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MCID: PST005
MIFTS: 49

Posterior Uveitis

Categories: Rare diseases, Eye diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Posterior Uveitis

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MalaCards integrated aliases for Posterior Uveitis:

Name: Posterior Uveitis 12 76 53 15
Uveitis, Posterior 12 76 44 73
Uveitis Posterior 55

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:12574
MeSH 44 D015866
NCIt 50 C35111
UMLS 73 C0042167
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Summaries for Posterior Uveitis

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MalaCards based summary : Posterior Uveitis, also known as uveitis, posterior, is related to chorioretinitis and choroiditis, and has symptoms including eye manifestations An important gene associated with Posterior Uveitis is SAG (S-Antigen Visual Arrestin), and among its related pathways/superpathways are Allograft rejection and IL-2 Pathway. The drugs Fluocinolone Acetonide and Methylprednisolone have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and endothelial, and related phenotype is vision/eye.

Wikipedia : 76 Uveitis is the inflammation of the uvea, the pigmented layer that lies between the inner retina and the... more...

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Related Diseases for Posterior Uveitis

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Diseases in the Uveitis family:

Posterior Uveitis Intermediate Uveitis
Infectious Anterior Uveitis Anterior Uveitis
Infectious Posterior Uveitis

Diseases related to Posterior Uveitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 173)
# Related Disease Score Top Affiliating Genes
1 chorioretinitis 32.5 RBP3 SAG
2 choroiditis 32.2 CFH TNF
3 panuveitis 30.4 RBP3 SAG TNF
4 mumps 29.6 IFNG IL2 TNF
5 acquired immunodeficiency syndrome 29.5 IFNG IL2 TNF
6 intermediate uveitis 29.5 IFNG IL2 IL2RA TNF
7 uveitis 29.2 CAPN5 IFNG IL2RA RBP3 SAG TNF
8 multiple sclerosis 28.9 IFNG IL2 IL2RA TNF
9 autoimmune disease 28.1 IFNG IL2 IL2RA RBP3 TNF
10 infectious posterior uveitis 12.2
11 idiopathic posterior uveitis 12.2
12 birdshot chorioretinopathy 11.1
13 vitreoretinopathy, neovascular inflammatory 11.0
14 retinal vasculitis 11.0
15 staphylococcal toxic shock syndrome 10.7 IFNG TNF
16 trichosporonosis 10.6 IFNG TNF
17 chronic beryllium disease 10.6 IFNG TNF
18 meconium aspiration syndrome 10.6 IFNG TNF
19 soft tissue sarcoma 10.6 IFNG TNF
20 cytomegalovirus retinitis 10.6 IFNG TNF
21 tuberculous peritonitis 10.6 IFNG TNF
22 primary systemic mycosis 10.6 IFNG TNF
23 poliomyelitis 10.6 IFNG TNF
24 orofacial granulomatosis 10.6 IFNG TNF
25 hemorrhagic fever 10.6 IFNG TNF
26 ileocolitis 10.6 IL2RA TNF
27 pleural tuberculosis 10.5 IFNG TNF
28 hyperlucent lung 10.5 IFNG IL2RA
29 spotted fever 10.5 IFNG TNF
30 aseptic meningitis 10.5 IFNG TNF
31 oral tuberculosis 10.5 IL2 TNF
32 lichen disease 10.5 IFNG TNF
33 plasmodium vivax malaria 10.5 IFNG TNF
34 chronic graft versus host disease 10.5 IFNG IL2RA
35 hepatitis e 10.5 IFNG TNF
36 streptococcal toxic-shock syndrome 10.5 IL2 TNF
37 folliculitis 10.5 IFNG IL2RA
38 farmer's lung 10.5 IL2 TNF
39 toxic oil syndrome 10.5 IFNG IL2RA
40 variola major 10.5 IFNG IL2
41 oligoarticular juvenile idiopathic arthritis 10.5 IL2RA TNF
42 q fever 10.5 IFNG TNF
43 stromal keratitis 10.5 IL2RA TNF
44 fixed drug eruption 10.4 IFNG IL2
45 berylliosis 10.4 IFNG IL2
46 burning mouth syndrome 10.4 IL2 TNF
47 hypersplenism 10.4 IFNG IL2RA
48 rasmussen encephalitis 10.4 IFNG TNF
49 atopic keratoconjunctivitis 10.4 IFNG IL2
50 chronic active epstein-barr virus infection 10.4 IFNG IL2

Graphical network of the top 20 diseases related to Posterior Uveitis:



Diseases related to Posterior Uveitis
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Symptoms & Phenotypes for Posterior Uveitis

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UMLS symptoms related to Posterior Uveitis:


eye manifestations

MGI Mouse Phenotypes related to Posterior Uveitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 vision/eye MP:0005391 9.23 CFH IFNG IL2 IL2RA KIAA1109 RBP3
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Drugs & Therapeutics for Posterior Uveitis

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Drugs for Posterior Uveitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 105)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fluocinolone Acetonide Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 67-73-2 6215
2
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 83-43-2 6741
3
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-24-8 5755
4
Azathioprine Approved Phase 4,Phase 2 446-86-6 2265
5
Infliximab Approved Phase 4,Phase 1,Phase 2 170277-31-3
6
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1959-05-2, 59-05-2 126941
7
Mycophenolate mofetil Approved, Investigational Phase 4,Phase 3 128794-94-5 5281078
8
Mycophenolic acid Approved Phase 4,Phase 3 24280-93-1 446541
9
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 50-02-2 5743
10
Chlorambucil Approved Phase 4 305-03-3 2708
11
Cyclophosphamide Approved, Investigational Phase 4,Phase 2 50-18-0, 6055-19-2 2907
12
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2 53-03-2 5865
13
Tacrolimus Approved, Investigational Phase 4 104987-11-3 445643 439492
14
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 124-94-7 31307
15
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 59-30-3 6037
16
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 58-05-9 143 6006
17 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
18 glucocorticoids Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
19 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
20 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
21 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
22 Antiemetics Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
23 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
24 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
25 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
26 Methylprednisolone acetate Phase 4,Phase 3,Phase 2,Not Applicable
27 Methylprednisolone Hemisuccinate Phase 4,Phase 3,Phase 2,Not Applicable
28 Neuroprotective Agents Phase 4,Phase 3,Not Applicable
29 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
30 Prednisolone acetate Phase 4,Phase 3,Phase 2,Not Applicable
31 Prednisolone hemisuccinate Phase 4,Phase 3,Phase 2,Not Applicable
32 Prednisolone phosphate Phase 4,Phase 3,Phase 2,Not Applicable
33 Protective Agents Phase 4,Phase 3,Not Applicable
34 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1
35 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Phase 1
36 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
37 Antimetabolites Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
38 Antimetabolites, Antineoplastic Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
39 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
40 Antitubercular Agents Phase 4,Phase 3
41 Cyclosporins Phase 4,Phase 3
42 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
43 BB 1101 Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
44 Dexamethasone acetate Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1177-87-3
45 HIV Protease Inhibitors Phase 4,Phase 3,Phase 2,Not Applicable
46
protease inhibitors Phase 4,Phase 3,Phase 2,Not Applicable
47 Dermatologic Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
48 Folic Acid Antagonists Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
49 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
50 Vitamin B Complex Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable

Interventional clinical trials:

(show top 50) (show all 80)
# Name Status NCT ID Phase Drugs
1 Flucinolone Acetonide Implant for Treating Refractory Ocular Behcet's Disease Unknown status NCT00720928 Phase 4 flucinolone acetonide
2 The Efficacy of Methylprednisolone in the Treatment of Patients With Ocular Involvement in Behcet's Disease Unknown status NCT01306955 Phase 4 methylorednisolone
3 Multicenter Uveitis Steroid Treatment (MUST) Trial Completed NCT00132691 Phase 4 fluocinolone acetonide intraocular implant;oral corticosteroid with immunosuppressive agents as needed
4 Study of H.P. ACTHAR Subcutaneous Gelatin (Gel)(Highly Purified Gel Injection) in Uveitis Patients Completed NCT02764697 Phase 4 H.P. ACTHAR SUBCUTANEOUS GEL INJECTION
5 Study of the Effectiveness of Ozurdex for the Control of Uveitis Recruiting NCT02049476 Phase 4 Dexamethasone pellet
6 Efficacy and Safety of H.P. ACTHAR GEL in Adults With Retinal Vasculitis Recruiting NCT03066869 Phase 4 H.P. ACTHAR GEL
7 Efficacy Study of Methotrexate to Treat Sarcoid-associated Uveitis Terminated NCT00918554 Phase 4 Methotrexate;Placebo
8 To Compare Intravitreal Clindamycin & Dexamethasone With Classic Treatment of Toxoplasmic Retinochoroiditis Unknown status NCT00372294 Phase 3 pyrimethamine-sulfadiazine + prednisolone;Clindamycin+Dexamethasone
9 A Study of the Safety and Efficacy of a New Treatment for Non-Infectious Intermediate or Posterior Uveitis Completed NCT00333814 Phase 2, Phase 3 Dexamethasone;dexamethasone;Sham injection
10 Efficacy and Safety of Adalimumab in Subjects With Inactive Uveitis Completed NCT01124838 Phase 3 Adalimumab;Prednisone;Placebo
11 Safety and Efficacy of Fluocinolone Acetonide Intravitreal Implants Completed NCT00407082 Phase 2, Phase 3 fluocinolone acetonide intravitreal implant;Fluocinolone acetonide 2.1mg
12 Efficacy and Safety of Adalimumab in Patients With Active Uveitis Completed NCT01138657 Phase 3 Prednisone;Placebo
13 Phase III Study in Refractory Behcet's Disease Completed NCT00995709 Phase 3 AIN457;AIN457;Placebo
14 A Controlled, Multi-center Study of the Utilization and Safety of the MK II Inserter and the Safety of the FAI Insert in Subjects With Non-infectious Uveitis Affecting the Posterior Segment of the Eye Completed NCT02748512 Phase 3 FAI insert
15 Interferon-alpha2a Versus Cyclosporin A for Severe Ocular Behcet`s Disease (INCYTOB) Completed NCT00167583 Phase 3 Cyclosporin A;Interferon-alpha2a
16 A Study of the Long-term Safety and Efficacy of Adalimumab in Subjects With Intermediate-, Posterior-, or Pan-uveitis Completed NCT01148225 Phase 3 adalimumab
17 Suprachoroidal Injection of CLS-TA in Subjects Non-infectious Uveitis Completed NCT03097315 Phase 3
18 Suprachoroidal Injection of CLS-TA in Subjects With Macular Edema Associated With Non-infectious Uveitis Completed NCT02595398 Phase 3 4mg CLS-TA Suprachoriodal Injection;Sham Procedure
19 A Study of LX211 in Clinically Quiescent Non-infectious Intermediate, Anterior and Intermediate, Posterior or Pan-Uveitis Completed NCT00404742 Phase 3 Placebo;LX211;LX211;LX211
20 A Study of LX211 in Active Sight Threatening, Non-infectious Intermediate-, Anterior and Intermediate-, Posterior-, or Pan-Uveitis Completed NCT00404612 Phase 3 Placebo;LX211;LX211;LX211
21 Myfortic for the Treatment of Non-infectious Intermediate Uveitis Completed NCT01092533 Phase 3 Myfortic;Decortin
22 Intravitreal Bevacizumab for Inflammatory Neovascular Membranes Completed NCT00407121 Phase 3 Bevacizumab
23 Randomized, Controlled Trial to Test the Efficacy of Interferon Beta in the Treatment of Intermediate Uveitis Completed NCT00344253 Phase 3 Interferon beta;Methotrexate
24 Safety and Efficacy Study of a Fluocinolone Acetonide Intravitreal (FAI) Insert in Subjects With Chronic Non-infectious Posterior Uveitis Active, not recruiting NCT02746991 Phase 3 Sham Injection;FAI Insert
25 Safety and Efficacy of an Injectable Fluocinolone Acetonide Intravitreal Insert Active, not recruiting NCT01694186 Phase 3 FAI insert;Sham injection
26 38 Week Extension Study to CAIN457C2303 Terminated NCT01093846 Phase 3 AIN457;AIN457;Placebo AIN457
27 Safety and Efficacy of AIN457 in Patients With Active Non-infectious Uveitis Terminated NCT01095250 Phase 3 AIN457;AIN457;AIN457;Placebo
28 Safety and Efficacy of AIN457 in Patients With Quiescent Non-infectious Uveitis Terminated NCT01032915 Phase 3 Placebo
29 Long-term Safety of Gevokizumab in the Treatment of Patients With Chronic Non-infectious Uveitis (EYEGUARD-X) Terminated NCT02375685 Phase 3
30 Safety and Efficacy Study of Gevokizumab to Treat Non-infectious Uveitis Controlled With Systemic Treatment Terminated NCT01747538 Phase 3 Placebo;Dose 1 gevokizumab;Dose 2 gevokizumab
31 Safety and Efficacy Study of Gevokizumab to Treat Active Non-infectious Uveitis Terminated NCT01684345 Phase 3 Placebo;Dose 1 gevokizumab;Dose 2 gevokizumab
32 Extension Study to Assess Safety and Efficacy of AIN457 in Patients With Active Non-infectious Uveitis Terminated NCT01103024 Phase 3
33 An Open-label, Rollover Study Providing Continued Dosing of Gevokizumab in Order to Assess Long-term Gevokizumab Safety Data Terminated NCT02258854 Phase 3 Dose 2 gevokizumab
34 Safety and Efficacy of AIN457 in Patients With Quiescent Non-infectious Uveitis Terminated NCT01090310 Phase 3 AIN457;Placebo
35 Study to Evaluate the Long Term Use of Treatment With AIN457 for Uveitis Withdrawn NCT01327664 Phase 3
36 Combination Daclizumab/Denileukin Diftitox to Treat Uveitis Completed NCT00326508 Phase 2 Daclizumab
37 Safety, Tolerability, and Efficacy of AEB071 in the Treatment of Uveitis Completed NCT00615693 Phase 2 AEB071
38 Safety,Tolerability and Efficacy of Intravitreal LFG316 in Patients With Active Non-infectious Intermediate-, posterior-or Panuveitis , Completed NCT01526889 Phase 2 LFG316;Conventional Therapy
39 Evaluation of Birdshot Retine Choroidopathy Treatment by Either Steroid or Interferon alpha2a Completed NCT00508040 Phase 2 interferon alpha 2a;prednisone
40 Daclizumab to Treat Non-Infectious Sight-Threatening Uveitis Completed NCT00070759 Phase 2 Daclizumab
41 Safety Study of Suprachoroidal Triamcinolone Acetonide Via Microneedle to Treat Uveitis Completed NCT01789320 Phase 1, Phase 2 triamcinolone acetonide (Triesence®)
42 Rituximab for the Treatment of Severe Ocular Manifestations of Behcet's Disease Completed NCT00664599 Phase 2 Rituximab;Cytotoxic Combination
43 Intravitreal Infliximab in Refractory Uveitis in Behcet's Disease: A Safety and Efficacy Clinical Study Completed NCT02620618 Phase 1, Phase 2 Intravitreal Infliximab
44 Suprachoroidal Injection of Triamcinolone Acetonide in Subjects With Macular Edema Following Non-Infectious Uveitis Completed NCT02255032 Phase 2 4 mg CLS-TA;0.8 mg CLS-TA
45 Safety and Efficacy of AIN457 in Noninfectious Uveitis Completed NCT00685399 Phase 2 AIN457;AIN 457;AIN457
46 Research Study in Patients With Persistent Macular Edema Completed NCT00035906 Phase 2 DEX PS DDS®
47 Effect of Spironolactone in Treating Chronic Non-resolutive Central Serous Chorioretinitis Completed NCT01552044 Phase 1, Phase 2 Spironolactone;Placebo
48 Treatment of Exudative and Vasogenic Chorioretinal Diseases Including Variants of AMD and Other CNV Related Maculopathy Completed NCT00470977 Phase 1, Phase 2 ranibizumab injection (0.5 mg)
49 Efficacy and Safety of Ustekinumab, a Human Monoclonal Anti-IL-12/IL-23 Antibody, in Patients With Behçet Disease Recruiting NCT02648581 Phase 2 Subcutaneous Ustekinumab
50 Intravitreal Sirolimus as Therapeutic Approach to Uveitis Recruiting NCT01280669 Phase 2 Intravitreal injection 440mcg;Intravitreal injection of sirolimus 880mcg

Search NIH Clinical Center for Posterior Uveitis

Cochrane evidence based reviews: uveitis, posterior

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Genetic Tests for Posterior Uveitis

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Anatomical Context for Posterior Uveitis

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MalaCards organs/tissues related to Posterior Uveitis:

41
Eye, Retina, Endothelial, Testes, T Cells, Brain
Sources

Publications for Posterior Uveitis

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Articles related to Posterior Uveitis:

(show top 50) (show all 220)
# Title Authors Year
1
DETECTION OF TYPE 1 CHOROIDAL NEOVASCULAR MEMBRANES USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN TUBERCULAR POSTERIOR UVEITIS. ( 29689028 )
2018
2
Superficial and deep retinal foveal avascular zone OCTA findings of non-infectious anterior and posterior uveitis. ( 29980918 )
2018
3
Need for Quantitative Measurement Methods for Posterior Uveitis: Comparison of Dual FA/ICGA Angiography, EDI-OCT Choroidal Thickness and SUN Vitreous Haze Evaluation in Stromal Choroiditis. ( 29669371 )
2018
4
Inner Retinal Microvasculature Damage Correlates With Outer Retinal Disruption During Remission in BehAset's Posterior Uveitis by Optical Coherence Tomography Angiography. ( 29625452 )
2018
5
Bilateral ipilimumab-induced posterior uveitis following treatment for metastatic choroidal melanoma. ( 29653019 )
2018
6
Morphometric features on enhanced depth imaging optical coherence tomography scans in idiopathic posterior uveitis or panuveitis. ( 28585111 )
2017
7
Vogt-Koyanagi-Harada disease-like posterior uveitis in the course of nivolumab (anti-PD-1 antibody), interposed by vemurafenib (BRAF inhibitor), for metastatic cutaneous malignant melanoma. ( 28469878 )
2017
8
The Effectiveness of Pre- and Postoperative Infliximab in Controlling BehAset's Disease Posterior Uveitis in Patients Undergoing Vitrectomy: A Preliminary Study. ( 28484648 )
2017
9
A systematic review and economic evaluation of adalimumab and dexamethasone for treating non-infectious intermediate uveitis, posterior uveitis or panuveitis in adults. ( 29183563 )
2017
10
Reply to Lee and colleagues-Viral posterior uveitis. ( 28624250 )
2017
11
Re: Jaffe etA al.: Injectable fluocinolone acetonide long-acting implant for noninfectious intermediate uveitis, posterior uveitis, and panuveitis: 2-year results (Ophthalmology. 2016;123:1940-1948). ( 28734339 )
2017
12
Bilateral posterior uveitis associated with Zika virus infection. ( 27939402 )
2017
13
Re: Jaffe etA al.: Injectable fluocinolone acetonide long-acting implant for noninfectious intermediate uveitis, posterior uveitis, and panuveitis: two-year results (Ophthalmology. 2016;123:1940-1948). ( 28335961 )
2017
14
LONG-TERM OUTCOMES OF RITUXIMAB THERAPY IN PATIENTS WITH NONINFECTIOUS POSTERIOR UVEITIS REFRACTORY TO CONVENTIONAL IMMUNOSUPPRESSIVE THERAPY. ( 28225369 )
2017
15
Stalagmite-like preretinal inflammatory deposits in vitrectomized eyes with posterior uveitis. ( 28924415 )
2017
16
Viral Posterior Uveitis-Author's reply. ( 28606632 )
2017
17
Long-term Change of Subfoveal Choroidal Thickness in BehAset's Disease Patients with Posterior Uveitis. ( 28080153 )
2017
18
Effect of Adalimumab on Visual Functioning in Patients With Noninfectious Intermediate Uveitis, Posterior Uveitis, and Panuveitis in the VISUAL-1 and VISUAL-2 Trials. ( 28426849 )
2017
19
Dexamethasone implants in paediatric patients with noninfectious intermediate or posterior uveitis: first prospective exploratory case series. ( 29246154 )
2017
20
PEMBROLIZUMAB ADMINISTRATION ASSOCIATED WITH POSTERIOR UVEITIS. ( 27490976 )
2016
21
Risk of Ocular Complications in Patients with Noninfectious Intermediate Uveitis, Posterior Uveitis, or Panuveitis. ( 26712559 )
2016
22
Management of noninfectious posterior uveitis with intravitreal drug therapy. ( 27789936 )
2016
23
Viral Posterior Uveitis. ( 28012878 )
2016
24
The association between the parenchymal neurological involvement and posterior uveitis in BehAset's syndrome. ( 27791948 )
2016
25
Posterior Uveitis. ( 26502276 )
2016
26
The Effectiveness of Intraocular Methotrexate in the Treatment of Posterior Uveitis in BehAset's Disease Patients Compared to Retrobulbar Steroids Injection. ( 28070412 )
2016
27
A case of unilateral and spontaneously resolving posterior uveitis with overlapping features of Vogt-Koyanagi-Harada disease and Acute Posterior Multifocal Placoid Pigment Epitheliopathy. ( 27652046 )
2016
28
DELINEATION OF CHOROIDAL AND RETINAL LESIONS IN POSTERIOR UVEITIS BY MULTISPECTRAL WIDE-FIELD SCANNING LASER OPHTHALMOSCOPY. ( 27152831 )
2016
29
Failure to Integrate Quantitative Measurement Methods of Ocular Inflammation Hampers Clinical Practice and Trials on New Therapies for Posterior Uveitis. ( 27937751 )
2016
30
In-vivo immunofluorescent imaging in cases of posterior uveitis. ( 27063084 )
2016
31
Role of Ultra-Wide Field Imaging in the Management of Tubercular Posterior Uveitis. ( 26735848 )
2016
32
Injectable Fluocinolone Acetonide Long-Acting Implant for Noninfectious Intermediate Uveitis, Posterior Uveitis, and Panuveitis: Two-Year Results. ( 27421623 )
2016
33
Detection of mild papilloedema in posterior uveitis using spectral domain optical coherence tomography. ( 27872047 )
2016
34
PRESUMED POSTERIOR UVEITIS RELATED TO EHRLICHIA EXPOSURE. ( 26352324 )
2015
35
Benefits of Systemic Anti-inflammatory Therapy versus Fluocinolone Acetonide Intraocular Implant for Intermediate Uveitis, Posterior Uveitis, and Panuveitis: Fifty-four-Month Results of the Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow-up Study. ( 26298715 )
2015
36
The Great Imitator: Ocular Syphilis Presenting as Posterior Uveitis. ( 26151369 )
2015
37
Syphilitic posterior uveitis. ( 25856651 )
2015
38
The role of fundus autofluorescence imaging in the study of the course of posterior uveitis disorders. ( 25695054 )
2015
39
Central Serous Chorioretinopathy Misdiagnosed as Posterior Uveitis and the Vicious Circle of Corticosteroid Therapy. ( 26730317 )
2015
40
Reply to Hall J: "Use of the Fluocinolone Acetonide Intravitreal Implant for the Treatment of Noninfectious Posterior Uveitis: 3-Year Results of a Randomized Clinical Trial in a Predominantly Asian Population" : Virender S. Sangwan, P. Andrew Pearson, Hemanth Paul, Timothy L. Comstock. ( 25794551 )
2015
41
Comment on: "Use of the Fluocinolone Acetonide Intravitreal Implant for the Treatment of Noninfectious Posterior Uveitis: 3-Year Results of a Randomized Clinical Trial in a Predominantly Asian Population". ( 25786593 )
2015
42
Quality of Life and Risks Associated with Systemic Anti-inflammatory Therapy versus Fluocinolone Acetonide Intraocular Implant for Intermediate Uveitis, Posterior Uveitis, or Panuveitis: Fifty-four-Month Results of the Multicenter Uveitis Steroid Treatment Trial and Follow-up Study. ( 26298718 )
2015
43
Efficacy and tolerability of bilateral sustained-release dexamethasone intravitreal implants for the treatment of noninfectious posterior uveitis and macular edema secondary to retinal vein occlusion. ( 26150689 )
2015
44
Results of intravitreal dexamethasone implant 0.7 mg (OzurdexAr) in non-infectious posterior uveitis. ( 26309888 )
2015
45
Factors affecting therapeutic decisions in intermediate and posterior uveitis. ( 25449000 )
2015
46
Development and Evaluation of Dexamethasone Nanomicelles with Potential for Treating Posterior Uveitis After Topical Application. ( 25839185 )
2015
47
Intravitreal Dexamethasone Implant for Treatment of Refractory BehAset Posterior Uveitis: One-year Follow-up Results. ( 26470764 )
2015
48
Uveal effusion syndrome mimicking severe chronic posterior uveitis: a case series of seven eyes of four patients. ( 26376819 )
2015
49
Spectral-domain optical coherence tomography appearance of preretinal granulomas in toxoplasma posterior uveitis with arterial occlusion. ( 26358432 )
2015
50
Intermediate uveitis, posterior uveitis, and panuveitis in the Mid-Atlantic USA. ( 26345421 )
2015
Sources

Variations for Posterior Uveitis

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Expression for Posterior Uveitis

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Search GEO for disease gene expression data for Posterior Uveitis.
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Pathways for Posterior Uveitis

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Pathways related to Posterior Uveitis according to GeneCards Suite gene sharing:

(show all 32)
# Super pathways Score Top Affiliating Genes
1
Allograft rejection 1 37
Show member pathways
 12.66 IFNG IL2 IL2RA TNF
2
IL-2 Pathway 64
Show member pathways
 12.58 IFNG IL2 IL2RA TNF
3
Influenza A 37
Show member pathways
 12.57 IFNG IL2 IL2RA TNF
4
Regulation of IFNA signaling 66
Show member pathways
 12.43 IFNG IL2 IL2RA TNF
5
NF-kappaB Signaling 4
12.36 IFNG IL2 IL2RA TNF
6
Apoptosis Pathway 72
Show member pathways
 12.25 CAPN5 IL2 IL2RA
7
T cell receptor signaling pathway 37
Show member pathways
 12.23 IFNG IL2 TNF
8
Th17 cell differentiation 37
Show member pathways
 12.23 IFNG IL2 IL2RA TNF
9
HTLV-I infection 37
12.22 IL2 IL2RA TNF
10
Folate Metabolism 1
Show member pathways
 12.14 IFNG IL2 TNF
11
Th1 Differentiation Pathway 65
Show member pathways
 12.06 IFNG IL2 TNF
12
IL-2 Signaling Pathway 1
Show member pathways
 11.88 IFNG IL2 IL2RA
13
Spinal Cord Injury 1
11.82 IFNG IL2 TNF
14
IL12-mediated signaling events 1
Show member pathways
 11.79 IFNG IL2 IL2RA
15
Jak-Stat Signaling Pathway 67
11.71 IFNG IL2 IL2RA
16
Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers 65
11.62 IFNG IL2 IL2RA TNF
17
Dendritic Cells Developmental Lineage Pathway 65
11.57 IFNG IL2 TNF
18
Photodynamic therapy-induced NF-kB survival signaling 1
Show member pathways
 11.47 IFNG IL2 TNF
19
Photodynamic therapy-induced AP-1 survival signaling. 1
11.36 IFNG IL2 TNF
20
Innate Lymphoid Cell Differentiation Pathways 65
11.36 IFNG IL2 IL2RA TNF
21
Transcription_Role of VDR in regulation of genes involved in osteoporosis 22
11.31 IFNG TNF
22
Aryl Hydrocarbon Receptor Pathway 1
11.31 IFNG IL2 TNF
23
Th2 Differentiation Pathway 65
11.27 IFNG IL2 IL2RA
24
African trypanosomiasis 37
11.18 IFNG TNF
25
Development and heterogeneity of the ILC family 1
11.14 IFNG TNF
26
Calcineurin-regulated NFAT-dependent transcription in lymphocytes 1
Show member pathways
 11.14 IFNG IL2 IL2RA TNF
27
Inflammatory Response Pathway 1
11.1 IFNG IL2 IL2RA
28
Immune response_IL-12 signaling pathway 22
Show member pathways
 11.09 IFNG IL2RA
29
OX40 Pathway 64
11.03 IFNG IL2
30
Cytokines and Inflammatory Response 1
11.02 IFNG IL2 TNF
31
IL12 signaling mediated by STAT4 1
10.94 IFNG IL2 IL2RA
32
Downstream signaling in naive CD8+ T cells 1
Show member pathways
 10.71 IFNG IL2 IL2RA TNF
Sources

GO Terms for Posterior Uveitis

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Cellular components related to Posterior Uveitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intracellular GO:0005622 9.02 CAPN5 IFNG IL2 IL2RA TNF

Biological processes related to Posterior Uveitis according to GeneCards Suite gene sharing:

(show all 19)
# Name GO ID Score Top Affiliating Genes
1 cell surface receptor signaling pathway GO:0007166 9.76 IFNG IL2RA SAG
2 MAPK cascade GO:0000165 9.73 IL2 IL2RA TNF
3 immune response GO:0006955 9.73 IFNG IL2 IL2RA TNF
4 positive regulation of protein phosphorylation GO:0001934 9.65 IFNG IL2 TNF
5 extrinsic apoptotic signaling pathway GO:0097191 9.58 IFNG TNF
6 positive regulation of interferon-gamma production GO:0032729 9.57 IL2 TNF
7 positive regulation of nitric oxide biosynthetic process GO:0045429 9.55 IFNG TNF
8 protein import into nucleus, translocation GO:0000060 9.54 IFNG TNF
9 positive regulation of activated T cell proliferation GO:0042104 9.52 IL2 IL2RA
10 positive regulation of protein complex assembly GO:0031334 9.51 IFNG TNF
11 positive regulation of osteoclast differentiation GO:0045672 9.49 IFNG TNF
12 positive regulation of T cell differentiation GO:0045582 9.46 IL2 IL2RA
13 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.4 IFNG TNF
14 interleukin-2-mediated signaling pathway GO:0038110 9.37 IL2 IL2RA
15 negative regulation of lymphocyte proliferation GO:0050672 9.32 IL2 IL2RA
16 regulation of T cell homeostatic proliferation GO:0046013 9.26 IL2 IL2RA
17 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.16 IFNG TNF
18 positive regulation of vitamin D biosynthetic process GO:0060557 8.96 IFNG TNF
19 regulation of regulatory T cell differentiation GO:0045589 8.8 IFNG IL2 IL2RA

Molecular functions related to Posterior Uveitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 8.8 IFNG IL2 TNF
Sources

Sources for Posterior Uveitis

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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