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MCID: PST018
MIFTS: 31

Posterior Cerebral Artery Infarction

Categories: Cardiovascular diseases, Neuronal diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Posterior Cerebral Artery Infarction

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MalaCards integrated aliases for Posterior Cerebral Artery Infarction:

Name: Posterior Cerebral Artery Infarction 12 15 17
Infarction, Posterior Cerebral Artery 43 71

Classifications:

MalaCards categories:
Anatomical: Cardiovascular diseases Neuronal diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:3821
MeSH 43 D020762
UMLS 71 C0752132
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Summaries for Posterior Cerebral Artery Infarction

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MalaCards based summary : Posterior Cerebral Artery Infarction, also known as infarction, posterior cerebral artery, is related to aphasia and middle cerebral artery infarction. An important gene associated with Posterior Cerebral Artery Infarction is SLC26A5 (Solute Carrier Family 26 Member 5), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Formation of Fibrin Clot (Clotting Cascade). Affiliated tissues include brain, cortex and breast, and related phenotypes are cardiovascular system and hematopoietic system

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Related Diseases for Posterior Cerebral Artery Infarction

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Diseases in the Anterior Cerebral Artery Infarction family:

Posterior Cerebral Artery Infarction

Diseases related to Posterior Cerebral Artery Infarction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 103)
# Related Disease Score Top Affiliating Genes
1 aphasia 30.2 PLG PLAT MAPT
2 middle cerebral artery infarction 30.2 PLG PLAT
3 basilar artery insufficiency 10.4 TSPAN33 PLG
4 ligneous conjunctivitis 10.3 PLG PLAT
5 anterior cerebral artery infarction 10.3 PLG PLAT
6 basal ganglia cerebrovascular disease 10.3 PLG PLAT
7 thoracic outlet syndrome 10.3 PLG PLAT
8 vertebral artery occlusion 10.3 PLG PLAT
9 inferior myocardial infarction 10.3 PLG PLAT
10 conversion disorder 10.2 PLG PLAT
11 medulloadrenal hyperfunction 10.2 PLG F3
12 intracranial hypotension 10.2 SLC26A5 F3
13 hereditary angioedema with normal c1inh 10.2 PLG PLAT
14 basilar artery occlusion 10.2 TSPAN33 PLG PLAT
15 brain stem infarction 10.2 TSPAN33 PLG PLAT
16 carotid artery occlusion 10.2 TSPAN33 PLG PLAT
17 hemopericardium 10.2 PLG F3
18 agnosia 10.2
19 central retinal artery occlusion 10.2 PLG PLAT
20 anteroseptal myocardial infarction 10.2 PLG MB
21 leech infestation 10.2 PLG F3
22 acquired hemophilia 10.1 F9 F3
23 acquired hemophilia a 10.1 F9 F3
24 intracranial sinus thrombosis 10.1 TSPAN33 PLG F3
25 sagittal sinus thrombosis 10.1 TSPAN33 PLG F3
26 meningioma, radiation-induced 10.1
27 meningioma, familial 10.1
28 visual agnosia 10.1
29 hemiplegia 10.1
30 spinal meningioma 10.1
31 secretory meningioma 10.1
32 lymphoplasmacyte-rich meningioma 10.1
33 subacute delirium 10.1
34 prothrombin deficiency 10.1 F9 F3
35 adhesive otitis media 10.1 PLAT NKRF F9
36 alpha-2-plasmin inhibitor deficiency 10.0 PLG F3
37 acute cor pulmonale 10.0 PLG PLAT F3
38 acute pulmonary heart disease 10.0 PLG PLAT F3
39 marantic endocarditis 10.0 PLG PLAT F3
40 pica disease 10.0 MAPT DDX41
41 ceftriaxone allergy 10.0 MB F3
42 cerebral falx meningioma 10.0 PLG PLAT F3
43 post-thrombotic syndrome 10.0 PLG PLAT F3
44 intracranial thrombosis 10.0 PLG PLAT F3
45 acquired von willebrand syndrome 10.0 F9 F3
46 thrombophlebitis 10.0 PLG PLAT F3
47 central retinal vein occlusion 10.0 PLG PLAT F3
48 coronary thrombosis 10.0 PLG PLAT F3
49 carotid artery thrombosis 10.0 PLAT F3
50 pulmonary artery disease 10.0 PLG PLAT F3

Graphical network of the top 20 diseases related to Posterior Cerebral Artery Infarction:



Diseases related to Posterior Cerebral Artery Infarction
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Symptoms & Phenotypes for Posterior Cerebral Artery Infarction

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MGI Mouse Phenotypes related to Posterior Cerebral Artery Infarction:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.06 F3 F9 MAPT MB MEST MYPN
2 hematopoietic system MP:0005397 10 DDX41 F3 F9 MAPT MB P2RX4
3 immune system MP:0005387 9.85 DDX41 F3 F9 MAPT P2RX3 P2RX4
4 muscle MP:0005369 9.5 F3 MAPT MB MEST MYPN P2RX4
5 neoplasm MP:0002006 9.1 F3 MAPT PLG PSMB8 TH TSPAN33
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Drugs & Therapeutics for Posterior Cerebral Artery Infarction

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Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Phase 2A, Prospective, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study to Evaluate the Safety of Intravenous Infusion of Human Placenta-Derived Cells (PDA001) for the Treatment of Adults Following Ischemic Stroke Terminated NCT01310114 Phase 2 Placebo

Search NIH Clinical Center for Posterior Cerebral Artery Infarction

Cochrane evidence based reviews: infarction, posterior cerebral artery

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Genetic Tests for Posterior Cerebral Artery Infarction

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Anatomical Context for Posterior Cerebral Artery Infarction

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MalaCards organs/tissues related to Posterior Cerebral Artery Infarction:

40
Brain, Cortex, Breast
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Publications for Posterior Cerebral Artery Infarction

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Articles related to Posterior Cerebral Artery Infarction:

(show top 50) (show all 60)
# Title Authors PMID Year
1
Revascularization for Posterior Cerebral Artery Infarction in Decompensated Moyamoya Disease. 61
31720150 2019
2
Investigation of risk factors, topographic location and stroke mechanisms of unilateral isolated and posterior cerebral ARTERY thalamic infarcts. 61
31517457 2019
3
Structural connectivity in spatial attention network: reconstruction from left hemispatial neglect. 61
28290071 2018
4
Punding following posterior cerebral artery infarction: a case report and literature review. 61
28408832 2017
5
Petroclival Meningioma Accompanying Posterior Cerebral Artery Infarction. 61
26846762 2016
6
Erectile dysfunction (ED) after ischemic stroke: association between prevalence and site of lesion. 61
26374302 2015
7
The Clot Strikes Thrice: Case Report of a Patient with 3 Concurrent Embolic events. 61
27333833 2015
8
Susceptibility Vessel Sign for Intra-arterial Thrombus in Acute Posterior Cerebral Artery Infarction. 61
25906931 2015
9
Simultaneous loss of bilateral voluntary eyelid opening and sustained winking response following bilateral posterior cerebral artery infarction. 61
25932428 2015
10
Carotid Endarterectomy in a Patient with Posterior Cerebral Artery Infarction: Influence of Fetal Type PCA on Atypical Clinical Course. 61
26171263 2015
11
Lesion Location-Based Prediction of Visual Field Improvement after Cerebral Infarction. 61
26606516 2015
12
[Simultanagnosia and scene agnosia induced by right posterior cerebral artery infarction: a case report]. 61
26369377 2015
13
Distal embolic brain infarction due to recanalization of asymptomatic vertebral artery occlusion resulting from cervical spine injury: a case report. 61
25435840 2014
14
Embolic brain infarction related to posttraumatic occlusion of vertebral artery resulting from cervical spine injury: a case report. 61
25316102 2014
15
Delayed emergence from anesthesia resulting from posterior cerebral artery infarction after Guglielmi detachable coil embolization. 61
24478835 2013
16
Fluid-attenuated inversion recovery hyperintense vessels in posterior cerebral artery infarction. 61
24052794 2013
17
Reduced retinal ganglion cell complex thickness in patients with posterior cerebral artery infarction detected using spectral-domain optical coherence tomography. 61
22684619 2012
18
[Serious neurological sequelae of a myocarditis]. 61
22736181 2012
19
Posterior cerebral artery infarction: an understudied vascular topography of ischaemic stroke. 61
21418442 2011
20
Bilateral homonymous superior quadrantanopia after traumatic attempts to remove a cockroach impacted in the external auditory canal. 61
21495947 2011
21
Executive dysfunction associated with stroke in the posterior cerebral artery territory. 61
21167720 2011
22
Bilateral posterior cerebral artery infarction. 61
22798298 2010
23
Ipsilateral visual illusion after unilateral posterior cerebral artery infarction: a report of two cases. 61
20542522 2010
24
Isolated posterior cerebral artery infarction caused by carotid artery dissection. 61
19667228 2009
25
Splenium or parahippocampus involvement and its relationship to cognitive decline in posterior cerebral artery infarction. 61
19329320 2009
26
Right sensory alien hand phenomenon from a left pontine hemorrhage. 61
19513334 2009
27
Posterior cerebral artery infarction: diffusion-weighted MRI analysis of 205 patients. 61
19622882 2009
28
Magnetic resonance correlate of hemiparesis in posterior cerebral artery infarction. 61
18984431 2008
29
Neuroimaging in acute posterior cerebral artery infarction. 61
18469674 2008
30
Acute confusional state with posterior cerebral artery infarction: a challenge in the diagnosis of acute stroke at bedside. 61
17966950 2007
31
Malignant posterior cerebral artery infarction. 61
17219035 2006
32
Incidental detection of previously undiagnosed primary breast carcinoma with a gallium-67 scan performed for evaluation of occult infection. 61
17117084 2006
33
Visual neglect after right posterior cerebral artery infarction. 61
16772354 2006
34
Preserved complex emotion-based learning in amnesia. 61
16029879 2006
35
Deafferentation-disconnection neglect induced by posterior cerebral artery infarction. 61
16401846 2006
36
Posterior cerebral artery infarction from middle cerebral artery infarction. 61
15956164 2005
37
[Endovascular treatment of vertebral artery origin stenosis in high risk patients]. 61
15470631 2004
38
Agitated delirium with posterior cerebral artery infarction. 61
12676294 2003
39
Single stroke dementia: insights from 12 cases in Singapore. 61
12417363 2002
40
Sexual headache and stroke in a heavy cannabis smoker. 61
11903547 2002
41
Topiramate in venlafaxine-induced visual hallucinations in an obese patient with a posterior cerebral artery infarction. 61
11476137 2001
42
Posterior cerebral artery infarction caused by cerebral sparganosis-induced vasculitis. 61
11528164 2001
43
Electromyographic (EMG) biofeedback in the comprehensive treatment of central pain and ataxic tremor following thalamic stroke. 61
11218924 2000
44
Is decompressive craniectomy for acute cerebral infarction of any benefit? 61
10773253 2000
45
Differing mechanisms between posterior and middle cerebral artery infarctions. 61
17895092 1998
46
Posterior cerebral artery infarction associated with carotid dissection. 61
17895074 1998
47
Noninvasive assessment of posterior cerebral artery stenosis inducing hemiplegia. 61
9284595 1997
48
SPECT and MRI in posterior cerebral artery infarction and related visual field defects. 61
8509838 1993
49
Loss of visual imagery and loss of visual knowledge--a case study. 61
1484603 1992
50
The topography of callosal reading pathways. A case-control analysis. 61
1486462 1992
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Variations for Posterior Cerebral Artery Infarction

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Expression for Posterior Cerebral Artery Infarction

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Search GEO for disease gene expression data for Posterior Cerebral Artery Infarction.
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Pathways for Posterior Cerebral Artery Infarction

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Pathways related to Posterior Cerebral Artery Infarction according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Response to elevated platelet cytosolic Ca2+ 65
Show member pathways
 12.78 PLG PLAT P2RY1 P2RX4 P2RX3 F9
2
Formation of Fibrin Clot (Clotting Cascade) 65
Show member pathways
 11.46 PLG PLAT F9 F3
3
Complement and coagulation cascades 36 1
11.09 PLG PLAT F9 F3
4
A-beta Plaque Formation and APP Metabolism 64
10.68 PLG PLAT
5
Dissolution of Fibrin Clot 65
10.37 PLG PLAT
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GO Terms for Posterior Cerebral Artery Infarction

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Cellular components related to Posterior Cerebral Artery Infarction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell GO:0005623 9.88 TH PLG P2RY1 P2RX4 P2RX3 MAPT
2 cell surface GO:0009986 9.77 TSPAN33 PLG PLAT P2RY1 F3
3 collagen-containing extracellular matrix GO:0062023 9.73 PLG PLAT F9 F3
4 cell body GO:0044297 9.43 P2RY1 P2RX4 MAPT
5 axon GO:0030424 9.35 TH P2RX4 P2RX3 MYPN MAPT
6 Schaffer collateral - CA1 synapse GO:0098685 9.33 PLG PLAT P2RX3
7 integral component of nuclear inner membrane GO:0005639 9.32 P2RX4 P2RX3
8 terminal bouton GO:0043195 8.8 TH P2RX4 P2RX3

Biological processes related to Posterior Cerebral Artery Infarction according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 response to hypoxia GO:0001666 9.62 TH PLAT P2RX3 MB
2 fibrinolysis GO:0042730 9.51 PLG PLAT
3 response to ATP GO:0033198 9.49 P2RX4 P2RX3
4 positive regulation of calcium-mediated signaling GO:0050850 9.48 P2RX4 P2RX3
5 response to growth factor GO:0070848 9.46 TH P2RY1
6 behavioral response to pain GO:0048266 9.43 P2RX4 P2RX3
7 positive regulation of calcium ion transport into cytosol GO:0010524 9.4 P2RX4 P2RX3
8 purinergic nucleotide receptor signaling pathway GO:0035590 9.37 P2RX4 P2RX3
9 cellular response to ATP GO:0071318 9.33 P2RY1 P2RX4 P2RX3
10 trans-synaptic signaling by BDNF, modulating synaptic transmission GO:0099183 9.26 PLG PLAT
11 hemostasis GO:0007599 9.26 PLG P2RY1 F9 F3
12 blood coagulation GO:0007596 9.17 PLG PLAT P2RY1 P2RX4 P2RX3 F9

Molecular functions related to Posterior Cerebral Artery Infarction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hydrolase activity GO:0016787 9.91 PSMB8 PLG PLAT MEST LIPI F9
2 endopeptidase activity GO:0004175 9.43 PSMB8 PLG F9
3 apolipoprotein binding GO:0034185 9.32 PLG MAPT
4 extracellularly ATP-gated cation channel activity GO:0004931 9.16 P2RX4 P2RX3
5 purinergic nucleotide receptor activity GO:0001614 8.96 P2RX4 P2RX3
6 serine-type endopeptidase activity GO:0004252 8.92 PLG PLAT F9 F3
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Sources for Posterior Cerebral Artery Infarction

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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