Powassan Encephalitis

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Disease Ontology 12 DOID:0050179

UMLS 73 C0032858 C1563215

Disease Ontology : ¹² A viral infectious disease that results in inflammation located in brain, has material basis in Powassan virus, which is transmitted by Ixodes and transmitted by Dermacentor species of ticks. The infection has symptom headache, has symptom fever, has symptom vomiting, has symptom stiff neck, has symptom sleepiness, has symptom breathing distress, has symptom tremors, has symptom confusion, has symptom seizures, has symptom paralysis, and has symptom coma.

MalaCards based summary : Powassan Encephalitis, also known as powassan encephalitis virus infection, is related to encephalitis and lyme disease, and has symptoms including headache, fever and vomiting. An important gene associated with Powassan Encephalitis is GAD2 (Glutamate Decarboxylase 2), and among its related pathways/superpathways is Allograft rejection. Affiliated tissues include brain and brain, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Wikipedia : ⁷⁶ Powassan encephalitis, caused by the Powassan virus (POWV), a flavivirus also known as the deer tick... more...

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Synthetic lethal with MLN4924 (a NAE inhibitor)	GR00250-A-1	9.23	CD40LG GAD2
2	Synthetic lethal with MLN4924 (a NAE inhibitor)	GR00250-A-2	9.23	CD40LG GAD2

Search Clinical Trials , NIH Clinical Center for Powassan Encephalitis

Search GEO for disease gene expression data for Powassan Encephalitis.