MCID: PST093
MIFTS: 16

Posterior Hypospadias

Categories: Fetal diseases, Genetic diseases, Rare diseases, Reproductive diseases

Aliases & Classifications for Posterior Hypospadias

MalaCards integrated aliases for Posterior Hypospadias:

Name: Posterior Hypospadias 59
Perineal, Scrotal or Penoscrotal Hypospadias 59

Classifications:



External Ids:

ICD10 via Orphanet 34 Q54.2 Q54.3
Orphanet 59 ORPHA95706

Summaries for Posterior Hypospadias

MalaCards based summary : Posterior Hypospadias, also known as perineal, scrotal or penoscrotal hypospadias, is related to hypospadias and androgen insensitivity syndrome. An important gene associated with Posterior Hypospadias is MAMLD1 (Mastermind Like Domain Containing 1). Affiliated tissues include skin.

Related Diseases for Posterior Hypospadias

Diseases in the Hypospadias family:

Hypospadias 3, Autosomal Posterior Hypospadias

Diseases related to Posterior Hypospadias via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 hypospadias 29.8 MAMLD1 AR
2 androgen insensitivity syndrome 28.6 MAMLD1 AR
3 peyronie disease 9.9
4 pseudohermaphroditism 9.9
5 urethral diverticulum 9.9

Graphical network of the top 20 diseases related to Posterior Hypospadias:



Diseases related to Posterior Hypospadias

Symptoms & Phenotypes for Posterior Hypospadias

Drugs & Therapeutics for Posterior Hypospadias

Search Clinical Trials , NIH Clinical Center for Posterior Hypospadias

Genetic Tests for Posterior Hypospadias

Anatomical Context for Posterior Hypospadias

MalaCards organs/tissues related to Posterior Hypospadias:

41
Skin

Publications for Posterior Hypospadias

Articles related to Posterior Hypospadias:

(show top 50) (show all 60)
# Title Authors PMID Year
1
Re: Posterior Hypospadias: Evaluation of a Paradigm Shift from Single to Staged Repair. 38
31180293 2019
2
Identification of gene variants in 130 Han Chinese patients with hypospadias by targeted next-generation sequencing. 38
31219235 2019
3
Staged repair of redo and crippled hypospadias: analysis of outcomes and complications. 38
30833176 2019
4
Prenatal imaging of genital defects: clinical spectrum and predictive factors for severe forms. 38
30776193 2019
5
Single Nucleotide Polymorphisms of HAAO and IRX6 Genes as Risk Factors for Hypospadias. 38
30063927 2019
6
Tunica vaginalis flap for urethrocutaneous fistula repair after proximal and mid-shaft hypospadias surgery: A 12-year experience. 38
29859768 2018
7
Posterior hypospadias: Evaluation of a paradigm shift from single to staged repair. 38
28865886 2018
8
Role of uroflowmetry before and after hypospadias repair. 38
29416276 2018
9
Two-stage flap repair of severe hypospadias: Usefulness of the tubularized incised plate urethroplasty. 38
28579133 2017
10
Genotype-phenotype correlation and identification of two novel SRD5A2 mutations in 33 Chinese patients with hypospadias. 38
28663096 2017
11
Interaction between MTHFR 677C>T and periconceptional folic acid supplementation in the risk of Hypospadias. 38
26879531 2016
12
Epidemiology of hypospadias in Europe: a registry-based study. 38
25712311 2015
13
Complications of hypospadias surgery: Experience in a tertiary hospital of a developing country. 38
26712282 2015
14
[Long-term outcomes after hypospadias surgery: Sexual reported outcomes and quality of life in adulthood]. 38
26049263 2015
15
Descriptive Profile Outcomes between Closed and Open Drainage Systems Following Urethroplasty. 38
26267988 2015
16
Molecular basis of non-syndromic hypospadias: systematic mutation screening and genome-wide copy-number analysis of 62 patients. 38
25605705 2015
17
[How and when to evaluate hypospadias?]. 38
23992834 2013
18
Risk factors for different phenotypes of hypospadias: results from a Dutch case-control study. 38
23305310 2013
19
Single- vs. multi-stage repair of proximal hypospadias: The dilemma continues. 38
26558078 2013
20
[Erythropoietin before severe hypospadias repair: fewer complications?]. 38
22364629 2012
21
Abnormalities of the penis in utero--hypospadias on fetal MRI. 38
21631398 2011
22
Z-plasty for sculpturing of the bifid scrotum in severe hypospadias associated with penoscrotal transposition. 38
21527222 2011
23
Long-term outcome of severe hypospadias. 38
20053585 2010
24
[Sex of rearing in 46,XY partial gonadal dysgenesis (case report)]. 38
20097326 2010
25
Hypospadias: surgery and complications. 38
20606395 2010
26
[Snodgrass technique, Duckett repair and bladder mucosa grafting for hypospadias: an analysis of 251 cases]. 38
20180414 2009
27
Corporeal body grafting using buccal mucosa for posterior hypospadias with severe curvature. 38
19692068 2009
28
Factors affecting outcome of tubularized incised plate (TIP) urethroplasty: single-center experience with 500 cases. 38
19632898 2009
29
[Charles II: From spell to genitourinary pathology]. 38
19542589 2009
30
Management of urethrocutaneous fistula following hypospadias repair. 38
18668254 2008
31
[The proximal hypospadias treatment at the teaching hospital of Treichville (Abidjan)]. 38
17634002 2007
32
Hypospadias: an update. 38
17187155 2007
33
The outcome of one-stage hypospadias repairs. 38
18947549 2005
34
[Interest of mobilization of the urethral plate in the release of chordee related to posterior hypospadias]. 38
15822394 2005
35
Comprehensive analysis of tubularized incised-plate urethroplasty in primary and re-operative hypospadias. 38
15142164 2004
36
[Single stage reconstructive operations of the male urethra]. 38
15641547 2003
37
Developmental anomalies and disabilities associated with hypospadias. 38
12050549 2002
38
Hypospadias repair using a double onlay preputial flap. 38
11527203 2001
39
Tubularized incised plate urethroplasty for proximal hypospadias. 38
11119100 2000
40
Tubularized-incised urethral plate urethroplasty: is regular dilatation necessary for success? 38
10510116 1999
41
One-stage repair of hypospadias--experience with 856 cases. 38
9748687 1998
42
[Proximal hypospadias]. 38
9773584 1998
43
[Experiences in the treatment of hypospadias at the University Hospital Center in Treichville (Abidjan)]. 38
9509245 1997
44
Posterior hypospadias: the French operation. 38
8773226 1995
45
Labial mucosa and combined labial/bladder mucosa free graft for urethral reconstruction. 38
8583323 1995
46
Two-layer versus one-layer closure in transverse island flap repair of posterior hypospadias. 38
7623243 1995
47
Posterior hypospadias: long-term followup after reconstructive surgery in the male direction. 38
8411430 1993
48
Urethral stricture in children: treatment by urethroplasty with bladder mucosa graft. 38
1433558 1992
49
Posterior hypospadias repair: a new technical approach. Mobilization of the urethral plate and duplay urethroplasty. 38
1478230 1992
50
[Treatment of hypospadias with a transverse preputial pediculated flap]. 38
1339907 1992

Variations for Posterior Hypospadias

Expression for Posterior Hypospadias

Search GEO for disease gene expression data for Posterior Hypospadias.

Pathways for Posterior Hypospadias

GO Terms for Posterior Hypospadias

Biological processes related to Posterior Hypospadias according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 male gonad development GO:0008584 8.62 MAMLD1 AR

Sources for Posterior Hypospadias

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
Content
Loading form....