MCID: PRR018
MIFTS: 14

Preauricular Sinus

Categories: Rare diseases

Aliases & Classifications for Preauricular Sinus

MalaCards integrated aliases for Preauricular Sinus:

Name: Preauricular Sinus 53

Classifications:



Summaries for Preauricular Sinus

NIH Rare Diseases : 53 Preauricular sinus is a common birth defect that may be seen during a routine exam of a newborn. It generally appears as a tiny skin-lined hole or pit, often just in front of the upper ear where the cartilage of the ear rim meets the face. It may occur on one side (unilateral) or both sides (bilateral) of the ear. Affected people usually do not have any additional symptoms unless it becomes infected. Preauricular sinus may occur sporadically during the development of an embryo or it may be inherited in an autosomal dominant manner with reduced penetrance. Less often, it occurs as a feature of another condition or syndrome. Treatment may include antibiotics for infection and/or surgery to remove the sinus.

MalaCards based summary : Preauricular Sinus is related to hypertelorism, preauricular sinus, punctal pits, and deafness and external ear disease. An important gene associated with Preauricular Sinus is HPPD (Hypertelorism, Preauricular Sinus, Punctal Pits, And Deafness). Affiliated tissues include skin.

Related Diseases for Preauricular Sinus

Diseases related to Preauricular Sinus via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 11)
# Related Disease Score Top Affiliating Genes
1 hypertelorism, preauricular sinus, punctal pits, and deafness 12.3
2 external ear disease 11.2
3 hemangioma of subcutaneous tissue 9.8
4 microtia 9.8
5 commissural lip pits 9.8
6 hypertelorism 9.8
7 steatocystoma multiplex 9.8
8 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 9.8
9 hemangioma 9.8
10 nephrolithiasis 9.8
11 arteriovenous malformation 9.8

Graphical network of the top 20 diseases related to Preauricular Sinus:



Diseases related to Preauricular Sinus

Symptoms & Phenotypes for Preauricular Sinus

Drugs & Therapeutics for Preauricular Sinus

Search Clinical Trials , NIH Clinical Center for Preauricular Sinus

Genetic Tests for Preauricular Sinus

Anatomical Context for Preauricular Sinus

MalaCards organs/tissues related to Preauricular Sinus:

41
Skin

Publications for Preauricular Sinus

Articles related to Preauricular Sinus:

(show top 50) (show all 52)
# Title Authors Year
1
Ectopic Preauricular Sinus in a Facial Cleft and Microtia Patient. ( 29349057 )
2017
2
The clinical efficacy of early intervention for infected preauricular sinus. ( 28576531 )
2017
3
A systematic review on the surgical outcome of preauricular sinus excision techniques. ( 27320109 )
2016
4
Intralesional triamcinolone injections for the treatment of preauricular sinus infections. ( 27567384 )
2016
5
A Surgical Technique for Congenital Preauricular Sinus. ( 28913224 )
2015
6
Reconstruction techniques for tissue defects formed after preauricular sinus excision. ( 24511494 )
2014
7
Congenital periauricular fistulas: Possible variants of the preauricular sinus. ( 25190621 )
2014
8
Analysis of incidence and genetic predisposition of preauricular sinus. ( 25465450 )
2014
9
The prevalence of preauricular sinus and associated factors in a nationwide population-based survey of South Korea. ( 25251303 )
2014
10
Surgical Site Infection due to a Preauricular Sinus: A Rare Complication after Craniotomy. ( 25426340 )
2014
11
A case of subcutaneous hemangioma presenting as a preauricular sinus. ( 24653902 )
2013
12
Presentation of preauricular sinus and preauricular sinus abscess in southwest Nigeria. ( 24711764 )
2013
13
Preauricular sinus: a novel approach. ( 24427573 )
2013
14
Early one-stage surgical treatment of infected preauricular sinus. ( 23543320 )
2013
15
Preauricular sinus: advantage of the drainless minimal supra-auricular approach. ( 22133968 )
2012
16
Preauricular sinus, nephrolithiasis, infantine eczema and natal tooth: a new association. ( 21398203 )
2011
17
HPPD: A newly recognized autosomal dominant disorder involving hypertelorism, preauricular sinus, punctal pits, and deafness mapping to chromosome 14q31. ( 21480481 )
2011
18
Radiofrequency thermal ablation versus 'cold steel' for supra-auricular excision of preauricular sinus: comparative study. ( 20537204 )
2010
19
Pressure dressing after excision of preauricular sinus: suture transfixion of silicone sheets. ( 19796437 )
2009
20
Postoperative drainage with a vacutainer tube after excision of the preauricular sinus. ( 19260901 )
2009
21
Re: Postoperative drainage with a vacutainer tube after excision of the preauricular sinus. ( 19531193 )
2009
22
Report of a scalp arteriovenous malformation spontaneously hemorrhaging into a preauricular sinus. ( 19224470 )
2009
23
Surgical treatment of recurring preauricular sinus: supra-auricular approach. ( 19205595 )
2008
24
The variant type of preauricular sinus: postauricular sinus. ( 17713452 )
2007
25
Outcome of patients presenting with preauricular sinus in a tertiary centre--a five year experience. ( 17682572 )
2007
26
Preauricular sinus: clinical course and associations. ( 17224527 )
2007
27
The preauricular sinus: factors contributing to recurrence after surgery. ( 17084223 )
2006
28
Preauricular sinus: Operating microscope improves outcome. ( 23120226 )
2006
29
A new surgical technique for treatment of preauricular sinus. ( 15855931 )
2005
30
The preauricular sinus: A review of its aetiology, clinical presentation and management. ( 16125253 )
2005
31
A safe and reliable technique in the management of preauricular sinus. ( 23120197 )
2005
32
An insidious preauricular sinus presenting as an infected postauricular cyst. ( 15857338 )
2005
33
The preauricular sinus: a review of its clinical presentation, treatment, and associations. ( 15165194 )
2004
34
Management of an infected preauricular sinus, using a lacrimal probe. ( 14738611 )
2003
35
Facial steatocystoma multiplex associated with pilar cyst and bilateral preauricular sinus. ( 11990251 )
2002
36
Excision of the preauricular sinus: a comparison of two surgical techniques. ( 11210882 )
2001
37
Sonographic appearances of preauricular sinus. ( 10924376 )
2000
38
Management of the preauricular sinus. ( 11284143 )
1999
39
The excised preauricular sinus in 14 years of experience: is there a problem? ( 9773994 )
1998
40
Preauricular sinus as a cause of wound infection after rhytidectomy. ( 9703110 )
1998
41
Single stage excision of preauricular sinus. ( 7717944 )
1995
42
Congenital conductive or mixed deafness, preauricular sinus, external ear anomaly, and commissural lip pits: an autosomal dominant inherited syndrome. ( 1746829 )
1991
43
Excision of preauricular sinus. ( 2248752 )
1990
44
Epidermal cyst originating from the preauricular sinus. ( 3809273 )
1987
45
The management of preauricular sinus. ( 6581417 )
1984
46
Towards better delineation and complete excision of preauricular sinus. ( 6576778 )
1983
47
An unusual impacted inverted molar in mandibular condyle with preauricular sinus (a case report). ( 6964364 )
1982
48
Surgical treatment of the infected preauricular sinus. ( 435171 )
1979
49
Genetic hearing loss with preauricular sinus and branchiogenic fistula. ( 921599 )
1977
50
Subcondylar impaction of a third molar resulting in chronic preauricular sinus: report of case. ( 4500327 )
1972

Variations for Preauricular Sinus

Expression for Preauricular Sinus

Search GEO for disease gene expression data for Preauricular Sinus.

Pathways for Preauricular Sinus

GO Terms for Preauricular Sinus

Sources for Preauricular Sinus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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