MCID: PRD001
MIFTS: 22

Predominantly Cortical Thymoma

Categories: Blood diseases, Cancer diseases, Immune diseases

Aliases & Classifications for Predominantly Cortical Thymoma

MalaCards integrated aliases for Predominantly Cortical Thymoma:

Name: Predominantly Cortical Thymoma 12 15
Lymphocyte-Predominant Thymoma 12
Thymoma, Organoid 12
Thymoma, Type B1 70

Classifications:



External Ids:

Disease Ontology 12 DOID:6917
NCIt 50 C6887
SNOMED-CT 67 128711009
UMLS 70 C1266094

Summaries for Predominantly Cortical Thymoma

MalaCards based summary : Predominantly Cortical Thymoma, also known as lymphocyte-predominant thymoma, is related to malignant histiocytic disease and central nervous system sarcoma. An important gene associated with Predominantly Cortical Thymoma is DLEU1 (Deleted In Lymphocytic Leukemia 1), and among its related pathways/superpathways are Amoebiasis and Hematopoietic cell lineage. Affiliated tissues include thyroid.

Related Diseases for Predominantly Cortical Thymoma

Diseases related to Predominantly Cortical Thymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 56)
# Related Disease Score Top Affiliating Genes
1 malignant histiocytic disease 9.9 CD1E CD1A
2 central nervous system sarcoma 9.9 CD1E CD1A
3 mycobacterium malmoense 9.9 CD1E CD1A
4 lichen nitidus 9.9 CD1E CD1A
5 mixed type thymoma 9.9 CD1E CD1A
6 encapsulated thymoma 9.9 CD1E CD1A
7 phlyctenulosis 9.9 CD1E CD1A
8 sphenoid sinusitis 9.9 CD1E CD1A
9 chronic laryngitis 9.9 CD1E CD1A
10 tolosa-hunt syndrome 9.9 CD1E CD1A
11 rhinoscleroma 9.9 CD1E CD1A
12 reticulohistiocytic granuloma 9.9 CD1E CD1A
13 inflamed seborrheic keratosis 9.9 CD1E CD1A
14 balloon cell malignant melanoma 9.9 CD1E CD1A
15 multifocal motor neuropathy 9.9 CD1E CD1A
16 langerhans cell sarcoma 9.9 CD1E CD1A
17 keratoacanthoma 9.9 IVL CD1A
18 spongiotic dermatitis 9.9 CD1E CD1A
19 necrobiosis lipoidica 9.9 CD1E CD1A
20 interdigitating dendritic cell sarcoma 9.9 CD1E CD1A
21 diencephalic astrocytoma 9.9 CD1E CD1A
22 orbital cancer 9.8 CD1E CD1A
23 granuloma annulare 9.8 CD1E CD1A
24 marginal corneal ulcer 9.8 CD1E CD1A
25 oral hairy leukoplakia 9.8 CD1E CD1A
26 histiocytic and dendritic cell cancer 9.8 CD1E CD1A
27 pityriasis rosea 9.8 CD1E CD1A
28 kimura disease 9.8 CD1E CD1A
29 non-langerhans-cell histiocytosis 9.8 CD1E CD1A
30 lichen planus 9.8 IVL CD1A
31 central epithelioid sarcoma 9.8 CD1E CD1A
32 vulvar proximal-type epithelioid sarcoma 9.8 CD1E CD1A
33 polyclonal hypergammaglobulinemia 9.8 CD1E CD1A
34 pilar sheath acanthoma 9.8 CD1E CD1A
35 acanthoma 9.8 CD1E CD1A
36 diencephalic neoplasm 9.8 CD1E CD1A
37 adult xanthogranuloma 9.8 CD1E CD1A
38 juvenile xanthogranuloma 9.8 CD1E CD1A
39 erdheim-chester disease 9.8 CD1E CD1A
40 psoriasis 15 9.8 CD1E CD1A
41 seborrheic dermatitis 9.8 CD1E CD1A
42 fibrosarcoma of bone 9.8 CD1E CD1A
43 histiocytosis-lymphadenopathy plus syndrome 9.8 CD1E CD1A
44 lichen disease 9.8 CD1E CD1A
45 exophthalmos 9.8 CD1E CD1A
46 diabetes insipidus, neurohypophyseal 9.7 CD1E CD1A
47 folliculitis 9.7 CD1E CD1A
48 connective tissue benign neoplasm 9.7 CD1E CD1A
49 leprosy 3 9.6 CD1E CD1A
50 myasthenia gravis 9.6 CHRNA1 AIRE

Graphical network of the top 20 diseases related to Predominantly Cortical Thymoma:



Diseases related to Predominantly Cortical Thymoma

Symptoms & Phenotypes for Predominantly Cortical Thymoma

Drugs & Therapeutics for Predominantly Cortical Thymoma

Search Clinical Trials , NIH Clinical Center for Predominantly Cortical Thymoma

Genetic Tests for Predominantly Cortical Thymoma

Anatomical Context for Predominantly Cortical Thymoma

MalaCards organs/tissues related to Predominantly Cortical Thymoma:

40
Thyroid

Publications for Predominantly Cortical Thymoma

Articles related to Predominantly Cortical Thymoma:

(show all 17)
# Title Authors PMID Year
1
Development of BCR-ABL1-positive ɤδ T-cell leukemia after treatment for thymoma type B1. 61
33284042 2020
2
An Unusual Invasive Ectopic Thymoma in the Thyroid and Anterior Mediastinum. 61
29626459 2018
3
Ectopic thymoma presenting as a large intrathoracic mass. 61
26881626 2015
4
Aspiration cytology of an ectopic cervical thymoma misinterpreted as a lymphoproliferative lesion of the thyroid: A case report. 61
26622659 2015
5
Ovarian Metastasis of a Thymoma: Report of a Case and Literature Review. 61
26061071 2015
6
Thymoma type B1 arising in a giant supradiaphragmatic thymolipoma. 61
24887884 2014
7
Ectopic Pleural Thymoma : Report of a case. 61
26021544 2014
8
Paraneoplastic encephalitis associated with thymoma: a case report. 61
23772416 2013
9
Clinical, morphological and immunohistochemical characterization of a recurrent B1 type thymoma. 61
22990560 2012
10
A malignant retroperitoneal mass--a rare presentation of recurrent thymoma. 61
22674945 2011
11
[Surgical resection with adjuvant chemotherapy for locally advanced Masaoka stage IVa thymoma; report of a case]. 61
20214360 2010
12
[Thymoma with long-term survival treated by polysurgery; report of a case]. 61
19670792 2009
13
Recurrent thymoma: radiological (CT and FDG-PET) and histological (WHO criteria) features. 61
16958404 2006
14
Long-term outcome after multimodality treatment for stage III thymic tumors. 61
14667602 2003
15
Evaluation of the malignant grade of thymic epithelial tumors according to the epithelial subclassification. 61
10648082 2000
16
Recurrent thymoma: evidence for histological progression. 61
8575735 1995
17
Thymoma--morphologic subclassification correlates with invasiveness and immunohistologic features: a study of 122 cases. 61
8253462 1993

Variations for Predominantly Cortical Thymoma

Expression for Predominantly Cortical Thymoma

Search GEO for disease gene expression data for Predominantly Cortical Thymoma.

Pathways for Predominantly Cortical Thymoma

Pathways related to Predominantly Cortical Thymoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.96 CD1E CD1A
2 10.62 CD1E CD1A

GO Terms for Predominantly Cortical Thymoma

Biological processes related to Predominantly Cortical Thymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.43 CD1E CD1A AIRE
2 positive regulation of T cell mediated cytotoxicity GO:0001916 9.16 CD1E CD1A
3 antigen processing and presentation, exogenous lipid antigen via MHC class Ib GO:0048007 8.96 CD1E CD1A
4 antigen processing and presentation, endogenous lipid antigen via MHC class Ib GO:0048006 8.62 CD1E CD1A

Molecular functions related to Predominantly Cortical Thymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lipopeptide binding GO:0071723 9.16 CD1E CD1A
2 exogenous lipid antigen binding GO:0030884 8.96 CD1E CD1A
3 endogenous lipid antigen binding GO:0030883 8.62 CD1E CD1A

Sources for Predominantly Cortical Thymoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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