MCID: PRD001
MIFTS: 26

Predominantly Cortical Thymoma

Categories: Cancer diseases, Immune diseases, Endocrine diseases, Blood diseases

Aliases & Classifications for Predominantly Cortical Thymoma

MalaCards integrated aliases for Predominantly Cortical Thymoma:

Name: Predominantly Cortical Thymoma 12 15
Lymphocyte-Predominant Thymoma 12
Thymoma, Organoid 12
Thymoma, Type B1 73

Classifications:



External Ids:

Disease Ontology 12 DOID:6917
NCIt 50 C6887
SNOMED-CT 68 128711009
UMLS 73 C1266094

Summaries for Predominantly Cortical Thymoma

MalaCards based summary : Predominantly Cortical Thymoma, also known as lymphocyte-predominant thymoma, is related to breast squamous cell carcinoma and odontoma. An important gene associated with Predominantly Cortical Thymoma is KRT14 (Keratin 14), and among its related pathways/superpathways are Keratinization and Circadian entrainment. Related phenotypes are digestive/alimentary and endocrine/exocrine gland

Related Diseases for Predominantly Cortical Thymoma

Diseases related to Predominantly Cortical Thymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 103)
# Related Disease Score Top Affiliating Genes
1 breast squamous cell carcinoma 10.5 KRT14 PGR
2 odontoma 10.4 KRT14 KRT19
3 limbal stem cell deficiency 10.4 KRT14 KRT19
4 lipoadenoma 10.4 KRT14 KRT19
5 vulvar syringoma 10.4 ESR1 PGR
6 lung leiomyoma 10.4 ESR1 PGR
7 vestibular gland benign neoplasm 10.4 ESR1 PGR
8 bartholin's gland adenoma 10.4 ESR1 PGR
9 glassy cell carcinoma of the cervix 10.4 ESR1 PGR
10 vulvar benign neoplasm 10.4 ESR1 PGR
11 trigonitis 10.4 ESR1 PGR
12 vulvar leiomyoma 10.4 ESR1 PGR
13 breast medullary carcinoma 10.4 ESR1 PGR
14 breast scirrhous carcinoma 10.4 ESR1 PGR
15 progesterone resistance 10.4 ESR1 PGR
16 progesterone-receptor positive breast cancer 10.4 ESR1 PGR
17 cribriform carcinoma 10.4 ESR1 PGR
18 endometrial squamous cell carcinoma 10.4 ESR1 PGR
19 gastric signet ring cell adenocarcinoma 10.4 ESR1 PGR
20 endometrial mucinous adenocarcinoma 10.4 ESR1 PGR
21 epidural neoplasm 10.4 KRT19 PTPRC
22 adenoid basal cell carcinoma 10.4 ESR1 PGR
23 apocrine adenocarcinoma 10.4 ESR1 PGR
24 intraneural perineurioma 10.4 KRT14 KRT19
25 gender identity disorder 10.4 ESR1 PGR
26 bartholin's gland benign neoplasm 10.4 ESR1 PGR
27 deep angioma 10.4 ESR1 PGR
28 synchronous bilateral breast carcinoma 10.4 ESR1 PGR
29 corneal abscess 10.3 KRT19 PGR
30 breast adenoid cystic carcinoma 10.3 ESR1 PGR
31 immune system organ benign neoplasm 10.3 KRT19 PTPRC
32 cervical carcinosarcoma 10.3 ESR1 PGR
33 thymus lipoma 10.3 KRT19 PTPRC
34 estrogen excess 10.3 ESR1 PGR
35 intramuscular hemangioma 10.3 ESR1 PGR
36 pinguecula 10.3 KRT14 KRT19
37 glycogen-rich clear cell breast carcinoma 10.3 ESR1 PGR
38 mammographic density 10.3 ESR1 PGR
39 retinitis pigmentosa 47 10.3 ESR1 PGR
40 uterine corpus cancer 10.3 ESR1 PGR
41 adenomyosis 10.3 ESR1 PGR
42 retinitis pigmentosa 20 10.3 ESR1 PGR
43 luminal breast carcinoma 10.3 ESR1 PGR
44 adenosarcoma 10.3 ESR1 PGR
45 white sponge nevus 1 10.3 KRT14 KRT19
46 endometriosis of ovary 10.3 ESR1 PGR
47 inflammatory breast carcinoma 10.3 ESR1 PGR
48 mixed cell type cancer 10.3 ESR1 PGR
49 primary cutaneous amyloidosis 10.3 KRT14 KRT19
50 smooth muscle tumor 10.3 ESR1 PGR

Graphical network of the top 20 diseases related to Predominantly Cortical Thymoma:



Diseases related to Predominantly Cortical Thymoma

Symptoms & Phenotypes for Predominantly Cortical Thymoma

MGI Mouse Phenotypes related to Predominantly Cortical Thymoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.77 PDPN PTPRC ESR1 KRT14 KRT19
2 endocrine/exocrine gland MP:0005379 9.72 KRT19 PGR PTPRC ESR1 KRT14
3 integument MP:0010771 9.65 PDPN PGR ESR1 KRT14 KRT19
4 neoplasm MP:0002006 9.55 PGR PTPRC ESR1 KRT14 KRT19
5 no phenotypic analysis MP:0003012 9.26 KRT19 PGR PTPRC ESR1
6 skeleton MP:0005390 9.02 KRT19 PDPN PGR PTPRC ESR1

Drugs & Therapeutics for Predominantly Cortical Thymoma

Search Clinical Trials , NIH Clinical Center for Predominantly Cortical Thymoma

Genetic Tests for Predominantly Cortical Thymoma

Anatomical Context for Predominantly Cortical Thymoma

Publications for Predominantly Cortical Thymoma

Variations for Predominantly Cortical Thymoma

Expression for Predominantly Cortical Thymoma

Search GEO for disease gene expression data for Predominantly Cortical Thymoma.

Pathways for Predominantly Cortical Thymoma

Pathways related to Predominantly Cortical Thymoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.79 IVL KRT14 KRT19
2
Show member pathways
11.79 ESR1 KRT14 KRT19 PGR
3 10.5 ESR1 KRT19

GO Terms for Predominantly Cortical Thymoma

Biological processes related to Predominantly Cortical Thymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to estrogen GO:0043627 9.26 ESR1 KRT19
2 steroid hormone mediated signaling pathway GO:0043401 9.16 ESR1 PGR
3 keratinization GO:0031424 9.13 IVL KRT14 KRT19
4 cornification GO:0070268 8.8 IVL KRT14 KRT19

Molecular functions related to Predominantly Cortical Thymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ATPase binding GO:0051117 9.26 ESR1 PGR
2 steroid hormone receptor activity GO:0003707 9.16 ESR1 PGR
3 nuclear receptor activity GO:0004879 8.96 ESR1 PGR
4 steroid binding GO:0005496 8.62 ESR1 PGR

Sources for Predominantly Cortical Thymoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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