Aliases & Classifications for Pouchitis

MalaCards integrated aliases for Pouchitis:

Name: Pouchitis 60 56 17 74

Characteristics:

Orphanet epidemiological data:

60
pouchitis
Prevalence: 1-5/10000 (Europe);

Classifications:



External Ids:

MESH via Orphanet 46 D019449
UMLS via Orphanet 75 C0376620
Orphanet 60 ORPHA217067
UMLS 74 C0376620

Summaries for Pouchitis

MalaCards based summary : Pouchitis is related to ileitis and colitis. An important gene associated with Pouchitis is NOD2 (Nucleotide Binding Oligomerization Domain Containing 2), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Ciprofloxacin and Vedolizumab have been mentioned in the context of this disorder. Affiliated tissues include prostate, colon and neutrophil, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Wikipedia : 77 Pouchitis is inflammation of the ileal pouch (an artificial rectum surgically created out of ileal gut... more...

Related Diseases for Pouchitis

Diseases related to Pouchitis via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 159, show less)
# Related Disease Score Top Affiliating Genes
1 ileitis 30.8 NOD2 TLR4
2 colitis 30.4 CXCL8 IL10 NOD2 TLR4
3 ulcerative colitis 30.4 CXCL8 IL10 NOD2 TLR4
4 pyoderma gangrenosum 30.4 CXCL8 NOD2
5 pyoderma 30.4 CXCL8 NOD2
6 inflammatory bowel disease 29.7 CXCL8 IL10 NOD2 TLR4
7 arthritis 29.5 CXCL8 IL10 IL1RN NOD2
8 uveitis 29.4 IL10 NOD2
9 crohn's disease 10.4
10 familial adenomatous polyposis 10.3
11 cytomegalovirus infection 10.2
12 hypersensitivity reaction type iv disease 10.2 IL1RN NOD2
13 spondylarthropathy 10.2 NOD2 TLR4
14 inflammatory bowel disease 6 10.2 NOD2 TLR4
15 cholangitis, primary sclerosing 10.2
16 sclerosing cholangitis 10.2
17 cholangitis 10.2
18 neisseria meningitidis infection 10.2 IL1RN TLR4
19 sapho syndrome 10.1 CXCL8 NOD2
20 crohn's colitis 10.1 CXCL8 NOD2
21 adenocarcinoma 10.1
22 pediatric ulcerative colitis 10.1
23 familial mediterranean fever 10.1 IL1RN NOD2
24 necrotizing fasciitis 10.1 CXCL8 IL1RN
25 spondyloarthropathy 1 10.1 NOD2 TLR4
26 felty syndrome 10.1 CXCL8 LTF
27 giant papillary conjunctivitis 10.1 CXCL8 LTF
28 haemophilus influenzae 10.1 CXCL8 LTF
29 superficial urinary bladder cancer 10.1 CXCL8 TLR4
30 bronchopulmonary dysplasia 10.1 CXCL8 IL1RN
31 endometrial disease 10.1 CXCL8 TLR4
32 pyelitis 10.1 CXCL8 TLR4
33 periodontosis 10.1 CXCL8 TLR4
34 gastric ulcer 10.1 CXCL8 IL1RN
35 spondylitis 10.1 IL1RN NOD2
36 bacteriuria 10.1 CXCL8 TLR4
37 septic arthritis 10.1 CXCL8 TLR4
38 oral candidiasis 10.1 CXCL8 LTF
39 middle ear disease 10.1 CXCL8 TLR4
40 silicosis 10.1 CXCL8 IL1RN
41 perinatal necrotizing enterocolitis 10.1 CXCL8 TLR4
42 invasive aspergillosis 10.0 CXCL8 TLR4
43 atrophic gastritis 10.0 CXCL8 IL1RN
44 bacterial vaginosis 10.0 CXCL8 TLR4
45 deficiency anemia 10.0
46 irritable bowel syndrome 10.0
47 duodenal ulcer 10.0 CXCL8 IL1RN
48 bacterial pneumonia 10.0 CXCL8 TLR4
49 orofacial granulomatosis 10.0 IL10 NOD2
50 gaucher disease, type ii 10.0 IL10 IL1RN
51 leprosy 3 10.0 IL10 NOD2
52 acute graft versus host disease 10.0 IL10 NOD2
53 uveal disease 10.0 IL10 NOD2
54 extrapulmonary tuberculosis 10.0 IL10 IL1RN
55 gingivitis 10.0 CXCL8 LTF
56 aphthous stomatitis 10.0 IL10 IL1RN
57 coccidioidomycosis 10.0 IL10 TLR4
58 cystic echinococcosis 10.0 IL10 TLR4
59 echinococcosis 10.0 IL10 TLR4
60 scrub typhus 9.9 IL10 TLR4
61 aspergillosis 9.9 IL10 TLR4
62 meningitis 9.9 CXCL8 IL10
63 keratoconjunctivitis sicca 9.9 IL10 LTF
64 extrinsic cardiomyopathy 9.9 IL10 TLR4
65 paracoccidioidomycosis 9.9 IL10 TLR4
66 cystitis 9.9 CXCL8 TLR4
67 tungiasis 9.9 CXCL8 IL10
68 acute transverse myelitis 9.9 CXCL8 IL10
69 transverse myelitis 9.9 CXCL8 IL10
70 vulvovaginitis 9.9 CXCL8 IL10
71 scabies 9.9 CXCL8 IL10
72 melioidosis 9.9 IL10 TLR4
73 neurosyphilis 9.9 CXCL8 IL10
74 necatoriasis 9.9 CXCL8 IL10
75 funisitis 9.9 CXCL8 IL10
76 clonorchiasis 9.9 CXCL8 IL10
77 retinitis pigmentosa 44 9.9 CXCL8 IL10
78 radiculopathy 9.9 CXCL8 IL10
79 mycetoma 9.9 CXCL8 IL10
80 filariasis 9.9 IL10 TLR4
81 primary peritoneal carcinoma 9.9 CXCL8 IL10
82 acute pyelonephritis 9.9 CXCL8 IL10
83 familial adenomatous polyposis 1 9.9
84 prostate cancer 9.9
85 anemia, autoimmune hemolytic 9.9
86 prostate cancer, hereditary, 8 9.9
87 prostate cancer, hereditary, 6 9.9
88 hemolytic anemia 9.9
89 hepatitis 9.9
90 microscopic colitis 9.9
91 diversion colitis 9.9
92 igg4-related disease 9.9
93 spondyloarthropathy 9.9
94 iron deficiency anemia 9.9
95 iritis 9.9
96 frozen shoulder 9.9
97 hepatitis c 9.9
98 iron metabolism disease 9.9
99 bursitis 9.9
100 gastroduodenitis 9.9
101 central serous chorioretinopathy 9.9
102 depression 9.9
103 viral encephalitis 9.9 CXCL8 IL10
104 synovitis 9.9 CXCL8 IL1RN
105 prostatitis 9.9 CXCL8 IL10
106 mastitis 9.9 CXCL8 LTF NOD2
107 nose disease 9.9 CXCL8 IL10
108 leptospirosis 9.9 CXCL8 IL10
109 cutaneous leishmaniasis 9.8 IL10 TLR4
110 appendicitis 9.8 CXCL8 IL10
111 bronchiolitis obliterans 9.8 CXCL8 IL10
112 adult respiratory distress syndrome 9.8 CXCL8 IL10
113 dengue hemorrhagic fever 9.8 CXCL8 IL10
114 chorioamnionitis 9.8 CXCL8 IL1RN TLR4
115 extrinsic allergic alveolitis 9.8 CXCL8 IL10
116 periodontal disease 9.8 CXCL8 IL1RN TLR4
117 allergic contact dermatitis 9.8 CXCL8 IL10
118 contact dermatitis 9.8 CXCL8 IL10
119 pulmonary edema 9.8 CXCL8 IL10
120 bacterial meningitis 9.8 CXCL8 IL10
121 upper respiratory tract disease 9.8 CXCL8 IL10
122 gastroenteritis 9.8 CXCL8 IL10
123 toxoplasmosis 9.8 IL10 TLR4
124 endocarditis 9.8 CXCL8 IL10
125 alcoholic hepatitis 9.8 CXCL8 IL10
126 bronchial disease 9.8 CXCL8 IL10
127 q fever 9.7 IL10 NOD2 TLR4
128 idiopathic neutropenia 9.7 IL10 IL1RN TLR4
129 peritonitis 9.7 CXCL8 IL10
130 trypanosomiasis 9.7 CXCL8 IL10
131 aseptic meningitis 9.7 CXCL8 IL10 IL1RN
132 peptic ulcer disease 9.7 CXCL8 IL10 IL1RN
133 osteomyelitis 9.7 CXCL8 IL10 IL1RN
134 bone inflammation disease 9.7 CXCL8 IL10 IL1RN
135 periodontitis 9.6 CXCL8 IL10 TLR4
136 bacterial sepsis 9.6 CXCL8 IL10 TLR4
137 pyelonephritis 9.6 CXCL8 IL10 TLR4
138 shigellosis 9.6 CXCL8 IL10 LTF
139 primary bacterial infectious disease 9.6 CXCL8 IL10 TLR4
140 visceral leishmaniasis 9.6 CXCL8 IL10 TLR4
141 chlamydia 9.6 CXCL8 IL10 TLR4
142 toxic shock syndrome 9.6 CXCL8 IL10 TLR4
143 bronchiolitis 9.6 CXCL8 IL10 TLR4
144 otitis media 9.6 CXCL8 IL10 TLR4
145 mouth disease 9.6 IL10 TLR4
146 chagas disease 9.6 CXCL8 IL10 TLR4
147 respiratory system disease 9.6 CXCL8 IL10 TLR4
148 pneumonia 9.6 CXCL8 IL10 TLR4
149 omenn syndrome 9.5 IL10 IL1RN
150 lymphadenitis 9.4 CXCL8 IL10 NOD2 TLR4
151 intestinal disease 9.4 CXCL8 IL10 NOD2 TLR4
152 bacterial infectious disease 9.4 CXCL8 IL10 NOD2 TLR4
153 brucellosis 9.4 CXCL8 IL10 IL1RN TLR4
154 proteasome-associated autoinflammatory syndrome 1 9.4 CXCL8 IL10 IL1RN TLR4
155 rheumatoid arthritis 9.3 CXCL8 IL10 IL1RN TLR4
156 malaria 9.3 CXCL8 IL10 IL1RN TLR4
157 behcet syndrome 9.1 CXCL8 IL10 IL1RN NOD2 TLR4
158 gastrointestinal system disease 9.1 CXCL8 IL10 LTF NOD2 TLR4
159 aggressive periodontitis 9.1 CXCL8 IL10 IL1RN LTF TLR4

Graphical network of the top 20 diseases related to Pouchitis:



Diseases related to Pouchitis

Symptoms & Phenotypes for Pouchitis

GenomeRNAi Phenotypes related to Pouchitis according to GeneCards Suite gene sharing:

27 (showing 8, show less)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-111 9.32 NOD2
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-173 9.32 IL10
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-179 9.32 IL10
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-22 9.32 TLR4
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-34 9.32 IL10
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 9.32 IL10
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-68 9.32 IL10 NOD2 TLR4
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-77 9.32 NOD2

Drugs & Therapeutics for Pouchitis

Drugs for Pouchitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 27, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
2 Vedolizumab Approved Phase 4 943609-66-3
3 Anti-Bacterial Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
4 Gastrointestinal Agents Phase 4,Phase 3,Phase 2
5 Anti-Infective Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
6 Cytochrome P-450 Enzyme Inhibitors Phase 4
7 Cytochrome P-450 CYP1A2 Inhibitors Phase 4
8 Topoisomerase Inhibitors Phase 4
9
Adalimumab Approved Phase 3 331731-18-1 16219006
10
Ursodeoxycholic acid Approved, Investigational Phase 2, Phase 3 128-13-2 31401
11
Alicaforsen Investigational Phase 3 185229-68-9 16197724
12 Antirheumatic Agents Phase 3
13 Anti-Inflammatory Agents Phase 3
14 Immunosuppressive Agents Phase 3
15 Immunologic Factors Phase 3,Not Applicable
16 Antibiotics, Antitubercular Phase 3,Phase 1,Phase 2,Not Applicable
17 Bile Acids and Salts Phase 2, Phase 3
18 Cholagogues and Choleretics Phase 2, Phase 3
19
Clotrimazole Approved, Vet_approved Phase 1, Phase 2 23593-75-1 2812
20 Antitubercular Agents Phase 1, Phase 2,Phase 2
21
Scopolamine Approved, Investigational 51-34-3, 6533-68-2 5184
22
Certolizumab pegol Approved 428863-50-7
23 Defensins
24 Acidophilus Not Applicable
25 Immunoglobulins Not Applicable
26 Antibodies Not Applicable
27 Butylscopolammonium Bromide

Interventional clinical trials:

(showing 32, show less)
# Name Status NCT ID Phase Drugs
1 VSL#3 Treatment in Children With Crohn's Disease Unknown status NCT00367705 Phase 4
2 Phase 4 Study to Evaluate the Efficacy and Safety of Vedolizumab in the Treatment of Chronic Pouchitis Recruiting NCT02790138 Phase 4 Vedolizumab;Ciprofloxacin;Vedolizumab Placebo
3 Adalimumab in the Treatment of Chronic Pouchitis Completed NCT01670240 Phase 3 Adalimumab;Placebo
4 Efficacy of Alicaforsen in Pouchitis Patients Who Have Failed to Respond to at Least One Course of Antibiotics Completed NCT02525523 Phase 3 Alicaforsen;Placebo
5 Clinical Approaches to Ileal Pouch Dysfunction Completed NCT00293553 Phase 3
6 the Prophylaxis of Recurrent Pouchitis After Fecal Microbiota Transplant in UC With Ileo-anal Anastomosis Recruiting NCT03524352 Phase 3
7 The Role of Secondary Bile Acids in Intestinal Inflammation Not yet recruiting NCT03724175 Phase 2, Phase 3 ursodiol (ursodeoxycholic acid, UDCA)
8 To Determine the Effect of Honey Enema in the Treatment of Patients With Acute Pouchitis Completed NCT02201186 Phase 2
9 FMT in Ulcerative Colitis-Associated Pouchitis Completed NCT02049502 Phase 2
10 Safety and Efficacy of AST-120 in the Treatment of Pouchitis Completed NCT00583076 Phase 2 AST-120
11 Fecal Microbiota Transplantation for Pouchitis Recruiting NCT03545386 Phase 2
12 Fecal Microbiota Transplantation in the Treatment of Pouchitis Active, not recruiting NCT03378921 Phase 2
13 Clotrimazole Enemas for Pouchitis in Children and Adults Suspended NCT00061282 Phase 1, Phase 2 Clotrimazole
14 Safety and Efficacy of Fecal Microbiome Transplantation (FMT) in the Treatment of Antibiotic Dependent Pouchitis (ADP) Terminated NCT02782325 Phase 1, Phase 2
15 Safety and Efficacy of AST-120 in the Treatment of Antibiotic-Refractory Pouchitis Terminated NCT00583531 Phase 2 AST-120
16 Study of Sc-FOS for Pouchitis Prevention Active, not recruiting NCT02203955 Phase 1 Short-Chain Fructooligosaccharide;Maltodextrin
17 The Interaction Between Intestinal Microbiota, Innate Defense and Epithelial Integrity in the Development of Pouchitis Unknown status NCT01202396
18 Microbiota and Immune microEnvironment in Pouchitis Unknown status NCT03136419 Not Applicable
19 Clinical Outcome After Close Rectal Ileo Pouch Anal Anastomosis for Colitis Ulcerosa(CU) Unknown status NCT01111708 Not Applicable
20 The Effect of Diet on Microbial Profile and Disease Outcomes in Patients With Inflammatory Bowel Diseases Unknown status NCT02858557 Not Applicable
21 Fecal Microbiota Transplant (FMT) for Pouchitis Completed NCT02428361 Early Phase 1 Biologically active human fecal material, OpenBiome
22 Fecal Transplantation for Chronic Pouchitis - A Pilot Study Completed NCT03538366 Not Applicable
23 Nutritional Impact of Serum-Derived Bovine Immunoglobulin Protein Isolate in Subjects With IPAA Completed NCT02828410 Not Applicable
24 Surgical Reconstruction in Ulcerative Colitis With Primary Sclerosing Cholangitis Completed NCT01798953
25 Complications and Outcomes of Pouch Excision Completed NCT03952195
26 Characterization of Disease Related Changes in Inflammatory Bowel Disease Using Fecal Metabolite Profiling Completed NCT01666717
27 MRI in Normal Ileal Pouches, and a Feasibility Study of Dynamic MRI Enema and Defaecating MRI Pouchography Recruiting NCT02925260
28 TAMIS-IPAA vs. Lap-IPAA for Ulcerative Colitiis Recruiting NCT03536988 Not Applicable
29 Corrona Inflammatory Bowel Disease (IBD) Registry Enrolling by invitation NCT03162549
30 Hyperbaric Oxygen Therapy for Antibiotic Refractory Pouchitis Not yet recruiting NCT03526796 Not Applicable
31 EUS Evaluation of Perianal and Peri-rectal Fistulizing Crohn's Disease With CERTOLIZUMAB Treatment Terminated NCT01582568 Certolizumab
32 Ileal Pouch-Anal Anastomosis Registry Terminated NCT01026480

Search NIH Clinical Center for Pouchitis

Genetic Tests for Pouchitis

Anatomical Context for Pouchitis

MalaCards organs/tissues related to Pouchitis:

42
Prostate, Colon, Neutrophil, Small Intestine, Testes, Monocytes, Bone

Publications for Pouchitis

Articles related to Pouchitis:

(showing 451, show less)
# Title Authors Year
1
Difference in the frequency of pouchitis between ulcerative colitis and familial adenomatous polyposis: is the explanation in peripouch fat? ( 30985958 )
2019
2
Predictors for Pouchitis After Ileal Pouch-Anal Anastomosis for Pediatric-Onset Ulcerative Colitis. ( 30743232 )
2019
3
Response to the Letter to the Editor from Dai et al, Regarding "Smoking and the Risk of Pouchitis in Ulcerative Colitis Patients with Ileal Pouch Anal Anastomosis". ( 30124832 )
2019
4
The Effect of Smoking on the Risk of Pouchitis in Ulcerative Colitis Patients With Ileal Pouch-anal Anastomosis. ( 30124837 )
2019
5
How do you treat this diversion ileitis and pouchitis? ( 29588334 )
2019
6
Pouchitis as an Indication for Ileal Pouch Surgical Revision. ( 29939252 )
2019
7
The therapy of chronic pouchitis. ( 30623632 )
2019
8
Adalimumab in the treatment of chronic pouchitis. A randomized double-blind, placebo-controlled trial. ( 30739519 )
2019
9
Efficacy of Vedolizumab for Refractory Pouchitis of the Ileo-anal Pouch: Results From a Multicenter US Cohort. ( 30810748 )
2019
10
Fruit consumption is associated with alterations in microbial composition and lower rates of pouchitis. ( 30828722 )
2019
11
Vedolizumab for chronic antibiotic-refractory pouchitis. ( 30976425 )
2019
12
The efficacy of fecal microbiota transplantation for patients with chronic pouchitis: A case series. ( 30997086 )
2019
13
Fecal Proteases from Pouchitis Patients Activate Protease Activating Receptor-2 to Disrupt the Epithelial Barrier. ( 31056700 )
2019
14
Successful treatment with tacrolimus of refractory pyoderma gangrenosum with pouchitis after restorative proctocolectomy for ulcerative colitis. ( 30618342 )
2018
15
Early first episode of pouchitis after ileal pouch-anal anastomosis for pediatric ulcerative colitis is a risk factor for development of chronic pouchitis. ( 30446392 )
2018
16
Smoking and the Risk of Pouchitis in Ulcerative Colitis Patients With Ileal Pouch-Anal Anastomosis. ( 29788269 )
2018
17
Diversion colitis and pouchitis: A mini-review. ( 29713128 )
2018
18
Festschrift for Ronan O'Connell: pouchitis, ulcerative colitis and the microbiome. ( 29524104 )
2018
19
Systematic Review With Meta-Analysis: Anti-TNF Therapy in Refractory Pouchitis and Crohn's Disease-Like Complications of the Pouch After Ileal Pouch-Anal Anastomosis Following Colectomy for Ulcerative Colitis. ( 29361101 )
2018
20
Colonic Histological Criteria Predict Development of Pouchitis after Ileal Pouch: Anal Anastomosis for Patients with Ulcerative Colitis. ( 28662525 )
2018
21
Refractory Chronic Pouchitis and Autoimmune Hemolytic Anemia Successfully Treated with Vedolizumab. ( 30480056 )
2018
22
Effective use of ustekinumab for prepouch ileitis without improvement of concomitant pouchitis. ( 29423578 )
2018
23
Refractory pouchitis improves after administration of the green tea polyphenol EGCG: a retrospective review. ( 28929216 )
2018
24
Vedolizumab in the treatment of chronic, antibiotic-dependent or refractory pouchitis. ( 29266360 )
2018
25
Editorial: biologic therapy for chronic pouchitis - are we beginning to meet the unmet need? ( 29446134 )
2018
26
Another RESIN for Pouchitis: Chronic Pouchitis With Erosion Secondary to Sodium Polystyrene Sulfonate Crystals. ( 29535436 )
2018
27
Long-term follow-up of the use of maintenance antibiotic therapy for chronic antibiotic-dependent pouchitis. ( 29588846 )
2018
28
Ustekinumab Rescue Therapy in a Patient With Chronic Refractory Pouchitis. ( 29659775 )
2018
29
Reliability among central readers in the evaluation of endoscopic disease activity in pouchitis. ( 29660321 )
2018
30
Management of Pouchitis and Other Common Complications of the Pouch. ( 29688472 )
2018
31
Use of vedolizumab in a patient with chronic and refractory pouchitis. ( 29720865 )
2018
32
Placebo Rates in Randomized Controlled Trials of Pouchitis Therapy. ( 29995184 )
2018
33
Identifying Outcomes in Clinical Trials of Pouchitis for the Development of a Core Outcome Set. ( 30268563 )
2018
34
Central Serous Chorioretinopathy in a Patient with Ulcerative Colitis with Pouchitis on Budesonide-EC. ( 28328626 )
2017
35
Successful Treatment With Vedolizumab in a Patient With Chronic Refractory Pouchitis and Primary Sclerosing Cholangitis. ( 29106505 )
2017
36
NOD2 Genetic Variants Predispose One of Two Familial Adenomatous Polyposis Siblings to Pouchitis Through Microbiome Dysbiosis. ( 28633443 )
2017
37
Endoscopic Treatment of Bleeding Diversion Pouchitis with High-Concentration Dextrose Spray. ( 28377939 )
2017
38
Intestinal Barrier Disruption in Ileal Pouchitis After Ileal Pouch-Anal Anastomosis in a Rat Model. ( 28486255 )
2017
39
Predictors of pouchitis after ileal pouch-anal anastomosis in pediatric-onset ulcerative colitis. ( 28542114 )
2017
40
Altered expression of microRNAs in patients with pouchitis after restorative proctocolectomy. ( 28600635 )
2017
41
Successful treatment of chronic refractory pouchitis with vedolizumab. ( 28698974 )
2017
42
Lactobacillus acidophilus alleviates pouchitis after ileal pouch-anal anastomosis in rats. ( 28765694 )
2017
43
Alicaforsen in the treatment of pouchitis. ( 29067882 )
2017
44
Abdominal Visceral Fat Area and Chronic Pouchitis after Ileal Pouch-Anal Anastomosis. ( 29391089 )
2017
45
Hyperbaric oxygen therapy for chronic antibiotic-refractory ischemic pouchitis. ( 26319238 )
2017
46
Specific members of the predominant gut microbiota predict pouchitis following colectomy and IPAA in UC. ( 26423113 )
2017
47
Alterations of Enteric Microbiota in Patients with a Normal Ileal Pouch Are Predictive of Pouchitis. ( 27613294 )
2017
48
Pouchitis after ileal pouch-anal anastomosis in ulcerative colitis: Diagnosis, management, risk factors, and incidence. ( 27681447 )
2017
49
The prevalence of chronic peri-pouch sepsis in patients treated for antibiotic-dependent or refractory primary idiopathic pouchitis. ( 27688067 )
2017
50
Efficacy of Vedolizumab in Patients with Antibiotic and Anti-tumor Necrosis Alpha Refractory Pouchitis. ( 27930413 )
2017
51
Tripterygium wilfordii polyglycosidium ameliorates pouchitis induced by dextran sulfate sodium in rats. ( 27988458 )
2017
52
Systematic review with meta-analysis: the management of chronic refractory pouchitis with an evidence-based treatment algorithm. ( 28008631 )
2017
53
Successful treatment of pouchitis with Vedolizumab, but not fecal microbiota transfer (FMT), after proctocolectomy in ulcerative colitis. ( 28097380 )
2017
54
Sulfasalazine in Prevention of Pouchitis After Proctocolectomy with Ileal Pouch-Anal Anastomosis for Ulcerative Colitis. ( 28110377 )
2017
55
Successful Treatment With Ustekinumab for Chronic Refractory Pouchitis. ( 28199485 )
2017
56
Efficacy of granulocyte and monocyte apheresis for antibiotic-refractory pouchitis after proctocolectomy for ulcerative colitis: an open-label, prospective, multicentre study. ( 28203278 )
2017
57
Early Transcriptomic Changes in the Ileal Pouch Provide Insight into the Molecular Pathogenesis of Pouchitis and Ulcerative Colitis. ( 28221248 )
2017
58
Cryptosporidium Pouchitis. ( 28223201 )
2017
59
Combination therapy with vedolizumab and etanercept in a patient with pouchitis and spondylarthritis. ( 28243458 )
2017
60
Frequency and Risk Factors of Clostridium difficile Infection in Hospitalized Patients With Pouchitis: A Population-based Study. ( 28296825 )
2017
61
Preoperative Extraintestinal Manifestations Associated with Chronic Pouchitis in Japanese Patients with Ulcerative Colitis After Ileal Pouch-anal Anastomosis: A Retrospective Study. ( 28346273 )
2017
62
Campylobacter Pouchitis Mimicking the Appearance of Crohn's Disease. ( 27555972 )
2016
63
Pouchitis Is a Common Complication in Patients With Familial Adenomatous Polyposis Following Ileal Pouch-Anal Anastomosis. ( 27085760 )
2016
64
Immunoglobulin G4 (IgG4)-associated pouchitis - Part of IgG4 related disease? A case series and review of the literature. ( 27038705 )
2016
65
Incidence and Severity of Prepouch Ileitis: A Distinct Disease Entity or a Manifestation of Refractory Pouchitis? ( 26383915 )
2016
66
Pouchitis in Pediatric Ulcerative Colitis Patients After Ileal Pouch Anal Anastomosis. ( 27602702 )
2016
67
Male Gender Is Associated with a High Risk for Chronic Antibiotic-Refractory Pouchitis and Ileal Pouch Anastomotic Sinus. ( 26446071 )
2016
68
Ursodeoxycholic Acid Inhibits Clostridium difficile Spore Germination and Vegetative Growth, and Prevents the Recurrence of Ileal Pouchitis Associated With the Infection. ( 26485102 )
2016
69
The effect of Clostridium butyricum MIYAIRI on the prevention of pouchitis and alteration of the microbiota profile in patients with ulcerative colitis. ( 26510664 )
2016
70
Successful treatment of chronic Pouchitis utilizing fecal microbiota transplantation (FMT): a case report. ( 26525055 )
2016
71
Short article: Successful faecal coliform sensitivity-based oral ertapenem therapy for chronic antibiotic-refractory pouchitis: a case series. ( 26657456 )
2016
72
Endoluminal calprotectin measurement in assessment of pouchitis and a new index of disease activity: a pilot study. ( 26901424 )
2016
73
Alicaforsen, an antisense inhibitor of ICAM-1, as treatment for chronic refractory pouchitis after proctocolectomy: A case series. ( 26966529 )
2016
74
Fecal Microbiota Transfer in Patients With Chronic Antibiotic-Refractory Pouchitis. ( 27018122 )
2016
75
The current place of probiotics and prebiotics in the treatment of pouchitis. ( 27048898 )
2016
76
Secondary pouchitis in a pediatric patient successfully treated by salvage surgery. ( 27097567 )
2016
77
Predictors of Pouchitis After Ileal Pouch-Anal Anastomosis in Children. ( 27243421 )
2016
78
Review article: the pathogenesis of pouchitis. ( 27554912 )
2016
79
Role of intestinal flora imbalance in pathogenesis of pouchitis. ( 27569889 )
2016
80
Predictors of Pouchitis After Ileal Pouch-Anal Anastomosis in Children. ( 27574882 )
2016
81
Pouchitis Associated With Pelvic Radiation for Prostate Cancer. ( 27807581 )
2016
82
Fecal microbiota in pouchitis and ulcerative colitis. ( 27833384 )
2016
83
Patient-Specific Bacteroides Genome Variants in Pouchitis. ( 27935837 )
2016
84
Methodological Quality Assessment of Meta-Analyses and Systematic Reviews of Probiotics in Inflammatory Bowel Disease and Pouchitis. ( 28005973 )
2016
85
Faecal matrix metalloprotease-9 is a more sensitive marker for diagnosing pouchitis than faecal calprotectin: results from a pilot study. ( 25264031 )
2015
86
Quality of life, continence and frequency of pouchitis following laparoscopic versus open colectomy and ileal pouch-anal anastomosis: an Irish perspective. ( 25422064 )
2015
87
Autoimmune features are associated with chronic antibiotic-refractory pouchitis. ( 25437817 )
2015
88
FK506-Binding Protein 5 mRNA Levels in Ileal Mucosa Are Associated with Pouchitis in Patients with Ulcerative Colitis. ( 25596721 )
2015
89
Serum alpha-1 antitrypsin: a noninvasive marker of pouchitis. ( 25659085 )
2015
90
Consecutive Monitoring of Fecal Calprotectin and Lactoferrin for the Early Diagnosis and Prediction of Pouchitis after Restorative Proctocolectomy for Ulcerative Colitis. ( 25916224 )
2015
91
Serial Fecal Calprotectin and Lactoferrin Measurements for Early Diagnosis of Pouchitis After Proctocolectomy for Ulcerative Colitis: Is Pouchoscopy No Longer Needed? ( 26052770 )
2015
92
Use of Biologics in Pouchitis: A Systematic Review. ( 26084005 )
2015
93
The therapeutic potential of antibiotics and probiotics in the treatment of pouchitis. ( 26202437 )
2015
94
Variable alterations of the microbiota, without metabolic or immunological change, following faecal microbiota transplantation in patients with chronic pouchitis. ( 26264409 )
2015
95
Inflammatory pouch disease: The spectrum of pouchitis. ( 26269664 )
2015
96
Clinical Features of Refractory Pouchitis with Penetrating Lesions and the Efficacy of Infliximab Treatment for Patients with Ulcerative Colitis after Restorative Proctocolectomy. ( 26343749 )
2015
97
Role of Probiotics in Crohn's Disease and in Pouchitis. ( 26447964 )
2015
98
Treatment and prevention of pouchitis after ileal pouch-anal anastomosis for chronic ulcerative colitis. ( 26593456 )
2015
99
Frequency, Clinical Features and Factors Associated with Pouchitis after Proctocolectomy with Ileo-Pouch-Anal Anastomosis in Patients with Ulcerative Colitis: A Latin-American Country Retrospective-Cohort Study. ( 26609703 )
2015
100
Protracted primary cytomegalovirus infection presenting as ileoanal pouchitis in a non-immunosuppressed patient: a case report. ( 24885004 )
2014
101
Fecal transplantation therapy for Clostridium difficile-associated pouchitis. ( 24132529 )
2014
102
Chronic pouchitis is associated with pouch polyp formation in patients with underlying ulcerative colitis. ( 24169020 )
2014
103
Role of probiotics in the management of pouchitis. ( 24180410 )
2014
104
Effect of probiotics on inducing remission and maintaining therapy in ulcerative colitis, Crohn's disease, and pouchitis: meta-analysis of randomized controlled trials. ( 24280877 )
2014
105
The association between autoimmunity and pouchitis. ( 24374879 )
2014
106
Oral beclomethasone dipropionate in chronic refractory pouchitis. ( 24394806 )
2014
107
Chronic antibiotic-refractory diversion pouchitis successfully treated with leukocyteapheresis. ( 24571541 )
2014
108
Long-term use of probiotics Lactobacillus and Bifidobacterium has a prophylactic effect on the occurrence and severity of pouchitis: a randomized prospective study. ( 24579075 )
2014
109
Treatment strategy for preventing pouchitis as a postoperative complication of ulcerative colitis: the significance of the management of cuffitis. ( 25022954 )
2014
110
Pouchitis: prevention and treatment. ( 25023187 )
2014
111
Cytomegalovirus pouchitis in a patient with Crohn's disease. ( 25035450 )
2014
112
Role of intestinal bacteria in the pathogenesis of pouchitis. ( 25046009 )
2014
113
Relationship between pouch microbiota and pouchitis following restorative proctocolectomy for ulcerative colitis. ( 25110406 )
2014
114
An uncommon complication of chronic antibiotics refractory pouchitis after ileal pouch-anal anastomosis for ulcerative colitis. ( 25158030 )
2014
115
Innate immune factors in the development and maintenance of pouchitis. ( 25222658 )
2014
116
Update on the pathogenesis and management of pouchitis. ( 25348740 )
2014
117
One year of infliximab therapy successfully improved a case of refractory pouchitis without the use of antibiotics. ( 25400178 )
2014
118
Synchronous cytomegalovirus and Clostridium difficile infection of the pouch: a trigger for chronic pouchitis? ( 26183628 )
2014
119
Alicaforsen: An Emerging Therapeutic Agent for Ulcerative Colitis and Refractory Pouchitis. ( 27785270 )
2014
120
Pouchitis associated with cytomegalovirus infection: a case study. ( 23314244 )
2013
121
Exclusive elemental diet impacts on the gastrointestinal microbiota and improves symptoms in patients with chronic pouchitis. ( 22857825 )
2013
122
Efficacy of biologic therapy in patients with chronic pouchitis. ( 22875487 )
2013
123
Elemental diet therapy for pouchitis following restorative proctocolectomy for ulcerative colitis. ( 22981615 )
2013
124
Clinical features and management of pouchitis in Japanese ulcerative colitis patients. ( 23076686 )
2013
125
Characteristics of extremely early-onset pouchitis after proctocolectomy with ileal pouch-anal anastomosis. ( 23254315 )
2013
126
Meta-analysis: serological markers and the risk of acute and chronic pouchitis. ( 23480145 )
2013
127
Long term benefit of one year infliximab administration for the treatment of chronic refractory pouchitis. ( 23523672 )
2013
128
Chronic use of PPI and H2 antagonists decreases the risk of pouchitis after IPAA for ulcerative colitis. ( 23532599 )
2013
129
Risk factors for pouchitis after surgery for ulcerative colitis. ( 23570620 )
2013
130
Pouchitis: what every gastroenterologist needs to know. ( 23602818 )
2013
131
Fecal lactoferrin: a noninvasive fecal biomarker for the diagnosis and surveillance of pouchitis. ( 23652747 )
2013
132
Oral ertapenem for refractory pouchitis. ( 23694856 )
2013
133
The natural history of anal transition zone inflammation and possible relationship to pouchitis: a long-term longitudinal study. ( 23777389 )
2013
134
Chronic pouchitis versus recurrent Crohn's disease: a diagnostic challenge. ( 23925821 )
2013
135
Predictive factors for development of chronic pouchitis after ileal pouch-anal anastomosis in ulcerative colitis. ( 23949485 )
2013
136
The effects of probiotics on barrier function and mucosal pouch microbiota during maintenance treatment for severe pouchitis in patients with ulcerative colitis. ( 23957603 )
2013
137
Topical tacrolimus therapy for antibiotic-refractory pouchitis. ( 24022534 )
2013
138
Commentary: The effects of probiotics on barrier function and mucosal pouch microbiota during maintenance treatment for severe pouchitis in patients with ulcerative colitis. ( 24206372 )
2013
139
Commentary: The effects of probiotics on barrier function and mucosal pouch microbiota during maintenance treatment for severe pouchitis in patients with ulcerative colitis - Authors' reply. ( 24206373 )
2013
140
Infliximab for the treatment of pouchitis. ( 24303499 )
2013
141
Pouchitis: a practical guide. ( 28839726 )
2013
142
Comprehensive analysis of the bacterial content of stool from patients with chronic pouchitis, normal pouches, or familial adenomatous polyposis pouches. ( 22114001 )
2012
143
The long-term clinical course of pouchitis after total proctocolectomy and IPAA for ulcerative colitis. ( 22469801 )
2012
144
Acute and chronic pouchitis--pathogenesis, diagnosis and treatment. ( 22508158 )
2012
145
Increased crypt apoptosis is a feature of autoimmune-associated chronic antibiotic refractory pouchitis. ( 22513433 )
2012
146
Discrepancy between clinical and histological effects of DHA supplementation in a rat model of pouchitis. ( 22532147 )
2012
147
Evaluation of preoperative predictors of development of pouchitis after ileal-pouch-anastomosis in ulcerative colitis. ( 22705025 )
2012
148
Bacteriology in the etiopathogenesis of pouchitis. ( 22796796 )
2012
149
Histopathological evaluation and risk factors related to the development of pouchitis in patients with ileal pouches for ulcerative colitis. ( 22892912 )
2012
150
Stricture of ileo-anal J pouch anastomosis increased the intensity of pouchitis in an experimental rat model. ( 23018348 )
2012
151
Randomized controlled trials in pouchitis. ( 23092236 )
2012
152
Trace elements and rat pouchitis. ( 23198279 )
2012
153
Pouchitis may increase the risk of dysplasia after restorative proctocolectomy in patients with ulcerative colitis. ( 21689264 )
2012
154
Efficacy of infliximab rescue therapy in patients with chronic refractory pouchitis: a multicenter study. ( 21826765 )
2012
155
Innate immune environment in ileal pouch mucosa: α5 defensin up-regulation as predictor of chronic/relapsing pouchitis. ( 21983950 )
2012
156
Etiology of pouchitis. ( 22021180 )
2012
157
Risk factors for chronic pouchitis after ileal pouch-anal anastomosis: a prospective cohort study. ( 22339717 )
2012
158
Efficacy of adalimumab rescue therapy in patients with chronic refractory pouchitis previously treated with infliximab: a case series. ( 22395225 )
2012
159
Detection of CMV in pouch mucosa in a patient with acute pouchitis: the real enemy or an innocent bystander? ( 22410348 )
2012
160
Rate and predictive factors of post-IPAA Crohn's-like disease (with or without pouchitis) in patients with ulcerative colitis. ( 23576088 )
2012
161
The role of antibiotics and probiotics in pouchitis. ( 24714229 )
2012
162
The role of probiotics in pouchitis Georgios Nalmpantidis, Theofanis Maris. ( 24714248 )
2012
163
Distinct microbiome in pouchitis compared to healthy pouches in ulcerative colitis and familial adenomatous polyposis. ( 20845425 )
2011
164
Risk of cancer in patients with chronic pouchitis after restorative proctocolectomy for ulcerative colitis. ( 19832871 )
2011
165
An open study of maintenance antibiotic therapy for chronic antibiotic-dependent pouchitis: efficacy, complications and outcome. ( 20041929 )
2011
166
IgG4-associated pouchitis. ( 20722051 )
2011
167
Surgical prophylaxis of pouchitis in ulcerative colitis. ( 21127981 )
2011
168
The diameter of the ileal J-pouch-anal anastomosis as an important risk factor of pouchitis - clinical observations. ( 21278694 )
2011
169
Perioperative factors during ileal pouch-anal anastomosis predict pouchitis. ( 21304302 )
2011
170
How to manage pouchitis in ulcerative colitis? ( 21466487 )
2011
171
TLR2 and TLR4 up-regulation and colonization of the ileal mucosa by Clostridiaceae spp. in chronic/relapsing pouchitis. ( 21601883 )
2011
172
Depression and mucosal proinflammatory cytokines are associated in patients with ulcerative colitis and pouchitis - A pilot study. ( 21683306 )
2011
173
Elevated serum IgG4 is associated with chronic antibiotic-refractory pouchitis. ( 21725838 )
2011
174
Pharmacotherapy for acute pouchitis. ( 21775695 )
2011
175
Inulin supplementation in rat model of pouchitis. ( 21887407 )
2011
176
Refractory ulcerative chronic pouchitis in a patient with Gardner syndrome following restorative proctocolectomy with ileal pouch-anal anastomosis. ( 22149567 )
2011
177
Clostridium difficile pouchitis after proctocolectomy with ileal pouch-anal anastomosis. ( 22196625 )
2011
178
One-year infliximab administration for the treatment of chronic refractory pouchitis. ( 24713783 )
2011
179
Early diagnosis of bilateral sub-deltoid bursitis using clinic-based ultrasonography in a patient receiving infliximab therapy for ulcerative pouchitis. ( 18949534 )
2010
180
Efficacy of infliximab in refractory pouchitis and Crohn's disease-related complications of the pouch: a Belgian case series. ( 19637335 )
2010
181
Complete resolution of intractable pouchitis in an obese patient following laparoscopic gastric banding. ( 19751231 )
2010
182
Secondary pouchitis: those with identifiable etiopathogenetic or triggering factors. ( 19755972 )
2010
183
Pilot study: the use of sulfasalazine for the treatment of acute pouchitis. ( 19817724 )
2010
184
Pouchitis and pouch dysfunction. ( 19944799 )
2010
185
Asymmetric endoscopic inflammation of the ileal pouch: a sign of ischemic pouchitis? ( 19998461 )
2010
186
Antibiotics and probiotics in chronic pouchitis: a comparative proteomic approach. ( 20039446 )
2010
187
In search of an effective animal model to study the nemesis of the IBD surgeon--pouchitis after IPAA. ( 20070979 )
2010
188
Pyloric gland metaplasia and pouchitis in patients with ileal pouch-anal anastomoses. ( 20121720 )
2010
189
Treatment and prevention of pouchitis after ileal pouch-anal anastomosis for chronic ulcerative colitis. ( 20556748 )
2010
190
The bacteriology of pouchitis: a molecular phylogenetic analysis using 16S rRNA gene cloning and sequencing. ( 20562611 )
2010
191
Extended spectrum beta-lactamase-producing bacteria and Clostridium difficile in patients with pouchitis. ( 20626734 )
2010
192
Diagnosis and management of pouchitis and ileoanal pouch dysfunction. ( 20890738 )
2010
193
NOD2/CARD15 mutations correlate with severe pouchitis after ileal pouch-anal anastomosis. ( 20940596 )
2010
194
Diagnosis and clinical course of ulcerative gastroduodenal lesion associated with ulcerative colitis: possible relationship with pouchitis. ( 21175478 )
2010
195
The bacterial pathogenesis and treatment of pouchitis. ( 21180613 )
2010
196
Successful long-term use of infliximab in refractory pouchitis in an adolescent. ( 21274444 )
2010
197
Partially hydrolyzed guar gum attenuates the severity of pouchitis in a rat model of ileal J pouch-anal anastomosis. ( 18594969 )
2009
198
Pouchitis, similar to active ulcerative colitis, is associated with impaired butyrate oxidation by intestinal mucosa. ( 18942762 )
2009
199
Are inflammatory bowel disease (IBD) and pouchitis a reactive enteropathy to group D streptococci (Enterococci)? ( 19097162 )
2009
200
Pathogenesis of and unifying hypothesis for idiopathic pouchitis. ( 19259080 )
2009
201
Pouchitis: an evolving clinical enigma--a review. ( 19273970 )
2009
202
Predictors of pouchitis after ileal pouch-anal anastomosis: a retrospective review. ( 19273980 )
2009
203
Galectin-3 expression in pouchitis in patients with ulcerative colitis who underwent ileal pouch-anal anastomosis (IPAA). ( 19278794 )
2009
204
Re: Adenocarcinoma arising in a background of chronic atrophic pouchitis in an ileoanal pouch for ulcerative colitis. ( 19302532 )
2009
205
Pouchitis: lessons for inflammatory bowel disease. ( 19349860 )
2009
206
Fecal coliform testing to identify effective antibiotic therapies for patients with antibiotic-resistant pouchitis. ( 19418603 )
2009
207
The efficacy and tolerability of AST-120 (spherical carbon adsorbent) in active pouchitis. ( 19436282 )
2009
208
Development of pouchitis with combination therapy with peg-interferon alpha-2b and ribavirin for chronic hepatitis C in a patient with ulcerative colitis who underwent pouch surgery. ( 19491886 )
2009
209
An assessment of bacterial dysbiosis in pouchitis using terminal restriction fragment length polymorphisms of 16S ribosomal DNA from pouch effluent microbiota. ( 19617766 )
2009
210
Fulminant Clostridium difficile-associated pouchitis with a fatal outcome. ( 19654602 )
2009
211
Clinical guidelines for the management of pouchitis. ( 19685489 )
2009
212
Pros and cons of antibiotic therapy for pouchitis. ( 19817675 )
2009
213
Pouchitis disease activity index (PDAI) does not predict patients with symptoms of pouchitis who will respond to antibiotics. ( 19882318 )
2009
214
Pouchitis and pouch dysfunction. ( 19913207 )
2009
215
Successful treatment for pouchitis with rebamipide refractory to a combination of metronidazole (MNZ) and ciprofloxacin (CFX). ( 26192795 )
2009
216
Impact of orthotopic liver transplant for primary sclerosing cholangitis on chronic antibiotic refractory pouchitis. ( 18065274 )
2008
217
Short-term treatment with infliximab in chronic refractory pouchitis and ileitis. ( 18298639 )
2008
218
On the benefit of probiotics in the management of pouchitis in patients underwent ileal pouch anal anastomosis: a meta-analysis of controlled clinical trials. ( 17940902 )
2008
219
Predictors for acute and chronic pouchitis following restorative proctocolectomy for ulcerative colitis. ( 18005192 )
2008
220
Predictors of pouchitis after ileal pouch-anal anastomosis: a retrospective review. ( 18266037 )
2008
221
Faecal calprotectin: a noninvasive diagnostic tool and marker of severity in pouchitis. ( 18301296 )
2008
222
Both preoperative perinuclear antineutrophil cytoplasmic antibody and anti-CBir1 expression in ulcerative colitis patients influence pouchitis development after ileal pouch-anal anastomosis. ( 18378498 )
2008
223
Proliferation of immature plasma cells in pouchitis mucosa in patients with ulcerative colitis. ( 18452202 )
2008
224
Chronic pouchitis is not related to small intestine bacterial overgrowth. ( 18452204 )
2008
225
Successful use of infliximab for treating fistulizing pouchitis with severe extraintestinal manifestation: a case report. ( 18452207 )
2008
226
Rifaximin for maintenance therapy in antibiotic-dependent pouchitis. ( 18573211 )
2008
227
Adenocarcinoma arising in a background of chronic atrophic pouchitis in an ileoanal pouch for ulcerative colitis. ( 18647190 )
2008
228
Leukocytapheresis for the treatment of active pouchitis: a pilot study. ( 18648745 )
2008
229
Which therapies are advisable in pouchitis? ( 18816748 )
2008
230
Pouchitis and related conditions: a new association. ( 18834418 )
2008
231
Development of pouchitis following ileal pouch-anal anastomosis (IPAA) for ulcerative colitis: A role for serological markers and microbial pattern recognition receptor genes. ( 21172204 )
2008
232
Diagnosis and treatment of pouchitis. ( 21904509 )
2008
233
Iron-deficiency anemia as presentation of pouchitis. ( 17198064 )
2007
234
Pouchitis and pre-pouch ileitis developed after restorative proctocolectomy for ulcerative colitis: a case report. ( 17278237 )
2007
235
Combined ciprofloxacin and tinidazole therapy in the treatment of chronic refractory pouchitis. ( 17279300 )
2007
236
Dysbiosis and pouchitis (Br J Surg 2006; 93: 1325-1334). ( 17315277 )
2007
237
Dysbiosis in pouchitis: evidence of unique microfloral patterns in pouch inflammation. ( 17368235 )
2007
238
Possible role of human cytomegalovirus in pouchitis after proctocolectomy with ileal pouch-anal anastomosis in patients with ulcerative colitis. ( 17373744 )
2007
239
Oral budesonide in the treatment of chronic refractory pouchitis. ( 17451569 )
2007
240
Controlled study using wireless capsule endoscopy for the evaluation of the small intestine in chronic refractory pouchitis. ( 17509099 )
2007
241
A prospective multivariate analysis of clinical factors associated with pouchitis after ileal pouch-anal anastomosis. ( 17544871 )
2007
242
Rifaximin for the treatment of active pouchitis: a randomized, double-blind, placebo-controlled pilot study. ( 17567869 )
2007
243
Portal vein thrombi after ileal pouch-anal anastomosis: its incidence and association with pouchitis. ( 17593473 )
2007
244
Irritable pouch syndrome is associated with depressiveness and can be differentiated from pouchitis by quantification of mucosal levels of proinflammatory gene transcripts. ( 17712839 )
2007
245
High-dose probiotics for the treatment of active pouchitis. ( 17934776 )
2007
246
Pouchitis atlas for objective endoscopic diagnosis. ( 17940832 )
2007
247
Pouchitis. ( 17948934 )
2007
248
Defensin expression in chronic pouchitis in patients with ulcerative colitis or familial adenomatous polyposis coli. ( 16534846 )
2006
249
Diffuse gastroduodenitis and pouchitis associated with ulcerative colitis. ( 17007066 )
2006
250
Change in the bacterial flora of pouchitis. ( 16506376 )
2006
251
Anatomic extent of colitis and disease severity are not predictors of pouchitis after restorative proctocolectomy for mucosal ulcerative colitis. ( 16528486 )
2006
252
Systematic review: the management of pouchitis. ( 16611268 )
2006
253
Chronic pouchitis after ileal pouch-anal anastomosis for ulcerative colitis: effect on quality of life. ( 16627228 )
2006
254
Postoperative joint symptoms: a risk factor for pouchitis in ulcerative colitis patients. ( 16717470 )
2006
255
Does smoking influence the risk of pouchitis following ileal pouch anal anastomosis for ulcerative colitis? ( 16803691 )
2006
256
Collagenous pouchitis. ( 16807149 )
2006
257
Pouchitis in ulcerative colitis: correlation between predictors from colectomy specimens and clinico-histological features. ( 16864967 )
2006
258
MRI of complicated pouchitis. ( 16985109 )
2006
259
Dysbiosis and pouchitis. ( 17058325 )
2006
260
Clostridium difficile-associated pouchitis. ( 17103037 )
2006
261
Arthritis accompanying ileal pouchitis or undifferentiated HLA B27-related spondyloarthropathy? ( 16079994 )
2006
262
Increased cytokine transcripts in pouchitis reflect the degree of inflammation but not the underlying entity. ( 16133004 )
2006
263
Adenocarcinoma of the ileoanal pouch for ulcerative colitis--a complication of severe chronic atrophic pouchitis? ( 16365680 )
2006
264
Bacterial and fungal microbiota in relation to probiotic therapy (VSL#3) in pouchitis. ( 16401690 )
2006
265
Successful treatment of severe pouchitis with rebamipide refractory to antibiotics and corticosteroids: a case report. ( 16489687 )
2006
266
Differentiating risk factors for acute and chronic pouchitis. ( 15645406 )
2005
267
Rifaximin-ciprofloxacin combination therapy is effective in chronic active refractory pouchitis. ( 15720360 )
2005
268
Association between fecal hydrogen sulfide production and pouchitis. ( 15747080 )
2005
269
Probiotic therapy to prevent pouchitis onset. ( 15793632 )
2005
270
Probiotic therapy in the prevention of pouchitis onset: decreased interleukin-1beta, interleukin-8, and interferon-gamma gene expression. ( 15867584 )
2005
271
Implications of pouchitis on the functional results following stapled restorative proctocolectomy. ( 15937626 )
2005
272
Inflammatory bowel disease: a new combination therapy for pouchitis. ( 15976743 )
2005
273
Mucosal blood flow in pouchitis. ( 16036537 )
2005
274
Granulocyte apheresis for pouchitis with arthritis and pyoderma gangrenosum after restorative proctocolectomy for ulcerative colitis: a case report. ( 16043996 )
2005
275
Pouchitis: a spectrum of diseases. ( 16168240 )
2005
276
Maintenance therapy with a probiotic in antibiotic-dependent pouchitis: experience in clinical practice. ( 16197493 )
2005
277
Innate immune receptor genetic polymorphisms in pouchitis: is CARD15 a susceptibility factor? ( 16239841 )
2005
278
Fecal pyruvate kinase (M2-PK): a new predictor for inflammation and severity of pouchitis. ( 16293562 )
2005
279
Secondary pouchitis in a post-operative patient with ulcerative colitis, successfully treated by salvage surgery. ( 16425404 )
2005
280
Combined carriership of TLR9-1237C and CD14-260T alleles enhances the risk of developing chronic relapsing pouchitis. ( 16437636 )
2005
281
Elevated platelet count before ileal pouch-anal anastomosis for ulcerative colitis is associated with the development of chronic pouchitis. ( 16468527 )
2005
282
Once daily high dose probiotic therapy (VSL#3) for maintaining remission in recurrent or refractory pouchitis. ( 14684584 )
2004
283
Prevention is the best defense: surgical prophylaxis of pouchitis. ( 14753221 )
2004
284
An enema formulation of alicaforsen, an antisense inhibitor of intercellular adhesion molecule-1, in the treatment of chronic, unremitting pouchitis. ( 14984374 )
2004
285
Are pANCA, ASCA, or cytokine gene polymorphisms associated with pouchitis? Long-term follow-up in 102 ulcerative colitis patients. ( 15056081 )
2004
286
Can we immunogenotypically and immunophenotypically profile patients who are at risk for pouchitis? ( 15056082 )
2004
287
Is pouchitis a clinical, endoscopic, or histologic problem? ( 15073663 )
2004
288
Delay of the first onset of pouchitis by oral intake of the probiotic strain Lactobacillus rhamnosus GG. ( 15108026 )
2004
289
Pouchitis. ( 15109376 )
2004
290
The diagnosis and treatment of pouchitis in inflammatory bowel disease. ( 15115932 )
2004
291
Incidence and therapeutic outcome of pouchitis for ulcerative colitis in Japanese patients. ( 15218235 )
2004
292
Factors associated with disease activity of pouchitis after surgery for ulcerative colitis. ( 15223678 )
2004
293
Histologic predictors of pouchitis in patients with chronic ulcerative colitis. ( 15252305 )
2004
294
Pouchitis-associated pyoderma gangrenosum following restorative proctocolectomy for ulcerative colitis. ( 15371932 )
2004
295
Diagnostic difficulties in pouchitis--experience from a single institution. ( 15469209 )
2004
296
Infliximab therapy in pediatric Crohn's pouchitis. ( 15475750 )
2004
297
Making sense of antisense: ISIS 2302 (alicaforsen) in the treatment of pouchitis. An enema formulation of alicaforsen, an antisense inhibitor of intercellular adhesion molecule-1, in the treatment of chronic, unremitting pouchits. ( 15475766 )
2004
298
Eradication of pathogenic bacteria and restoration of normal pouch flora: comparison of metronidazole and ciprofloxacin in the treatment of pouchitis. ( 15486751 )
2004
299
Management of pouch dysfunction or pouchitis with an ileoanal pouch. ( 15494291 )
2004
300
Human lymphocyte stimulation with pouchitis flora is greater than with flora from a healthy pouch but is suppressed by metronidazole. ( 15542518 )
2004
301
Clinical management of pouchitis. ( 15578518 )
2004
302
Management of refractory fistulizing pouchitis with infliximab. ( 15638238 )
2004
303
Pouchitis. ( 15703662 )
2004
304
Clostridium difficile infection--an unusual cause of refractory pouchitis: report of a case. ( 12576902 )
2003
305
Diagnosis and treatment of patients with pouchitis. ( 12600225 )
2003
306
Diagnosis and treatment of pouchitis. ( 12617884 )
2003
307
Prophylaxis of pouchitis onset with probiotic therapy: a double-blind, placebo-controlled trial. ( 12730861 )
2003
308
Prevention is the best defense: Probiotic prophylaxis of pouchitis. ( 12730892 )
2003
309
Infliximab in refractory pouchitis complicated by fistulae following ileo-anal pouch for ulcerative colitis. ( 12755839 )
2003
310
Diagnosis and management of pouchitis. ( 12761722 )
2003
311
Modified pouchitis disease activity index: a simplified approach to the diagnosis of pouchitis. ( 12794576 )
2003
312
Patients with extraintestinal manifestations have a higher risk of developing pouchitis in ulcerative colitis: multivariate analysis. ( 14621280 )
2003
313
Pouchitis prevention with probiotics. ( 14640099 )
2003
314
Treatment of pouchitis with dehydroepiandrosterone (DHEA) - a case report. ( 14648378 )
2003
315
Tropomyosin expression in the ileal pouch: a relationship with the development of pouchitis in ulcerative colitis. ( 14687823 )
2003
316
Ileal pouchitis and arthritis. ( 14723216 )
2003
317
Pouchitis in a rat model of ileal J pouch-anal anastomosis. ( 11837935 )
2002
318
Budesonide enema in pouchitis--a double-blind, double-dummy, controlled trial. ( 11856075 )
2002
319
Pouchitis: Part 1: Etiologies and risk factors. ( 11901413 )
2002
320
Four-week open-label trial of metronidazole and ciprofloxacin for the treatment of recurrent or refractory pouchitis. ( 11966499 )
2002
321
Impairment of epithelial transport but not of barrier function in idiopathic pouchitis after ulcerative colitis. ( 12010884 )
2002
322
Cancer risk assessment in long-standing pouchitis. DNA aberrations are rare in transformed neoplastic pelvic pouch mucosa. ( 12014427 )
2002
323
Review article: treatment of mild to moderate ulcerative colitis and pouchitis. ( 12047254 )
2002
324
Diagnosing pouchitis: comparative validation of two scoring systems in routine follow-up. ( 12072630 )
2002
325
Pouchitis: part 2: treatment options and their effectiveness. ( 12114933 )
2002
326
Pouchitis in Children: Therapeutic Options. ( 12207862 )
2002
327
Ileal pouchitis-related arthritis. ( 12528085 )
2002
328
Pouchitis-associated iritis (uveitis) following total proctocolectomy and ileal pouch-to-anal anastomosis in ulcerative colitis. ( 11240384 )
2001
329
Arthritis related to ileal pouchitis following total proctocolectomy for ulcerative colitis. ( 11182024 )
2001
330
Simple gas chromatography analysis of faecal butyrate: application to patients at risk of pouchitis. ( 11256793 )
2001
331
Activation of signal-transducer and activator of transcription 1 (STAT1) in pouchitis. ( 11298125 )
2001
332
Altered expression of the lymphocyte activation markers CD30 and CD27 in patients with pouchitis. ( 11305512 )
2001
333
Long-term follow-up after ileoanal pouch procedure: algorithm for diagnosis, classification, and management of pouchitis. ( 11330575 )
2001
334
Pouchitis and the risk of cancer? ( 11355320 )
2001
335
Upregulation of Fas-Fas-L (CD95/CD95L)-mediated epithelial apoptosis--a putative role in pouchitis? ( 11368534 )
2001
336
Expression of inducible and endothelial nitric oxide synthases in pouchitis. ( 11383584 )
2001
337
Pouch and pouchitis. ( 11394032 )
2001
338
Increase in cyclooxygenase-2 and nitric oxide-synthase-2 mRNAs in pouchitis without modification of inducible isoenzyme heme-oxygenase-1. ( 11467644 )
2001
339
Refractory pouchitis. ( 11475140 )
2001
340
Endoscopic and histologic evaluation together with symptom assessment are required to diagnose pouchitis. ( 11487535 )
2001
341
Risk of dysplasia in long-term ileal pouches and pouches with chronic pouchitis. ( 11487537 )
2001
342
Expression of cytokines, inducible nitric oxide synthase, and matrix metalloproteinases in pouchitis: effects of probiotic treatment. ( 11569697 )
2001
343
Association of decreased perfusion of the ileoanal pouch mucosa with early postoperative pouchitis and local septic complications. ( 11585503 )
2001
344
High level perinuclear antineutrophil cytoplasmic antibody (pANCA) in ulcerative colitis patients before colectomy predicts the development of chronic pouchitis after ileal pouch-anal anastomosis. ( 11600470 )
2001
345
The interleukin 1 receptor antagonist gene allele 2 as a predictor of pouchitis following colectomy and IPAA in ulcerative colitis. ( 11606494 )
2001
346
Allopurinol as prophylaxis against pouchitis following ileal pouch-anal anastomosis for ulcerative colitis. A randomized placebo-controlled double-blind study. ( 11686218 )
2001
347
Medical management of postoperative complications of inflammatory bowel disease: pouchitis and Crohn's disease recurrence. ( 11696286 )
2001
348
A randomized clinical trial of ciprofloxacin and metronidazole to treat acute pouchitis. ( 11720319 )
2001
349
Induction and maintenance of remission with nonpathogenic Escherichia coli in patients with pouchitis. ( 11721788 )
2001
350
Pouchitis following restorative proctocolectomy for ulcerative colitis: incidence and therapeutic outcome. ( 11768572 )
2001
351
Comparison of the Moskowitz criteria and the pouchitis disease activity index (PDAI) for diagnosis of ileoanal pouch inflammation. ( 12790982 )
2001
352
Cytomegalovirus infection as a cause of ileoanal pouchitis. ( 10813135 )
2000
353
Atypical forms of inflammatory bowel disease: microscopic colitis and pouchitis. ( 17031099 )
2000
354
Pharmacotherapy for inducing and maintaining remission in pouchitis. ( 10796613 )
2000
355
Risk factors and true incidence of pouchitis in patients after ileal pouch-anal anastomoses. ( 10833254 )
2000
356
Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: a double-blind, placebo-controlled trial. ( 10930365 )
2000
357
Probiotics in chronic pouchitis: restoring luminal microbial balance. ( 10930392 )
2000
358
Comparable expression of matrix metalloproteinases 1 and 2 in pouchitis and ulcerative colitis. ( 10940281 )
2000
359
Pouchitis is associated with mucosal imbalance between interleukin-8 and interleukin-10. ( 10961587 )
2000
360
Colectomy and ileal pouch. Transport and barrier in pouchitis. ( 11193590 )
2000
361
Misdiagnosis of specific cytomegalovirus infection of the ileoanal pouch as refractory idiopathic chronic pouchitis: report of two cases. ( 10211531 )
1999
362
Antibiotic combination therapy in patients with chronic, treatment-resistant pouchitis. ( 10383499 )
1999
363
Pattern of mucosal adaptation in acute and chronic pouchitis. ( 10528770 )
1999
364
Pouchitis: extracolonic manifestation of ulcerative colitis? ( 10788837 )
1999
365
Medical therapy for induction and maintenance of remission in pouchitis: a systematic review. ( 10028447 )
1999
366
IgG, albumin, and sCD44 in whole-gut lavage fluid are useful clinical markers for assessing the presence and activity of pouchitis. ( 10207728 )
1999
367
The use of cyclosporin retention enemas for pouchitis. ( 23577686 )
1999
368
Pouchitis associated with primary cytomegalovirus infection. ( 9468256 )
1998
369
Pouchitis: risk factors, etiology, and treatment. ( 9523515 )
1998
370
How do you treat refractory pouchitis and when do you decide to remove the pouch? ( 9589302 )
1998
371
How do you treat refractory pouchitis and when do you decide to remove the pouch? ( 9589303 )
1998
372
Preoperative terminal ileal and colonic resection histopathology predicts risk of pouchitis in patients after ileoanal pull-through procedure. ( 9605657 )
1998
373
Perinuclear anti-neutrophil cytoplasmic antibodies in ulcerative colitis after restorative proctocolectomy do not correlate with the presence of pouchitis. ( 9648991 )
1998
374
Pouchitis. ( 9705605 )
1998
375
Increased state of activation of CD4 positive T cells and elevated interferon gamma production in pouchitis. ( 9824577 )
1998
376
The implications of acute pouchitis on the long-term functional results after restorative proctocolectomy. ( 9836080 )
1998
377
Management of pouchitis. ( 9836089 )
1998
378
Pouchitis: pathophysiology and treatment. ( 9870162 )
1998
379
Smoking benefits celiac sprue and pouchitis: implications for nicotine therapy? ( 9041275 )
1997
380
Functional results after restorative proctocolectomy complicated by pouchitis. ( 9221849 )
1997
381
Long-term efficacy of bismuth carbomer enemas in patients with treatment-resistant chronic pouchitis. ( 9305474 )
1997
382
Stricture and pouchitis after ileal pouch-anal anastomosis. ( 9407824 )
1997
383
Bismuth carbomer foam enemas for active chronic pouchitis: a randomized, double-blind, placebo-controlled trial. ( 9663827 )
1997
384
Pouchitis in young patients after the ileal pouch-anal anastomosis. ( 23282802 )
1997
385
Does the surgical failure rate, increased incidence of pouchitis, and recent findings of dysplasia in pouches deter you from recommending an ileal pouch-anal anastomosis for ulcerative colitis? ( 23282811 )
1997
386
Is pouchitis a systemic manifestation of inflammatory bowel disease? ( 23282813 )
1997
387
Pouchitis risk: flip the coin? ( 23282881 )
1997
388
Sulindac-associated ulcerative pouchitis in familial adenomatous polyposis. ( 8931434 )
1996
389
Prospective study of the incidence, timing and treatment of pouchitis in 104 consecutive patients after restorative proctocolectomy. ( 8624195 )
1996
390
Smoking may prevent pouchitis in patients with restorative proctocolectomy for ulcerative colitis. ( 8675087 )
1996
391
Substance P--an underlying factor for pouchitis? Prospective study of substance P- and vasoactive intestinal polypeptide-immunoreactive innervation and mast cells. ( 8769299 )
1996
392
Severe pouchitis successfully treated with short-chain fatty acids. ( 8769932 )
1996
393
Perinuclear antineutrophil cytoplasmic antibody in pouchitis after proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis. ( 8789899 )
1996
394
Pouchitis: pathogenesis, diagnosis, and management. ( 8792143 )
1996
395
Pouchitis following pelvic pouch operation for ulcerative colitis. Incidence, cumulative risk, and risk factors. ( 8797652 )
1996
396
Pouchitis after ileal pouch-anal anastomosis for ulcerative colitis occurs with increased frequency in patients with associated primary sclerosing cholangitis. ( 8801203 )
1996
397
Review article: the management of pouchitis. ( 8853749 )
1996
398
Increased mucosal levels of leukotriene B4 in pouchitis: evidence for a persistent inflammatory state. ( 8900910 )
1996
399
Pouchitis--predictable by immunological or genetic markers? ( 8930555 )
1996
400
Genetic and immunological markers in pouchitis. ( 8930557 )
1996
401
Pouch permeability: breaching barriers to understanding pouchitis? ( 8977355 )
1996
402
Antineutrophil cytoplasmic antibodies in sera from colectomised ulcerative colitis patients and its relation to the presence of pouchitis. ( 8984029 )
1996
403
Perinuclear anti-neutrophil cytoplasmic antibody and refractory pouchitis. A case-control study. ( 7555435 )
1995
404
Pouchitis and neoplasia in the pelvic ileal reservoir. ( 7557109 )
1995
405
Fecal bile acids, short-chain fatty acids, and bacteria after ileal pouch-anal anastomosis do not differ in patients with pouchitis. ( 7628271 )
1995
406
Cytokine production in pouchitis is similar to that in ulcerative colitis. ( 7634977 )
1995
407
Pouchitis: a clarification. ( 7657093 )
1995
408
Pouchitis. ( 7677880 )
1995
409
Faecal alpha 1-antitrypsin concentration in the diagnosis and management of patients with pouchitis. ( 7712304 )
1995
410
Antineutrophil cytoplasmic antibody correlates with chronic pouchitis after ileal pouch-anal anastomosis. ( 7733080 )
1995
411
Acute pouchitis and deficiencies of fuel. ( 7736879 )
1995
412
Pouchitis--a poorly understood entity. ( 7813336 )
1995
413
Pouchitis disease course after orthotopic liver transplantation in patients with primary sclerosing cholangitis and an ileal pouch-anal anastomosis. ( 8540511 )
1995
414
p-ANCA and development of pouchitis in ulcerative colitis patients after proctocolectomy and ileoanal pouch anastomosis. ( 7916418 )
1994
415
Pouchitis. ( 7953327 )
1994
416
Pouchitis following ileal pouch-anal anastomosis: definition, pathogenesis, and treatment. ( 7958702 )
1994
417
Topical metronidazole treatment in pouchitis. ( 8036463 )
1994
418
Pouchitis after ileal pouch-anal anastomosis: a Pouchitis Disease Activity Index. ( 8170189 )
1994
419
Pouchitis and empiricism: can we progress? ( 8170202 )
1994
420
Hypothesis--pouchitis represents a useful clinical model of ulcerative colitis. ( 8196557 )
1994
421
Double-blind crossover trial of metronidazole versus placebo in chronic unremitting pouchitis. ( 8200250 )
1994
422
Pouchitis: result of microbial imbalance? ( 8200561 )
1994
423
Pouchitis--recurrence of the inflammatory bowel disease? ( 8307476 )
1994
424
Incidence and characteristics of pouchitis in the Kock continent ileostomy and the pelvic pouch. ( 8210985 )
1993
425
Cyclosporin A retention enemas in refractory distal ulcerative colitis and 'pouchitis'. ( 8210986 )
1993
426
The pull-through procedure: technical factors in influencing outcome, with emphasis on pouchitis. ( 8211701 )
1993
427
Refractory pouchitis: does it reflect underlying Crohn's disease? ( 8244140 )
1993
428
Mucosal morphology, cell proliferation and faecal bacteriology in acute pouchitis. ( 8252361 )
1993
429
Chronic pouchitis after ileal pouch-anal anastomosis: responses to butyrate and glutamine suppositories in a pilot study. ( 8412364 )
1993
430
The problem with pouchitis. ( 8462812 )
1993
431
Evaluation of the inflammatory infiltrate in pouchitis with 111In-labeled granulocytes. ( 8462824 )
1993
432
Short-chain fatty acids in pouch contents from patients with and without pouchitis after ileal pouch-anal anastomosis. ( 1397871 )
1992
433
Results of pouch surgery after ileo-anal anastomosis: the implications of pouchitis. ( 1462623 )
1992
434
Role of oxygen free radicals in the etiology of pouchitis. ( 1568395 )
1992
435
Macrophage subpopulations in pouchitis. ( 1644321 )
1992
436
Pouchitis--is it a wastebasket diagnosis? ( 1649737 )
1991
437
Pouchitis and extraintestinal manifestations of inflammatory bowel disease after ileal pouch-anal anastomosis. ( 2009019 )
1991
438
Presence of PAF-acether in stool of patients with pouch ileoanal anastomosis and pouchitis. ( 2019356 )
1991
439
Pouchitis following colectomy and ileal reservoir construction for familial adenomatous polyposis. ( 2174708 )
1990
440
Pouchitis and gastric hyposecretion: cause or effect? ( 2170550 )
1990
441
The pelvic ileal reservoir: pathology and pouchitis. ( 2172847 )
1990
442
Inflammation in ileal reservoirs: 'pouchitis'. ( 2182398 )
1990
443
Pouchitis and extraintestinal manifestations of inflammatory bowel disease after ileal pouch-anal anastomosis. ( 2339922 )
1990
444
Ileitis and pouchitis after colectomy for ulcerative colitis. ( 2670050 )
1989
445
Pouchitis (pouch ileitis). ( 2702314 )
1989
446
Pouchitis. ( 2693561 )
1989
447
Short-chain fatty acid irrigation in severe pouchitis. ( 2811955 )
1989
448
Topical administration of 5-aminosalicylic acid: a therapeutic proposal for the treatment of pouchitis. ( 2911318 )
1989
449
Pouchitis. ( 3058838 )
1988
450
Relationship of backwash ileitis to ileal pouchitis after ileal pouch-anal anastomosis. ( 3026757 )
1987
451
Solitary J-pouch ulcer causing pouchitis-like syndrome. ( 3731967 )
1986

Variations for Pouchitis

Expression for Pouchitis

Search GEO for disease gene expression data for Pouchitis.

Pathways for Pouchitis

GO Terms for Pouchitis

Biological processes related to Pouchitis according to GeneCards Suite gene sharing:

(showing 33, show less)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.82 CXCL8 IL10 IL1RN
2 cytokine-mediated signaling pathway GO:0019221 9.78 CXCL8 IL10 IL1RN
3 immune response GO:0006955 9.73 CXCL8 IL10 IL1RN TLR4
4 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.67 LTF NOD2 TLR4
5 defense response to Gram-negative bacterium GO:0050829 9.66 LTF TLR4
6 neutrophil chemotaxis GO:0030593 9.65 CXCL8 IL1RN
7 regulation of inflammatory response GO:0050727 9.65 NOD2 TLR4
8 response to glucocorticoid GO:0051384 9.64 IL10 IL1RN
9 antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 9.64 CXCL8 LTF
10 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.63 NOD2 TLR4
11 positive regulation of tumor necrosis factor production GO:0032760 9.63 NOD2 TLR4
12 interleukin-1-mediated signaling pathway GO:0070498 9.62 IL1RN NOD2
13 negative regulation of tumor necrosis factor production GO:0032720 9.62 IL10 TLR4
14 inflammatory response GO:0006954 9.62 CXCL8 IL10 IL1RN TLR4
15 negative regulation of interferon-gamma production GO:0032689 9.6 IL10 TLR4
16 negative regulation of interleukin-6 production GO:0032715 9.59 IL10 TLR4
17 positive regulation of interleukin-1 beta secretion GO:0050718 9.58 NOD2 TLR4
18 positive regulation of interleukin-8 production GO:0032757 9.58 NOD2 TLR4
19 leukocyte chemotaxis GO:0030595 9.57 CXCL8 IL10
20 positive regulation of interleukin-10 production GO:0032733 9.56 NOD2 TLR4
21 positive regulation of stress-activated MAPK cascade GO:0032874 9.55 NOD2 TLR4
22 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.54 NOD2 TLR4
23 positive regulation of JNK cascade GO:0046330 9.54 IL1RN NOD2 TLR4
24 positive regulation of macrophage activation GO:0043032 9.52 IL10 TLR4
25 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.51 NOD2 TLR4
26 response to molecule of bacterial origin GO:0002237 9.48 CXCL8 IL10
27 negative regulation of heterotypic cell-cell adhesion GO:0034115 9.46 IL10 IL1RN
28 defense response to bacterium GO:0042742 9.46 IL10 LTF NOD2 TLR4
29 positive regulation of interleukin-6 production GO:0032755 9.43 IL1RN NOD2 TLR4
30 positive regulation of MHC class II biosynthetic process GO:0045348 9.4 IL10 TLR4
31 response to activity GO:0014823 9.31 IL10
32 positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 9.26 IL1RN LTF NOD2 TLR4
33 cellular response to lipopolysaccharide GO:0071222 9.02 CXCL8 IL10 IL1RN NOD2 TLR4

Molecular functions related to Pouchitis according to GeneCards Suite gene sharing:

(showing 2, show less)
# Name GO ID Score Top Affiliating Genes
1 lipopolysaccharide binding GO:0001530 8.96 LTF TLR4
2 cytokine activity GO:0005125 8.8 CXCL8 IL10 IL1RN

Sources for Pouchitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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