MCID: PST053
MIFTS: 45

Postherpetic Neuralgia

Categories: Neuronal diseases, Skin diseases

Aliases & Classifications for Postherpetic Neuralgia

MalaCards integrated aliases for Postherpetic Neuralgia:

Name: Postherpetic Neuralgia 55 38 74

Classifications:



External Ids:

KEGG 38 H01624
UMLS 74 C0032768

Summaries for Postherpetic Neuralgia

NINDS : 55 Shingles (herpes zoster) is an outbreak of rash or blisters on the skin that is caused by the same virus that causes chickenpox — the varicella-zoster virus. The first sign of shingles is often burning or tingling pain (which can be severe), or sometimes numbness or itch,generally on one side of the body. After several days or a week, a rash of fluid-filled blisters, similar to chickenpox, appears in one area on one side of the body. Shingles pain can be mild or intense.  Some people have mostly itching; some feel pain from the gentlest touch or breeze.  The most common location for shingles is a band, called a dermatome, spanning one side of the trunk around the waistline. Anyone who has had chickenpox is at risk for shingles.  Scientists think that some of the virus particles from the original exposure to the varicella-zoster virus,leave the skin blisters and move into the nervous system.  When the varicella-zoster virus reactivates, the virus moves back down the long nerve fibers that extend from the sensory cell bodies to the skin.  The viruses multiply, the tell-tale rash erupts, and the person now has shingles.

MalaCards based summary : Postherpetic Neuralgia is related to herpes zoster and neuropathy, and has symptoms including sciatica and neuralgia. An important gene associated with Postherpetic Neuralgia is HLA-B (Major Histocompatibility Complex, Class I, B), and among its related pathways/superpathways are Class I MHC mediated antigen processing and presentation and Cytokine Signaling in Immune system. The drugs Etoricoxib and Acyclovir have been mentioned in the context of this disorder. Affiliated tissues include skin, brain and liver, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Wikipedia : 77 Postherpetic neuralgia (PHN) is neuropathic pain which occurs due to damage to a peripheral nerve caused... more...

Related Diseases for Postherpetic Neuralgia

Diseases related to Postherpetic Neuralgia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 87)
# Related Disease Score Top Affiliating Genes
1 herpes zoster 32.6 HLA-A HLA-B
2 neuropathy 10.7
3 peripheral nervous system disease 10.6
4 diabetic neuropathy 10.5
5 herpes zoster ophthalmicus 10.4
6 trigeminal neuralgia 10.3
7 chickenpox 10.3
8 polyneuropathy 10.2
9 peptic ulcer disease 10.2
10 pain - chronic 10.2
11 rheumatoid arthritis 10.0
12 galactorrhea 10.0
13 coronary heart disease 1 10.0
14 anxiety 10.0
15 arthritis 10.0
16 brain injury 10.0
17 chronic kidney failure 10.0
18 keratopathy 10.0
19 spinal cord injury 10.0
20 traumatic brain injury 10.0
21 epidural abscess 10.0
22 heart disease 10.0
23 horner's syndrome 10.0
24 diabetic polyneuropathy 10.0
25 dermatitis 10.0
26 contact dermatitis 10.0
27 vestibular disease 10.0
28 radiculopathy 10.0
29 kidney disease 10.0
30 spondylitis 10.0
31 axonal neuropathy 10.0
32 herpes simplex 10.0
33 subacute delirium 10.0
34 rere-related disorders 10.0
35 broken heart syndrome 10.0
36 fibromyalgia 10.0
37 myoclonus 10.0
38 headache 10.0
39 neurotrophic keratopathy 10.0
40 echinococcosis 10.0 HLA-B HLA-DRB1
41 idiopathic inflammatory myopathy 10.0 HLA-B HLA-DRB1
42 acute disseminated encephalomyelitis 10.0 HLA-B HLA-DRB1
43 hemorrhagic fever with renal syndrome 10.0 HLA-B HLA-DRB1
44 rheumatic heart disease 10.0 HLA-B HLA-DRB1
45 sclerosing cholangitis 9.9 HLA-B HLA-DRB1
46 cholangitis 9.9 HLA-B HLA-DRB1
47 pure red-cell aplasia 9.9 HLA-A HLA-DRB1
48 dengue shock syndrome 9.9 HLA-A HLA-DRB1
49 palindromic rheumatism 9.9 HLA-A HLA-DRB1
50 rheumatic disease 9.9 HLA-B HLA-DRB1

Graphical network of the top 20 diseases related to Postherpetic Neuralgia:



Diseases related to Postherpetic Neuralgia

Symptoms & Phenotypes for Postherpetic Neuralgia

UMLS symptoms related to Postherpetic Neuralgia:


sciatica, neuralgia

GenomeRNAi Phenotypes related to Postherpetic Neuralgia according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-103 10.53 HLA-A HLA-B
2 Increased shRNA abundance (Z-score > 2) GR00366-A-110 10.53 HLA-A HLA-B
3 Increased shRNA abundance (Z-score > 2) GR00366-A-118 10.53 HLA-A HLA-B
4 Increased shRNA abundance (Z-score > 2) GR00366-A-156 10.53 HLA-A HLA-B
5 Increased shRNA abundance (Z-score > 2) GR00366-A-178 10.53 HLA-A HLA-B
6 Increased shRNA abundance (Z-score > 2) GR00366-A-19 10.53 HLA-A HLA-B
7 Increased shRNA abundance (Z-score > 2) GR00366-A-31 10.53 HLA-A HLA-B
8 Increased shRNA abundance (Z-score > 2) GR00366-A-7 10.53 HLA-A HLA-B
9 Increased shRNA abundance (Z-score > 2) GR00366-A-74 10.53 HLA-A HLA-B

Drugs & Therapeutics for Postherpetic Neuralgia

Drugs for Postherpetic Neuralgia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 168)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Etoricoxib Approved, Investigational Phase 4,Phase 2 202409-33-4 123619
2
Acyclovir Approved Phase 4 59277-89-3 2022
3
Foscarnet Approved Phase 4 63585-09-1, 4428-95-9 3415
4
Pregabalin Approved, Illicit, Investigational Phase 4,Phase 3,Phase 2,Phase 1 148553-50-8 5486971
5
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 137-58-6 3676
6
Acetylcholine Approved, Investigational Phase 4,Phase 2 51-84-3 187
7
Capsaicin Approved Phase 4,Phase 3,Phase 2,Phase 1 404-86-4 1548943
8
Gabapentin Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 60142-96-3 3446
9
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
10
Oxcarbazepine Approved Phase 4 28721-07-5 34312
11
Acetaminophen Approved Phase 4 103-90-2 1983
12
Furosemide Approved, Vet_approved Phase 4 54-31-9 3440
13
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
14
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 2713 9552079
15
Bupivacaine Approved, Investigational Phase 4,Phase 2 2180-92-9, 38396-39-3 2474
16
Calcium Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1 7440-70-2 271
17
Phosphonoacetic Acid Experimental Phase 4 4408-78-0 546
18 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
19 Anti-Inflammatory Agents Phase 4,Phase 2,Phase 1,Not Applicable
20 Cyclooxygenase Inhibitors Phase 4,Phase 2,Phase 1,Not Applicable
21 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 2,Phase 1,Not Applicable
22 Cyclooxygenase 2 Inhibitors Phase 4,Phase 2
23 Analgesics Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
24 Antirheumatic Agents Phase 4,Phase 2,Phase 1,Not Applicable
25 Analgesics, Non-Narcotic Phase 4,Phase 2,Phase 1,Not Applicable
26 Anti-Retroviral Agents Phase 4
27 Reverse Transcriptase Inhibitors Phase 4
28 Nucleic Acid Synthesis Inhibitors Phase 4,Not Applicable
29 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Not Applicable
30 Antiviral Agents Phase 4,Phase 3,Phase 2,Not Applicable
31 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
32 Psychotropic Drugs Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
33 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
34 calcium channel blockers Phase 4,Phase 3,Phase 2,Phase 1
35 Anti-Anxiety Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
36 Calcium, Dietary Phase 4,Phase 3,Phase 2,Phase 1
37 Anticonvulsants Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
38 Tranquilizing Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
39 Diuretics, Potassium Sparing Phase 4,Phase 3,Phase 2,Not Applicable
40 Anesthetics Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
41 Anesthetics, Local Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
42 Anti-Arrhythmia Agents Phase 4,Phase 3,Phase 2,Not Applicable
43 Sodium Channel Blockers Phase 4,Phase 3,Phase 2,Not Applicable
44 Analgesics, Opioid Phase 4,Phase 2,Phase 3,Not Applicable
45 Narcotics Phase 4,Phase 2,Phase 3,Not Applicable
46 Botulinum Toxins, Type A Phase 4,Phase 2
47 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
48 Acetylcholine Release Inhibitors Phase 4,Phase 2
49 Cholinergic Agents Phase 4,Phase 2
50 abobotulinumtoxinA Phase 4,Phase 2

Interventional clinical trials:

(show top 50) (show all 205)
# Name Status NCT ID Phase Drugs
1 Evaluation of the Efficacy, Tolerability and Safety of Etoricoxib (Arcoxia) in Patients With Neuropathic Pain Unknown status NCT01264237 Phase 4 Etoricoxib;Placebo
2 Efficacy and Safety of Foscarnet Sodium and Sodium Chloride Injection in Patients With Herpes Zoster Unknown status NCT02151240 Phase 4 Foscarnet Sodium;Acyclovir
3 Pregabalin for Treatment of Patients With Postherpetic Neuralgia (PHN) Completed NCT01455428 Phase 4 Lyrica (pregabalin);Placebo
4 A Study of the Efficacy and Safety of Pregabalin for the Treatment of Diabetic Peripheral Neuropathy or Postherpetic Neuralgia Completed NCT00629681 Phase 4 Pregabalin
5 Study of Pregabalin Therapy for Pain Relief in Subjects With Post-Herpetic Neuralgia Completed NCT00159666 Phase 4 pregabalin
6 A Study of the Effectiveness And Safety Of Lidoderm® As Add-On Treatment in Patients With Postherpetic Neuralgia, Diabetic Neuropathy, or Low Back Pain Completed NCT00904020 Phase 4 Lidoderm
7 Pregabalin Treatment Of Peripheral Neuropathic Pain Associated With Diabetic Peripheral NeP (DPN), Postherpetic Neuralgia (PHN), HIV-related NeP (HIV), and Chemotherapy Induced NeP Completed NCT00407511 Phase 4 Pregabalin
8 Efficacy Study of Botox to Treat Neuropathic Pain Completed NCT00527202 Phase 4 botulinum toxin A and saline
9 A Study to Compare QUTENZA With Pregabalin for the Treatment of Peripheral Neuropathic Pain (PNP) After 8 Weeks of Treatment Completed NCT01713426 Phase 4 Qutenza;Pregabalin
10 Acupuncture in Herpes Zoster Neuralgia (ACUZoster) Completed NCT00885586 Phase 4 gabapentine
11 Botulinum Toxin in Peripheral Neuropathic Pain Completed NCT01251211 Phase 4 botulinum toxin type A
12 LPHP-Philos-PHN Conservative Treatment Completed NCT00205959 Phase 4
13 A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions Completed NCT00904202 Phase 4 Placebo Capsules + Placebo Patch;Placebo capsules + Lidoderm®;Gabapentin + Placebo;Gabapentin + Lidoderm®;Gabapentin 300 mg capsules 1800 mg/day + placebo patch;Gabapentin 1800 mg/day + Lidoderm patch
14 Method of Pre-treatment for Application of QUTENZA Capsaicin 8% Patch Completed NCT01416116 Phase 4 QUTENZA;Lidocaine;Tramadol
15 Oxcarbazepine for the Treatment of Chronic Peripheral Neuropathic Pain Completed NCT01302275 Phase 4 Oxcarbazepine
16 Early Diuresis Following Colorectal Surgery Completed NCT02351934 Phase 4 Furosemide;Celecoxib;Gabapentin
17 Dressing: Frequency of Change and Evaluation of an Antiseptic-Impregnated Catheter Dressing in ICU Patients Completed NCT00417235 Phase 4
18 Efficacy of Pregabalin for the Treatment of Acute Herpetic Neuralgia Recruiting NCT03809702 Phase 4 Pregabalin;Placebo
19 Gabapentin for Pain Management During Dilation and Evacuation Recruiting NCT03635905 Phase 4 Gabapentin;Placebo
20 (SGB) in Men Treated for Prostate Cancer Improve Hot Flashes Not yet recruiting NCT03796195 Phase 4 .5% Bupivacaine
21 PRedictive Factors and Changes From Treatment in iPCV Versus CSR Versus nAMD With afLibercept Not yet recruiting NCT02681783 Phase 4 aflibercept
22 Pilot Study Of Pregabalin And Prediction Of Treatment Response In Patients With Postherpetic Neuralgia Terminated NCT01603394 Phase 4 pregabalin
23 Preemptive Analgesia Following Uterine Artery Embolization Terminated NCT01555073 Phase 4 pregabalin/celecoxib;pregabalin/placebo;celecoxib/placebo;Placebo group
24 Efficacy, Safety, Tolerability and Pharmacokinetics of Concomitant Administration of Tramadol With Duloxetine or Pregabalin Withdrawn NCT01116531 Phase 4 Tramadol;Duloxetine;Pregabalin
25 Efficacy and Safety of Pregabalin Sustained Release Tablet for Postherpetic Neuralgia Unknown status NCT02868801 Phase 3 Placebo;Pregabalin SR tablet 165mg/day;Pregabalin SR tablet 330mg/day;Pregabalin SR tablet 660mg/day
26 Study of PHN131 in Patients After Surgery Unknown status NCT02193620 Phase 2, Phase 3 PHN131 soft capsule with Nalbuphine HCl 60 mg/cap;Placebo soft capsules;Dicofenac
27 Effect of Opioids in Neuropathic Pain in Postherpetic Patients Unknown status NCT01102101 Phase 3 Remifentanil
28 A Novel Non Invasive Brain Stimulation Based Treatment for Chronic Low Back Pain (CLBP) Unknown status NCT02393391 Phase 2, Phase 3
29 Methadone in Post-Herpetic Neuralgia Pain Completed NCT01752699 Phase 3 Methadone;Placebo
30 A Study With Lido-Patch and Placebo Plaster in Patients Suffering From Postherpetic Neuralgia (PHN) Completed NCT03745404 Phase 3 Lidocaine 5% medicated Plaster;Placebo Plaster
31 A Study With Lidocaine 5% Medicated Plaster in Patients Suffering From Postherpetic Neuralgia Completed NCT03765697 Phase 3 Lidocaine 5% medicated plaster
32 Safety And Efficacy Study Of Once Daily Controlled Release Pregabalin In The Treatment Of Patients With Postherpetic Neuralgia Completed NCT01270828 Phase 3 Pregabalin;placebo
33 Safety and Efficacy of Gabapentin in Postherpetic Neuralgia Completed NCT00335933 Phase 3 Gabapentin extended-release tablets
34 Safety and Efficacy of Gabapentin in Postherpetic Neuralgia Completed NCT00636636 Phase 3 Gabapentin Extended Release tablets;Placebo
35 A Confirmatory Study of Fentanyl in Participants With Post-herpetic Neuralgia, Complex Regional Pain Syndrome or Postoperative Pain Syndrome Completed NCT01008553 Phase 3 Fentanyl;Placebo
36 DS-5565 Phase III Study for Renal Impairment in Japanese Subjects Completed NCT02607280 Phase 3 DS-5565
37 Study of NGX-4010 for the Treatment of Postherpetic Neuralgia Completed NCT00300222 Phase 3 NGX-4010
38 Study of NGX-4010 for the Treatment of Postherpetic Neuralgia Completed NCT00115310 Phase 3 NGX-4010
39 To Evaluate Long-Term Safety and Efficacy of Pregabalin in Patients With Postherpetic Neuralgia. Completed NCT00150436 Phase 3 Pregabalin
40 A 13-Week, Randomized, Double-Blind, Multicenter, Placebo-Controlled Study Of Pregabalin For Postherpetic Neuralgia Completed NCT00394901 Phase 3 Placebo;Pregabalin;Pregabalin;Pregabalin
41 NGX-4010 for the Treatment of Postherpetic Neuralgia Completed NCT00061776 Phase 2, Phase 3 Capsaicin Dermal Patch
42 Efficacy, Safety and Tolerability Study of TAK-583 in Subjects With Postherpetic Neuralgia Completed NCT00377598 Phase 2, Phase 3 TAK-583;TAK-583;TAK-583;TAK-583;Placebo
43 Evaluating E2007 (Perampanel) in Patients With Painful Diabetic Neuropathy (PDN) or Post-Herpetic Neuralgia (PHN) Completed NCT00592904 Phase 2, Phase 3 E2007
44 Controlled Study of NGX-4010 for the Treatment of Postherpetic Neuralgia Completed NCT00068081 Phase 3 Capsaicin Dermal Patch
45 Efficacy and Safety of Topical Versus Systemic Treatment in Postherpetic Neuralgia and Diabetic Polyneuropathic Pain Completed NCT00414349 Phase 3 Topical analgesic;oral intake;Topical analgesic
46 A Long-Term Study To Evaluate Safety And Efficacy Of Pregabalin For Postherpetic Neuralgia Completed NCT00424372 Phase 3 pregabalin
47 Shingles Prevention Study Completed NCT00007501 Phase 3
48 Phase III Randomized Controlled Study of Morphine and Nortriptyline in the Management of Postherpetic Neuralgia Completed NCT00004390 Phase 3 desipramine;methadone;morphine;nortriptyline
49 Study to Evaluate Efficacy, Safety and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Herpes Zoster (HZ) Vaccine GSK1437173A in Adults Aged 70 Years and Older Completed NCT01165229 Phase 3
50 Study To Evaluate Efficacy, Safety And Tolerability Of Lyrica In Patients With Painful Diabetic Peripheral Neuropathy Completed NCT01332149 Phase 3 Pregabalin;Placebo matched with pregabalin

Search NIH Clinical Center for Postherpetic Neuralgia

Genetic Tests for Postherpetic Neuralgia

Anatomical Context for Postherpetic Neuralgia

MalaCards organs/tissues related to Postherpetic Neuralgia:

42
Skin, Brain, Liver, Spinal Cord, Testes, Endothelial, Prostate

Publications for Postherpetic Neuralgia

Articles related to Postherpetic Neuralgia:

(show top 50) (show all 788)
# Title Authors Year
1
The Economic Burden and Impact on Quality of Life of Herpes Zoster and Postherpetic Neuralgia in Individuals Aged 50 Years or Older in Italy. ( 30793003 )
2019
2
Altered gray matter volume in patients with herpes zoster and postherpetic neuralgia. ( 30799946 )
2019
3
Premedication With Gabapentin Significantly Reduces the Risk of Postherpetic Neuralgia in Patients With Neuropathy. ( 30718068 )
2019
4
Bidirectional alterations in ALFF across slow-5 and slow-4 frequencies in the brains of postherpetic neuralgia patients. ( 30588078 )
2019
5
Sleep shortage is associated with postherpetic neuralgia development through hyperesthesia and acute pain intensity: a community-based prospective cohort study. ( 30659740 )
2019
6
Response to Transforaminal Epidural Block as a Useful Predictive Factor of Postherpetic Neuralgia. ( 30866567 )
2019
7
CT-Guided Stellate Ganglion Pulsed Radiofrequency Stimulation for Facial and Upper Limb Postherpetic Neuralgia. ( 30906243 )
2019
8
Mirogabalin for the management of postherpetic neuralgia: a randomized, double-blind, placebo-controlled phase 3 study in Asian patients. ( 30913164 )
2019
9
Associations of Perceived Mental Stress, Sense of Purpose in Life, and Negative Life Events With the Risk of Incident Herpes Zoster and Postherpetic Neuralgia: The SHEZ Study. ( 29036443 )
2018
10
Epidemiology and long-term disease burden of herpes zoster and postherpetic neuralgia in Taiwan: a population-based, propensity score-matched cohort study. ( 29554872 )
2018
11
Sensory symptom profiles differ between trigeminal and thoracolumbar postherpetic neuralgia. ( 29430564 )
2018
12
Usefulness of Inflammatory Markers for the Prediction of Postherpetic Neuralgia in Patients with Acute Herpes Zoster. ( 29606812 )
2018
13
Herpes zoster chronification to postherpetic neuralgia induces brain activity and grey matter volume change. ( 29423004 )
2018
14
Effect of Tetrodotoxin Pellets in a Rat Model of Postherpetic Neuralgia. ( 29874779 )
2018
15
Effectiveness of continuous epidural analgesia on acute herpes zoster and postherpetic neuralgia: A retrospective study. ( 29384888 )
2018
16
Impact of postherpetic neuralgia: A six year population-based analysis on people aged 50 years or older. ( 29742472 )
2018
17
Pecs II block for intractable postherpetic neuralgia. ( 29696382 )
2018
18
Efficacy of Pain Relief in Different Postherpetic Neuralgia Therapies: A Network Meta-Analysis. ( 29357328 )
2018
19
Treatment of Postherpetic Neuralgia With Intravenous Administration of Zinc Sulfate: A Case Report. ( 29634548 )
2018
20
Neurotrophic Keratopathy after Trigeminal Nerve Block for Treatment of Postherpetic Neuralgia. ( 29955409 )
2018
21
Combined therapy of pulsed radiofrequency and nerve block in postherpetic neuralgia patients: a randomized clinical trial. ( 29888123 )
2018
22
Incidence and costs of herpes zoster and postherpetic neuralgia in German adults aged a8Y50 years: A prospective study. ( 29428228 )
2018
23
The Analgesic and Emotional Response to Intravenous Lidocaine Infusion in the Treatment of Postherpetic Neuralgia: A Randomized, Double-Blinded, Placebo-Controlled Study. ( 29698250 )
2018
24
Altered functional connectivity density in patients with herpes zoster and postherpetic neuralgia. ( 29740216 )
2018
25
Postherpetic Neuralgia ( 29630250 )
2018
26
Acute pain and postherpetic neuralgia related to Varicella zoster virus reactivation: Comparison between typical herpes zoster and zoster sine herpete. ( 30179265 )
2018
27
Impact of herpes zoster and postherpetic neuralgia on the quality of life of Germans aged 50 or above. ( 30285731 )
2018
28
Corticosteroids for Preventing Postherpetic Neuralgia After Herpes Zoster Infection. ( 30421477 )
2018
29
Antiviral Medications for the Prevention of Postherpetic Neuralgia After Herpes Zoster Infection. ( 30421565 )
2018
30
Somatosensory profiles in acute herpes zoster and predictors of postherpetic neuralgia. ( 30585985 )
2018
31
Rethinking the causes of pain in herpes zoster and postherpetic neuralgia: the ectopic pacemaker hypothesis. ( 30706041 )
2018
32
Ultrasound-guided Pulsed Radiofrequency in the Management of Thoracic Postherpetic Neuralgia: A Randomized, Double-blinded, Controlled Trial. ( 29757758 )
2018
33
A Meta-Analysis of Therapeutic Efficacy and Safety of Gabapentin in the Treatment of Postherpetic Neuralgia from Randomized Controlled Trials. ( 30069477 )
2018
34
Acupuncture for postherpetic neuralgia: Systematic review and meta-analysis. ( 30142834 )
2018
35
The effect and safety of ozone autohemotherapy combined with pharmacological therapy in postherpetic neuralgia. ( 30214273 )
2018
36
Comparison of the efficacy and safety of pregabalin for postherpetic neuralgia in Chinese and international patients. ( 30214280 )
2018
37
Gasserian ganglion injected with Adriamycin successfully relieves intractable trigeminal nerve postherpetic neuralgia for an elderly patient: A case report. ( 30235706 )
2018
38
Up-date on Clinical Management of Postherpetic Neuralgia and Mechanism-Based Treatment: New Options in Therapy. ( 30247597 )
2018
39
Modalities in managing postherpetic neuralgia. ( 30310548 )
2018
40
Modulation of prefrontal connectivity in postherpetic neuralgia patients with chronic pain: a resting-state functional magnetic resonance-imaging study. ( 30323648 )
2018
41
Rapid-onset hyponatremia and delirium following duloxetine treatment for postherpetic neuralgia: Case report and literature review. ( 30431592 )
2018
42
Clinical observations on selective dorsal root ganglion pulsed radiofrequency lesioning combined with gabapentin in the treatment of postherpetic neuralgia. ( 30504569 )
2018
43
Selective dorsal root ganglion pulsed radiofrequency lesioning combined with gabapentin in the treatment of postherpetic neuralgia: The unanswered questions. ( 30504570 )
2018
44
Dynamic of the somatosensory system in postherpetic neuralgia. ( 30706032 )
2018
45
Subcutaneous Injection of Botulinum Toxin-A in Postherpetic Neuralgia During Pregnancy. ( 29184352 )
2017
46
Subcutaneous Injection of Triamcinolone and Lidocaine to Prevent Postherpetic Neuralgia. ( 28727702 )
2017
47
Glucocorticoids - Efficient analgesics against postherpetic neuralgia? ( 28850413 )
2017
48
White matter microstructure degenerates in patients with postherpetic neuralgia. ( 28729077 )
2017
49
Herpes Zoster and Postherpetic Neuralgia: Prevention and Management. ( 29431387 )
2017
50
Effect of Concomitant Pain Medications on Response to Pregabalin in Patients with Postherpetic Neuralgia or Spinal Cord Injury-Related Neuropathic Pain. ( 28072797 )
2017

Variations for Postherpetic Neuralgia

Expression for Postherpetic Neuralgia

Search GEO for disease gene expression data for Postherpetic Neuralgia.

Pathways for Postherpetic Neuralgia

Pathways related to Postherpetic Neuralgia according to GeneCards Suite gene sharing:

(show all 18)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.9 HLA-A HLA-B HLA-DRB1
2
Show member pathways
12.81 HLA-A HLA-B HLA-DRB1
3
Show member pathways
12.44 HLA-A HLA-B HLA-DRB1
4
Show member pathways
12.32 HLA-A HLA-B HLA-DRB1
5
Show member pathways
12.05 HLA-A HLA-B
6
Show member pathways
12.03 HLA-A HLA-B HLA-DRB1
7
Show member pathways
12.01 HLA-A HLA-B
8 11.95 HLA-A HLA-B
9
Show member pathways
11.92 HLA-A HLA-B HLA-DRB1
10 11.84 HLA-A HLA-B
11 11.71 HLA-A HLA-B
12 11.67 HLA-A HLA-B HLA-DRB1
13 11.63 HLA-A HLA-B
14
Show member pathways
11.53 HLA-A HLA-DRB1
15
Show member pathways
11.49 HLA-A HLA-DRB1
16 11.31 HLA-A HLA-B HLA-DRB1
17 10.96 HLA-A HLA-B HLA-DRB1
18 10.72 HLA-A HLA-B

GO Terms for Postherpetic Neuralgia

Cellular components related to Postherpetic Neuralgia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum GO:0005783 9.65 HLA-A HLA-B HLA-DRB1
2 Golgi apparatus GO:0005794 9.63 HLA-A HLA-B HLA-DRB1
3 cell surface GO:0009986 9.5 HLA-A HLA-B HLA-DRB1
4 early endosome membrane GO:0031901 9.43 HLA-A HLA-B
5 Golgi membrane GO:0000139 9.43 HLA-A HLA-B HLA-DRB1
6 recycling endosome membrane GO:0055038 9.4 HLA-A HLA-B
7 phagocytic vesicle membrane GO:0030670 9.37 HLA-A HLA-B
8 MHC class I protein complex GO:0042612 9.16 HLA-A HLA-B
9 ER to Golgi transport vesicle membrane GO:0012507 9.13 HLA-A HLA-B HLA-DRB1
10 integral component of lumenal side of endoplasmic reticulum membrane GO:0071556 8.8 HLA-A HLA-B HLA-DRB1

Biological processes related to Postherpetic Neuralgia according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 immune system process GO:0002376 9.65 HLA-A HLA-B HLA-DRB1
2 immune response GO:0006955 9.63 HLA-A HLA-B HLA-DRB1
3 regulation of immune response GO:0050776 9.51 HLA-A HLA-B
4 type I interferon signaling pathway GO:0060337 9.49 HLA-A HLA-B
5 antigen processing and presentation of peptide antigen via MHC class I GO:0002474 9.43 HLA-A HLA-B
6 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent GO:0002479 9.4 HLA-A HLA-B
7 positive regulation of T cell mediated cytotoxicity GO:0001916 9.37 HLA-A HLA-B
8 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent GO:0002480 9.32 HLA-A HLA-B
9 antigen processing and presentation of endogenous peptide antigen via MHC class Ib GO:0002476 9.26 HLA-A HLA-B
10 protection from natural killer cell mediated cytotoxicity GO:0042270 9.16 HLA-A HLA-B
11 interferon-gamma-mediated signaling pathway GO:0060333 9.13 HLA-A HLA-B HLA-DRB1
12 antigen processing and presentation GO:0019882 8.8 HLA-A HLA-B HLA-DRB1

Molecular functions related to Postherpetic Neuralgia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptide antigen binding GO:0042605 8.8 HLA-A HLA-B HLA-DRB1

Sources for Postherpetic Neuralgia

3 CDC
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