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MCID: PST021
MIFTS: 53

Postpartum Depression

Categories: Mental diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Postpartum Depression

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MalaCards integrated aliases for Postpartum Depression:

Name: Postpartum Depression 12 43 15
Depression, Postpartum 44 73
Maternity Blues 12 73
Post-Partum Depression 76
Depression Postpartum 55
Postnatal Depression 12

Classifications:

MalaCards categories:
Anatomical: Mental diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:9478
ICD10 33 F53
MeSH 44 D019052
NCIt 50 C92852
Sources

Summaries for Postpartum Depression

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MedlinePlus : 43 Many women have the baby blues after childbirth. If you have the baby blues, you may have mood swings, feel sad, anxious or overwhelmed, have crying spells, lose your appetite, or have trouble sleeping. The baby blues most often go away within a few days or a week. The symptoms are not severe and do not need treatment. The symptoms of postpartum depression last longer and are more severe. You may also feel hopeless and worthless, and lose interest in the baby. You may have thoughts of hurting yourself or the baby. Very rarely, new mothers develop something even more serious. They may have hallucinations or try to hurt themselves or the baby. They need to get treatment right away, often in the hospital. Postpartum depression can begin anytime within the first year after childbirth. The cause is not known. Hormonal and physical changes after birth and the stress of caring for a new baby may play a role. Women who have had depression are at higher risk. If you think you have postpartum depression, tell your health care provider. Medicines, including antidepressants and talk therapy can help you get well. Dept. of Health and Human Services Office on Women's Health

MalaCards based summary : Postpartum Depression, also known as depression, postpartum, is related to depression and premenstrual tension, and has symptoms including pelvic pain and mental and behavioral signs and symptoms. An important gene associated with Postpartum Depression is CRH (Corticotropin Releasing Hormone), and among its related pathways/superpathways are cAMP signaling pathway and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. The drugs Copper and Estradiol valerate have been mentioned in the context of this disorder. Affiliated tissues include skin, thyroid and placenta, and related phenotypes are behavior/neurological and endocrine/exocrine gland

Disease Ontology : 12 An endogenous depression that involves intense, sustained and sometimes disabling depression experienced by women after giving birth.

Wikipedia : 76 Postpartum depression (PPD), also called postnatal depression, is a type of mood disorder associated... more...

Sources

Related Diseases for Postpartum Depression

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Diseases related to Postpartum Depression via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 111)
# Related Disease Score Top Affiliating Genes
1 depression 31.0 BDNF CRH HTR1A MAOA SLC6A4
2 premenstrual tension 30.0 CRH PRL
3 trigeminal neuralgia 29.9 ESR1 SLC6A4
4 anxiety 28.4 BDNF COMT CRH HTR1A MAOA SLC6A4
5 personality disorder 28.3 BDNF COMT HTR1A MAOA SLC6A4
6 schizophrenia 27.5 BDNF COMT HTR1A MAOA PRL SLC6A4
7 mood disorder 27.5 BDNF COMT CRH HTR1A MAOA SLC6A4
8 major depressive disorder 27.2 BDNF COMT CRH HTR1A MAOA PRL
9 bipolar disorder 27.0 BDNF COMT CRH HTR1A MAOA PRL
10 hypothalamic disease 10.7 CRH PRL
11 pituitary carcinoma 10.7 CRH PRL
12 nelson syndrome 10.7 CRH PRL
13 sheehan syndrome 10.7 CRH PRL
14 schizophreniform disorder 10.7 COMT PRL
15 acth-secreting pituitary adenoma 10.7 CRH PRL
16 hypothyroidism, congenital, nongoitrous, 4 10.6 PRL TPO
17 dysthymic disorder 10.5 MAOA SLC6A4
18 phobia, specific 10.5 COMT MAOA
19 adrenal cortex disease 10.5 CRH PRL
20 traumatic brain injury 10.5 BDNF COMT
21 adrenal gland disease 10.5 CRH PRL
22 pathological gambling 10.5 MAOA SLC6A4
23 alcohol abuse 10.4 BDNF PRL SLC6A4
24 fibromyalgia 10.4 COMT CRH SLC6A4
25 drug dependence 10.4 BDNF CRH SLC6A4
26 retinitis pigmentosa 20 10.4 ESR1 SLC6A4
27 atypical depressive disorder 10.4 CRH MAOA SLC6A4
28 dystonia 1, torsion, autosomal dominant 10.4 COMT MAOA
29 avoidant personality disorder 10.4 CRH MAOA
30 pervasive developmental disorder 10.3 BDNF OXTR SLC6A4
31 oppositional defiant disorder 10.3 COMT MAOA SLC6A4
32 antisocial personality disorder 10.3 COMT MAOA SLC6A4
33 substance dependence 10.2 BDNF MAOA SLC6A4
34 melancholia 10.2 CRH IER3IP1 PRL
35 autism spectrum disorder 10.2 BDNF OXTR SLC6A4
36 mammographic density 10.1 COMT ESR1 PRL
37 paraphilia disorder 10.1 MAOA PRL
38 schizoaffective disorder 10.1 BDNF COMT PRL SLC6A4
39 eating disorder 10.1 BDNF COMT CRH SLC6A4
40 breast disease 10.1 COMT ESR1 PRL
41 adenomyosis 10.1 ESR1 OXTR PRL
42 psychosexual disorder 10.1 HTR1A SLC6A4
43 separation anxiety disorder 10.1 OXTR PRL
44 pituitary-dependent cushing's disease 10.0 CRH HSD11B1 PRL
45 synucleinopathy 10.0 BDNF COMT IER3IP1
46 periodic limb movement disorder 10.0 HTR1A SLC6A4
47 paranoid schizophrenia 10.0 BDNF COMT MAOA SLC6A4
48 early-onset schizophrenia 10.0 BDNF COMT MAOA SLC6A4
49 bulimia nervosa 10.0 BDNF COMT MAOA SLC6A4
50 aging 10.0

Graphical network of the top 20 diseases related to Postpartum Depression:



Diseases related to Postpartum Depression
Sources

Symptoms & Phenotypes for Postpartum Depression

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UMLS symptoms related to Postpartum Depression:


pelvic pain, mental and behavioral signs and symptoms

MGI Mouse Phenotypes related to Postpartum Depression:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.02 CRH SLC6A4 ESR1 HSD11B1 HTR1A MAOA
2 endocrine/exocrine gland MP:0005379 9.91 CRH SLC6A4 ESR1 TPO HSD11B1 BDNF
3 homeostasis/metabolism MP:0005376 9.85 PRL CRH SLC6A4 TPO ESR1 HSD11B1
4 integument MP:0010771 9.5 PRL CRH SLC6A4 ESR1 HSD11B1 BDNF
5 nervous system MP:0003631 9.32 CRH SLC6A4 ESR1 HSD11B1 HTR1A MAOA
Sources

Drugs & Therapeutics for Postpartum Depression

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Drugs for Postpartum Depression (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 236)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Copper Approved, Investigational Phase 4,Phase 3 7440-50-8 27099
2 Estradiol valerate Approved, Investigational, Vet_approved Phase 4,Phase 2,Not Applicable 979-32-8
3
Ropivacaine Approved Phase 4,Phase 3,Phase 2,Not Applicable 84057-95-4 71273 175805
4
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 2,Not Applicable 50-28-2 5757
5
Norethindrone Approved Phase 4 68-22-4 6230
6
Oxytocin Approved, Vet_approved Phase 4,Phase 2,Not Applicable 50-56-6 439302 53477758
7
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
8
Polyestradiol phosphate Approved Phase 4,Phase 2,Not Applicable 28014-46-2
9
Sertraline Approved Phase 4,Phase 3,Phase 2,Not Applicable 79617-96-2 68617
10
Norepinephrine Approved Phase 4,Phase 3,Not Applicable 51-41-2 439260
11
Calcium Carbonate Approved, Investigational Phase 4 471-34-1
12
Citalopram Approved Phase 4,Not Applicable 59729-33-8 2771
13
Medroxyprogesterone acetate Approved, Investigational Phase 4 71-58-9
14
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
15
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
16
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
17
Hydromorphone Approved, Illicit Phase 4 466-99-9 5284570
18
Paroxetine Approved, Investigational Phase 4 61869-08-7 43815
19
Fluoxetine Approved, Vet_approved Phase 4 54910-89-3 3386
20
Fluvoxamine Approved, Investigational Phase 4 54739-18-3 3404 5324346
21
Carbetocin Approved, Investigational Phase 4 37025-55-1 71715 16681432
22 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Not Applicable
23 Serotonin Agents Phase 4,Phase 3,Phase 2,Not Applicable
24 Spermatocidal Agents Phase 4
25 Contraceptive Agents Phase 4,Phase 2,Not Applicable
26 Contraceptives, Oral Phase 4,Not Applicable
27 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Not Applicable
28 Anesthetics Phase 4,Phase 3,Phase 2,Not Applicable
29 Hormone Antagonists Phase 4,Phase 2,Not Applicable
30 Norethindrone acetate Phase 4
31 Anesthetics, Local Phase 4,Phase 3,Phase 2,Not Applicable
32 Hormones Phase 4,Phase 2,Not Applicable
33 Disinfectants Phase 4
34 Oxytocics Phase 4,Phase 2,Not Applicable
35 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Not Applicable
36 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Not Applicable
37 Estradiol 17 beta-cypionate Phase 4,Phase 2,Not Applicable
38 Estradiol 3-benzoate Phase 4,Phase 2,Not Applicable
39 Estrogens Phase 4,Phase 2,Not Applicable
40 Antidepressive Agents Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1
41 Antirheumatic Agents Phase 4,Phase 3,Not Applicable
42 Progestins Phase 4,Not Applicable
43
Medroxyprogesterone Phase 4 520-85-4 10631
44 Analgesics Phase 4,Phase 2,Phase 3,Not Applicable
45 Cholinergic Agents Phase 4,Not Applicable
46 Muscarinic Antagonists Phase 4,Not Applicable
47 Cholinergic Antagonists Phase 4,Not Applicable
48 Serotonin and Noradrenaline Reuptake Inhibitors Phase 4,Phase 3,Not Applicable
49 Serotonin Uptake Inhibitors Phase 4,Phase 3,Phase 2,Not Applicable
50 Gastrointestinal Agents Phase 4

Interventional clinical trials:

(show top 50) (show all 358)
# Name Status NCT ID Phase Drugs
1 Oral Contraceptive Ethinyl Estradiol Dose Effect on Postpartum Depression and Sexual Functioning Scales Unknown status NCT02210702 Phase 4 Ethinyl Estradiol 35mcg/Norethindrone 1mg;Ethinyl Estradiol 20mcg/Norethindrone 1mg
2 The Influence of Antenatal Classes on Pregnancy, Birth and Parenthood Unknown status NCT00323401 Phase 4
3 Escitalopram (Lexapro) for the Treatment of Postpartum Depression Completed NCT00833469 Phase 4 Escitalopram
4 Effectiveness of Supplemental Calcium in Preventing Postpartum Depression Completed NCT00228033 Phase 4 Elemental calcium (as carbonate)
5 Timing of Postpartum Depot Medroxyprogesterone Acetate Administration on Breastfeeding, Contraceptive Continuation, and Depression Completed NCT01463202 Phase 4 Depot medroxyprogesterone acetate;Depot medroxyprogesterone acetate
6 Vitamin B12 Pregnancy Supplementation Completed NCT03522428 Phase 4
7 NEOBIFI: Clinical Trial for the Prevention and/or Reduction of the Incidence of Colics in Infants Completed NCT03219931 Phase 4 Bifidobacterium breve BR03 and Bifidobacterium breve B632;Placebos
8 Low-dose Ketamine and Postpartum Depression in Parturients With Prenatal Depression Recruiting NCT03336541 Phase 4 Ketamine;Placebo
9 Effect of Tramadol in Prevention of Postpartum Depression Recruiting NCT03309163 Phase 4 Tramadol;Hydromorphone;Ropivacaine (Epidural analgesia)
10 Postpartum Perineal Pain After Obstetric Anal Sphincter Injuries Recruiting NCT03470675 Phase 4 Epidural saline + IV saline;Epidural morphine 3 mg + IV saline;Epidural morphine 3 mg + IV ketamine 0.3 mg/kg
11 Impact of Local Anesthetic Wound Infiltration on Postoperative Pain Following Cesarean Delivery Recruiting NCT02829944 Phase 4 Ropivacaine;Ketorolac;Placebo
12 Antidepressants During Pregnancy and Lactation: Pharmacokinetics and Clinical Implications Recruiting NCT01796132 Phase 4 SSRI/SNRI
13 Effect of the Uterotonic Carbetocin on Acute Post Cesarean-Section Pain Not yet recruiting NCT02642263 Phase 4 Carbetocin
14 Oxytocin Dosing at Planned Cesarean Section and Anemia Not yet recruiting NCT03361124 Phase 4 Oxytocin
15 Vaginal Estrogen on Postpartum Atrophy, Perineal Pain, and Sexual Function Not yet recruiting NCT03493126 Phase 4 Estradiol
16 Postpartum Depression: Transdermal Estradiol Versus Sertraline Terminated NCT00744328 Phase 4 Transdermal Estradiol;Sertraline
17 Outcome of Postnatal Depression Screening Using Edinburgh Postnatal Depression Scale Unknown status NCT00251342 Phase 2, Phase 3
18 Postoperative Analgesia After Caesarean Section Under ALR: TAP Block Versus Catheter Scar Infiltration Unknown status NCT02184559 Phase 3 Ropivacaine
19 A Randomized Trial of Docosahexaenoic Acid Supplementation During Pregnancy to Prevent Deep Placentation Disorders Unknown status NCT02336243 Phase 3
20 Aripiprazole and Resistant Postpartum Depression Completed NCT01386086 Phase 3 aripiprazole
21 A Study to Evaluate SAGE-547 in Patients With Severe Postpartum Depression Completed NCT02942004 Phase 3 SAGE-547;Placebo
22 A Study to Evaluate SAGE-547 in Patients With Moderate Postpartum Depression Completed NCT02942017 Phase 3 SAGE-547;Placebo
23 Identification and Therapy of Postpartum Depression Completed NCT00282776 Phase 3
24 Sertraline for the Prevention of Recurrent Postpartum Depression Completed NCT00276900 Phase 3 Sertraline
25 Functional Outcome in Postpartum Depression in Women Treated With Desvenlafaxine Completed NCT01527786 Phase 3 Desvenlafaxine
26 A Randomised Trial of Sertraline, Cognitive Behaviour Therapy & Combined Therapy for Postnatal Depression Completed NCT02122393 Phase 3 Sertraline
27 Effect of the 'Mother and Baby' Program on Well-Being Completed NCT00361478 Phase 3
28 Mother-Infant Psychoanalysis Project of Stockholm Completed NCT00923559 Phase 3
29 Does Fish Oil Prevent Depression in Pregnancy and Postpartum? Completed NCT00711971 Phase 2, Phase 3 EPA-rich fish oil supplement;DHA-rich fish oil supplement;placebo
30 Improving Health Outcomes for New Mothers and Babies Completed NCT00360204 Phase 3
31 Gestational Diabetes: Insulin or Oral Hypoglycemic Agents? Completed NCT01215331 Phase 3 Insulin;Metformin, glyburide and insulin
32 Vitamin B12 Supplementation During Pregnancy Completed NCT01795131 Phase 2, Phase 3
33 Treatment of Women After Severe Postpartum Haemorrhage Completed NCT01895205 Phase 3 Iron isomaltoside 1000;Red blood cell transfusion
34 Treatment of Women After Postpartum Haemorrhage Completed NCT01895218 Phase 3 Iron isomaltoside 1000
35 Hypnosis Antenatal Training for Childbirth (HATCh): a Randomised Controlled Trial Completed NCT00282204 Phase 2, Phase 3
36 The Synchronized Trial on Expectant Mothers With Depressive Symptoms by Omega-3 PUFAs (SYNCHRO) Completed NCT02166424 Phase 3
37 CODEPAD (Collaborative Outcomes of DEpression and Pain Associated With Delivery) Recruiting NCT03167905 Phase 2, Phase 3 Entonox;Meperidine;Ultiva;Fentanyl;Ropivacaine
38 ITM + Bupivacaine QLB vs. ITM + Sham Saline QLB for Cesarean Delivery Pain Recruiting NCT03261193 Phase 3 ITM + Sham QLB;ITM + Bupivacaine QLB
39 Dolutegravir in Pregnant HIV Mothers and Their Neonates Recruiting NCT03249181 Phase 3 Dolutegravir;Standard of Care (EFV + 2 NRTI backbone)
40 Impact of Pre-pregnancy Micronutrient Supplementation on Maternal and Child Outcomes Active, not recruiting NCT01665378 Phase 3
41 Adjunctive Use of Celecoxib in the Treatment of Bipolar Postpartum Depression Not yet recruiting NCT02726659 Phase 3 Celecoxib;Placebo
42 Oral Probiotic Supplementation in Pregnancy to Reduce Group B Streptococcus Colonization Not yet recruiting NCT03407157 Phase 3
43 Controlled Randomised Trial of Ferric Carboxymaltose and Oral Iron to Treat Postpartum Anemia Terminated NCT00929409 Phase 2, Phase 3 Ferric carboxymaltose;Ferrous sulfate tablets
44 Pilot Trial of CenteringPregnancy With Mindfulness Skills Unknown status NCT01646463 Phase 1, Phase 2
45 Evaluate SAGE-547 in Female Patients With Severe Postpartum Depression Completed NCT02285504 Phase 2 SAGE-547
46 Mom: Managing Our Mood, Part of The Family Help Program Completed NCT00795652 Phase 2
47 The Effect of Exercise on Preventing PostPartum Depression Completed NCT00961402 Phase 2
48 A Study to Evaluate SAGE-547 in Patients With Severe Postpartum Depression Completed NCT02614547 Phase 2 SAGE-547;Placebo
49 Change Your Life With Seven Sheets of Paper Completed NCT02532504 Phase 2
50 Repetitive Transcranial Magnetic Stimulation in Postpartum Depression Completed NCT01452321 Phase 2

Search NIH Clinical Center for Postpartum Depression

Cochrane evidence based reviews: depression, postpartum

Sources

Genetic Tests for Postpartum Depression

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Sources

Anatomical Context for Postpartum Depression

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MalaCards organs/tissues related to Postpartum Depression:

41
Skin, Thyroid, Placenta, Bone, Colon, Heart, Amygdala
Sources

Publications for Postpartum Depression

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Articles related to Postpartum Depression:

(show top 50) (show all 693)
# Title Authors Year
1
'Happy that someone cared'-Non-native-speaking immigrant mothers' experiences of participating in screening for postpartum depression in the Swedish child health services. ( 29804463 )
2018
2
Relationship Between Postpartum Depression and Psychological and Biological Variables in the Initial Postpartum Period. ( 29423586 )
2018
3
Postpartum Depression and Its Long-term Impact on Children: Many New Questions. ( 29387871 )
2018
4
Passive smoking and postpartum depression among Chinese women: a prospective cohort study in Tianjin, China. ( 29924720 )
2018
5
Integrating Optimal Screening, Intervention, and Referral for Postpartum Depression in Adolescents. ( 29779510 )
2018
6
Preliminary Psychometric Testing of the Postpartum Depression Predictors Inventory-Revised (PDPI-R) in Portuguese Women. ( 29327321 )
2018
7
The role of tryptophan metabolism in postpartum depression. ( 29307018 )
2018
8
Screening for Postpartum Depression in American Indian/Alaska Native Women: A Comparison of Two Instruments. ( 29889949 )
2018
9
Subconstructs of the Edinburgh Postpartum Depression Scale in a postpartum sample in Mexico City. ( 29879609 )
2018
10
Mastery, self-esteem, and optimism mediate the link between religiousness and spirituality and postpartum depression. ( 29855845 )
2018
11
Adverse Childhood Experiences and Postpartum Depression in Home Visiting Programs: Prevalence, Association, and Mediating Mechanisms. ( 29435785 )
2018
12
Postpartum depression in older women. ( 29401116 )
2018
13
Association between intrapartum epidural use and maternal postpartum depression presenting for medical care: a population-based, matched cohort study. ( 29954649 )
2018
14
Postpartum depression and vitamin D: A systematic review. ( 29393662 )
2018
15
Effectiveness of acupuncture in postpartum depression: a systematic review and meta-analysis. ( 29907576 )
2018
16
Prevalence and factors associated with postpartum depression in women from single-child families. ( 29412451 )
2018
17
Rationale, design, and baseline data for the Healthy Mom II Trial: A randomized trial examining the efficacy of exercise and wellness interventions for the prevention of postpartum depression. ( 29747048 )
2018
18
Injection of oxytocin into paraventricular nucleus reverses depressive-like behaviors in the postpartum depression rat model. ( 28889022 )
2018
19
An analysis of whether sleep disorder will result in postpartum depression. ( 29861873 )
2018
20
Anaemia and depletion of iron stores as risk factors for postpartum depression: a literature review. ( 29363366 )
2018
21
Risk factors for positive postpartum depression screen in women with private health insurance and access to care. ( 29852802 )
2018
22
Commentary on "Improvement of postpartum depression and psychosis after electroconvulsive therapy - A population-based study with a matched comparison group". ( 29908473 )
2018
23
The effectiveness of exercise-based interventions for preventing or treating postpartum depression: a systematic review and meta-analysis. ( 29882074 )
2018
24
Adverse childhood experiences and intimate partner violence during pregnancy and their association to postpartum depression. ( 29310065 )
2018
25
Gene expression profile in peripheral blood mononuclear cells of postpartum depression patients. ( 29973662 )
2018
26
Thyroid peroxidase antibodies during early gestation and the subsequent risk of first-onset postpartum depression: A prospective cohort study. ( 28850854 )
2018
27
Digital Peer-Support Platform (7Cups) as an Adjunct Treatment for Women With Postpartum Depression: Feasibility, Acceptability, and Preliminary Efficacy Study. ( 29439944 )
2018
28
Perinatal Nurses' and Midwives' Knowledge About Assessment and Management of Postpartum Depression. ( 29916523 )
2018
29
Coping strategies of women with postpartum depression symptoms in rural Ethiopia: a cross-sectional community study. ( 29422037 )
2018
30
Developing a Postpartum Depression Screening and Referral Procedure in Pediatric Primary Care. ( 29305113 )
2018
31
Postpartum depression and social support in a racially and ethnically diverse population of women. ( 29968129 )
2018
32
Peer-support intervention for postpartum depression: Participant satisfaction and program effectiveness. ( 29908406 )
2018
33
Comments on: insomnia, postpartum depression and estradiol in women after delivery. ( 29340844 )
2018
34
Postpartum depression and resilience predict parenting sense of competence in women with childhood maltreatment history. ( 29860623 )
2018
35
GABA<sub>A</sub> dysregulation as an explanatory model for late-onset postpartum depression associated with weaning and resumption of menstruation. ( 29968131 )
2018
36
Treatment of Postpartum Depression: Recommendations for the Clinician. ( 29351116 )
2018
37
Prevalence of postpartum depression and interventions utilized for its management. ( 29760762 )
2018
38
Incidence of and social-demographic and obstetric factors associated with postpartum depression: differences among ethnic Han and Kazak women of Northwestern China. ( 29404223 )
2018
39
The Relationship Between Women's Intention to Request a Labor Epidural Analgesia, Actually Delivering With Labor Epidural Analgesia, and Postpartum Depression at 6 Weeks: A Prospective Observational Study. ( 28930940 )
2017
40
Antidepressant-Like Effect of Selected Egyptian Cultivars of Flaxseed Oil on a Rodent Model of Postpartum Depression. ( 29333185 )
2017
41
Maternal touch in caregiving behavior of mothers with and without postpartum depression. ( 28946023 )
2017
42
Psychoeducational preventive treatment for women at risk of postpartum depression: study protocol for a randomized controlled trial, PROGEA. ( 28086766 )
2017
43
Genetic variants of the kynurenine-3-monooxygenase and postpartum depressive symptoms after cesarean section in Chinese women. ( 28319697 )
2017
44
Social Support and Postpartum Depression Revisited: The Traditional Female Role as Moderator among Mexican Women. ( 28936028 )
2017
45
Refugee and Immigrant Women's Experience of Postpartum Depression: A Meta-Synthesis. ( 28826328 )
2017
46
Predictors of Postpartum Depression in Dubai, a Rapidly Growing Multicultural Society in the United Arab Emirates. ( 28953784 )
2017
47
A closer look at the preventative effect of antidepressants in postpartum depression. ( 28050649 )
2017
48
A neuro-immune, neuro-oxidative and neuro-nitrosative model of prenatal and postpartum depression. ( 28941769 )
2017
49
Insomnia, postpartum depression and estradiol in women after delivery. ( 28791548 )
2017
50
The perception of fairness in infant care and mothers' postpartum depression. ( 28866473 )
2017
Sources

Variations for Postpartum Depression

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Sources

Expression for Postpartum Depression

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Search GEO for disease gene expression data for Postpartum Depression.
Sources

Pathways for Postpartum Depression

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Pathways related to Postpartum Depression according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
cAMP signaling pathway 37
Show member pathways
 11.96 BDNF HTR1A OXTR
2
Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways 1
11.67 BDNF HTR1A MAOA SLC6A4
3
Serotonergic synapse 37
11.6 HTR1A MAOA SLC6A4
4
Tyrosine metabolism 37
Show member pathways
 11.31 COMT MAOA TPO
5
Prostaglandin Synthesis and Regulation 1
10.93 HSD11B1 PRL
6
Biogenic Amine Synthesis 1
Show member pathways
 10.78 COMT MAOA
7
noradrenaline and adrenaline degradation 1
Show member pathways
 10.58 COMT MAOA
8
Selective Serotonin Reuptake Inhibitor Pathway, Pharmacodynamics 61
10.58 HTR1A MAOA SLC6A4
9
Dopamine metabolism 1
10.47 COMT MAOA
10
Neurotransmitter Clearance In The Synaptic Cleft 66
Show member pathways
 10.21 COMT MAOA SLC6A4
Sources

GO Terms for Postpartum Depression

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Biological processes related to Postpartum Depression according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 response to drug GO:0042493 9.78 COMT CRH OXTR SLC6A4
2 response to estradiol GO:0032355 9.67 ESR1 OXTR SLC6A4
3 response to cocaine GO:0042220 9.54 CRH OXTR
4 response to pain GO:0048265 9.52 COMT CRH
5 vasoconstriction GO:0042310 9.51 HTR1A SLC6A4
6 memory GO:0007613 9.5 BDNF OXTR SLC6A4
7 neurotransmitter catabolic process GO:0042135 9.46 COMT MAOA
8 catecholamine metabolic process GO:0006584 9.43 COMT MAOA
9 response to estrogen GO:0043627 9.43 COMT CRH ESR1
10 glucocorticoid biosynthetic process GO:0006704 9.4 CRH HSD11B1
11 dopamine catabolic process GO:0042420 9.37 COMT MAOA
12 sperm ejaculation GO:0042713 9.16 OXTR SLC6A4
13 regulation of serotonin secretion GO:0014062 8.96 CRH HTR1A
14 female pregnancy GO:0007565 8.92 COMT CRH OXTR PRL

Molecular functions related to Postpartum Depression according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 steroid binding GO:0005496 8.62 ESR1 HSD11B1
Sources

Sources for Postpartum Depression

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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