MCID: PST034
MIFTS: 19

Posterior Pituitary Gland Neoplasm

Categories: Cancer diseases, Endocrine diseases

Aliases & Classifications for Posterior Pituitary Gland Neoplasm

MalaCards integrated aliases for Posterior Pituitary Gland Neoplasm:

Name: Posterior Pituitary Gland Neoplasm 12 15
Neoplasm of the Posterior Pituitary 70
Posterior Pituitary Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5048
NCIt 50 C7157
UMLS 70 C1334957

Summaries for Posterior Pituitary Gland Neoplasm

MalaCards based summary : Posterior Pituitary Gland Neoplasm, also known as neoplasm of the posterior pituitary, is related to pituitary tumors and third ventricle chordoid glioma. An important gene associated with Posterior Pituitary Gland Neoplasm is NKX2-1 (NK2 Homeobox 1). Affiliated tissues include pituitary, and related phenotypes are cardiovascular system and cellular

Related Diseases for Posterior Pituitary Gland Neoplasm

Diseases related to Posterior Pituitary Gland Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 42)
# Related Disease Score Top Affiliating Genes
1 pituitary tumors 10.0
2 third ventricle chordoid glioma 10.0 NKX2-1 GFAP
3 chordoid glioma 10.0 NKX2-1 GFAP
4 granular cell tumor 10.0 NKX2-1 GFAP
5 cystic teratoma 10.0 NKX2-1 GFAP
6 subependymal giant cell astrocytoma 10.0 NKX2-1 GFAP
7 pneumothorax 9.9 NKX2-1 GFAP
8 keratinizing squamous cell carcinoma 9.9 SMARCB1 NKX2-1
9 oncocytoma 9.9
10 pituitary adenoma 9.9
11 pituicytoma 9.9
12 interstitial lung disease 9.8 NKX2-1 INPP5E
13 rhabdoid meningioma 9.8 SMARCB1 GFAP
14 cerebrovascular benign neoplasm 9.8 SMARCB1 GFAP
15 olfactory nerve neoplasm 9.8 SMARCB1 GFAP
16 cranial nerve malignant neoplasm 9.8 SMARCB1 GFAP
17 pineal gland cancer 9.8 SMARCB1 GFAP
18 central nervous system primitive neuroectodermal neoplasm 9.8 SMARCB1 GFAP
19 cranial nerve neoplasm 9.8 SMARCB1 GFAP
20 ependymoblastoma 9.8 SMARCB1 GFAP
21 clear cell meningioma 9.8 SMARCB1 GFAP
22 spinal cancer 9.8 SMARCB1 GFAP
23 sweat gland benign neoplasm 9.8 SMARCB1 GFAP
24 supratentorial primitive neuroectodermal tumor 9.8 SMARCB1 GFAP
25 medulloepithelioma 9.8 SMARCB1 GFAP
26 cerebral ventricle cancer 9.8 SMARCB1 GFAP
27 cerebrum cancer 9.8 SMARCB1 GFAP
28 supratentorial cancer 9.8 SMARCB1 GFAP
29 papilloma of choroid plexus 9.8 SMARCB1 GFAP
30 pleomorphic xanthoastrocytoma 9.8 SMARCB1 GFAP
31 myoepithelial carcinoma 9.7 SMARCB1 GFAP
32 choroid plexus cancer 9.7 SMARCB1 GFAP
33 myoepithelioma 9.7 SMARCB1 GFAP
34 chondrosarcoma, extraskeletal myxoid 9.7 SMARCB1 GFAP
35 ganglioglioma 9.7 SMARCB1 GFAP
36 neurilemmoma 9.7 SMARCB1 GFAP
37 neuroma 9.7 SMARCB1 GFAP
38 infratentorial cancer 9.6 SMARCB1 GFAP
39 atypical teratoid rhabdoid tumor 9.6 SMARCB1 GFAP
40 teratoma 9.6 SMARCB1 NKX2-1 GFAP
41 chordoma 9.6 SMARCB1 GFAP
42 central nervous system cancer 9.4 SMARCB1 GFAP

Graphical network of the top 20 diseases related to Posterior Pituitary Gland Neoplasm:



Diseases related to Posterior Pituitary Gland Neoplasm

Symptoms & Phenotypes for Posterior Pituitary Gland Neoplasm

MGI Mouse Phenotypes related to Posterior Pituitary Gland Neoplasm:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.77 GFAP INPP5E NKX2-1 PKN2 SMARCB1
2 cellular MP:0005384 9.72 GFAP INPP5E NKX2-1 PKN2 SMARCB1
3 digestive/alimentary MP:0005381 9.65 GFAP GFRA2 INPP5E NKX2-1 SMARCB1
4 growth/size/body region MP:0005378 9.63 GFAP GFRA2 INPP5E NKX2-1 PKN2 SMARCB1
5 nervous system MP:0003631 9.43 GFAP GFRA2 INPP5E NKX2-1 PKN2 SMARCB1
6 vision/eye MP:0005391 9.02 GFAP GFRA2 INPP5E PKN2 SMARCB1

Drugs & Therapeutics for Posterior Pituitary Gland Neoplasm

Search Clinical Trials , NIH Clinical Center for Posterior Pituitary Gland Neoplasm

Genetic Tests for Posterior Pituitary Gland Neoplasm

Anatomical Context for Posterior Pituitary Gland Neoplasm

MalaCards organs/tissues related to Posterior Pituitary Gland Neoplasm:

40
Pituitary

Publications for Posterior Pituitary Gland Neoplasm

Articles related to Posterior Pituitary Gland Neoplasm:

# Title Authors PMID Year
1
Adenohypophyseal hyperfunction syndromes and posterior pituitary tumors: prevalence, clinical characteristics, and pathophysiological mechanisms. 61
32613546 2020
2
TTF-1 positive posterior pituitary tumor: Limitations of current treatment and potential new hope in BRAF V600E mutation variants. 61
32682222 2020
3
Combined Endoscopic Endonasal and Video-microscopic Transcranial Approach with Preoperative Embolization for a Posterior Pituitary Tumor. 61
30092469 2018

Variations for Posterior Pituitary Gland Neoplasm

Expression for Posterior Pituitary Gland Neoplasm

Search GEO for disease gene expression data for Posterior Pituitary Gland Neoplasm.

Pathways for Posterior Pituitary Gland Neoplasm

GO Terms for Posterior Pituitary Gland Neoplasm

Cellular components related to Posterior Pituitary Gland Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament cytoskeleton GO:0045111 8.62 PKN2 GFAP

Sources for Posterior Pituitary Gland Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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