MCID: PRM020
MIFTS: 53

Premenstrual Tension

Categories: Reproductive diseases

Aliases & Classifications for Premenstrual Tension

MalaCards integrated aliases for Premenstrual Tension:

Name: Premenstrual Tension 12 15 74
Premenstrual Syndrome 45 74 64

Classifications:



External Ids:

Disease Ontology 12 DOID:727
ICD9CM 36 625.4
MeSH 45 D011293
SNOMED-CT 69 82639001
ICD10 34 N94.3

Summaries for Premenstrual Tension

PubMed Health : 64 About premenstrual syndrome: In the days leading up to their period, many women experience abdominal pain or a headache, are sad and irritable or feel bloated and generally uncomfortable. The medical term for this is “premenstrual syndrome” (PMS), also known as “premenstrual tension” (PMT). PMS symptoms are usually not very severe, and most women cope well with them. But in some women it is so bad that they are unable to go about their everyday lives during that time. Various treatments and measures can help to relieve PMS.

MalaCards based summary : Premenstrual Tension, also known as premenstrual syndrome, is related to anovulation and postpartum depression, and has symptoms including pelvic pain, pain and other symptoms associated with female genital organs and mittelschmerz. An important gene associated with Premenstrual Tension is GNRH1 (Gonadotropin Releasing Hormone 1), and among its related pathways/superpathways are Nongenotropic Androgen signaling and Glucocorticoid Pathway (HPA Axis), Pharmacodynamics. The drugs Estradiol and Polyestradiol phosphate have been mentioned in the context of this disorder. Affiliated tissues include breast, testes and skin, and related phenotypes are homeostasis/metabolism and hematopoietic system

Wikipedia : 77 Premenstrual syndrome (PMS) refers to physical and emotional symptoms that occur in the one to two weeks... more...

Related Diseases for Premenstrual Tension

Diseases related to Premenstrual Tension via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 160)
# Related Disease Score Top Affiliating Genes
1 anovulation 30.2 GNRH1 PRL SHBG
2 postpartum depression 30.2 CRH OXT PRL
3 disease of mental health 30.0 CRH OXT POMC
4 sexual disorder 30.0 OXT PRL SHBG
5 breast disease 29.7 PGR POMC PRL SHBG
6 pre-eclampsia 29.7 CRH OXT REN SERPINE1
7 amenorrhea 29.6 CRH GNRH1 POMC PRL SHBG
8 anorexia nervosa 29.6 CRH OXT POMC PRL
9 acute adrenal insufficiency 10.4 POMC REN
10 hypoaldosteronism 10.4 POMC REN
11 perinephritis 10.4 MGAM REN
12 allergic encephalomyelitis 10.4 CRH POMC
13 myofascial pain syndrome 10.4 CAMP POMC
14 central nervous system germinoma 10.4 AVP POMC
15 gangliocytoma 10.4 CRH POMC
16 tuberculous epididymitis 10.4 AVP POMC
17 mineral metabolism disease 10.3 MGAM POMC REN
18 malignant hypertensive renal disease 10.3 REN SERPINE1
19 malignant renovascular hypertension 10.3 REN SERPINE1
20 adenohypophysitis 10.3 POMC PRL
21 pneumothorax 10.3 FLCN GNRH1 PGR
22 central nervous system germ cell tumor 10.3 AVP POMC
23 hypogonadotropism 10.3 GNRH1 PRL
24 intracystic papillary adenoma 10.3 PGR PRL
25 adrenal cortical hypofunction 10.3 CRH POMC REN
26 lung oat cell carcinoma 10.3 AVP POMC
27 bronchus cancer 10.3 AVP POMC
28 benign essential hypertension 10.3 AVP MGAM REN
29 pituitary infarct 10.3 GNRH1 POMC PRL
30 retroperitoneal leiomyosarcoma 10.3 PGR REN
31 adrenal gland disease 10.3 CRH POMC REN
32 chiasmal syndrome 10.3 GNRH1 POMC PRL
33 pituitary apoplexy 10.3 GNRH1 POMC PRL
34 suprasellar meningioma 10.3 PGR POMC
35 malignant secondary hypertension 10.3 REN SERPINE1
36 empty sella syndrome 10.3 GNRH1 POMC PRL
37 inappropriate adh syndrome 10.3 AVP POMC REN
38 adrenal adenoma 10.3 CRH POMC REN
39 tsh producing pituitary tumor 10.3 GNRH1 POMC PRL
40 space motion sickness 10.3 AVP MGAM REN
41 adrenal carcinoma 10.3 CRH POMC REN
42 acth deficiency, isolated 10.3 CRH POMC
43 adrenal rest tumor 10.3 GNRH1 POMC PRL
44 aortic valve disease 1 10.3 LRP5 POMC REN
45 hypoadrenalism 10.3 CRH POMC SHBG
46 tuberculous empyema 10.3 POMC SERPINE1
47 sella turcica neoplasm 10.2 PGR POMC PRL
48 tuberculum sellae meningioma 10.2 PGR POMC PRL
49 endocrine organ benign neoplasm 10.2 POMC PRL REN
50 pituitary carcinoma 10.2 CRH POMC PRL

Graphical network of the top 20 diseases related to Premenstrual Tension:



Diseases related to Premenstrual Tension

Symptoms & Phenotypes for Premenstrual Tension

UMLS symptoms related to Premenstrual Tension:


pelvic pain, pain and other symptoms associated with female genital organs, mittelschmerz, unspecified symptom associated with female genital organs, other specified symptoms associated with female genital organs, female genital pain and other symptoms

MGI Mouse Phenotypes related to Premenstrual Tension:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.28 AVP CRH FLCN GNRH1 HP LIPN
2 hematopoietic system MP:0005397 10.13 CAMP CRH FLCN GNRH1 HP LRP5
3 cardiovascular system MP:0005385 10.11 FLCN HP LRP5 OXT PGR PNN
4 immune system MP:0005387 10.11 CAMP CRH FLCN GNRH1 HP LRP5
5 integument MP:0010771 9.97 CRH GNRH1 OXT PGR PNN POMC
6 mortality/aging MP:0010768 9.93 AVP CAMP FLCN HP LRP5 OXT
7 liver/biliary system MP:0005370 9.8 CRH GNRH1 HP LRP5 POMC PRL
8 neoplasm MP:0002006 9.5 FLCN GNRH1 HP PGR POMC PRL
9 renal/urinary system MP:0005367 9.28 AVP CRH FLCN GNRH1 HP OXT

Drugs & Therapeutics for Premenstrual Tension

PubMedHealth treatment related to Premenstrual Tension: 64

There isn’t much good research on what can help reduce PMS. So it isn’t clear how effective many of the PMS treatments are.Girls and women with PMS often try out different things to reduce their symptoms. For instance, some women with mild PMS try out relaxation techniques, acupuncture, getting more exercise, drinking less alcohol and coffee, or eating less salt. Others use herbal products and dietary supplements such as chaste tree extracts (Vitex agnus castus), St. John’s wort, calcium or pyridoxine vitamin B6).More severe PMS can be treated with a number of medications. But many of these medications haven’t been approved for the treatment of PMS, and they can have side effects:Hormone medications like the birth control pill or hormone patches affect women’s hormone levels and lead to an improvement in PMS or PMDD.Antidepressants: SSRIs (selective serotonin reuptake inhibitors) can help reduce severe psychological problems caused by PMS or PMDD.Painkillers can effectively relieve severe period pain and are usually well tolerated. There is very little research on whether they also help in PMS, though.Women who have problems with PMS-related water retention can take diuretics (water pills).If PMS causes psychological problems, cognitive behavioral therapy (CBT) is an option. But it isn’t clear whether it helps in PMS.

Drugs for Premenstrual Tension (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 199)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-28-2 5757
2
Polyestradiol phosphate Approved Phase 4,Phase 3,Phase 2,Not Applicable 28014-46-2
3
Ethinyl Estradiol Approved Phase 4,Phase 3,Phase 2,Not Applicable 57-63-6 5991
4
Drospirenone Approved Phase 4,Phase 3,Phase 2,Not Applicable 67392-87-4 68873
5
Fluoxetine Approved, Vet_approved Phase 4,Phase 3,Not Applicable 54910-89-3 3386
6
Progesterone Approved, Vet_approved Phase 4,Phase 2 57-83-0 5994
7
Flutamide Approved, Investigational Phase 4 13311-84-7 3397
8
Guanfacine Approved, Investigational Phase 4 29110-47-2 3519
9
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
10
Dopamine Approved Phase 4 62-31-7, 51-61-6 681
11
Methylphenidate Approved, Investigational Phase 4 113-45-1 4158
12
Risperidone Approved, Investigational Phase 4 106266-06-2 5073
13
Sertraline Approved Phase 4,Phase 1,Phase 2 79617-96-2 68617
14
Desogestrel Approved Phase 4 54024-22-5 40973
15
Paroxetine Approved, Investigational Phase 4,Phase 3 61869-08-7 43815
16
Leuprolide Approved, Investigational Phase 4 53714-56-0 657181 3911
17
Salmon Calcitonin Approved, Investigational Phase 4 47931-85-1 16129616
18
Hydrocortisone acetate Approved, Vet_approved Phase 4 50-03-3
19
Sumatriptan Approved, Investigational Phase 4,Phase 3 103628-46-2 5358
20
Naproxen Approved, Vet_approved Phase 4,Phase 3,Not Applicable 22204-53-1 156391 1302
21
Dinoprostone Approved Phase 4 363-24-6 5280360
22
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754
23
Eletriptan Approved, Investigational Phase 4 143322-58-1 77993
24
Frovatriptan Approved, Investigational Phase 4 158747-02-5 77992
25
Simvastatin Approved Phase 4 79902-63-9 54454
26
Nicotine Approved Phase 4 54-11-5 942 89594
27
Citalopram Approved Phase 4 59729-33-8 2771
28 Tezosentan Investigational Phase 4 180384-57-0
29
Calcitonin gene-related peptide Investigational Phase 4 83652-28-2
30 Fibrinolytic Agents Phase 4
31 Contraceptive Agents Phase 4,Phase 3,Phase 2,Not Applicable
32 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
33 Contraceptives, Oral Phase 4,Phase 3,Phase 2,Not Applicable
34 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
35 Estradiol 17 beta-cypionate Phase 4,Phase 3,Phase 2,Not Applicable
36 Estradiol 3-benzoate Phase 4,Phase 3,Phase 2,Not Applicable
37 Estrogens Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
38 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
39 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 1
40 Androgens Phase 4,Phase 3
41 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
42 Neurotransmitter Uptake Inhibitors Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
43 Serotonin Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
44 Psychotropic Drugs Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
45 Serotonin Uptake Inhibitors Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
46 Antidepressive Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
47 Mineralocorticoid Receptor Antagonists Phase 4,Phase 3,Phase 2,Not Applicable
48 Natriuretic Agents Phase 4,Phase 3,Phase 2,Not Applicable
49 Mineralocorticoids Phase 4,Phase 3,Phase 2,Not Applicable
50 Drospirenone and ethinyl estradiol combination Phase 4,Phase 3,Phase 2,Not Applicable

Interventional clinical trials:

(show top 50) (show all 129)
# Name Status NCT ID Phase Drugs
1 Outcome of Percutaneous Mechanical Thrombectomy to Treat Acute Deep Venous Thrombosis Unknown status NCT02959801 Phase 4
2 Prevention of Menstrual Migraines: Effects of Estrogen Add-back During the HFI in Patients Using Continuous Oral Contraceptives. Unknown status NCT01251263 Phase 4 Estradiol or Placebo;Estradiol or Placebo
3 Athena Pelvic Muscle Trainer - DUETS Trial Completed NCT01073878 Phase 4
4 Effectiveness of Flutamide in Treating Women With Premenstrual Dysphoric Disorder Completed NCT00611923 Phase 4 Flutamide;Placebo
5 Intuniv vs Placebo in the Treatment of Childhood Intermittent Explosive Disorder Completed NCT02048241 Phase 4 Intuniv
6 Atomoxetine, Placebo and Parent Management Training in Autism Completed NCT00844753 Phase 4 atomoxetine;Placebo
7 Ultrasound Plus Nerve Stimulator Versus Nerve Stimulator Guided Lumbar Plexus Block Completed NCT02020096 Phase 4
8 Treatment of Severe Childhood Aggression (The TOSCA Study) Completed NCT00796302 Phase 4 Methylphenidate HCl;Risperidone;Placebo
9 Evaluating the Effectiveness of Sertraline in Treating Women With Premenstrual Dysphoric Disorder Completed NCT00536198 Phase 4 Sertraline;Placebo
10 Short-Term Versus Long-Term Treatment for Severe Premenstrual Syndrome (PMS) Completed NCT00318773 Phase 4 sertraline
11 Premenstrual Symptoms Treatment Comparing Between Oral Contraceptives Containing Desogestrel and Drospirenone Completed NCT01482338 Phase 4 EE 20 microgram with desogestrel 150 mg;EE 20 microgram with drospirenone 3 mg
12 A Placebo-Controlled Study to Investigate the Onset of Action of Paroxetine in Premenstrual Dysphoria Completed NCT00516113 Phase 4 paroxetine
13 The Role of GABA and Neurosteroids in Premenstrual Dysphoric Disorder Completed NCT00678574 Phase 4 fluoxetine
14 Understanding Experimentally Induced Hot Flushes Completed NCT00455689 Phase 4 Leuprolide acetate
15 An Investigation of the Safety and Utility of Treximet in the Treatment of Menstrual Migraine Completed NCT01578941 Phase 4
16 CGRP, Estrogen, Cortisol, VIP, α-Amylase, PGE2, PGI2 and ß-Endorphin Levels in Menstrual Migraine Before and After Treximet Completed NCT01329562 Phase 4 Treximet;Placebo
17 Prospective Survey of Menstrual Migraine & Prevention With Eletriptan Completed NCT00259649 Phase 4 eletriptan
18 Chances for Success of CavatermTM Surgery as a Function of Uterus Probe Length Completed NCT01436903 Phase 4
19 Effectiveness And Safety Of Frovatriptan For The Management (Acute Treatment) Of Menstrual Migraine Completed NCT00904098 Phase 4 Frovatriptan;Usual Care
20 Continuous Oral Contraceptive Treatment in Premenstrual Dysphoric Disorder (PMDD) Completed NCT00927095 Phase 4 Continuous OC (EE/DROS);Intermittent OC (EE/DROS);placebo
21 Effect of Locally-Applied Simvastatin on Clinical Attachment Level and Alveolar Bone in Periodontal Maintenance Patients Recruiting NCT03452891 Phase 4 Simvastatin-Methylcellulose
22 Progesterone and Brain Imaging Study Recruiting NCT01954966 Phase 4 Progesterone;Placebo
23 Escitalopram for Premenstrual Syndrome (PMS) in Teens: A Pilot Study Terminated NCT00523705 Phase 4 escitalopram
24 Homeopathic Treatment of Premenstrual Syndrome Unknown status NCT02402049 Phase 3 Natrum muriaticum 30C;Lachesis 30C;Sepia 30C;Nux vomica 30C;Pulsatilla 30C;Folliculinum 30C;Placebo Natrum muriaticum;Placebo Lachesis;Placebo Sepia;Placebo Nux vomica;Placebo pulsatilla;Placebo Folliculinum
25 Dienogest Versus Luteal Phase Fluoxetine in the Management of Premenstrual Syndrome Unknown status NCT02427334 Phase 3 Dienogest;Fluoxetine;Placebo
26 Does Adding Oral Contraceptives to Fluoxetine Improve the Management of Premenstrual Syndrome? Unknown status NCT02562053 Phase 3 Fluoxetine;Combined oral contraceptives;Placebo 1;Placebo 2
27 Combined Oral Contraceptives and Fluoxetine Versus Combined Oral Contraceptives in Severe Premenstrual Syndrome Unknown status NCT02488538 Phase 3 Combined oral contraceptives;Fluoxetine;Combined oral contraceptives placebo;Fluoxetine placebo
28 GAMALINE®+HIPERICIN® for PMS Treatment and Vasomotor Symptoms Unknown status NCT01365676 Phase 3 GAMALINE® + HIPERICIN®;GAMALINE®
29 Intranasal PH80 Spray for Acute Management of the Symptoms of Premenstrual Dysphoric Disorder Unknown status NCT01217775 Phase 3 PH80;Placebo intranasal spray
30 Operations and Pelvic Muscle Training in the Management of Apical Support Loss: The OPTIMAL Trial Completed NCT00597935 Phase 3
31 The Impact of Serelys PMS on Symptoms of PMS Completed NCT03298607 Phase 3
32 Luteal Phase Administration of Paroxetine for the Treatment of PMDD Completed NCT00620581 Phase 3 Paroxetine
33 Comparison Between Oral Contraceptive Pills and Calcium Supplements in Treatment of Premenstrual Syndrome Completed NCT02089620 Phase 3 Yasmin;Placebo 1;Placebo 2
34 Dose-dependent Effects of VAC BNO 1095 on Cyclic Mastodynia and Premenstrual Syndrome Completed NCT01309113 Phase 3 VAC BNO 1095 film coated tablets
35 Study Evaluating Combination of Levonorgestrel (LNG) and Ethinyl Estradiol (EE) in Premenstrual Dysphoric Disorder Completed NCT00128934 Phase 3 levonorgestrel/ethinyl estradiol
36 Study Evaluating Levonorgestrel/Ethinyl Estradiol (LNG/EE) in PMS Completed NCT00161681 Phase 3 Levonorgestrel/Ethinyl Estradiol
37 Study Evaluating Combination of Levonorgestrel and Ethinyl Estradiol in Pre-Menstrual Dysphoric Disorder Completed NCT00195559 Phase 3 Levonorgestrel/Ethinyl Estradiol
38 Emotional Processing and Oxytocin Mechanisms in Premenstrual Dysphoric Disorder: A Pilot Study Completed NCT02508103 Phase 2, Phase 3 Oxytocin;Placebo
39 The Effect of Toremifene Treatment to the Magnetic Resonance Imaging (MRI) Findings in Premenstrual Mastalgia Completed NCT00534846 Phase 3 toremifene;placebo
40 Treximet (Sumatriptan/Naproxen Sodium), Formerly Known as TREXIMA, for Menstrual Migraine in Women With Dysmenorrhea Completed NCT00329459 Phase 3 sumatriptan succinate/naproxen sodium;placebo
41 Menstrual Migraine Treatment With TREXIMET (Formerly Known as TREXIMA) Completed NCT00329355 Phase 3 sumatriptan succinate/naproxen sodium
42 Clinical Research Study to Evaluate Selegiline in the Treatment of Borderline Personality Disorder Completed NCT01912391 Phase 3 Selegiline;Placebo (for Selegiline)
43 Diindolylmethane in Treating Patients With Abnormal Cervical Cells Completed NCT00462813 Phase 3 oral microencapsulated diindolylmethane
44 YAZ Premenstrual Dysphoric Disorder (PMDD) in China Completed NCT00824187 Phase 3 EE20/DRSP(YAZ, BAY86-5300);Placebo
45 Efficacy and Safety of 20 mg (2 Tablets of 10mg)VAC BNO 1095 FCT on Cyclic Mastodynia and PMS Terminated NCT01870687 Phase 3 20mg VAC BNO 1095 FCT;Placebo
46 Evaluation of Safety/Efficacy of Diagnostic Skin Test Panel and Desensitization Hormone Kit for Treatment of Premenstrual Syndrome (PMS) Unknown status NCT00873262 Phase 2 Skin test panel and desensitization kit;Skin test panel and solvent
47 Evaluation of Efficacy/Safety of EVE-PMS Skin Test Panel Unknown status NCT00866437 Phase 2 Skin test panel;Skin test panel
48 Antidepressant Treatment for Premenstrual Syndrome and Premenstrual Dysphoric Disorder Completed NCT00048854 Phase 1, Phase 2 Sertraline
49 a Clinical Trial to Evaluate the Efficacy and Safety of Agnucaston Tablets in the Treatment of Premenstrual Syndrome (PMS) Completed NCT00672607 Phase 2 extracts of Vitex agnus castus tablets;Placebo
50 Auriculotherapy in the Cares to the Premenstrual Syndrome Completed NCT01782040 Phase 2

Search NIH Clinical Center for Premenstrual Tension

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Cochrane evidence based reviews: premenstrual syndrome

Genetic Tests for Premenstrual Tension

Anatomical Context for Premenstrual Tension

MalaCards organs/tissues related to Premenstrual Tension:

42
Breast, Testes, Skin, Brain, Bone, Cortex, Liver

Publications for Premenstrual Tension

Articles related to Premenstrual Tension:

(show top 50) (show all 1337)
# Title Authors Year
1
Yoga positively affected depression and blood pressure in women with premenstrual syndrome in a randomized controlled clinical trial. ( 30712751 )
2019
2
The association of trace elements with premenstrual syndrome, dysmenorrhea and irritable bowel syndrome in adolescents. ( 30590227 )
2019
3
Diets enriched with whole grains reduce premenstrual syndrome scores in nurses: an open-label parallel-randomized controlled trial. ( 30761961 )
2019
4
Protein intake and the risk of premenstrual syndrome. ( 30774065 )
2019
5
Effects of a social-media-based support on premenstrual syndrome and physical activity among female university students in South Korea. ( 30829097 )
2019
6
Psychological factors and premenstrual syndrome: A Spanish case-control study. ( 30840651 )
2019
7
The Association Between Serum Magnesium and Premenstrual Syndrome: a Systematic Review and Meta-Analysis of Observational Studies. ( 30880352 )
2019
8
Altered exploratory behaviour and increased food intake in the spiny mouse before menstruation: a unique pre-clinical model for examining premenstrual syndrome. ( 30561655 )
2019
9
Premenstrual Syndrome, Inflammatory Status, and Mood States in Soccer Players. ( 30654383 )
2019
10
Diet quality in adolescents with premenstrual syndrome: A cross-sectional study. ( 30729645 )
2019
11
Associations between premenstrual syndrome and postpartum depression: A systematic literature review. ( 30452945 )
2018
12
Symptoms of premenstrual syndrome in female migraineurs with and without menstrual migraine. ( 30332985 )
2018
13
Prevalence of Premenstrual Syndrome and Changes in Blood Pressure with Menstrual Cycle Among University Students. ( 30837763 )
2018
14
Prevalence and association of premenstrual syndrome and premenstrual dysphoric disorder with academic performance among female university students. ( 28543046 )
2018
15
Hippocampal fractional amplitude of low-frequency fluctuation and functional connectivity changes in premenstrual syndrome. ( 28577332 )
2018
16
Premenstrual syndrome in university students: its correlation with their attitudes toward gender roles. ( 28617173 )
2018
17
The effect of omega 3 fatty acid supplementation on premenstrual syndrome and health-related quality of life: a randomized clinical trial. ( 28707491 )
2018
18
Premenstrual Syndrome Diagnosis: A Comparative Study between the Daily Record of Severity of Problems (DRSP) and the Premenstrual Symptoms Screening Tool (PSST). ( 29132173 )
2018
19
Premenstrual syndrome and premenstrual dysphoric disorders among Jordanian women. ( 29215138 )
2018
20
Larger volume and different functional connectivity of the amygdala in women with premenstrual syndrome. ( 29260367 )
2018
21
Premenstrual Syndrome: Evidence-based Evaluation and Treatment. ( 29298169 )
2018
22
Investigation of auditory potentials and cognitive impairment in premenstrual syndrome. ( 29305663 )
2018
23
Altered brain structure in women with premenstrual syndrome. ( 29329055 )
2018
24
Effect of swimming exercise on premenstrual syndrome. ( 29350276 )
2018
25
Effect of Melissa officinalis capsule on the mental health of female adolescents with premenstrual syndrome: a clinical trial study. ( 29369810 )
2018
26
Carbohydrate and fiber intake and the risk of premenstrual syndrome. ( 29379144 )
2018
27
Treatment of premenstrual syndrome: Appraising the effectiveness of cognitive behavioral therapy in addition to calcium supplement plus vitamin D. ( 29392847 )
2018
28
Low Proportion of Dietary Plant Protein among Athletes with Premenstrual Syndrome-Related Performance Impairment. ( 29434077 )
2018
29
High dose vitamin D supplementation can improve menstrual problems, dysmenorrhea, and premenstrual syndrome in adolescents. ( 29447494 )
2018
30
Effect of aromatherapy on coping with premenstrual syndrome: A randomized controlled trial. ( 29458934 )
2018
31
A lecithin phosphatidylserine and phosphatidic acid complex (PAS) reduces symptoms of the premenstrual syndrome (PMS): Results of a randomized, placebo-controlled, double-blind clinical trial. ( 29576358 )
2018
32
The effectiveness and safety of Iranian herbal medicines for treatment of premenstrual syndrome: A systematic review. ( 29632841 )
2018
33
Cortical and subcortical changes in patients with premenstrual syndrome. ( 29656266 )
2018
34
Premenstrual syndrome and alcohol consumption: a systematic review and meta-analysis. ( 29661913 )
2018
35
Premenstrual syndrome and sleep disturbances: Results from the Sao Paulo Epidemiologic Sleep Study. ( 29704826 )
2018
36
Premenstrual Syndrome: Existence, Knowledge, and Attitude Among Female University Students in Karachi. ( 29744256 )
2018
37
Thalamocortical dysconnectivity in premenstrual syndrome. ( 29774500 )
2018
38
Evaluation of aromatherapy with essential oils of Rosa damascena for the management of premenstrual syndrome. ( 29788545 )
2018
39
The effect of 8 weeks aerobic exercise on severity of physical symptoms of premenstrual syndrome: a clinical trial study. ( 29855308 )
2018
40
No Menstrual Cyclicity in Mood and Interpersonal Behaviour in Nine Women with Self-Reported Premenstrual Syndrome. ( 29874668 )
2018
41
Altered Brain Regional Homogeneity Following Electro-Acupuncture Stimulation at Sanyinjiao (SP6) in Women With Premenstrual Syndrome. ( 29904344 )
2018
42
Factors associated with premenstrual syndrome in Female High School Students. ( 29922693 )
2018
43
Effect of psychosocial interventions on the severity of premenstrual syndrome: a meta-analysis. ( 29962276 )
2018
44
Effect of an educational program on adolescent premenstrual syndrome: lessons from the Great East Japan Earthquake. ( 29988773 )
2018
45
Remote intervention using smartphone for rural women suffering from premenstrual syndrome: A propensity score matched analysis. ( 30024566 )
2018
46
Investigation of the effect of aromatherapy with Citrus aurantium blossom essential oil on premenstrual syndrome in university students: A clinical trial study. ( 30057033 )
2018
47
Biopsychosocial etiology of premenstrual syndrome: A narrative review. ( 30090776 )
2018
48
Acupuncture and acupressure for premenstrual syndrome. ( 30105749 )
2018
49
Relationship between premenstrual syndrome and basic personality traits: a cross-sectional study. ( 30110077 )
2018
50
Primary dysmenorrhea with and without premenstrual syndrome: variation in quality of life over menstrual phases. ( 30209721 )
2018

Variations for Premenstrual Tension

Expression for Premenstrual Tension

Search GEO for disease gene expression data for Premenstrual Tension.

Pathways for Premenstrual Tension

Pathways related to Premenstrual Tension according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.21 GNRH1 SHBG
2 9.47 CRH POMC

GO Terms for Premenstrual Tension

Cellular components related to Premenstrual Tension according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.65 AVP CAMP CRH GNRH1 HP OXT
2 extracellular region GO:0005576 9.44 AVP CAMP CRH GNRH1 HP LIPN
3 secretory granule GO:0030141 9.33 AVP OXT POMC

Biological processes related to Premenstrual Tension according to GeneCards Suite gene sharing:

(show all 16)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.96 AVP CAMP CRH LRP5 PRL
2 cell-cell signaling GO:0007267 9.8 AVP GNRH1 PGR POMC
3 regulation of blood pressure GO:0008217 9.61 LRP5 POMC REN
4 grooming behavior GO:0007625 9.55 AVP OXT
5 maternal behavior GO:0042711 9.54 AVP OXT
6 drinking behavior GO:0042756 9.48 OXT REN
7 response to prostaglandin E GO:0034695 9.46 GNRH1 OXT
8 response to organic cyclic compound GO:0014070 9.43 AVP GNRH1 OXT
9 regulation of signaling receptor activity GO:0010469 9.43 AVP GNRH1 OXT POMC PRL SERPINE1
10 hyperosmotic salinity response GO:0042538 9.4 AVP OXT
11 maternal aggressive behavior GO:0002125 9.37 AVP OXT
12 response to ethanol GO:0045471 9.33 AVP CRH GNRH1
13 response to ether GO:0045472 9.32 CRH OXT
14 parturition GO:0007567 9.22 CRH
15 ovulation cycle GO:0042698 9.21 GNRH1
16 female pregnancy GO:0007565 8.92 CRH GNRH1 OXT PRL

Molecular functions related to Premenstrual Tension according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 9.65 AVP CRH POMC REN SERPINE1
2 neuropeptide hormone activity GO:0005184 9.33 AVP CRH OXT
3 hormone activity GO:0005179 9.1 AVP CRH GNRH1 OXT POMC PRL
4 neurohypophyseal hormone activity GO:0005185 8.96 AVP OXT

Sources for Premenstrual Tension

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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