Posterior Pituitary Gland Neoplasm disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Posterior Pituitary Gland Neoplasm

MalaCards integrated aliases for Posterior Pituitary Gland Neoplasm:

Name: Posterior Pituitary Gland Neoplasm ¹² ¹⁵

Neoplasm of the Posterior Pituitary ⁷⁰

Posterior Pituitary Tumor ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Endocrine diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:5048

NCIt ⁵⁰ C7157

UMLS ⁷⁰ C1334957

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Summaries for Posterior Pituitary Gland Neoplasm

MalaCards based summary : Posterior Pituitary Gland Neoplasm, also known as neoplasm of the posterior pituitary, is related to pituitary tumors and third ventricle chordoid glioma. An important gene associated with Posterior Pituitary Gland Neoplasm is NKX2-1 (NK2 Homeobox 1). Affiliated tissues include pituitary, and related phenotypes are cardiovascular system and cellular

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Related Diseases for Posterior Pituitary Gland Neoplasm

Diseases related to Posterior Pituitary Gland Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 42)

#	Related Disease	Score	Top Affiliating Genes
1	pituitary tumors	10.0
2	third ventricle chordoid glioma	10.0	NKX2-1 GFAP
3	chordoid glioma	10.0	NKX2-1 GFAP
4	granular cell tumor	10.0	NKX2-1 GFAP
5	cystic teratoma	10.0	NKX2-1 GFAP
6	subependymal giant cell astrocytoma	10.0	NKX2-1 GFAP
7	pneumothorax	9.9	NKX2-1 GFAP
8	keratinizing squamous cell carcinoma	9.9	SMARCB1 NKX2-1
9	oncocytoma	9.9
10	pituitary adenoma	9.9
11	pituicytoma	9.9
12	interstitial lung disease	9.8	NKX2-1 INPP5E
13	rhabdoid meningioma	9.8	SMARCB1 GFAP
14	cerebrovascular benign neoplasm	9.8	SMARCB1 GFAP
15	olfactory nerve neoplasm	9.8	SMARCB1 GFAP
16	cranial nerve malignant neoplasm	9.8	SMARCB1 GFAP
17	pineal gland cancer	9.8	SMARCB1 GFAP
18	central nervous system primitive neuroectodermal neoplasm	9.8	SMARCB1 GFAP
19	cranial nerve neoplasm	9.8	SMARCB1 GFAP
20	ependymoblastoma	9.8	SMARCB1 GFAP
21	clear cell meningioma	9.8	SMARCB1 GFAP
22	spinal cancer	9.8	SMARCB1 GFAP
23	sweat gland benign neoplasm	9.8	SMARCB1 GFAP
24	supratentorial primitive neuroectodermal tumor	9.8	SMARCB1 GFAP
25	medulloepithelioma	9.8	SMARCB1 GFAP
26	cerebral ventricle cancer	9.8	SMARCB1 GFAP
27	cerebrum cancer	9.8	SMARCB1 GFAP
28	supratentorial cancer	9.8	SMARCB1 GFAP
29	papilloma of choroid plexus	9.8	SMARCB1 GFAP
30	pleomorphic xanthoastrocytoma	9.8	SMARCB1 GFAP
31	myoepithelial carcinoma	9.7	SMARCB1 GFAP
32	choroid plexus cancer	9.7	SMARCB1 GFAP
33	myoepithelioma	9.7	SMARCB1 GFAP
34	chondrosarcoma, extraskeletal myxoid	9.7	SMARCB1 GFAP
35	ganglioglioma	9.7	SMARCB1 GFAP
36	neurilemmoma	9.7	SMARCB1 GFAP
37	neuroma	9.7	SMARCB1 GFAP
38	infratentorial cancer	9.6	SMARCB1 GFAP
39	atypical teratoid rhabdoid tumor	9.6	SMARCB1 GFAP
40	teratoma	9.6	SMARCB1 NKX2-1 GFAP
41	chordoma	9.6	SMARCB1 GFAP
42	central nervous system cancer	9.4	SMARCB1 GFAP

Graphical network of the top 20 diseases related to Posterior Pituitary Gland Neoplasm:

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Symptoms & Phenotypes for Posterior Pituitary Gland Neoplasm

MGI Mouse Phenotypes related to Posterior Pituitary Gland Neoplasm:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	cardiovascular system	MP:0005385	9.77	GFAP INPP5E NKX2-1 PKN2 SMARCB1
2	cellular	MP:0005384	9.72	GFAP INPP5E NKX2-1 PKN2 SMARCB1
3	digestive/alimentary	MP:0005381	9.65	GFAP GFRA2 INPP5E NKX2-1 SMARCB1
4	growth/size/body region	MP:0005378	9.63	GFAP GFRA2 INPP5E NKX2-1 PKN2 SMARCB1
5	nervous system	MP:0003631	9.43	GFAP GFRA2 INPP5E NKX2-1 PKN2 SMARCB1
6	vision/eye	MP:0005391	9.02	GFAP GFRA2 INPP5E PKN2 SMARCB1

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Drugs & Therapeutics for Posterior Pituitary Gland Neoplasm

Search Clinical Trials , NIH Clinical Center for Posterior Pituitary Gland Neoplasm

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Genetic Tests for Posterior Pituitary Gland Neoplasm

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Anatomical Context for Posterior Pituitary Gland Neoplasm

MalaCards organs/tissues related to Posterior Pituitary Gland Neoplasm:

⁴⁰

Pituitary

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Publications for Posterior Pituitary Gland Neoplasm

Articles related to Posterior Pituitary Gland Neoplasm:

#	Title	Authors	PMID	Year
1	Adenohypophyseal hyperfunction syndromes and posterior pituitary tumors: prevalence, clinical characteristics, and pathophysiological mechanisms. ⁶¹	Iglesias P...Diez JJ	32613546	2020
2	TTF-1 positive posterior pituitary tumor: Limitations of current treatment and potential new hope in BRAF V600E mutation variants. ⁶¹	Dawoud FM...Uhm JH	32682222	2020
3	Combined Endoscopic Endonasal and Video-microscopic Transcranial Approach with Preoperative Embolization for a Posterior Pituitary Tumor. ⁶¹	Yoshida K...Yoshida K	30092469	2018

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Genes for Posterior Pituitary Gland Neoplasm

Genes related to Posterior Pituitary Gland Neoplasm (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	NKX2-1	NK2 Homeobox 1	Protein Coding	6.95	DISEASES inferred ¹⁵
2	INPP5E	Inositol Polyphosphate-5-Phosphatase E	Protein Coding	5.26	DISEASES inferred ¹⁵
3	GFRA2	GDNF Family Receptor Alpha 2	Protein Coding	5.15	DISEASES inferred ¹⁵
4	GFAP	Glial Fibrillary Acidic Protein	Protein Coding	5.12	DISEASES inferred ¹⁵
5	SMARCB1	SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily B, Member 1	Protein Coding	4.9	DISEASES inferred ¹⁵
6	PKN2	Protein Kinase N2	Protein Coding	4.88	DISEASES inferred ¹⁵

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Variations for Posterior Pituitary Gland Neoplasm

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Expression for Posterior Pituitary Gland Neoplasm

Search GEO for disease gene expression data for Posterior Pituitary Gland Neoplasm.

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Pathways for Posterior Pituitary Gland Neoplasm

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GO Terms for Posterior Pituitary Gland Neoplasm

Cellular components related to Posterior Pituitary Gland Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	intermediate filament cytoskeleton	GO:0045111	8.62	PKN2 GFAP

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