MCID: PST109
MIFTS: 25

Postinfectious Encephalitis

Categories: Immune diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Postinfectious Encephalitis

MalaCards integrated aliases for Postinfectious Encephalitis:

Name: Postinfectious Encephalitis 12 58 15
Postinfective Encephalitis 12
Secondary Encephalitis 12

Classifications:

Orphanet: 58  
Rare neurological diseases


External Ids:

Disease Ontology 12 DOID:10993
UMLS via Orphanet 72 C0393459
Orphanet 58 ORPHA98253

Summaries for Postinfectious Encephalitis

Disease Ontology : 12 An encephalitis that is characterized by the immune system mistakenly attacking healthy cells in the brain instead of attacking only the cells causing the infection, often occuring two to three weeks after the initial infection.

MalaCards based summary : Postinfectious Encephalitis, also known as postinfective encephalitis, is related to acute disseminated encephalomyelitis and encephalitis. An important gene associated with Postinfectious Encephalitis is OOSP2 (Oocyte Secreted Protein 2), and among its related pathways/superpathways are Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions and IgA-Producing B Cells in the Intestine. Affiliated tissues include brain.

Related Diseases for Postinfectious Encephalitis

Diseases related to Postinfectious Encephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 45)
# Related Disease Score Top Affiliating Genes
1 acute disseminated encephalomyelitis 30.1 MBP LGI1 CNTNAP2
2 encephalitis 10.4
3 cerebellopontine angle meningioma 10.2 LGI1 CNTNAP2
4 autoimmune encephalitis 10.2 LGI1 CNTNAP2
5 dissociative amnesia 10.2 LGI1 CNTNAP2
6 autosomal dominant epilepsy with auditory features 10.2 LGI1 CNTNAP2
7 la crosse encephalitis 10.2 LGI1 CNTNAP2
8 von economo's disease 10.2 LGI1 CNTNAP2
9 anterograde amnesia 10.2 LGI1 CNTNAP2
10 mutism 10.2 LGI1 CNTNAP2
11 lingual-facial-buccal dyskinesia 10.2 LGI1 CNTNAP2
12 stiff-person syndrome 10.2 LGI1 CNTNAP2
13 limbic encephalitis 10.2 LGI1 CNTNAP2
14 amnestic disorder 10.1 LGI1 CNTNAP2
15 polyradiculopathy 10.1 MBP LGI1
16 tertiary neurosyphilis 10.1 CXCL13 CCL15
17 color agnosia 10.1 MBP CNTNAP2
18 asymptomatic neurosyphilis 10.1 CXCL13 CCL15
19 thymus gland disease 10.1 LGI1 CNTNAP2
20 epilepsy, familial temporal lobe, 1 10.1 LGI1 CNTNAP2
21 thymus cancer 10.0 LGI1 CNTNAP2
22 dysgammaglobulinemia 10.0 SLAMF1 MBP
23 viral encephalitis 10.0 MBP LGI1
24 meningovascular neurosyphilis 10.0 MBP CXCL13
25 subacute sclerosing panencephalitis 10.0 SLAMF1 MBP
26 autoimmune disease of peripheral nervous system 9.9 MBP LGI1 CNTNAP2
27 spinal cord disease 9.9 MBP LGI1 CNTNAP2
28 encephalomalacia 9.9 MBP GALC
29 acute hemorrhagic leukoencephalitis 9.9
30 west nile virus 9.9
31 mumps 9.9
32 diphtheria 9.9
33 optic neuritis 9.9
34 neuritis 9.9
35 toxic encephalopathy 9.9
36 herpes simplex 9.9
37 chickenpox 9.9
38 encephalopathy 9.9
39 niemann-pick disease, type a 9.9 MBP GALC
40 canavan disease 9.8 MBP GALC
41 leukoencephalopathy, hereditary diffuse, with spheroids 9.8 MBP GALC
42 neuromyelitis optica 9.8 MBP CXCL13
43 osteomyelitis 9.7
44 krabbe disease 9.7 MBP GALC
45 sphingolipidosis 9.6 MBP GALC

Graphical network of the top 20 diseases related to Postinfectious Encephalitis:



Diseases related to Postinfectious Encephalitis

Symptoms & Phenotypes for Postinfectious Encephalitis

Drugs & Therapeutics for Postinfectious Encephalitis

Search Clinical Trials , NIH Clinical Center for Postinfectious Encephalitis

Genetic Tests for Postinfectious Encephalitis

Anatomical Context for Postinfectious Encephalitis

MalaCards organs/tissues related to Postinfectious Encephalitis:

40
Brain

Publications for Postinfectious Encephalitis

Articles related to Postinfectious Encephalitis:

(show all 47)
# Title Authors PMID Year
1
What Is Your Diagnosis? Bacterial osteomyelitis with secondary encephalitis. 61
26684089 2016
2
[A case of rubella encephalitis presenting as clinically mild encephalitis/encephalopathy with a reversible splenial lesion]. 61
25142541 2014
3
Expanding the spectrum of MERS type 2 lesions, a particular form of encephalitis. 61
23337007 2013
4
Acute viral encephalitis. 61
23622326 2013
5
Encephalitis and postinfectious encephalitis. 61
23221841 2012
6
[Diagnostic and therapeutic scheme of autoimmune mediated encephalitis/encephalopathy]. 61
23196437 2012
7
[Antiviral drugs]. 61
21400846 2011
8
Epilepsy: an anticipatory presentation of pediatric Wegener's granulomatosis. 61
20682204 2010
9
Update on investigation and management of postinfectious encephalitis. 61
20442573 2010
10
Acute disseminated encephalomyelitis. 61
18765104 2008
11
Pre- and post-encephalitic neuropsychological profile of a 7-year-old girl. 61
17676533 2007
12
Monofocal acute inflammatory demyelination manifesting as open ring sign. Case report. 61
16861830 2006
13
[Newly discovered human herpesviruses: pathogenesis and treatments for central nervous system infection due to HHV-6]. 61
15651311 2004
14
Postinfectious encephalitis (21 cases appended). 61
12875731 2003
15
[Movement disorders in adult-onset measles encephalitis]. 61
12590379 2003
16
Cerebellar ataxia as the presenting manifestation of Lyme disease. 61
12075773 2002
17
Postinfectious encephalitis: a coregistered SPECT and magnetic resonance imaging study. 61
11786745 2002
18
The spectrum of postinfectious encephalomyelitis. 61
11226729 2001
19
[Acute disseminated encephalomyelitis in childhood. Report of 10 cases]. 61
11346819 2001
20
[Benign encephalitis of the brain stem]. 61
11333391 2001
21
[Postinfectious encephalitis]. 61
10201127 1999
22
[Rubella virus]. 61
9103885 1997
23
Neurological aspects of rubella virus infection. 61
9450233 1997
24
Measles virus in the brain. 61
9323433 1997
25
Advantage of polymerase chain reaction in the diagnosis of herpes simplex encephalitis: presentation of 5 atypical cases. 61
9255880 1997
26
Serial magnetic resonance imaging in children with postinfectious encephalitis. 61
8980844 1996
27
Serial magnetic resonance imaging in post-infectious focal encephalitis due to influenza virus. 61
7561951 1995
28
[Encephalitis in adults]. 61
8029684 1994
29
Magnetic resonance imaging in a case of mumps postinfectious encephalitis with asymptomatic optic neuritis. 61
1959539 1991
30
Postinfectious encephalitis in two siblings. 61
1665769 1991
31
50 years ago from the Journal of the Connecticut State Medical Society. 1940. Further studies in the therapy of acute anterior poliomyelitis. 61
2178865 1990
32
Postinfectious encephalitis with multifocal white matter lesions. 61
2779748 1989
33
[Intracranial pressure in comatose meningitis and encephalitis in children]. 61
3186425 1988
34
Interferon gamma in acute and subacute encephalitis. 61
2827836 1988
35
Soluble IL-2 receptors in acute and subacute encephalitis. 61
3122647 1987
36
Hemichorea associated with varicella-zoster reinfection and endocarditis. A case report. 61
2992991 1985
37
Cellular immune responses during complicated and uncomplicated measles virus infections of man. 61
6230187 1984
38
Varicella in immunocompromised children. Incidence of abdominal pain and organ involvement. 61
6613954 1983
39
Postinfectious leukoencephalitis complicating Mycoplasma pneumoniae infection. 61
6824440 1983
40
Postvaccinal encephalomyelitis without cutaneous vaccination reaction. 61
34358 1979
41
[A supplement of the neuropathology of the acute encephalopathies in childhood, especially about the relation of acute toxic encephalopathy and Ekiri, Ekiri--like syndrome. IV. The neuropathology of the postvaccinal and postinfectious encephalitis in children under two years of age (author's transl)]. 61
10594 1976
42
[Postinfectious encephalitis (encephalomyelitis) in the case histories of the clinic for nervous, mental and infectious diseases in Skoplje during the years 1961-1970]. 61
4663194 1972
43
[Comparative characteristics of electroencephalograms in primary and secondary encephalitis]. 61
4944286 1971
44
[Steroid hormonal therapy in infectious secondary encephalitis]. 61
4390737 1968
45
[Anti-inflammatory, anticonvulsant and antibiotic therapy of secondary encephalitis]. 61
4380879 1966
46
[Postinfectious secondary encephalitis and encephalopathy; clinical aspects and neuropathology with special reference to experimental animal research]. 61
13331004 1956
47
PUBLIC health. Statistics for 1950; Scotland. Infectious diseases in England and Wales. Postinfectious encephalitis. Campaign against diphtheria. 61
14825838 1951

Variations for Postinfectious Encephalitis

Expression for Postinfectious Encephalitis

Search GEO for disease gene expression data for Postinfectious Encephalitis.

Pathways for Postinfectious Encephalitis

Pathways related to Postinfectious Encephalitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.13 CXCL13 CCL15 CCL13
2 10.78 SLAMF1 CXCL13

GO Terms for Postinfectious Encephalitis

Cellular components related to Postinfectious Encephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.1 SLAMF1 OOSP2 LGI1 CXCL13 CCL15 CCL13

Biological processes related to Postinfectious Encephalitis according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.61 CXCL13 CCL15 CCL13
2 immune response GO:0006955 9.56 MBP CXCL13 CCL15 CCL13
3 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.54 SLAMF1 CCL15 CCL13
4 chemotaxis GO:0006935 9.5 CXCL13 CCL15 CCL13
5 antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 9.49 CXCL13 CCL13
6 myelination GO:0042552 9.48 MBP GALC
7 monocyte chemotaxis GO:0002548 9.46 CCL15 CCL13
8 lymphocyte chemotaxis GO:0048247 9.4 CCL15 CCL13
9 cell chemotaxis GO:0060326 9.33 CXCL13 CCL15 CCL13
10 neutrophil chemotaxis GO:0030593 9.13 CXCL13 CCL15 CCL13
11 chemokine-mediated signaling pathway GO:0070098 8.8 CXCL13 CCL15 CCL13

Molecular functions related to Postinfectious Encephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.33 CXCL13 CCL15 CCL13
2 CCR chemokine receptor binding GO:0048020 8.96 CCL15 CCL13
3 chemokine activity GO:0008009 8.8 CXCL13 CCL15 CCL13

Sources for Postinfectious Encephalitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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