MCID: PWS001
MIFTS: 22

Powassan Encephalitis

Categories: Infectious diseases

Aliases & Classifications for Powassan Encephalitis

MalaCards integrated aliases for Powassan Encephalitis:

Name: Powassan Encephalitis 12 15 71
Powassan Encephalitis Virus Infection 71

Classifications:



External Ids:

Disease Ontology 12 DOID:0050179
UMLS 71 C0032858 C1563215

Summaries for Powassan Encephalitis

Disease Ontology : 12

MalaCards based summary : Powassan Encephalitis, also known as powassan encephalitis virus infection, is related to colorado tick fever and encephalitis. An important gene associated with Powassan Encephalitis is TLL2 (Tolloid Like 2), and among its related pathways/superpathways is Collagen chain trimerization. Affiliated tissues include brain, eye and salivary gland.

Wikipedia : 74 Powassan encephalitis, caused by the Powassan virus (POWV), a flavivirus also known as the deer tick... more...

Related Diseases for Powassan Encephalitis

Diseases related to Powassan Encephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 13)
# Related Disease Score Top Affiliating Genes
1 colorado tick fever 29.2 TLL2 MEP1B ASTL
2 encephalitis 10.7
3 tick-borne encephalitis 10.4
4 kearns-sayre syndrome 10.3
5 west nile virus 10.1
6 follicular lymphoma 10.1
7 mumps 10.1
8 lyme disease 10.1
9 orchitis 10.1
10 viral encephalitis 10.1
11 viral infectious disease 10.1
12 limbic encephalitis 10.1
13 louping ill 9.0 TLL2 MEP1B MEP1A ASTL

Graphical network of the top 20 diseases related to Powassan Encephalitis:



Diseases related to Powassan Encephalitis

Symptoms & Phenotypes for Powassan Encephalitis

Drugs & Therapeutics for Powassan Encephalitis

Search Clinical Trials , NIH Clinical Center for Powassan Encephalitis

Genetic Tests for Powassan Encephalitis

Anatomical Context for Powassan Encephalitis

MalaCards organs/tissues related to Powassan Encephalitis:

40
Brain, Eye, Salivary Gland

Publications for Powassan Encephalitis

Articles related to Powassan Encephalitis:

(show all 31)
# Title Authors PMID Year
1
Prevalence of Infection and Co-Infection and Presence of Rickettsial Endosymbionts in Ixodes Scapularis (Acari: Ixodidae) in Connecticut, USA. 61
31971489 2020
2
Seroprevalence of Borrelia burgdorferi, B. miyamotoi, and Powassan Virus in Residents Bitten by Ixodes Ticks, Maine, USA. 61
30882312 2019
3
A case of Powassan encephalitis acquired in southern Quebec. 61
30559280 2018
4
Tick⁻Virus⁻Host Interactions at the Cutaneous Interface: The Nidus of Flavivirus Transmission. 61
29986483 2018
5
Fatal Powassan Encephalitis (Deer Tick Virus, Lineage II) in a Patient With Fever and Orchitis Receiving Rituximab. 61
29554185 2018
6
First confirmed case of Powassan neuroinvasive disease in Rhode Island. 61
29942757 2018
7
The eye and tick-borne disease in the United States. 61
27585218 2016
8
Interaction of Flaviviruses with Reproduction Inhibitors Binding in β-OG Pocket: Insights from Molecular Dynamics Simulations. 61
27485304 2014
9
The prevalence of zoonotic tick-borne pathogens in Ixodes scapularis collected in the Hudson Valley, New York State. 61
24689680 2014
10
Potential role of deer tick virus in Powassan encephalitis cases in Lyme disease-endemic areas of New York, U.S.A. 61
24274334 2013
11
Changing epidemiology of Powassan encephalitis in North America suggests the emergence of the deer tick virus subtype. 61
24124795 2013
12
Early immunologic events at the tick-host interface. 61
23077588 2012
13
Supranuclear ophthalmoplegia in Powassan encephalitis. 61
20929710 2010
14
Tick (Acari: Ixodidae) infestation at two rural, seasonal camps in Maine and Vermont. 61
19925041 2010
15
Zoonotic tick-borne flaviviruses. 61
19765917 2010
16
Increased recognition of Powassan encephalitis in the United States, 1999-2005. 61
18959500 2008
17
Powassan encephalitis and Colorado tick fever. 61
18755390 2008
18
Transcriptome analysis of the salivary glands of Dermacentor andersoni Stiles (Acari: Ixodidae). 61
17175446 2007
19
Tick-borne encephalopathies : epidemiology, diagnosis, treatment and prevention. 61
16332143 2005
20
Ophthalmoplegia in Powassan encephalitis. 61
12771287 2003
21
From the Centers for Disease Control and Prevention. Outbreak of Powassan encephalitis--Maine and Vermont, 1999-2001. 61
11693145 2001
22
Outbreak of Powassan encephalitis--Maine and Vermont, 1999-2001. 61
11787585 2001
23
Powassan encephalitis. 61
10906898 1999
24
Powassan encephalitis: a case report with neuropathology and literature review. 61
10906899 1999
25
Arboviral disease--United States, 1994. 61
7643850 1995
26
Diversity of tick species biting humans in an emerging area for Lyme disease. 61
1536337 1992
27
[The clinico-epidemiological characteristics of Powassan encephalitis in the southern Soviet Far East]. 61
1651637 1991
28
Powassan encephalitis in new brunswick. 61
21233909 1990
29
[Tick-borne encephalitis in the Maritime Territory]. 61
2816183 1989
30
[The role of wild murine rodents in the selection of different strains of tick-borne encephalitis and Powassan viruses]. 61
2829440 1987
31
Arbovirus infections in man in British Columbia. 61
5034698 1972

Variations for Powassan Encephalitis

Expression for Powassan Encephalitis

Search GEO for disease gene expression data for Powassan Encephalitis.

Pathways for Powassan Encephalitis

Pathways related to Powassan Encephalitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.65 TLL2 TLL1 MEP1B MEP1A

GO Terms for Powassan Encephalitis

Cellular components related to Powassan Encephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 meprin A complex GO:0017090 8.62 MEP1B MEP1A

Biological processes related to Powassan Encephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 proteolysis GO:0006508 9.02 TLL2 TLL1 MEP1B MEP1A ASTL
2 extracellular matrix disassembly GO:0022617 8.96 TLL2 TLL1

Molecular functions related to Powassan Encephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hydrolase activity GO:0016787 9.72 TLL2 TLL1 MEP1B MEP1A ASTL
2 zinc ion binding GO:0008270 9.65 TLL2 TLL1 MEP1B MEP1A ASTL
3 peptidase activity GO:0008233 9.55 TLL2 TLL1 MEP1B MEP1A ASTL
4 metallopeptidase activity GO:0008237 9.35 TLL2 TLL1 MEP1B MEP1A ASTL
5 metalloendopeptidase activity GO:0004222 9.02 TLL2 TLL1 MEP1B MEP1A ASTL

Sources for Powassan Encephalitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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