MCID: PST028
MIFTS: 58

Post-Traumatic Stress Disorder

Categories: Mental diseases, Neuronal diseases

Aliases & Classifications for Post-Traumatic Stress Disorder

MalaCards integrated aliases for Post-Traumatic Stress Disorder:

Name: Post-Traumatic Stress Disorder 12 29 43 15 73
Stress Disorders, Post-Traumatic 44
Post Traumatic Stress Disorder 76
Traumatic Neurosis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2055
ICD10 33 F43.1 F43.10
ICD9CM 35 309.81
MeSH 44 D013313
NCIt 50 C3389
SNOMED-CT 68 192415000 47505003
UMLS 73 C0038436

Summaries for Post-Traumatic Stress Disorder

MedlinePlus : 43 Post-traumatic stress disorder (PTSD) is a real illness. You can get PTSD after living through or seeing a traumatic event, such as war, a hurricane, sexual assault, physical abuse, or a bad accident. PTSD makes you feel stressed and afraid after the danger is over. It affects your life and the people around you. PTSD can cause problems like Flashbacks, or feeling like the event is happening again Trouble sleeping or nightmares Feeling alone Angry outbursts Feeling worried, guilty, or sad PTSD starts at different times for different people. Signs of PTSD may start soon after a frightening event and then continue. Other people develop new or more severe signs months or even years later. PTSD can happen to anyone, even children. Treatment may include talk therapy, medicines, or both. Treatment might take 6 to 12 weeks. For some people, it takes longer. NIH: National Institute of Mental Health

MalaCards based summary : Post-Traumatic Stress Disorder, also known as stress disorders, post-traumatic, is related to traumatic brain injury and brain injury, and has symptoms including nervousness An important gene associated with Post-Traumatic Stress Disorder is LINC01090 (Long Intergenic Non-Protein Coding RNA 1090
The non-coding RNA gene may play a crucial role in shaping the landscape of gene regulation with putative pathological effects that lead to phenotypic differences
Dysfunction Pattern: Regulation), and among its related pathways/superpathways are Circadian entrainment and Amphetamine addiction. The drugs Diazepam and Tramadol have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and eye, and related phenotypes are homeostasis/metabolism and behavior/neurological

Disease Ontology : 12 An anxiety disorder which results from a traumatic experience that results in psychological trauma.

Wikipedia : 76 Posttraumatic stress disorder (PTSD)[note 1] is a mental disorder that can develop after a person is... more...

Related Diseases for Post-Traumatic Stress Disorder

Diseases related to Post-Traumatic Stress Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 136)
# Related Disease Score Top Affiliating Genes
1 traumatic brain injury 33.2 BDNF COMT DRD2
2 brain injury 31.5 BDNF COMT DRD2
3 burns 30.7 CRH IL1B
4 chronic pain 30.7 CNR1 COMT
5 anxiety 30.5 BDNF CNR1 COMT CRH HTR2A MAOA
6 depression 30.3 BDNF CRH HTR2A MAOA NR3C1 SLC6A4
7 alexithymia 29.9 COMT CRP DRD2 SLC6A4
8 drug dependence 29.9 BDNF CNR1 CRH DRD2 SLC6A4
9 fibromyalgia 29.9 COMT CRH HTR2A SLC6A4
10 generalized anxiety disorder 29.5 BDNF DRD2 HTR2A MAOA SLC6A4
11 substance abuse 29.4 BDNF COMT DRD2 MAOA SLC6A4
12 panic disorder 29.3 BDNF COMT CRH HTR2A MAOA SLC6A4
13 substance dependence 29.3 BDNF CNR1 DRD2 MAOA SLC6A4
14 paranoid schizophrenia 29.2 BDNF COMT HTR2A MAOA SLC6A4
15 serotonin syndrome 29.1 HTR2A MAOA MAOB SLC6A4
16 chronic fatigue syndrome 29.1 COMT CRH IL1B MAOA NR3C1 SLC6A4
17 obsessive-compulsive disorder 29.0 BDNF COMT DRD2 HTR2A MAOA SLC6A4
18 borderline personality disorder 28.9 BDNF COMT FKBP5 HTR2A MAOA NR3C1
19 autism 28.7 BDNF COMT DRD2 HTR2A MAOA SLC6A4
20 personality disorder 28.5 BDNF COMT DRD2 HTR2A MAOA MAOB
21 psychotic disorder 28.4 BDNF CNR1 COMT DRD2 HTR2A MAOB
22 bipolar disorder 28.4 BDNF COMT CRH DRD2 HTR2A MAOA
23 attention deficit-hyperactivity disorder 28.2 BDNF COMT DRD2 HTR2A MAOA MAOB
24 major depressive disorder 27.9 BDNF COMT CRH DRD2 FKBP5 HTR2A
25 schizophrenia 27.7 BDNF CNR1 COMT DRD2 HTR2A MAOA
26 mood disorder 27.4 BDNF COMT CRH DRD2 HTR2A MAOA
27 alcohol dependence 26.9 BDNF CNR1 COMT DRD2 FAAH HTR2A
28 multiple personality disorder 11.2
29 allergic urticaria 10.8 CRH NR3C1
30 schizophreniform disorder 10.7 COMT DRD2
31 alcohol-induced mental disorder 10.6 DRD2 SLC6A4
32 renal infectious disease 10.5 CRP NR3C1
33 gilles de la tourette syndrome 10.5 BDNF COMT DRD2
34 alzheimer disease 5 10.5 HTR2A SLC6A4
35 phobia, specific 10.5 COMT MAOA
36 cannabis abuse 10.5 BDNF CNR1
37 tardive dyskinesia 10.4 COMT DRD2 HTR2A
38 acute stress disorder 10.4
39 alcoholic psychosis 10.4 DRD2 HTR2A SLC6A4
40 periodic limb movement disorder 10.3 DRD2 HTR2A SLC6A4
41 bruxism 10.3 DRD2 HTR2A SLC6A4
42 social phobia 10.3 DRD2 MAOA SLC6A4
43 aging 10.3
44 drug-induced mental disorder 10.3 CNR1 DRD2 HTR2A
45 drug psychosis 10.3 CNR1 DRD2 HTR2A
46 phobic disorder 10.3 COMT MAOA SLC6A4
47 synucleinopathy 10.2 BDNF COMT MAOB
48 toxic encephalopathy 10.2 BDNF IL1B MAOB
49 psychosexual disorder 10.2 HTR2A SLC6A4
50 central nervous system disease 10.2 BDNF IL1B MAOB

Comorbidity relations with Post-Traumatic Stress Disorder via Phenotypic Disease Network (PDN):


Anxiety Dysthymic Disorder
Major Depressive Disorder

Graphical network of the top 20 diseases related to Post-Traumatic Stress Disorder:



Diseases related to Post-Traumatic Stress Disorder

Symptoms & Phenotypes for Post-Traumatic Stress Disorder

UMLS symptoms related to Post-Traumatic Stress Disorder:


nervousness

MGI Mouse Phenotypes related to Post-Traumatic Stress Disorder:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.33 CRP DRD2 BDNF CNR1 FAAH FKBP5
2 behavior/neurological MP:0005386 10.31 ADCYAP1R1 DRD2 BDNF CNR1 FAAH COMT
3 mortality/aging MP:0010768 10.1 ADCYAP1R1 BDNF DRD2 FAAH CNR1 ADCYAP1
4 nervous system MP:0003631 10.1 ADCYAP1R1 DRD2 BDNF CNR1 FAAH COMT
5 integument MP:0010771 9.97 CRH BDNF DRD2 CNR1 FAAH IL1B
6 adipose tissue MP:0005375 9.93 CRH DRD2 CNR1 ADCYAP1 NR3C1 PREP
7 no phenotypic analysis MP:0003012 9.7 CRH ADCYAP1R1 BDNF DRD2 CNR1 ADCYAP1
8 normal MP:0002873 9.61 ADCYAP1R1 DRD2 BDNF CNR1 FAAH CRH
9 renal/urinary system MP:0005367 9.17 DRD2 COMT CRH PREP FKBP5 MAOB

Drugs & Therapeutics for Post-Traumatic Stress Disorder

Drugs for Post-Traumatic Stress Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 376)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Diazepam Approved, Illicit, Investigational, Vet_approved Phase 4,Not Applicable 439-14-5 3016
2
Tramadol Approved, Investigational Phase 4,Not Applicable 27203-92-5 33741
3
Dronabinol Approved, Illicit Phase 4,Phase 2,Phase 1,Not Applicable 1972-08-3 16078
4
Oxytocin Approved, Vet_approved Phase 4,Phase 2,Phase 1,Not Applicable,Early Phase 1 50-56-6 439302 53477758
5
Fluoxetine Approved, Vet_approved Phase 4,Phase 3,Phase 1,Not Applicable 54910-89-3 3386
6
Propranolol Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 525-66-6 4946
7
Sertraline Approved Phase 4,Phase 3,Phase 2,Phase 1 79617-96-2 68617
8
Ethanol Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 64-17-5 702
9
Paroxetine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 61869-08-7 43815
10
Cycloserine Approved Phase 4,Phase 2,Phase 3,Not Applicable 68-41-7 401 6234
11
Mifepristone Approved, Investigational Phase 4,Phase 2,Phase 1,Not Applicable 84371-65-3 55245
12
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 51-61-6, 62-31-7 681
13
Citalopram Approved Phase 4,Phase 3,Phase 2,Not Applicable 59729-33-8 2771
14
Hydrocortisone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 50-23-7 5754
15
Norepinephrine Approved Phase 4,Phase 3,Phase 1,Early Phase 1,Not Applicable 51-41-2 439260
16
Prazosin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 19216-56-9 4893
17
Lorazepam Approved Phase 4,Not Applicable 846-49-1 3958
18
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 2,Not Applicable 59467-70-8 4192
19
Ketamine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 6740-88-1 3821
20
Asenapine Approved Phase 4 85650-56-2, 65576-45-6 3001386
21
Eszopiclone Approved, Investigational Phase 4 138729-47-2 969472
22
Naltrexone Approved, Investigational, Vet_approved Phase 4,Phase 2 16590-41-3 5360515
23
Topiramate Approved Phase 4,Phase 2,Phase 3,Not Applicable 97240-79-4 5284627
24
Clonazepam Approved, Illicit Phase 4 1622-61-3 2802
25
Histamine Approved, Investigational Phase 4,Not Applicable 75614-87-8, 51-45-6 774
26
Mianserin Approved, Investigational Phase 4 24219-97-4 4184
27
Mirtazapine Approved Phase 4,Not Applicable 85650-52-8, 61337-67-5 4205
28
Ziprasidone Approved Phase 4,Phase 3 146939-27-7 60854
29
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 1994-09-7, 94-09-7 2337
30
Memantine Approved, Investigational Phase 4 19982-08-2 4054
31
Risperidone Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 106266-06-2 5073
32
Haloperidol Approved Phase 4,Phase 3 52-86-8 3559
33
Carbon monoxide Approved, Investigational Phase 4 630-08-0 281
34
Doxazosin Approved Phase 4,Phase 2,Phase 1 74191-85-8 3157
35
Pregabalin Approved, Illicit, Investigational Phase 4,Phase 3 148553-50-8 5486971
36
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3 437-38-7 3345
37
Guanfacine Approved, Investigational Phase 4,Phase 1 29110-47-2 3519
38
Valproic Acid Approved, Investigational Phase 4,Phase 3 99-66-1 3121
39
Vortioxetine Approved, Investigational Phase 4,Phase 3 508233-74-7 9966051
40
Suvorexant Approved, Investigational Phase 4 1030377-33-3
41
Minocycline Approved, Investigational Phase 4 10118-90-8 5281021
42
Levodopa Approved Phase 4 59-92-7 6047
43
Estradiol Approved, Investigational, Vet_approved Phase 4,Not Applicable 50-28-2 5757
44 Estradiol valerate Approved, Investigational, Vet_approved Phase 4,Not Applicable 979-32-8
45
Polyestradiol phosphate Approved Phase 4,Not Applicable 28014-46-2
46
Lormetazepam Approved Phase 4 848-75-9 13314
47 tannic acid Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Not Applicable
48
Melatonin Approved, Nutraceutical, Vet_approved Phase 4,Not Applicable 73-31-4 896
49
Butyric Acid Experimental, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 107-92-6 264
50 Adjuvants, Anesthesia Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

Interventional clinical trials:

(show top 50) (show all 1360)
# Name Status NCT ID Phase Drugs
1 Transcranial Magnetic Stimulation for Post-Traumatic Stress Disorder Unknown status NCT00134446 Phase 4
2 Prevention of Posttraumatic Stress Disorder (PTSD) With Diazepam Unknown status NCT01221883 Phase 4 Diazepam
3 Tramadol Extended-Release (ER) for Posttraumatic Stress Disorder (PTSD) Unknown status NCT01517711 Phase 4 Tramadol;Placebo
4 Add on Study on Δ9-THC Treatment for Posttraumatic Stress Disorders (PTSD) Unknown status NCT00965809 Phase 4 Tetrahydrocannabinol
5 The Effect of 21-Days Intranasal Oxytocin on Patients With Post Traumatic Stress Disorder (PTSD) Unknown status NCT02336568 Phase 4 Oxytoine;PLACEBO
6 Predictors of Treatment Response to Fluoxetine in PTSD Following a Recent History of War Zone Stress Exposure Unknown status NCT00633685 Phase 4 Fluoxetine;Placebo
7 A Randomized Cross Over Trial of Two Treatments for Obstructive Sleep Apnea in Veterans With Post Traumatic Stress Disorder Unknown status NCT01535586 Phase 4
8 Management of Chronic Pain in Military Patients With Injuries Sustained During Active Duty Unknown status NCT01616342 Phase 4
9 An Open Label Pilot Study of Adjunctive Asenapine for the Treatment of Posttraumatic Stress Disorder Completed NCT01587118 Phase 4 Adjunctive asenapine
10 Effect of Propranolol on Preventing Posttraumatic Stress Disorder Completed NCT00158262 Phase 4 Propranolol;Placebo
11 Cognitive Behavioral Therapy Versus Sertraline in the Treatment of Post-Traumatic Stress Disorder Completed NCT00391430 Phase 4 Sertraline
12 Eszopiclone for the Treatment of Posttraumatic Stress Disorder Completed NCT01605253 Phase 4 Eszopiclone;Placebo
13 Treatment for Alcoholism and Post-Traumatic Stress Disorder (Naltrexone) Completed NCT00006489 Phase 4 Naltrexone;Placebo
14 PROlonGed ExpoSure Sertraline Completed NCT01524133 Phase 4 Sertraline
15 Placebo Controled Clinical Trial Using Topiramate To Treat Posttraumatic Stress Disorder (PTSD) Patients. Completed NCT00725920 Phase 4 Topiramate;placebo control group
16 Eszopiclone for Sleep Disturbance and Nightmares in Post-Traumatic Stress Disorder Completed NCT00120250 Phase 4 Eszopiclone
17 Clonazepam and Paroxetine for Rapid Treatment of Post-Traumatic Stress Disorder Completed NCT00025740 Phase 4 clonazepam and paroxetine
18 Developing Memory Reconsolidation Blockers as Novel Posttraumatic Stress Disorder (PTSD) Treatments Completed NCT01490697 Phase 4 Mifepristone;d-Cycloserine;Placebo-matching Mifepristone;Placebo-matching d-Cycloserine (DCS)
19 Combined Mirtazapine and SSRI Treatment of PTSD: A Placebo-Controlled Trial Completed NCT01178671 Phase 4 Mirtazapine;Sertraline
20 Geodon (Ziprasidone) for Posttraumatic Stress Disorder Completed NCT00208208 Phase 4 Ziprasidone
21 Topiramate in the Treatment of Posttraumatic Stress Disorder in Civilians Completed NCT00208130 Phase 4 Topiramate
22 Secondary Prevention With Paroxetine vs. Placebo in Subthreshold Posttraumatic Stress Disorder (PTSD) Completed NCT00560612 Phase 4 Paroxetine;Placebo
23 Brain Markers of Treatment Response in Post-Traumatic Stress Disorder (PTSD) Completed NCT00700999 Phase 4 Paroxetine
24 Vilazodone for the Treatment of Posttraumatic Stress Disorder Completed NCT01715519 Phase 4 Treatment (Viibryd)
25 Neural Circuits in Women With Abuse and Posttraumatic Stress Disorder Completed NCT01681849 Phase 4 Placebo;Paroxetine
26 Topiramate Treatment of Alcohol Use Disorders in Veterans With Post Traumatic Stress Disorder (PTSD): A Pilot Controlled Trial of Augmentation Therapy Completed NCT01087736 Phase 4 Topiramate
27 Effects of Paxil CR on Neural Circuits in Posttraumatic Stress Disorder (PTSD) Completed NCT00672776 Phase 4 paroxetine;placebo
28 Topiramate in the Treatment of Post Traumatic Stress Disorder (PTSD) Completed NCT00203463 Phase 4 topiramate
29 A Psychophysiologic Study of Weakening Traumatic Combat Memories With Post-Reactivation Propranolol Completed NCT00709735 Phase 4 Propranolol;Placebo
30 Combination Treatment for Posttraumatic Stress Disorder (PTSD) After the World Trade Center (WTC) Attack Completed NCT01130103 Phase 4 Paroxetine
31 The Effect of Intranasal Oxytocin on Emphatic Abilities in Patients With Post Traumatic Stress Disorder (PTSD) Completed NCT01325168 Phase 4 syntocinon nasal spray;placebo nasal spray
32 An Open-Label Trial of Memantine for Cognitive Impairment in Patients With Post-Traumatic Stress Disorder Completed NCT02258828 Phase 4 Memantine
33 Effects of Escitalopram on Autonomic Reactivity in Post Traumatic Stress Disorder Completed NCT01271244 Phase 4 Escitalopram
34 A Study of Sertraline to Prevent PTSD Completed NCT00182078 Phase 4 Placebo;Sertraline
35 Serotonin Selective Reuptake Inhibitor Treatment of Dual Diagnosis Post-traumatic Stress Disorder and Alcohol Problems Completed NCT02504931 Phase 4 Sertraline;Placebo
36 The Outcome of Treatment of Traumatised Refugees With Psychotherapy and/or Antidepressants Completed NCT00917397 Phase 4 Sertraline
37 Risperidone in the Treatment of PTSD in Women Survivors of Domestic Abuse and Rape Trauma Completed NCT00208182 Phase 4 Risperidone
38 Telemedicine Outreach for Post Traumatic Stress in CBOCs Completed NCT00821678 Phase 4
39 Veteran Stress and Learning Study Completed NCT00674570 Phase 4 Hydrocortisone;D-Cycloserine;Placebo
40 Quetiapine Treatment for Post-Traumatic Stress Disorder (PTSD) Completed NCT00237393 Phase 4 Quetiapine;Placebo
41 The Treatment of Traumatised Refugees With Sertraline Versus Venlafaxine in Combination With Psychotherapy Completed NCT01569685 Phase 4 Venlafaxine;Sertraline
42 A Placebo-Controlled Study of Mirtazapine for PTSD Completed NCT00302107 Phase 4 Mirtazapine;Placebo
43 Evaluation of Stress Disorders Completed NCT00050804 Phase 4 sertraline
44 Veterans Individual Placement and Support Towards Advancing Recovery Completed NCT01817712 Phase 4
45 Primary Care Intervention Strategy for Anxiety Disorders Completed NCT00347269 Phase 4 Psychotropic medication optimization
46 Prazosin Treatment for Combat Trauma PTSD (Post-Traumatic Stress Disorder) Nightmares and Sleep Disturbance Completed NCT00108420 Phase 4 Prazosin
47 Pilot Study of Pharmaceutical and Behavioral Interventions to Treat Anxiety Disorders Completed NCT01631682 Phase 4 Propranolol;Mifepristone;Intranasal oxytocin
48 Influence of Hydrocortisone on Immunologic Markers and Health Care Related Quality of Life in Patients After Cardiac Surgery Completed NCT00490828 Phase 4 Hydrocortisone
49 Cardiopulmonary Resuscitation Witnessing by a Relative Completed NCT01009606 Phase 4
50 Prazosin Alcohol Dependence IVR Study Completed NCT00167687 Phase 4 prazosin

Search NIH Clinical Center for Post-Traumatic Stress Disorder

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: stress disorders, post-traumatic

Genetic Tests for Post-Traumatic Stress Disorder

Genetic tests related to Post-Traumatic Stress Disorder:

# Genetic test Affiliating Genes
1 Post-Traumatic Stress Disorder 29

Anatomical Context for Post-Traumatic Stress Disorder

MalaCards organs/tissues related to Post-Traumatic Stress Disorder:

41
Brain, Heart, Eye, Testes, Cortex, Amygdala, Lung

Publications for Post-Traumatic Stress Disorder

Articles related to Post-Traumatic Stress Disorder:

(show top 50) (show all 763)
# Title Authors Year
1
Severe and protracted sleep disruptions in mouse model of post-traumatic stress disorder. ( 29346627 )
2018
2
The long-term impact of post traumatic stress disorder on recovery from heroin dependence. ( 29706174 )
2018
3
A Systematic Review of Interleukin-1I^ in Post-Traumatic Stress Disorder: Evidence from Human and Animal Studies. ( 29328883 )
2018
4
The Use of Eye-Movement Desensitization Reprocessing (EMDR) Therapy in Treating Post-traumatic Stress Disorder-A Systematic Narrative Review. ( 29928250 )
2018
5
Emergency room intervention to prevent post concussion-like symptoms and post-traumatic stress disorder. A pilot randomized controlled study of a brief eye movement desensitization and reprocessing intervention versus reassurance or usual care. ( 29894921 )
2018
6
DBS in Treatment of Post-Traumatic Stress Disorder. ( 29361705 )
2018
7
The role of negative cognitions, emotion regulation strategies, and attachment style in complex post-traumatic stress disorder: Implications for new and existing therapies. ( 29355986 )
2018
8
The Transcendental Meditation Program's Impact on the Symptoms of Post-traumatic Stress Disorder of Veterans: An Uncontrolled Pilot Study. ( 29401353 )
2018
9
When Post-Traumatic Stress Disorder and Charles Bonnet Syndrome Become Lewy Body Dementia. ( 29778582 )
2018
10
Military-Tailored Yoga for Veterans with Post-traumatic Stress Disorder. ( 29415222 )
2018
11
Psychological interventions for post-traumatic stress disorder in refugees and asylum seekers: A systematic review and meta-analysis. ( 29936342 )
2018
12
Associations of trauma exposure and post-traumatic stress disorder with the activity of the renin-angiotensin-aldosterone-system in the general population. ( 29909779 )
2018
13
Application of data pooling to longitudinal studies of early post-traumatic stress disorder (PTSD): the International Consortium to Predict PTSD (ICPP) project. ( 29938009 )
2018
14
Comorbid insomnia and sleep apnea in Veterans with post-traumatic stress disorder. ( 29330769 )
2018
15
Multimodal Treatment With ECT for Identity Integration in a Patient With Dissociative Identity Disorder, Complex Post-traumatic Stress Disorder, and Major Depressive Disorder: A Rare Case Report. ( 29977211 )
2018
16
Regulation of threat in post-traumatic stress disorder: Associations between inhibitory control and dissociative symptoms. ( 29409740 )
2018
17
Longitudinal trajectories of post-traumatic stress disorder (PTSD) after birth and associated risk factors. ( 29331697 )
2018
18
Cotinine: A Therapy for Memory Extinction in Post-traumatic Stress Disorder. ( 29335846 )
2018
19
Trial of Prazosin for Post-Traumatic Stress Disorder in Military Veterans. ( 29414272 )
2018
20
trans-Resveratrol ameliorates anxiety-like behaviors and fear memory deficits in a rat model of post-traumatic stress disorder. ( 29373817 )
2018
21
Depression, Anxiety, Post-traumatic Stress Disorder and a History of Pervasive Gender-Based Violence Among Women Asylum Seekers Who Have Undergone Female Genital Mutilation/Cutting: A Retrospective Case Review. ( 29968003 )
2018
22
From post-traumatic stress disorder to absolute dependence in an intensive care unit: reflections on a clinical account. ( 29925572 )
2018
23
Acquired Stuttering in Veterans of the Wars in Iraq and Afghanistan: The Role of Traumatic Brain Injury, Post-Traumatic Stress Disorder, and Medications. ( 29912436 )
2018
24
Augmenting inpatient treatment for post-traumatic stress disorder with a computerised cognitive bias modification procedure targeting appraisals (CBM-App): protocol for a randomised controlled trial. ( 29961004 )
2018
25
A review on inflammatory cytokine-induced alterations of the brain as potential neural biomarkers in post-traumatic stress disorder. ( 29932946 )
2018
26
Melatonin ameliorates cognitive memory by regulation of cAMP-response element-binding protein expression and the anti-inflammatory response in a rat model of post-traumatic stress disorder. ( 29973144 )
2018
27
Smaller hippocampal volume following sexual assault in women is associated with post-traumatic stress disorder. ( 29952088 )
2018
28
Undetected post-traumatic stress disorder in secondary-care mental health services: systematic review. ( 29433609 )
2018
29
Post-Traumatic Stress Disorder Delineating the Progression and Underlying Mechanisms Following Blast Traumatic Brain Injury. ( 29888766 )
2018
30
Cortical surface area reduction in identification of subjects at high risk for post-traumatic stress disorder: A pilot study. ( 29361837 )
2018
31
Veterans' Perspectives on Fitbit Use in Treatment for Post-Traumatic Stress Disorder: An Interview Study. ( 29907556 )
2018
32
Influence of adjuvant mindfulness-based cognitive therapy (MBCT) on symptoms of post-traumatic stress disorder (PTSD) in veterans - results from a randomized control study. ( 29893182 )
2018
33
Effect of Post-Traumatic Stress Disorder on Cognitive Function and Covert Hepatic Encephalopathy Diagnosis in Cirrhotic Veterans. ( 29313245 )
2018
34
Intermittent hypoxia improves behavioral and adrenal gland dysfunction induced by post-traumatic stress disorder in rats. ( 29927732 )
2018
35
Familial risk for psychiatric disorders in military veterans who have post-traumatic stress disorder with psychosis: a retrospective electronic record review. ( 29384891 )
2018
36
To lose an unborn child: Post-traumatic stress disorder and major depressive disorder following pregnancy loss among Israeli women. ( 29934032 )
2018
37
Influence of early stress on memory reconsolidation: Implications for post-traumatic stress disorder treatment. ( 29352277 )
2018
38
Interaction between early-life stress and FKBP5 gene variants in major depressive disorder and post-traumatic stress disorder: A systematic review and meta-analysis. ( 28850857 )
2018
39
Prison employment and post-traumatic stress disorder: Risk and protective factors. ( 29896918 )
2018
40
The Effectiveness of Using Neurofeedback in the Treatment of Post-Traumatic Stress Disorder: A Systematic Review. ( 29890906 )
2018
41
Animal-Assisted Therapy for Post-traumatic Stress Disorder: Lessons from "Case Reports" in Media Stories. ( 29401355 )
2018
42
Tensor decomposition-based unsupervised feature extraction identifies candidate genes that induce post-traumatic stress disorder-mediated heart diseases. ( 29322921 )
2017
43
Risk of relapse after antidepressant discontinuation in anxiety disorders, obsessive-compulsive disorder, and post-traumatic stress disorder: systematic review and meta-analysis of relapse prevention trials. ( 28903922 )
2017
44
Mind-Body Therapy for Military Veterans with Post-Traumatic Stress Disorder: A Systematic Review. ( 28880607 )
2017
45
The MCP-4/MCP-1 ratio in plasma is a candidate circadian biomarker for chronic post-traumatic stress disorder. ( 28170001 )
2017
46
Comorbidity of post-traumatic stress disorder and anxiety in flood survivors: Prevalence and shared risk factors. ( 28885358 )
2017
47
A Pilot Study of the Effects of Mindfulness-Based Stress Reduction on Post-traumatic Stress Disorder Symptoms and Brain Response to Traumatic Reminders of Combat in Operation Enduring Freedom/Operation Iraqi Freedom Combat Veterans with Post-traumatic Stress Disorder. ( 28890702 )
2017
48
Decreased plasma adiponectin among male firefighters with symptoms of post-traumatic stress disorder. ( 28662456 )
2017
49
Self-esteem and hope mediate the relations between social support and post-traumatic stress disorder and growth in adolescents following the Ya'an earthquake. ( 28882068 )
2017
50
Depression and post-traumatic stress disorder in individuals with hereditary hemorrhagic telangiectasia: A cross-sectional survey. ( 28314138 )
2017

Variations for Post-Traumatic Stress Disorder

Expression for Post-Traumatic Stress Disorder

Search GEO for disease gene expression data for Post-Traumatic Stress Disorder.

Pathways for Post-Traumatic Stress Disorder

Pathways related to Post-Traumatic Stress Disorder according to GeneCards Suite gene sharing:

(show all 12)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.8 ADCYAP1R1 COMT DRD2 FKBP5 MAOA MAOB
2
Show member pathways
11.77 BDNF DRD2 MAOA MAOB
3 11.72 HTR2A MAOA MAOB SLC6A4
4
Show member pathways
11.53 COMT MAOA MAOB
5 11.44 ADCYAP1 ADCYAP1R1 BDNF HTR2A IL1B MAOA
6
Show member pathways
11.24 IL1B MAOA SLC6A4
7 10.94 HTR2A MAOA SLC6A4
8
Show member pathways
10.85 COMT MAOA SLC6A4
9
Show member pathways
10.62 MAOA MAOB
10
Show member pathways
10.54 ADCYAP1 ADCYAP1R1
11
Show member pathways
10.51 COMT MAOA MAOB
12 10.28 COMT MAOA MAOB

GO Terms for Post-Traumatic Stress Disorder

Cellular components related to Post-Traumatic Stress Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 axon GO:0030424 9.02 BDNF CNR1 COMT DRD2 HTR2A

Biological processes related to Post-Traumatic Stress Disorder according to GeneCards Suite gene sharing:

(show all 23)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.88 ADCYAP1 CRH CRP IL1B SLC6A4
2 response to lipopolysaccharide GO:0032496 9.81 CNR1 COMT IL1B MAOB
3 response to toxic substance GO:0009636 9.78 DRD2 MAOB SLC6A4
4 female pregnancy GO:0007565 9.75 ADCYAP1 COMT CRH
5 negative regulation of cell death GO:0060548 9.71 ADCYAP1R1 CRH DRD2
6 sensory perception of pain GO:0019233 9.67 ADCYAP1 CNR1 HTR2A
7 memory GO:0007613 9.67 BDNF CNR1 HTR2A SLC6A4
8 synaptic transmission, dopaminergic GO:0001963 9.61 CRH DRD2
9 response to cocaine GO:0042220 9.61 CNR1 CRH DRD2
10 negative regulation of synaptic transmission, glutamatergic GO:0051967 9.6 DRD2 HTR2A
11 response to corticosterone GO:0051412 9.59 CRH MAOB
12 dopamine metabolic process GO:0042417 9.58 COMT DRD2
13 regulation of synaptic transmission, GABAergic GO:0032228 9.57 CNR1 DRD2
14 catecholamine metabolic process GO:0006584 9.56 COMT MAOA
15 negative regulation of potassium ion transport GO:0043267 9.55 ADCYAP1 HTR2A
16 positive regulation of growth hormone secretion GO:0060124 9.52 ADCYAP1 DRD2
17 positive regulation of cAMP-mediated signaling GO:0043950 9.5 ADCYAP1 ADCYAP1R1 CRH
18 response to drug GO:0042493 9.5 ADCYAP1R1 COMT CRH DRD2 HTR2A MAOB
19 positive regulation of fever generation GO:0031622 9.46 CNR1 IL1B
20 neurotransmitter catabolic process GO:0042135 9.43 COMT MAOA MAOB
21 negative regulation of dopamine secretion GO:0033602 9.4 CNR1 DRD2
22 dopamine catabolic process GO:0042420 9.33 COMT MAOA MAOB
23 response to ethanol GO:0045471 9.1 ADCYAP1 ADCYAP1R1 CNR1 CRH DRD2 MAOB

Molecular functions related to Post-Traumatic Stress Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 drug binding GO:0008144 9.13 CNR1 DRD2 HTR2A
2 primary amine oxidase activity GO:0008131 8.62 MAOA MAOB

Sources for Post-Traumatic Stress Disorder

3 CDC
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