MCID: PST103
MIFTS: 31

Postpartum Psychosis

Categories: Reproductive diseases, Rare diseases

Aliases & Classifications for Postpartum Psychosis

MalaCards integrated aliases for Postpartum Psychosis:

Name: Postpartum Psychosis 59 73
Puerperal Psychosis 59

Characteristics:

Orphanet epidemiological data:

59
postpartum psychosis
Inheritance: Not applicable;

Classifications:



External Ids:

Orphanet 59 ORPHA443173
ICD10 via Orphanet 34 F53.1
UMLS via Orphanet 74 C0520678
UMLS 73 C0520678

Summaries for Postpartum Psychosis

MalaCards based summary : Postpartum Psychosis, also known as puerperal psychosis, is related to urea cycle disorder and bipolar disorder. An important gene associated with Postpartum Psychosis is MIR146A (MicroRNA 146a), and among its related pathways/superpathways are Carbon metabolism and Amino Acid metabolism. The drugs Goserelin and Hormone Antagonists have been mentioned in the context of this disorder. Affiliated tissues include brain and monocytes.

Wikipedia : 76 Postpartum psychosis is a rare psychiatric emergency in which symptoms of high mood and racing thoughts... more...

Related Diseases for Postpartum Psychosis

Graphical network of the top 20 diseases related to Postpartum Psychosis:



Diseases related to Postpartum Psychosis

Symptoms & Phenotypes for Postpartum Psychosis

Drugs & Therapeutics for Postpartum Psychosis

Drugs for Postpartum Psychosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Goserelin Approved Not Applicable 65807-02-5 47725 5311128
2 Hormone Antagonists Not Applicable
3 Hormones Not Applicable
4 Hormones, Hormone Substitutes, and Hormone Antagonists Not Applicable
5 Antineoplastic Agents, Hormonal Not Applicable
6
Serotonin Investigational, Nutraceutical Not Applicable 50-67-9 5202

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Impact of Family Psychoeducation on Psychosis Unknown status NCT01172106 Not Applicable
2 Risk Factors for Postpartum Psychosis Completed NCT00872313
3 Paternal Psychosis After Baby Born Completed NCT01011088
4 Neuropsychobiological Correlates of Sex-steroid Hormone Manipulation in Healthy Women: a Risk Model for Depression Completed NCT02661789 Not Applicable Goserelin 3.6 mg implant;Placebo
5 National Prospective and Comparative Study on the Mode of Delivery of Twins Completed NCT01987063

Search NIH Clinical Center for Postpartum Psychosis

Genetic Tests for Postpartum Psychosis

Anatomical Context for Postpartum Psychosis

MalaCards organs/tissues related to Postpartum Psychosis:

41
Brain, Monocytes

Publications for Postpartum Psychosis

Articles related to Postpartum Psychosis:

(show top 50) (show all 52)
# Title Authors Year
1
Qualitative exploration of the effect of a television soap opera storyline on women with experience of postpartum psychosis. ( 29971150 )
2018
2
Anti-NMDA receptor encephalitis presenting as postpartum psychosis-a clinical description and review. ( 29417305 )
2018
3
Are infectious agents involved in the pathogenesis of postpartum psychosis? ( 29310062 )
2018
4
Non-reproductive triggers of postpartum psychosis. ( 27722949 )
2017
5
Estrogen pathway related genes and their association with risk of postpartum psychosis: A case control study. ( 28483099 )
2017
6
Safe Use of Atypical Antipsychotics in a Patient With Postpartum Psychosis and a History of Seronegative Myasthenia Gravis. ( 28703945 )
2017
7
The global prevalence of postpartum psychosis: a systematic review. ( 28754094 )
2017
8
Catatonia among women with postpartum psychosis in a Mother-Baby inpatient psychiatry unit. ( 28274337 )
2017
9
Understanding the pathophysiology of postpartum psychosis: Challenges and new approaches. ( 28713685 )
2017
10
Phenotypical characteristics of postpartum psychosis: A clinical cohort study. ( 28699248 )
2017
11
A qualitative investigation in the role of the baby in recovery from postpartum psychosis. ( 28138996 )
2017
12
Risk of postpartum psychosis after IVF treatment: a nationwide case-control study. ( 27927846 )
2017
13
Suicide and filicide in postpartum psychosis. ( 27778148 )
2017
14
Mania triggered by sleep loss and risk of postpartum psychosis in women with bipolar disorder. ( 28889048 )
2017
15
Some unusual forms of early onset postpartum psychosis. ( 27744500 )
2017
16
Immune system aberrations in postpartum psychosis: An immunophenotyping study from a tertiary care neuropsychiatric hospital in India. ( 28778450 )
2017
17
Brain structure in women at risk of postpartum psychosis: an MRI study. ( 29249808 )
2017
18
Letter to the Editor: Postpartum psychosis and pre-eclamptic toxaemia: a reply. ( 27293149 )
2016
19
The birth of a psychiatric orphan disorder: postpartum psychosis. ( 27262047 )
2016
20
Is sleep disruption a trigger for postpartum psychosis? ( 27143002 )
2016
21
Letter to the Editor: Postpartum psychosis and pre-eclamptic toxaemia. ( 27279349 )
2016
22
Tryptophan pathway alterations in the postpartum period and in acute postpartum psychosis and depression. ( 26454336 )
2016
23
Men's experiences of having a partner who requires Mother and Baby Unit admission for first episode postpartum psychosis. ( 27533096 )
2016
24
Examination of a four-step treatment algorithm for postpartum psychosis. ( 26701386 )
2016
25
A pharmacological mouse model suggests a novel risk pathway for postpartum psychosis. ( 27728876 )
2016
26
Risk of Postpartum Relapse in Bipolar Disorder and Postpartum Psychosis: A Systematic Review and Meta-Analysis. ( 26514657 )
2016
27
Postpartum Psychosis: Madness, Mania, and Melancholia in Motherhood. ( 27609245 )
2016
28
Functional Recovery After Postpartum Psychosis: A Prospective Longitudinal Study. ( 27631144 )
2016
29
Pharmacological lactation suppression with D2 receptor agonists and risk of postpartum psychosis: A systematic review. ( 27297803 )
2016
30
Adverse childhood life events and postpartum psychosis in bipolar disorder. ( 27420133 )
2016
31
Smoking and postpartum psychosis. ( 26241192 )
2015
32
Autoimmune Encephalitis in Postpartum Psychosis. ( 26183699 )
2015
33
One Brain, Two Specialties, Converging Mechanisms: Neuronal Autoantibodies as a Rare Cause of Postpartum Psychosis. ( 26324300 )
2015
34
Postpartum psychosis: a valuable misnomer. ( 25526941 )
2015
35
Obstetric Characteristics and Management of Patients with Postpartum Psychosis in a Tertiary Hospital Setting. ( 26089908 )
2015
36
What is in a name? Causative explanatory models of postpartum psychosis among patients and caregivers in India. ( 26238989 )
2015
37
Understanding postpartum psychosis. ( 26364332 )
2015
38
Quetiapine in postpartum psychosis. ( 24943395 )
2014
39
The Recovery Process of Postpartum Psychosis from Both the Woman's and Next of Kin's Perspective - An Interview Study in Sweden. ( 24660040 )
2014
40
A narratology of postpartum psychosis in an Orthodox Jewish woman. ( 25040213 )
2014
41
Postpartum psychosis in a woman with Graves' disease: a case report. ( 25194170 )
2014
42
Postpartum psychosis: risk factors identification. ( 25006563 )
2014
43
Postpartum psychosis: what is in a name? ( 25410627 )
2014
44
A case of NMDAR encephalitis misdiagnosed as postpartum psychosis and neuroleptic malignant syndrome. ( 25267686 )
2014
45
Reproductive outcomes and risk of subsequent illness in women diagnosed with postpartum psychosis. ( 23651079 )
2013
46
Involving the family in the care and treatment of women with postpartum psychosis: Swedish psychiatrists' experiences. ( 24236289 )
2013
47
Down-regulation of inflammation-protective microRNAs 146a and 212 in monocytes of patients with postpartum psychosis. ( 23295264 )
2013
48
Misdiagnosed postpartum psychosis revealing a late-onset urea cycle disorder. ( 21642480 )
2011
49
First manifestation of citrullinemia type I as differential diagnosis to postpartum psychosis in the puerperal period. ( 20005624 )
2010
50
Differentiation and clinical implications of postpartum depression and postpartum psychosis. ( 19538615 )
2009

Variations for Postpartum Psychosis

Expression for Postpartum Psychosis

Search GEO for disease gene expression data for Postpartum Psychosis.

Pathways for Postpartum Psychosis

Pathways related to Postpartum Psychosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.58 ASS1 OTC
2 11.11 ASS1 OTC
3
Show member pathways
10.37 ASS1 OTC
4
Show member pathways
10 ASS1 OTC

GO Terms for Postpartum Psychosis

Biological processes related to Postpartum Psychosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to drug GO:0042493 9.46 ASS1 OTC
2 gene silencing by miRNA GO:0035195 9.43 MIR146A MIR212
3 negative regulation of angiogenesis GO:0016525 9.4 MIR146A MIR212
4 liver development GO:0001889 9.37 ASS1 OTC
5 cellular amino acid biosynthetic process GO:0008652 9.32 ASS1 OTC
6 response to zinc ion GO:0010043 9.26 ASS1 OTC
7 urea cycle GO:0000050 9.16 ASS1 OTC
8 midgut development GO:0007494 8.96 ASS1 OTC
9 arginine biosynthetic process GO:0006526 8.62 ASS1 OTC

Molecular functions related to Postpartum Psychosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mRNA binding involved in posttranscriptional gene silencing GO:1903231 8.96 MIR146A MIR212
2 amino acid binding GO:0016597 8.62 ASS1 OTC

Sources for Postpartum Psychosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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