MCID: PST007
MIFTS: 24

Post-Vaccinal Encephalitis

Categories: Immune diseases, Neuronal diseases
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Aliases & Classifications for Post-Vaccinal Encephalitis

MalaCards integrated aliases for Post-Vaccinal Encephalitis:

Name: Post-Vaccinal Encephalitis 11 14 71
Encephalitis Following Immunization Procedures 11
Encephalomyelitis, Acute Disseminated 43
Postvaccinal Encephalomyelitis 11

Classifications:



External Ids:

Disease Ontology 11 DOID:13664
MeSH 43 D004673
SNOMED-CT 68 31367003
UMLS 71 C0751101

Summaries for Post-Vaccinal Encephalitis

MalaCards based summary: Post-Vaccinal Encephalitis, also known as encephalitis following immunization procedures, is related to acute disseminated encephalomyelitis and viral encephalitis. An important gene associated with Post-Vaccinal Encephalitis is CCR6 (C-C Motif Chemokine Receptor 6). The drugs Vaccines and Antibodies, Blocking have been mentioned in the context of this disorder. Affiliated tissues include brain, lung and skin.

Related Diseases for Post-Vaccinal Encephalitis

Diseases related to Post-Vaccinal Encephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 39)
# Related Disease Score Top Affiliating Genes
1 acute disseminated encephalomyelitis 32.4 MBP CCR6
2 viral encephalitis 30.2 MBP CCR6
3 encephalitis 10.9
4 smallpox 10.4
5 progressive relapsing multiple sclerosis 10.2 MBP CCR6
6 transverse myelitis 10.1 MBP CCR6
7 myelitis 10.1 MBP CCR6
8 progressive multifocal leukoencephalopathy 10.1 MBP CCR6
9 autoimmune disease of peripheral nervous system 10.1 MBP CCR6
10 west nile encephalitis 10.1 MBP CCR6
11 choroiditis 10.1 HTRA1 CCR6
12 primary progressive multiple sclerosis 10.1 MBP CCR6
13 creutzfeldt-jakob disease 10.1
14 kuru 10.1
15 central diabetes insipidus 10.1
16 rabies 10.1
17 megacolon 10.1
18 vaccinia 10.1
19 brain edema 10.1
20 scrapie 10.1
21 prion disease 10.1
22 diabetes insipidus 10.1
23 encephalopathy 10.1
24 meningoencephalitis 10.0 MBP CCR6
25 tick-borne encephalitis 10.0
26 postinfectious encephalitis 10.0
27 movement disease 10.0
28 secondary progressive multiple sclerosis 10.0 MBP CCR6
29 autoimmune polyendocrine syndrome, type ii 9.9 POMC CCR6
30 opioid abuse 9.9 POMC CCR6
31 adrenal cortical hypofunction 9.9 POMC CCR6
32 arachnoiditis 9.9 POMC MBP
33 central pontine myelinolysis 9.9 POMC MBP
34 sebaceous gland disease 9.9 POMC CCR6
35 hypoadrenocorticism, familial 9.8 POMC CCR6
36 adrenal cortex disease 9.8 POMC CCR6
37 cranial nerve disease 9.8 POMC MBP CCR6
38 adrenal gland disease 9.7 POMC CCR6
39 hair disease 9.6 POMC CCR6

Graphical network of the top 20 diseases related to Post-Vaccinal Encephalitis:



Diseases related to Post-Vaccinal Encephalitis

Symptoms & Phenotypes for Post-Vaccinal Encephalitis

Drugs & Therapeutics for Post-Vaccinal Encephalitis

Drugs for Post-Vaccinal Encephalitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 14)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Vaccines Phase 4
2 Antibodies, Blocking Phase 4
3
Prednisolone phosphate Approved, Vet_approved Phase 3 302-25-0
4
Prednisolone acetate Approved, Vet_approved Phase 3 52-21-1
5
Prednisolone Approved, Vet_approved Phase 3 50-24-8 4894 5755
6
Methylprednisolone hemisuccinate Approved Phase 3 2921-57-5 1875
7
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 4159 6741
8
Prednisolone hemisuccinate Experimental Phase 3 2920-86-7 4897
9
Methylprednisolone Acetate Phase 3 584547
10 Immunoglobulins
11 Antibodies
12 Immunologic Factors
13 Immunoglobulins, Intravenous
14 Immunosuppressive Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Neutralizing Antibody Titers 6 Years After the Third Dose of Inactivated Japanese Encephalitis Vaccine and Projected Duration of Protection Completed NCT02039440 Phase 4
2 Phase III Randomized, Double-Blind, Sham-Controlled Study of Plasma Exchange for Acute Severe Attacks of Inflammatory Demyelinating Disease Refractory to Intravenous Methylprednisolone Unknown status NCT00004645 Phase 3
3 Management of Acute Disseminated Encephalomyelitis in Neurology Unit of Assiut University Children Hospital Unknown status NCT03284801
4 China National Registry of Central Nervous System Inflammatory Demyelinating Diseases: a Prospective Cohort Study Recruiting NCT05154370 Intravenous steroid
5 PEDIATRIC SONICS: Pediatric Study of Neuropsychology and Imaging in CNS Demyelinating Syndromes. Recruiting NCT03942952
6 Swiss Pediatric Inflammatory Bain Disease Cohort Study Recruiting NCT05017142
7 Large-scale, Multi-disciplinary Sample and Data Repository for Multiple Sclerosis and Related Demyelinating Diseases Active, not recruiting NCT00445367

Search NIH Clinical Center for Post-Vaccinal Encephalitis

Cochrane evidence based reviews: encephalomyelitis, acute disseminated

Genetic Tests for Post-Vaccinal Encephalitis

Anatomical Context for Post-Vaccinal Encephalitis

Organs/tissues related to Post-Vaccinal Encephalitis:

MalaCards : Brain, Lung, Skin

Publications for Post-Vaccinal Encephalitis

Articles related to Post-Vaccinal Encephalitis:

(show top 50) (show all 86)
# Title Authors PMID Year
1
Neurologic Complications of Smallpox and Monkeypox: A Review. 62
36125794 2022
2
Post-Vaccinal Encephalitis with Early Relapse after BNT162b2 (COMIRNATY) COVID-19 Vaccine: A Case Report. 62
35891229 2022
3
Central nervous system adverse events after ChAdOx1 vaccination. 62
35275317 2022
4
Immunogenicity and safety of concurrent or sequential administration of live, attenuated SA 14-14-2 Japanese encephalitis vaccine (CD-JEV) and measles-mumps-rubella vaccine in infants 9-12 months of age in the Philippines: A non-inferiority Phase 4 randomized clinical trial. 62
33005887 2020
5
Reversible postvaccination paraneoplastic encephalomyelitis in a patient with lung adenocarcinoma. 62
20964557 2010
6
A mouse-based assay for the pre-clinical neurovirulence assessment of vaccinia virus-based smallpox vaccines. 62
19896867 2010
7
Iatrogenic concerns of the twentieth century: post-vaccinal encephalitis and spongiform encephalopathy. 62
21553697 2010
8
The origin and application of experimental autoimmune encephalomyelitis. 62
17917672 2007
9
Anticipating smallpox and monkeypox outbreaks: complications of the smallpox vaccine. 62
15335444 2004
10
Smallpox and smallpox vaccination: neurological implications. 62
12707424 2003
11
Encephalomyelitis, brain tumors, neuromuscular diseases and miscellaneous disorders. 62
11037180 2000
12
DNA vaccine encoding nucleocapsid and surface proteins of wild type canine distemper virus protects its natural host against distemper. 62
10825593 2000
13
ADEM: literature review and case report of acute psychosis presentation. 62
10669199 2000
14
[Acute disseminated encephalomyelitis]. 62
9103897 1997
15
[Guillain-Barré syndrome and acute disseminated encephalomyelitis (ADEM)]. 62
9128388 1996
16
Fatal rabies associated with extensive demyelination. 62
8442714 1993
17
Semple rabies vaccine: presence of myelin basic protein and proteolipid protein and its activity in experimental allergic encephalomyelitis. 62
2480399 1989
18
Rapid diagnosis of rabies and post-vaccinal encephalitides. 62
2894908 1988
19
Schilder's myelinoclastic diffuse sclerosis. 62
3940347 1986
20
[A highly efficient, highly purified duck embryo rabies vaccine]. 62
4089577 1985
21
Comparative analysis of the degree of specific humoral immunity, content of serum immunoglobulins and isolation of vaccinia virus in children with post-vaccinal encephalitis after smallpox vaccination. 62
6117594 1981
22
Allergic encephalitis, rabies antibodies, and the blood/brain barrier. 62
38289 1979
23
Postvaccinal encephalomyelitis without cutaneous vaccination reaction. 62
34358 1979
24
[Postvaccinal encephalitis in adult. A case with anatomo-clinical report (author's transl)]. 62
45321 1979
25
[Cases of postvaccinal encephalomyelitis after inoculation against tick-borne encephalitis]. 62
633817 1978
26
Post-vaccinal encephalitis. 62
24200 1977
27
The clinical picture of rabies in man. 62
982512 1976
28
Post-vaccinal encephalitis. Report of a case. 62
6390 1975
29
[Histopathological changes in patients with post-vaccinal encephalitis]. 62
54940 1975
30
[Pathomorphological and immunofluorescent studies of smallpox vaccine neurotropism]. 62
239507 1975
31
[Postvacccinal encephalomyelitis after protective antirabic innoculation, combined with polioencephalomyelitis (lyssa?)]. 62
702 1975
32
[On therapy of post-vaccinal encephalitis]. 62
4154396 1974
33
A virological study of post-vaccinal encephalitis. 62
4150692 1974
34
Skin reactivity and antibody response following vaccination against smallpox. 62
4150693 1974
35
[Manifestation of juvenile diabetes mellitus following postvaccinal encephalomyelitis]. 62
4150477 1973
36
[Diabetes mellitus from post-vaccinal encephalitis?]. 62
4392770 1970
37
[Post-vaccinal encephalitis in an infant with latent herpes infection]. 62
4395307 1970
38
[Contribution to the problem of allergic brain edema after variolation imitating post-vaccinal encephalitis]. 62
4390264 1969
39
[Recent views on the pathogenesis of parainfectious and post-vaccinal encephalitis]. 62
4389986 1969
40
[Contribution on the problem of allergic cerebral edema, following smallpox vaccination, that imitates post-vaccinal encephalitis]. 62
4389294 1968
41
[Favorable course of severe post-vaccinal encephalitis under supporting therapy with helfergin (centrophenoxine)]. 62
4388772 1968
42
[Rabies: prophylaxis and treatment. Apropos of a case of postvaccinal encephalomyelitis]. 62
4394863 1968
43
[Does an "asthenic" vaccination reaction lead to post-vaccinal encephalitis?]. 62
4386941 1968
44
[On the effectiveness of gamma-globulin with increased antivariolous antibody content in the treatment of post-vaccinal encephalitis]. 62
4176769 1968
45
[On the problem of postvaccinal encephalomyelitis with particular consideration of central nervous system complications after smallpox vaccination]. 62
4382466 1966
46
[Post-vaccinal encephalitis: a virologic study]. 62
4380154 1966
47
[Post-vaccinal encephalitis]. 62
4380994 1966
48
[Smallpox vaccinations and post-vaccinal encephalitis]. 62
4378496 1965
49
[Post-vaccinal encephalitis]. 62
4378642 1964
50
[Post-vaccinal encephalitis and its prophylaxis from the pediatrician's viewpoint]. 62
4157624 1964

Variations for Post-Vaccinal Encephalitis

Expression for Post-Vaccinal Encephalitis

Search GEO for disease gene expression data for Post-Vaccinal Encephalitis.

Pathways for Post-Vaccinal Encephalitis

GO Terms for Post-Vaccinal Encephalitis

Sources for Post-Vaccinal Encephalitis

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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