosin for Post-Traumatic Stress Disorder in Military Veterans. ( 29414272 )
2018
22
trans-Resveratrol ameliorates anxiety-like behaviors and fear memory deficits in a rat model of post-traumatic stress disorder. ( 29373817 )
2018
23
Depression, Anxiety, Post-traumatic Stress Disorder and a History of Pervasive Gender-Based Violence Among Women Asylum Seekers Who Have Undergone Female Genital Mutilation/Cutting: A Retrospective Case Review. ( 29968003 )
2018
24
From post-traumatic stress disorder to absolute dependence in an intensive care unit: reflections on a clinical account. ( 29925572 )
2018
25
Acquired Stuttering in Veterans of the Wars in Iraq and Afghanistan: The Role of Traumatic Brain Injury, Post-Traumatic Stress Disorder, and Medications. ( 29912436 )
2018
26
Augmenting inpatient treatment for post-traumatic stress disorder with a computerised cognitive bias modification procedure targeting appraisals (CBM-App): protocol for a randomised controlled trial. ( 29961004 )
2018
27
A review on inflammatory cytokine-induced alterations of the brain as potential neural biomarkers in post-traumatic stress disorder. ( 29932946 )
2018
28
Melatonin ameliorates cognitive memory by regulation of cAMP-response element-binding protein expression and the anti-inflammatory response in a rat model of post-traumatic stress disorder. ( 29973144 )
2018
29
Smaller hippocampal volume following sexual assault in women is associated with post-traumatic stress disorder. ( 29952088 )
2018
30
Undetected post-traumatic stress disorder in secondary-care mental health services: systematic review. ( 29433609 )
2018
31
Post-Traumatic Stress Disorder Delineating the Progression and Underlying Mechanisms Following Blast Traumatic Brain Injury. ( 29888766 )
2018
32
Cortical surface area reduction in identification of subjects at high risk for post-traumatic stress disorder: A pilot study. ( 29361837 )
2018
33
Veterans' Perspectives on Fitbit Use in Treatment for Post-Traumatic Stress Disorder: An Interview Study. ( 29907556 )
2018
34
Influence of adjuvant mindfulness-based cognitive therapy (MBCT) on symptoms of post-traumatic stress disorder (PTSD) in veterans - results from a randomized control study. ( 29893182 )
2018
35
Effect of Post-Traumatic Stress Disorder on Cognitive Function and Covert Hepatic Encephalopathy Diagnosis in Cirrhotic Veterans. ( 29313245 )
2018
36
Intermittent hypoxia improves behavioral and adrenal gland dysfunction induced by post-traumatic stress disorder in rats. ( 29927732 )
2018
37
Familial risk for psychiatric disorders in military veterans who have post-traumatic stress disorder with psychosis: a retrospective electronic record review. ( 29384891 )
2018
38
To lose an unborn child: Post-traumatic stress disorder and major depressive disorder following pregnancy loss among Israeli women. ( 29934032 )
2018
39
Influence of early stress on memory reconsolidation: Implications for post-traumatic stress disorder treatment. ( 29352277 )
2018
40
Interaction between early-life stress and FKBP5 gene variants in major depressive disorder and post-traumatic stress disorder: A systematic review and meta-analysis. ( 28850857 )
2018
41
Prison employment and post-traumatic stress disorder: Risk and protective factors. ( 29896918 )
2018
42
The Effectiveness of Using Neurofeedback in the Treatment of Post-Traumatic Stress Disorder: A Systematic Review. ( 29890906 )
2018
43
Long-term sequelae of acute respiratory distress syndrome caused by severe community-acquired pneumonia: Delirium-associated cognitive impairment and post-traumatic stress disorder. ( 29609489 )
2018
44
Prevalence of post-traumatic stress disorder, acute stress disorder and depression following violence related injury treated at the emergency department: a systematic review. ( 30253782 )
2018
45
Association Between Anxiety, Depression, and Post-traumatic Stress Disorder and Outcomes After Ischemic Stroke. ( 30450075 )
2018
46
Oleuropein reduces anxiety-like responses by activating of serotonergic and neuropeptide Y (NPY)-ergic systems in a rat model of post-traumatic stress disorder. ( 30460087 )
2018
47
Anxiety, Depression and Post Traumatic Stress Disorder after critical illness: a UK-wide prospective cohort study. ( 30466485 )
2018
48
Dental anxiety in relation to torture experiences and symptoms of post-traumatic stress disorder. ( 30444297 )
2018
49
Silymarin Prevents Memory Impairments, Anxiety, and Depressive-Like Symptoms in a Rat Model of Post-Traumatic Stress Disorder. ( 30153692 )
2018
50
Tetramethylpyrazine reverses anxiety-like behaviors in a rat model of post-traumatic stress disorder. ( 30181699 )
2018

Variations for Post-Traumatic Stress Disorder

Expression for Post-Traumatic Stress Disorder

Search GEO for disease gene expression data for Post-Traumatic Stress Disorder.

Pathways for Post-Traumatic Stress Disorder

Pathways related to Post-Traumatic Stress Disorder according to GeneCards Suite gene sharing:

(show all 13)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.82 ADCYAP1R1 COMT DRD2 FKBP5 MAOA MAOB
2
Show member pathways
11.77 BDNF DRD2 MAOA MAOB
3 11.73 HTR2A MAOA MAOB SLC6A4
4
Show member pathways
11.56 COMT MAOA MAOB
5 11.44 ADCYAP1 ADCYAP1R1 BDNF HTR2A IL1B MAOA
6 11.29 APOE IL1B NR3C1
7
Show member pathways
11.24 IL1B MAOA SLC6A4
8 10.94 HTR2A MAOA SLC6A4
9
Show member pathways
10.85 COMT MAOA SLC6A4
10
Show member pathways
10.64 MAOA MAOB
11
Show member pathways
10.55 ADCYAP1 ADCYAP1R1
12
Show member pathways
10.51 COMT MAOA MAOB
13 10.28 COMT MAOA MAOB

GO Terms for Post-Traumatic Stress Disorder

Cellular components related to Post-Traumatic Stress Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 dendrite GO:0030425 9.65 APOE BDNF COMT DRD2 HTR2A
2 axon GO:0030424 9.55 BDNF CNR1 COMT DRD2 HTR2A
3 cell body fiber GO:0070852 9.32 ADCYAP1 HTR2A
4 integral component of postsynaptic membrane GO:0099055 9.13 DRD2 HTR2A SLC6A4
5 integral component of presynaptic membrane GO:0099056 8.92 CNR1 DRD2 HTR2A SLC6A4

Biological processes related to Post-Traumatic Stress Disorder according to GeneCards Suite gene sharing:

(show all 30)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.93 ADCYAP1 CRH CRP IL1B SLC6A4
2 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.9 ADCYAP1 DRD2 HTR2A IL1B
3 positive regulation of neuron projection development GO:0010976 9.82 ADCYAP1 APOE CNR1
4 response to estradiol GO:0032355 9.81 ADCYAP1R1 IL1B SLC6A4
5 response to lipopolysaccharide GO:0032496 9.81 CNR1 COMT IL1B MAOB
6 response to toxic substance GO:0009636 9.8 DRD2 MAOB SLC6A4
7 female pregnancy GO:0007565 9.79 ADCYAP1 COMT CRH
8 negative regulation of cell death GO:0060548 9.73 ADCYAP1R1 CRH DRD2
9 sensory perception of pain GO:0019233 9.7 ADCYAP1 CNR1 HTR2A
10 response to cocaine GO:0042220 9.65 CNR1 CRH DRD2
11 synaptic transmission, dopaminergic GO:0001963 9.64 CRH DRD2
12 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.63 APOE IL1B
13 dopamine metabolic process GO:0042417 9.63 COMT DRD2
14 locomotory exploration behavior GO:0035641 9.61 APOE CRH
15 regulation of synaptic transmission, GABAergic GO:0032228 9.61 CNR1 DRD2
16 response to morphine GO:0043278 9.61 CNR1 DRD2 IL1B
17 catecholamine metabolic process GO:0006584 9.59 COMT MAOA
18 negative regulation of potassium ion transport GO:0043267 9.58 ADCYAP1 HTR2A
19 negative regulation of synaptic transmission, glutamatergic GO:0051967 9.58 DRD2 HTR2A
20 activation of phospholipase C activity GO:0007202 9.58 ADCYAP1R1 BDNF HTR2A
21 positive regulation of growth hormone secretion GO:0060124 9.57 ADCYAP1 DRD2
22 response to drug GO:0042493 9.56 ADCYAP1R1 COMT CRH DRD2 HTR2A IL1B
23 memory GO:0007613 9.55 BDNF CNR1 HTR2A IL1B SLC6A4
24 positive regulation of cAMP-mediated signaling GO:0043950 9.54 ADCYAP1 ADCYAP1R1 CRH
25 neurotransmitter catabolic process GO:0042135 9.5 COMT MAOA MAOB
26 positive regulation of fever generation GO:0031622 9.49 CNR1 IL1B
27 negative regulation of dopamine secretion GO:0033602 9.46 CNR1 DRD2
28 dopamine catabolic process GO:0042420 9.43 COMT MAOA MAOB
29 response to ethanol GO:0045471 9.17 ADCYAP1 ADCYAP1R1 CNR1 CRH DRD2 IL1B
30 G protein-coupled receptor signaling pathway GO:0007186 10.09 ADCYAP1 ADCYAP1R1 APOE CNR1 CRH DRD2

Molecular functions related to Post-Traumatic Stress Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 serotonin binding GO:0051378 9.16 HTR2A SLC6A4
2 drug binding GO:0008144 9.13 CNR1 DRD2 HTR2A
3 primary amine oxidase activity GO:0008131 8.62 MAOA MAOB

Sources for Post-Traumatic Stress Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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