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MCID: PRM020
MIFTS: 51

Premenstrual Tension

Categories: Reproductive diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Premenstrual Tension

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MalaCards integrated aliases for Premenstrual Tension:

Name: Premenstrual Tension 12 15 73
Premenstrual Syndrome 44 63 73

Classifications:

MalaCards categories:
Anatomical: Reproductive diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:727
ICD10 33 N94.3
ICD9CM 35 625.4
MeSH 44 D011293
SNOMED-CT 68 82639001
Sources

Summaries for Premenstrual Tension

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PubMed Health : 63 About premenstrual syndrome: In the days leading up to their period, many women experience abdominal pain or a headache, are sad and irritable or feel bloated and generally uncomfortable. The medical term for this is “premenstrual syndrome” (PMS), also known as “premenstrual tension” (PMT). PMS symptoms are usually not very severe, and most women cope well with them. But in some women it is so bad that they are unable to go about their everyday lives during that time. Various treatments and measures can help to relieve PMS.

MalaCards based summary : Premenstrual Tension, also known as premenstrual syndrome, is related to anovulation and postpartum depression, and has symptoms including pelvic pain, pain and other symptoms associated with female genital organs and mittelschmerz. An important gene associated with Premenstrual Tension is GNRH1 (Gonadotropin Releasing Hormone 1), and among its related pathways/superpathways are Nongenotropic Androgen signaling and Glucocorticoid Pathway (HPA Axis), Pharmacodynamics. The drugs Flutamide and Guanfacine have been mentioned in the context of this disorder. Affiliated tissues include liver, brain and bone, and related phenotypes are homeostasis/metabolism and endocrine/exocrine gland

Wikipedia : 76 Premenstrual syndrome (PMS) refers to physical and emotional symptoms that occur in the one to two weeks... more...

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Related Diseases for Premenstrual Tension

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Diseases related to Premenstrual Tension via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 152)
# Related Disease Score Top Affiliating Genes
1 anovulation 30.1 GNRH1 PRL SHBG
2 postpartum depression 30.0 CRH OXT PRL
3 breast disease 29.7 PGR POMC PRL SHBG
4 anorexia nervosa 29.6 CRH OXT POMC PRL
5 acute adrenal insufficiency 10.3 POMC REN
6 hypoaldosteronism 10.3 POMC REN
7 perinephritis 10.3 MGAM REN
8 myofascial pain syndrome 10.3 CAMP POMC
9 gangliocytoma 10.2 CRH POMC
10 central nervous system germinoma 10.2 AVP POMC
11 tuberculous epididymitis 10.2 AVP POMC
12 mineral metabolism disease 10.2 MGAM POMC REN
13 suprasellar meningioma 10.2 PGR POMC
14 central nervous system germ cell tumor 10.2 AVP POMC
15 retroperitoneal leiomyosarcoma 10.2 PGR REN
16 adenohypophysitis 10.2 POMC PRL
17 hypogonadotropism 10.2 GNRH1 PRL
18 lung oat cell carcinoma 10.2 AVP POMC
19 bronchus cancer 10.2 AVP POMC
20 acth deficiency, isolated 10.2 CRH POMC
21 intracystic papillary adenoma 10.2 PGR PRL
22 adrenal cortical hypofunction 10.2 CRH POMC REN
23 adrenal gland disease 10.2 CRH POMC REN
24 benign essential hypertension 10.2 AVP MGAM REN
25 pituitary infarct 10.2 GNRH1 POMC PRL
26 chiasmal syndrome 10.2 GNRH1 POMC PRL
27 pituitary apoplexy 10.2 GNRH1 POMC PRL
28 adrenal adenoma 10.2 CRH POMC REN
29 empty sella syndrome 10.2 GNRH1 POMC PRL
30 inappropriate adh syndrome 10.2 AVP POMC REN
31 adrenal carcinoma 10.2 CRH POMC REN
32 aortic valve disease 1 10.2 LRP5 POMC REN
33 tsh producing pituitary tumor 10.2 GNRH1 POMC PRL
34 space motion sickness 10.2 AVP MGAM REN
35 freemartinism 10.2 GNRH1 OXT
36 adrenal rest tumor 10.2 GNRH1 POMC PRL
37 hypoadrenalism 10.2 CRH POMC SHBG
38 olfactory nerve neoplasm 10.2 AVP POMC
39 sella turcica neoplasm 10.1 PGR POMC PRL
40 tuberculum sellae meningioma 10.1 PGR POMC PRL
41 secondary hypertrophic osteoarthropathy 10.1 AVP POMC
42 endocrine organ benign neoplasm 10.1 POMC PRL REN
43 urinary system disease 10.1 AVP POMC REN
44 pituitary carcinoma 10.1 CRH POMC PRL
45 nelson syndrome 10.1 CRH POMC PRL
46 sheehan syndrome 10.1 CRH POMC PRL
47 acth-secreting pituitary adenoma 10.1 CRH POMC PRL
48 adenomyosis 10.1 GNRH1 PGR PRL
49 hypothyroidism, congenital, nongoitrous, 4 10.1 CRH POMC PRL
50 pelvic varices 10.1 GNRH1 PRL SHBG

Graphical network of the top 20 diseases related to Premenstrual Tension:



Diseases related to Premenstrual Tension
Sources

Symptoms & Phenotypes for Premenstrual Tension

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UMLS symptoms related to Premenstrual Tension:


pelvic pain, pain and other symptoms associated with female genital organs, mittelschmerz, unspecified symptom associated with female genital organs, other specified symptoms associated with female genital organs, female genital pain and other symptoms

MGI Mouse Phenotypes related to Premenstrual Tension:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.17 AVP CRH FLCN GNRH1 HP LIPN
2 endocrine/exocrine gland MP:0005379 9.97 CRH GNRH1 LRP5 OXT PGR POMC
3 immune system MP:0005387 9.96 CAMP CRH FLCN GNRH1 HP LRP5
4 integument MP:0010771 9.76 CRH GNRH1 OXT PGR PNN POMC
5 neoplasm MP:0002006 9.43 FLCN GNRH1 HP PGR POMC PRL
6 renal/urinary system MP:0005367 9.23 AVP CRH FLCN GNRH1 HP OXT
Sources

Drugs & Therapeutics for Premenstrual Tension

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PubMedHealth treatment related to Premenstrual Tension: 63

There isn’t much good research on what can help reduce PMS. So it isn’t clear how effective many of the PMS treatments are.Girls and women with PMS often try out different things to reduce their symptoms. For instance, some women with mild PMS try out relaxation techniques, acupuncture, getting more exercise, drinking less alcohol and coffee, or eating less salt. Others use herbal products and dietary supplements such as chaste tree extracts (Vitex agnus castus), St. John’s wort, calcium or pyridoxine vitamin B6).More severe PMS can be treated with a number of medications. But many of these medications haven’t been approved for the treatment of PMS, and they can have side effects:Hormone medications like the birth control pill or hormone patches affect women’s hormone levels and lead to an improvement in PMS or PMDD.Antidepressants: SSRIs (selective serotonin reuptake inhibitors) can help reduce severe psychological problems caused by PMS or PMDD.Painkillers can effectively relieve severe period pain and are usually well tolerated. There is very little research on whether they also help in PMS, though.Women who have problems with PMS-related water retention can take diuretics (water pills).If PMS causes psychological problems, cognitive behavioral therapy (CBT) is an option. But it isn’t clear whether it helps in PMS.

Drugs for Premenstrual Tension (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 88)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Flutamide Approved, Investigational Phase 4 13311-84-7 3397
2
Guanfacine Approved, Investigational Phase 4 29110-47-2 3519
3
Ropivacaine Approved Phase 4 84057-95-4 175805 71273
4
Methylphenidate Approved, Investigational Phase 4 113-45-1 4158
5
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
6
Risperidone Approved, Investigational Phase 4 106266-06-2 5073
7
Sertraline Approved Phase 4,Phase 1,Phase 2 79617-96-2 68617
8
Simvastatin Approved Phase 4 79902-63-9 54454
9 Fibrinolytic Agents Phase 4
10 Antineoplastic Agents, Hormonal Phase 4,Phase 1
11 Androgen Antagonists Phase 4
12 Hormones Phase 4,Phase 2,Phase 1
13 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 1
14 Hormone Antagonists Phase 4,Phase 2,Phase 1
15 Androgens Phase 4
16 Antihypertensive Agents Phase 4
17 Neurotransmitter Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
18 Adrenergic alpha-Agonists Phase 4
19 Adrenergic alpha-2 Receptor Agonists Phase 4
20 Adrenergic Agonists Phase 4
21 Adrenergic Agents Phase 4
22 Atomoxetine Hydrochloride Phase 4
23 Neurotransmitter Uptake Inhibitors Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
24 Psychotropic Drugs Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
25 Dopamine Agents Phase 4
26 Dopamine Antagonists Phase 4
27 Central Nervous System Depressants Phase 4,Phase 1
28 Serotonin Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
29 Serotonin Antagonists Phase 4
30 Dopamine Uptake Inhibitors Phase 4
31 Antipsychotic Agents Phase 4
32 Central Nervous System Stimulants Phase 4
33 Tranquilizing Agents Phase 4,Phase 1
34 Antidepressive Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
35 Serotonin Uptake Inhibitors Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
36 Anticholesteremic Agents Phase 4
37 Lipid Regulating Agents Phase 4
38 Hypolipidemic Agents Phase 4
39 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4
40 Antimetabolites Phase 4
41
Serotonin Investigational, Nutraceutical Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 50-67-9 5202
42
Paroxetine Approved, Investigational Phase 3 61869-08-7 43815
43 Cytochrome P-450 Enzyme Inhibitors Phase 3,Not Applicable
44 Antidepressive Agents, Second-Generation Phase 3,Not Applicable
45 Cytochrome P-450 CYP2D6 Inhibitors Phase 3,Not Applicable
46
Estradiol Approved, Investigational, Vet_approved Phase 2,Phase 1 50-28-2 5757
47 Estradiol valerate Approved, Investigational, Vet_approved Phase 2,Phase 1 979-32-8
48
Polyestradiol phosphate Approved Phase 2,Phase 1 28014-46-2
49
Ethinyl Estradiol Approved Phase 2 57-63-6 5991
50
Drospirenone Approved Phase 2 67392-87-4 68873

Interventional clinical trials:

(show top 50) (show all 56)
# Name Status NCT ID Phase Drugs
1 Outcome of Percutaneous Mechanical Thrombectomy to Treat Acute Deep Venous Thrombosis Unknown status NCT02959801 Phase 4
2 Athena Pelvic Muscle Trainer - DUETS Trial Completed NCT01073878 Phase 4
3 Effectiveness of Flutamide in Treating Women With Premenstrual Dysphoric Disorder Completed NCT00611923 Phase 4 Flutamide;Placebo
4 Intuniv vs Placebo in the Treatment of Childhood Intermittent Explosive Disorder Completed NCT02048241 Phase 4 Intuniv
5 Atomoxetine, Placebo and Parent Management Training in Autism Completed NCT00844753 Phase 4 atomoxetine;Placebo
6 Ultrasound Plus Nerve Stimulator Versus Nerve Stimulator Guided Lumbar Plexus Block Completed NCT02020096 Phase 4
7 Treatment of Severe Childhood Aggression (The TOSCA Study) Completed NCT00796302 Phase 4 Methylphenidate HCl;Risperidone;Placebo
8 Evaluating the Effectiveness of Sertraline in Treating Women With Premenstrual Dysphoric Disorder Completed NCT00536198 Phase 4 Sertraline;Placebo
9 Effect of Locally-Applied Simvastatin on Clinical Attachment Level and Alveolar Bone in Periodontal Maintenance Patients Not yet recruiting NCT03452891 Phase 4 Simvastatin-Methylcellulose
10 Operations and Pelvic Muscle Training in the Management of Apical Support Loss: The OPTIMAL Trial Completed NCT00597935 Phase 3
11 The Impact of Serelys PMS on Symptoms of PMS Completed NCT03298607 Phase 3
12 Luteal Phase Administration of Paroxetine for the Treatment of PMDD Completed NCT00620581 Phase 3 Paroxetine
13 Antidepressant Treatment for Premenstrual Syndrome and Premenstrual Dysphoric Disorder Completed NCT00048854 Phase 1, Phase 2 Sertraline
14 a Clinical Trial to Evaluate the Efficacy and Safety of Agnucaston Tablets in the Treatment of Premenstrual Syndrome (PMS) Completed NCT00672607 Phase 2 extracts of Vitex agnus castus tablets;Placebo
15 Ga-DOTATATE PET for Phosphaturic Mesenchymal Tumors in Patients With Tumor Induced Osteomalacia Recruiting NCT03736564 Phase 1, Phase 2
16 Single Session Percutaneous Mechanical Thrombectomy for the Treatment of Ilio-femoral Deep Vein Thrombosis: A Preliminary Evaluation Terminated NCT02066597 Phase 2
17 Treatment of Menstrually Related Disorders With Continuous v. Interrupted Oral Contraceptives Terminated NCT00089414 Phase 2 Ethinyl Estradiol/Drospirenone;Placebo;CDB 2914
18 Dutasteride to Treat Women With Menstrually Related Mood Disorders Completed NCT00082043 Phase 1 Dutasteride;Placebo oral capsule
19 ECoG BMI for Motor and Speech Control Recruiting NCT03698149 Phase 1
20 A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer Active, not recruiting NCT01296555 Phase 1 Fulvestrant;GDC-0032;Letrozole;Midazolam
21 Deep Transcranial Magnetic Stimulation (dTMS) for the Treatment of Premenstrual Dysphoric Disorder (PMDD) Unknown status NCT02448836 Not Applicable
22 Siblings in Foster Care Unknown status NCT01104818 Not Applicable
23 [Trial of device that is not approved or cleared by the U.S. FDA] Withheld NCT01022554
24 Psychodynamic Motivation and Training Program Completed NCT01445808 Not Applicable
25 Motor Threshold and Motor Cortex Stimulation Completed NCT02255643 Not Applicable
26 Synbiotics in Advanced HIV Infection Completed NCT03009032 Not Applicable
27 Comparison of Two Psychosocial Therapies for Treating Children With Oppositional-Defiant Disorder Completed NCT00510120 Not Applicable
28 The Extended Operations And Pelvic Muscle Training In The Management Of Apical Support Loss Study Completed NCT01166373 Not Applicable
29 Comparison of Fluoxetine, Calcium and Placebo for the Treatment of Moderate to Severe Premenstrual Syndrome (PMS) Completed NCT00965562 Not Applicable Fluoxetine;Calcium;Placebo
30 Advanced Bradycardia Device Feature Utilization and Clinical Outcomes II Completed NCT02577887
31 Adaptive Plasticity Following Rehabilitation in Multiple Sclerosis Completed NCT03608527 Not Applicable
32 Mobile Health Intervention in Increasing HPV Vaccine Coverage Among Young Adult Gay and Bisexual Men Completed NCT02835755 Not Applicable
33 Foster Teens' Risk During Transition Completed NCT02037750 Not Applicable
34 QuickOptTM Study - Using the QuickOptTM Method for Timing Cycle Optimization Completed NCT00918294 Not Applicable
35 A Comparison of Visualization Between Shamrock Technique and Paramedian Transverse Scan in Lumbar Plexus Blockade Completed NCT02982031 Not Applicable
36 Using Electrocorticogram (ECoG) in Predicting Eloquent Cortex and Post-Op Functional Outcomes in Patients With Brain Tumors Recruiting NCT02754544 Not Applicable
37 Caregiver-Guided Pain Management Training in Palliative Care Recruiting NCT02430467 Not Applicable
38 Personalize my Treatment Recruiting NCT02355171
39 Integrated Primary Care for Chronic Lung Disease: PACK Brazil Recruiting NCT02786030 Not Applicable
40 Efficacy of Pediatric Manual Therapy in the Positional Plagiocephaly Recruiting NCT03659032 Not Applicable
41 Digital Parent Training for Disruptive Behaviors in Children Recruiting NCT03697837 Not Applicable
42 Nonarthritic Hip Disease Evaluation And Treatment Recruiting NCT03519087 Not Applicable
43 Pulmonary Embolism Response to Fragmentation, Embolectomy, & Catheter Thrombolysis: PERFECT Recruiting NCT01097928
44 Investigation on the Cortical Communication (CortiCom) System Recruiting NCT03567213 Not Applicable
45 Neuromodulation for Accidental Bowel Leakage Recruiting NCT03278613 Not Applicable
46 A Prospective Study Comparing Suture Anchor and Soft Tissue Pectoralis Major Tendon Techniques for Biceps Tenodesis Recruiting NCT03529162 Not Applicable
47 Effect of Homeopathy, Acupuncture or Anthroposophic Medicine in Women's Quality of Life Recruiting NCT02504515 Not Applicable
48 Effectiveness of an Intervention in Improving Medication Adherence Among Malay Patients With Underlying Type 2 Diabetes Mellitus in Malaysia Recruiting NCT03228706 Not Applicable
49 The "Motoric Cognitive Risk" Syndrome in the Canadian Population Recruiting NCT03679026
50 Food Supplement Treatment for Wasting Children in Indonesia Active, not recruiting NCT03509155 Not Applicable

Search NIH Clinical Center for Premenstrual Tension

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: premenstrual syndrome

Sources

Genetic Tests for Premenstrual Tension

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Anatomical Context for Premenstrual Tension

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MalaCards organs/tissues related to Premenstrual Tension:

41
Liver, Brain, Bone, Pituitary, Thyroid, Heart, Ovary
Sources

Publications for Premenstrual Tension

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Articles related to Premenstrual Tension:

(show top 50) (show all 1205)
# Title Authors Year
1
Associations between premenstrual syndrome and postpartum depression: A systematic literature review. ( 30452945 )
2018
2
Symptoms of premenstrual syndrome in female migraineurs with and without menstrual migraine. ( 30332985 )
2018
3
Premenstrual Syndrome Diagnosis: A Comparative Study between the Daily Record of Severity of Problems (DRSP) and the Premenstrual Symptoms Screening Tool (PSST). ( 29132173 )
2018
4
Premenstrual syndrome and premenstrual dysphoric disorders among Jordanian women. ( 29215138 )
2018
5
Larger volume and different functional connectivity of the amygdala in women with premenstrual syndrome. ( 29260367 )
2018
6
Premenstrual Syndrome: Evidence-based Evaluation and Treatment. ( 29298169 )
2018
7
Investigation of auditory potentials and cognitive impairment in premenstrual syndrome. ( 29305663 )
2018
8
Altered brain structure in women with premenstrual syndrome. ( 29329055 )
2018
9
Effect of swimming exercise on premenstrual syndrome. ( 29350276 )
2018
10
Effect of Melissa officinalis capsule on the mental health of female adolescents with premenstrual syndrome: a clinical trial study. ( 29369810 )
2018
11
Carbohydrate and fiber intake and the risk of premenstrual syndrome. ( 29379144 )
2018
12
Treatment of premenstrual syndrome: Appraising the effectiveness of cognitive behavioral therapy in addition to calcium supplement plus vitamin D. ( 29392847 )
2018
13
Low Proportion of Dietary Plant Protein among Athletes with Premenstrual Syndrome-Related Performance Impairment. ( 29434077 )
2018
14
High dose vitamin D supplementation can improve menstrual problems, dysmenorrhea, and premenstrual syndrome in adolescents. ( 29447494 )
2018
15
Effect of aromatherapy on coping with premenstrual syndrome: A randomized controlled trial. ( 29458934 )
2018
16
A lecithin phosphatidylserine and phosphatidic acid complex (PAS) reduces symptoms of the premenstrual syndrome (PMS): Results of a randomized, placebo-controlled, double-blind clinical trial. ( 29576358 )
2018
17
The effectiveness and safety of Iranian herbal medicines for treatment of premenstrual syndrome: A systematic review. ( 29632841 )
2018
18
Cortical and subcortical changes in patients with premenstrual syndrome. ( 29656266 )
2018
19
Premenstrual syndrome and alcohol consumption: a systematic review and meta-analysis. ( 29661913 )
2018
20
Premenstrual syndrome and sleep disturbances: Results from the Sao Paulo Epidemiologic Sleep Study. ( 29704826 )
2018
21
Premenstrual Syndrome: Existence, Knowledge, and Attitude Among Female University Students in Karachi. ( 29744256 )
2018
22
Thalamocortical dysconnectivity in premenstrual syndrome. ( 29774500 )
2018
23
Evaluation of aromatherapy with essential oils of Rosa damascena for the management of premenstrual syndrome. ( 29788545 )
2018
24
The effect of 8 weeks aerobic exercise on severity of physical symptoms of premenstrual syndrome: a clinical trial study. ( 29855308 )
2018
25
No Menstrual Cyclicity in Mood and Interpersonal Behaviour in Nine Women with Self-Reported Premenstrual Syndrome. ( 29874668 )
2018
26
Altered Brain Regional Homogeneity Following Electro-Acupuncture Stimulation at Sanyinjiao (SP6) in Women With Premenstrual Syndrome. ( 29904344 )
2018
27
Factors associated with premenstrual syndrome in Female High School Students. ( 29922693 )
2018
28
Effect of psychosocial interventions on the severity of premenstrual syndrome: a meta-analysis. ( 29962276 )
2018
29
Effect of an educational program on adolescent premenstrual syndrome: lessons from the Great East Japan Earthquake. ( 29988773 )
2018
30
Remote intervention using smartphone for rural women suffering from premenstrual syndrome: A propensity score matched analysis. ( 30024566 )
2018
31
Investigation of the effect of aromatherapy with Citrus aurantium blossom essential oil on premenstrual syndrome in university students: A clinical trial study. ( 30057033 )
2018
32
Biopsychosocial etiology of premenstrual syndrome: A narrative review. ( 30090776 )
2018
33
Acupuncture and acupressure for premenstrual syndrome. ( 30105749 )
2018
34
Relationship between premenstrual syndrome and basic personality traits: a cross-sectional study. ( 30110077 )
2018
35
Primary dysmenorrhea with and without premenstrual syndrome: variation in quality of life over menstrual phases. ( 30209721 )
2018
36
Posttraumatic stress disorder and development of premenstrual syndrome in a longitudinal cohort of women. ( 30293199 )
2018
37
Cardiovascular Autonomic Profile in Women With Premenstrual Syndrome. ( 30327616 )
2018
38
Association Between Suicidal Behavior and Clinical Features of Premenstrual Syndrome and Menstrual History: A Cross Sectional Study. ( 30344818 )
2018
39
Adolescents with premenstrual syndrome: not only what you eat but also how you eat matters! ( 30352038 )
2018
40
Effects of Geranium Aromatherapy Massage on Premenstrual Syndrome: A Clinical Trial. ( 30533209 )
2018
41
Prevalence and association of premenstrual syndrome and premenstrual dysphoric disorder with academic performance among female university students. ( 28543046 )
2018
42
Hippocampal fractional amplitude of low-frequency fluctuation and functional connectivity changes in premenstrual syndrome. ( 28577332 )
2018
43
Premenstrual syndrome in university students: its correlation with their attitudes toward gender roles. ( 28617173 )
2018
44
Relationship between Anxiety and Interleukin 10 in Female Soccer Players with and Without Premenstrual Syndrome (PMS). ( 28847026 )
2017
45
Premenstrual syndrome and fibromyalgia: the frequency of the coexistence and their effects on quality of life. ( 28277106 )
2017
46
The cytokine-hormone axis - the link between premenstrual syndrome and postpartum depression. ( 28443697 )
2017
47
Stress reactivity and emotion in premenstrual syndrome. ( 28670129 )
2017
48
The effect of omega 3 fatty acid supplementation on premenstrual syndrome and health-related quality of life: a randomized clinical trial. ( 28707491 )
2017
49
Factors associated with the severity of premenstrual syndrome among Iranian college students. ( 28737241 )
2017
50
Premenstrual syndrome (PMS) among high school students. ( 28860863 )
2017
Sources

Variations for Premenstrual Tension

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Expression for Premenstrual Tension

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Search GEO for disease gene expression data for Premenstrual Tension.
Sources

Pathways for Premenstrual Tension

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Pathways related to Premenstrual Tension according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Nongenotropic Androgen signaling 1
10.21 GNRH1 SHBG
2
Glucocorticoid Pathway (HPA Axis), Pharmacodynamics 61
9.47 CRH POMC
Sources

GO Terms for Premenstrual Tension

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Cellular components related to Premenstrual Tension according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.81 AVP CAMP CRH GNRH1 HP OXT
2 extracellular region GO:0005576 9.4 AVP CAMP CRH GNRH1 HP LIPN
3 secretory granule GO:0030141 9.26 AVP OXT POMC PRL

Biological processes related to Premenstrual Tension according to GeneCards Suite gene sharing:

(show all 16)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.95 AVP CAMP CRH LRP5 PRL
2 regulation of signaling receptor activity GO:0010469 9.83 AVP GNRH1 OXT POMC PRL
3 cell-cell signaling GO:0007267 9.8 AVP GNRH1 PGR POMC
4 regulation of blood pressure GO:0008217 9.58 LRP5 POMC REN
5 grooming behavior GO:0007625 9.56 AVP OXT
6 maternal behavior GO:0042711 9.54 AVP OXT
7 parturition GO:0007567 9.52 CRH PRL
8 ovulation cycle GO:0042698 9.51 GNRH1 PRL
9 drinking behavior GO:0042756 9.48 OXT REN
10 response to prostaglandin E GO:0034695 9.46 GNRH1 OXT
11 response to organic cyclic compound GO:0014070 9.46 AVP GNRH1 OXT PRL
12 hyperosmotic salinity response GO:0042538 9.37 AVP OXT
13 maternal aggressive behavior GO:0002125 9.32 AVP OXT
14 response to ether GO:0045472 9.26 CRH OXT
15 response to ethanol GO:0045471 9.26 AVP CRH GNRH1 PRL
16 female pregnancy GO:0007565 8.92 CRH GNRH1 OXT PRL

Molecular functions related to Premenstrual Tension according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuropeptide hormone activity GO:0005184 9.33 AVP CRH OXT
2 hormone activity GO:0005179 9.1 AVP CRH GNRH1 OXT POMC PRL
3 neurohypophyseal hormone activity GO:0005185 8.96 AVP OXT
Sources

Sources for Premenstrual Tension

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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