MCID: PST018
MIFTS: 34

Posterior Cerebral Artery Infarction

Categories: Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Posterior Cerebral Artery Infarction

MalaCards integrated aliases for Posterior Cerebral Artery Infarction:

Name: Posterior Cerebral Artery Infarction 12 15 17
Infarction, Posterior Cerebral Artery 44 70

Classifications:



External Ids:

Disease Ontology 12 DOID:3821
MeSH 44 D020762
UMLS 70 C0752132

Summaries for Posterior Cerebral Artery Infarction

MalaCards based summary : Posterior Cerebral Artery Infarction, also known as infarction, posterior cerebral artery, is related to middle cerebral artery infarction and moyamoya disease 1. An important gene associated with Posterior Cerebral Artery Infarction is P2RX3 (Purinergic Receptor P2X 3), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Selenium Micronutrient Network. The drugs Epinephrine and Racepinephrine have been mentioned in the context of this disorder. Affiliated tissues include heart, placenta and cortex, and related phenotypes are cardiovascular system and integument

Related Diseases for Posterior Cerebral Artery Infarction

Diseases in the Anterior Cerebral Artery Infarction family:

Posterior Cerebral Artery Infarction

Diseases related to Posterior Cerebral Artery Infarction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 172)
# Related Disease Score Top Affiliating Genes
1 middle cerebral artery infarction 29.9 PLG PLAT
2 moyamoya disease 1 29.2 PLG PLAT F3 F2
3 chronic pain 10.2 P2RX4 P2RX3
4 aphasia 10.2
5 medulloadrenal hyperfunction 10.2 PLG F3
6 retinal artery occlusion 10.2 PLG F2
7 leech infestation 10.1 PLG F3
8 anteroseptal myocardial infarction 10.1 PLG MB
9 anterior spinal artery syndrome 10.1 PLG F2
10 thoracic outlet syndrome 10.1 PLG F2
11 livedoid vasculitis 10.1 PLG F2
12 achenbach syndrome 10.1 F3 F2
13 kidney cortex necrosis 10.1 PLG F2
14 renal pelvis squamous cell carcinoma 10.1 F3 F2
15 cholesterol embolism 10.1 PLG F2
16 synovial angioma 10.1 F3 F2
17 papillary adenofibroma 10.1 F3 F2
18 emphysematous cholecystitis 10.1 F3 F2
19 giant hemangioma 10.1 F3 F2
20 hemopneumothorax 10.1 F3 F2
21 ceftriaxone allergy 10.1 MB F3
22 dic in newborn 10.1 F3 F2
23 ankylosing spondylitis 1 10.1 F3 F2
24 waterhouse-friderichsen syndrome 10.1 F3 F2
25 pulmonary embolism and infarction 10.1 F3 F2
26 cavernous sinus thrombosis 10.1 F3 F2
27 epidural abscess 10.1 F3 F2
28 lemierre's syndrome 10.1 F3 F2
29 gastric hemangioma 10.1 F3 F2
30 hepatic infarction 10.1 F3 F2
31 qualitative platelet defect 10.1 F3 F2
32 mediastinitis 10.1 F3 F2
33 pleural empyema 10.1 PLG F2
34 cerebral sinovenous thrombosis 10.1 F3 F2
35 prothrombin deficiency 10.1 F3 F2
36 intracranial hypotension 10.1 F3 F2
37 acquired von willebrand syndrome 10.1 F3 F2
38 active peptic ulcer disease 10.1 F3 F2
39 hepatic coma 10.1 F3 F2
40 splenic sequestration 10.1 F3 F2
41 splenic infarction 10.1 F3 F2
42 acute hemorrhagic encephalitis 10.1 F3 F2
43 pituitary adenoma 5, multiple types 10.1 F3 F2
44 vitamin k deficiency bleeding 10.1 F3 F2
45 hantavirus pulmonary syndrome 10.1 F3 F2
46 analbuminemia 10.1 F3 F2
47 hemarthrosis 10.0 F3 F2
48 esophageal varix 10.0 F3 F2
49 cecal disease 10.0 F3 F2
50 papilledema 10.0 F3 F2

Graphical network of the top 20 diseases related to Posterior Cerebral Artery Infarction:



Diseases related to Posterior Cerebral Artery Infarction

Symptoms & Phenotypes for Posterior Cerebral Artery Infarction

MGI Mouse Phenotypes related to Posterior Cerebral Artery Infarction:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.91 F2 F3 MB MEST P2RX3 P2RX4
2 integument MP:0010771 9.63 F2 F3 P2RX3 PLAT PLG TH
3 muscle MP:0005369 9.43 F2 F3 MB MEST P2RX4 PLAT
4 respiratory system MP:0005388 9.17 F2 F3 MB P2RX3 PLAT PLG

Drugs & Therapeutics for Posterior Cerebral Artery Infarction

Drugs for Posterior Cerebral Artery Infarction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Epinephrine Approved, Vet_approved 51-43-4 5816
2
Racepinephrine Approved 329-65-7 838
3 Epinephryl borate

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Phase 2A, Prospective, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study to Evaluate the Safety of Intravenous Infusion of Human Placenta-Derived Cells (PDA001) for the Treatment of Adults Following Ischemic Stroke Terminated NCT01310114 Phase 2 Placebo
2 Biological Function of Dreaming - Declarative and Non-declarative Memory Consolidation and Sleep Quality in Dreaming and Non-dreaming Patients With PCA Infarction Recruiting NCT04749992

Search NIH Clinical Center for Posterior Cerebral Artery Infarction

Cochrane evidence based reviews: infarction, posterior cerebral artery

Genetic Tests for Posterior Cerebral Artery Infarction

Anatomical Context for Posterior Cerebral Artery Infarction

MalaCards organs/tissues related to Posterior Cerebral Artery Infarction:

40
Heart, Placenta, Cortex, Kidney, Brain, Pituitary

Publications for Posterior Cerebral Artery Infarction

Articles related to Posterior Cerebral Artery Infarction:

(show top 50) (show all 62)
# Title Authors PMID Year
1
The anatomy of spatial neglect after posterior cerebral artery stroke. 61
33543137 2020
2
Revascularization for Posterior Cerebral Artery Infarction in Decompensated Moyamoya Disease. 61
31720150 2019
3
Investigation of risk factors, topographic location and stroke mechanisms of unilateral isolated and posterior cerebral ARTERY thalamic infarcts. 61
31517457 2019
4
Recurrent transient heading disorientation heralding acute posterior cerebral artery (PCA) infarction. 61
33681769 2019
5
Structural connectivity in spatial attention network: reconstruction from left hemispatial neglect. 61
28290071 2018
6
Punding following posterior cerebral artery infarction: a case report and literature review. 61
28408832 2017
7
Petroclival Meningioma Accompanying Posterior Cerebral Artery Infarction. 61
26846762 2016
8
Erectile dysfunction (ED) after ischemic stroke: association between prevalence and site of lesion. 61
26374302 2015
9
The Clot Strikes Thrice: Case Report of a Patient with 3 Concurrent Embolic events. 61
27333833 2015
10
Susceptibility Vessel Sign for Intra-arterial Thrombus in Acute Posterior Cerebral Artery Infarction. 61
25906931 2015
11
Simultaneous loss of bilateral voluntary eyelid opening and sustained winking response following bilateral posterior cerebral artery infarction. 61
25932428 2015
12
Carotid Endarterectomy in a Patient with Posterior Cerebral Artery Infarction: Influence of Fetal Type PCA on Atypical Clinical Course. 61
26171263 2015
13
Lesion Location-Based Prediction of Visual Field Improvement after Cerebral Infarction. 61
26606516 2015
14
[Simultanagnosia and scene agnosia induced by right posterior cerebral artery infarction: a case report]. 61
26369377 2015
15
Distal embolic brain infarction due to recanalization of asymptomatic vertebral artery occlusion resulting from cervical spine injury: a case report. 61
25435840 2014
16
Embolic brain infarction related to posttraumatic occlusion of vertebral artery resulting from cervical spine injury: a case report. 61
25316102 2014
17
Delayed emergence from anesthesia resulting from posterior cerebral artery infarction after Guglielmi detachable coil embolization. 61
24478835 2013
18
Fluid-attenuated inversion recovery hyperintense vessels in posterior cerebral artery infarction. 61
24052794 2013
19
Reduced retinal ganglion cell complex thickness in patients with posterior cerebral artery infarction detected using spectral-domain optical coherence tomography. 61
22684619 2012
20
[Serious neurological sequelae of a myocarditis]. 61
22736181 2012
21
Posterior cerebral artery infarction: an understudied vascular topography of ischaemic stroke. 61
21418442 2011
22
Bilateral homonymous superior quadrantanopia after traumatic attempts to remove a cockroach impacted in the external auditory canal. 61
21495947 2011
23
Executive dysfunction associated with stroke in the posterior cerebral artery territory. 61
21167720 2011
24
Bilateral posterior cerebral artery infarction. 61
22798298 2010
25
Ipsilateral visual illusion after unilateral posterior cerebral artery infarction: a report of two cases. 61
20542522 2010
26
Isolated posterior cerebral artery infarction caused by carotid artery dissection. 61
19667228 2009
27
Splenium or parahippocampus involvement and its relationship to cognitive decline in posterior cerebral artery infarction. 61
19329320 2009
28
Right sensory alien hand phenomenon from a left pontine hemorrhage. 61
19513334 2009
29
Posterior cerebral artery infarction: diffusion-weighted MRI analysis of 205 patients. 61
19622882 2009
30
Magnetic resonance correlate of hemiparesis in posterior cerebral artery infarction. 61
18984431 2008
31
Neuroimaging in acute posterior cerebral artery infarction. 61
18469674 2008
32
Acute confusional state with posterior cerebral artery infarction: a challenge in the diagnosis of acute stroke at bedside. 61
17966950 2007
33
Malignant posterior cerebral artery infarction. 61
17219035 2006
34
Incidental detection of previously undiagnosed primary breast carcinoma with a gallium-67 scan performed for evaluation of occult infection. 61
17117084 2006
35
Visual neglect after right posterior cerebral artery infarction. 61
16772354 2006
36
Deafferentation-disconnection neglect induced by posterior cerebral artery infarction. 61
16401846 2006
37
Preserved complex emotion-based learning in amnesia. 61
16029879 2006
38
Posterior cerebral artery infarction from middle cerebral artery infarction. 61
15956164 2005
39
[Endovascular treatment of vertebral artery origin stenosis in high risk patients]. 61
15470631 2004
40
Agitated delirium with posterior cerebral artery infarction. 61
12676294 2003
41
Single stroke dementia: insights from 12 cases in Singapore. 61
12417363 2002
42
Sexual headache and stroke in a heavy cannabis smoker. 61
11903547 2002
43
Topiramate in venlafaxine-induced visual hallucinations in an obese patient with a posterior cerebral artery infarction. 61
11476137 2001
44
Posterior cerebral artery infarction caused by cerebral sparganosis-induced vasculitis. 61
11528164 2001
45
Electromyographic (EMG) biofeedback in the comprehensive treatment of central pain and ataxic tremor following thalamic stroke. 61
11218924 2000
46
Is decompressive craniectomy for acute cerebral infarction of any benefit? 61
10773253 2000
47
Differing mechanisms between posterior and middle cerebral artery infarctions. 61
17895092 1998
48
Posterior cerebral artery infarction associated with carotid dissection. 61
17895074 1998
49
Noninvasive assessment of posterior cerebral artery stenosis inducing hemiplegia. 61
9284595 1997
50
SPECT and MRI in posterior cerebral artery infarction and related visual field defects. 61
8509838 1993

Variations for Posterior Cerebral Artery Infarction

Expression for Posterior Cerebral Artery Infarction

Search GEO for disease gene expression data for Posterior Cerebral Artery Infarction.

Pathways for Posterior Cerebral Artery Infarction

GO Terms for Posterior Cerebral Artery Infarction

Cellular components related to Posterior Cerebral Artery Infarction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.73 PLG PLAT P2RX4 MEST MB F2
2 collagen-containing extracellular matrix GO:0062023 9.26 PLG PLAT F3 F2
3 integral component of nuclear inner membrane GO:0005639 9.16 P2RX4 P2RX3
4 terminal bouton GO:0043195 8.8 TH P2RX4 P2RX3

Biological processes related to Posterior Cerebral Artery Infarction according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 response to hypoxia GO:0001666 9.69 TH PLAT P2RX3
2 neuronal action potential GO:0019228 9.54 P2RX4 P2RX3
3 negative regulation of proteolysis GO:0045861 9.52 PLAT F2
4 response to ATP GO:0033198 9.49 P2RX4 P2RX3
5 cellular response to ATP GO:0071318 9.48 P2RX4 P2RX3
6 inorganic cation transmembrane transport GO:0098662 9.46 P2RX4 P2RX3
7 positive regulation of calcium-mediated signaling GO:0050850 9.43 P2RX4 P2RX3
8 positive regulation of calcium ion transport into cytosol GO:0010524 9.4 P2RX4 P2RX3
9 behavioral response to pain GO:0048266 9.37 P2RX4 P2RX3
10 hemostasis GO:0007599 9.33 PLG F3 F2
11 negative regulation of fibrinolysis GO:0051918 9.32 PLG F2
12 purinergic nucleotide receptor signaling pathway GO:0035590 9.26 P2RX4 P2RX3
13 fibrinolysis GO:0042730 9.13 PLG PLAT F2
14 blood coagulation GO:0007596 9.1 PLG PLAT P2RX4 P2RX3 F3 F2

Molecular functions related to Posterior Cerebral Artery Infarction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 9.56 PLG PLAT P2RX4 F2
2 serine-type peptidase activity GO:0008236 9.5 PLG PLAT F2
3 oxygen binding GO:0019825 9.37 TH MB
4 extracellularly ATP-gated cation channel activity GO:0004931 9.16 P2RX4 P2RX3
5 purinergic nucleotide receptor activity GO:0001614 8.96 P2RX4 P2RX3
6 serine-type endopeptidase activity GO:0004252 8.92 PLG PLAT F3 F2

Sources for Posterior Cerebral Artery Infarction

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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