MCID: PST054
MIFTS: 15

Postinfectious Encephalomyelitis

Categories: Eye diseases, Neuronal diseases

Aliases & Classifications for Postinfectious Encephalomyelitis

MalaCards integrated aliases for Postinfectious Encephalomyelitis:

Name: Postinfectious Encephalomyelitis 54 72

Classifications:



External Ids:

UMLS 72 C0751100

Summaries for Postinfectious Encephalomyelitis

NINDS : 54 Acute disseminated encephalomyelitis (ADEM) is characterized by a brief but widespread attack of inflammation in the brain and spinal cord that damages myelin – the protective covering of nerve fibers.  ADEM often follows viral or bacterial infections, or less often, vaccination for measles, mumps, or rubella.  The symptoms of ADEM appear rapidly, beginning with encephalitis-like symptoms such as fever, fatigue, headache, nausea and vomiting, and in the most severe cases, seizures and coma.  ADEM typically damages white matter (brain tissue that takes its name from the white color of myelin), leading to neurological symptoms such as visual loss (due to inflammation of the optic nerve) in one or both eyes, weakness even to the point of paralysis, and difficulty coordinating voluntary muscle movements (such as those used in walking).  ADEM is sometimes misdiagnosed as a severe first attack of multiple sclerosis (MS), since the symptoms and the appearance of the white matter injury on brain imaging may be similar.  However, ADEM has several features which differentiate it from MS.  First, unlike MS patients, persons with ADEM will have rapid onset of fever, a history of recent infection or immunization, and some degree of impairment of consciousness, perhaps even coma; these features are not typically seen in MS.  Children are more likely than adults to have ADEM, whereas MS is a rare diagnosis in children.  In addition, ADEM usually consists of a single episode or attack of widespread myelin damage, while MS features many attacks over the course of time. Doctors will often use imaging techniques, such as MRI (magnetic resonance imaging), to search for old and new lesions (areas of damage) on the brain.  The presence of older brain lesions on MRI suggest that the condition may be MS rather than ADEM, since MS can cause brain lesions before symptoms become obvious.  In rare situations, a brain biopsy may be necessary to differentiate between ADEM and some other diseases that involve inflammation and damage to myelin.

MalaCards based summary : Postinfectious Encephalomyelitis is related to acute disseminated encephalomyelitis and demyelinating disease. Affiliated tissues include brain, eye and spinal cord.

Related Diseases for Postinfectious Encephalomyelitis

Diseases related to Postinfectious Encephalomyelitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 32)
# Related Disease Score Top Affiliating Genes
1 acute disseminated encephalomyelitis 10.3
2 demyelinating disease 10.2
3 encephalitis 10.2
4 measles 10.1
5 allergic encephalomyelitis 10.1
6 autoimmune disease 10.0
7 ocular motor apraxia 10.0
8 gastrointestinal ulceration, recurrent, with dysfunctional platelets 10.0
9 mumps 10.0
10 japanese encephalitis 10.0
11 rabies 10.0
12 neuritis 10.0
13 gastroenteritis 10.0
14 myelitis 10.0
15 central nervous system disease 10.0
16 cranial nerve palsy 10.0
17 dystonia 10.0
18 viral encephalitis 10.0
19 peptic ulcer disease 10.0
20 peptic ulcer perforation 10.0
21 appendicitis 10.0
22 influenza 10.0
23 herpes simplex 10.0
24 nervous system disease 10.0
25 rubella 10.0
26 athetosis 10.0
27 herpes simplex encephalitis 10.0
28 transverse myelitis 10.0
29 encephalopathy 10.0
30 hypotonia 10.0
31 acute transverse myelitis 10.0
32 postinfectious encephalitis 10.0

Graphical network of the top 20 diseases related to Postinfectious Encephalomyelitis:



Diseases related to Postinfectious Encephalomyelitis

Symptoms & Phenotypes for Postinfectious Encephalomyelitis

Drugs & Therapeutics for Postinfectious Encephalomyelitis

Search Clinical Trials , NIH Clinical Center for Postinfectious Encephalomyelitis

Genetic Tests for Postinfectious Encephalomyelitis

Anatomical Context for Postinfectious Encephalomyelitis

MalaCards organs/tissues related to Postinfectious Encephalomyelitis:

41
Brain, Eye, Spinal Cord, T Cells, Kidney

Publications for Postinfectious Encephalomyelitis

Articles related to Postinfectious Encephalomyelitis:

(show all 42)
# Title Authors PMID Year
1
Encephalitis associated with human herpesvirus-7 infection in an immunocompetent adult. 38
28545483 2017
2
Acute Neurological Illness in a Kidney Transplant Recipient Following Infection With Enterovirus-D68: An Emerging Infection? 38
26228743 2015
3
Severe Measles Infection: The Spectrum of Disease in 36 Critically Ill Adult Patients. 38
23982057 2013
4
Influenza-related postinfectious encephalomyelitis complicated by a perforated peptic ulcer. 38
23597530 2013
5
IVIG treatment for VZV-related acute inflammatory polyneuropathy in a child. 38
22814982 2012
6
Central brain herniation secondary to fulminant acute disseminated encephalomyelitis: implications for neurosurgical management. Case report. 38
16961146 2006
7
MRI findings from a case of fulminating adult-onset measles encephalitis. 38
16847369 2006
8
Main adult herpes virus infections of the CNS. 38
16107204 2005
9
Molecular methods for diagnosis of viral encephalitis. 38
15489354 2004
10
Postinfectious encephalomyelitis. 38
12691631 2003
11
Idiopathic Parkinson's disease(s) may follow subclinical episodes of perivenous demyelination. 38
12445523 2002
12
The spectrum of postinfectious encephalomyelitis. 38
11226729 2001
13
Postinfectious encephalomyelitis: etiologic and diagnostic trends. 38
11063080 2000
14
[Acute disseminated postinfectious encephalomyelitis]. 38
10870207 2000
15
ADEM: literature review and case report of acute psychosis presentation. 38
10669199 2000
16
Encephalitis. 38
10517930 1999
17
[Postinfectious encephalomyelitis]. 38
10088394 1999
18
Clonal expansion of T-cells in measles. 38
9840683 1998
19
Encephalitis. Identifying the specific cause is key to effective management. 38
9519034 1998
20
Acute transverse myelitis. A localized form of postinfectious encephalomyelitis. 38
9236624 1997
21
[Acute disseminated encephalomyelitis]. 38
9103897 1997
22
[The pathogenesis of postinfectious encephalomyelitis and polyradiculoneuritis]. 38
9103874 1997
23
The binge eating and emotional change in a patient with postinfectious encephalomyelitis. 38
9099051 1997
24
Mycoplasma pneumoniae postinfectious encephalomyelitis with bilateral striatal necrosis. 38
8723156 1996
25
Eicosenoids Modify Experimental Allergic Encephalomyelitis. 38
11854849 1995
26
Autoimmunity caused by host cell protein-containing viruses. 38
7531273 1994
27
[Acute postinfectious encephalomyelitis. A case report]. 38
8274235 1993
28
Role of plasmapheresis in acute disseminated (postinfectious) encephalomyelitis. 38
1299654 1992
29
Steroid-dependent postvaricella encephalomyelitis. 38
2002201 1991
30
Monophasic autoimmune inflammatory diseases of the CNS and PNS. 38
1970192 1990
31
Treatment of encephalomyocarditis virus-induced central nervous system demyelination with monoclonal anti-T-cell antibodies. 38
2550666 1989
32
Postinfectious encephalomyelitis with localized basal ganglia involvement. 38
2803390 1989
33
Histocompatibility determinants in childhood postinfectious encephalomyelitis. 38
2475540 1989
34
Myelin basic protein and proteolipid protein reactivity of brain- and cerebrospinal fluid-derived T cell clones in multiple sclerosis and postinfectious encephalomyelitis. 38
2438352 1987
35
The pathogenesis of acute viral encephalitis and postinfectious encephalomyelitis. 38
3027198 1987
36
Diagnostic value of cerebrospinal fluid anti-myelin basic protein in patients with multiple sclerosis. 38
2427010 1986
37
Measles encephalomyelitis--clinical and immunologic studies. 38
6197651 1984
38
Vaccinia virus infection of the central nervous system in X-irradiated mice. 38
500184 1979
39
Postvaricella suppurative meningitis. Case reports and review of the literature. 38
474544 1979
40
Postinfectious encephalomyelitis as a sequel of herpes simplex encephalitis treated with adenine arabinoside. 38
757062 1978
41
Tonic pupils with acute ophthalmoplegic polyneuritis. 38
617578 1977
42
Possible mechanisms in the pathogenesis of "postinfectious" encephalomyelitis. 38
4332337 1971

Variations for Postinfectious Encephalomyelitis

Expression for Postinfectious Encephalomyelitis

Search GEO for disease gene expression data for Postinfectious Encephalomyelitis.

Pathways for Postinfectious Encephalomyelitis

GO Terms for Postinfectious Encephalomyelitis

Sources for Postinfectious Encephalomyelitis

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