Premenstrual Tension

Categories: Reproductive diseases

Aliases & Classifications for Premenstrual Tension

MalaCards integrated aliases for Premenstrual Tension:

Name: Premenstrual Tension 12 15 71
Premenstrual Syndrome 43 62 71


External Ids:

Disease Ontology 12 DOID:727
ICD9CM 34 625.4
MeSH 43 D011293
SNOMED-CT 67 82639001
ICD10 32 N94.3
UMLS 71 C0033046 C0376356

Summaries for Premenstrual Tension

PubMed Health : 62 About premenstrual syndrome: In the days leading up to their period, many women experience abdominal pain or a headache, are sad and irritable or feel bloated and generally uncomfortable. The medical term for this is “premenstrual syndrome” (PMS), also known as “premenstrual tension” (PMT). PMS symptoms are usually not very severe, and most women cope well with them. But in some women it is so bad that they are unable to go about their everyday lives during that time. Various treatments and measures can help to relieve PMS.

MalaCards based summary : Premenstrual Tension, also known as premenstrual syndrome, is related to sexual disorder and amenorrhea, and has symptoms including pelvic pain, pain and other symptoms associated with female genital organs and mittelschmerz. An important gene associated with Premenstrual Tension is GNRH1 (Gonadotropin Releasing Hormone 1), and among its related pathways/superpathways are Antipsychotics Pathway (Metabolic Side Effects), Pharmacodynamics and Nongenotropic Androgen signaling. The drugs Estradiol and Polyestradiol phosphate have been mentioned in the context of this disorder. Affiliated tissues include breast, skin and testes.

Wikipedia : 74 Premenstrual syndrome (PMS) refers to emotional and physical symptoms that regularly occur in the one to... more...

Related Diseases for Premenstrual Tension

Diseases related to Premenstrual Tension via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 201)
# Related Disease Score Top Affiliating Genes
1 sexual disorder 29.8 SHBG POMC GNRH1
2 amenorrhea 29.6 SHBG POMC GNRH1
3 pain agnosia 29.6 POMC LIPN
4 migraine with or without aura 1 29.6 REN POMC MTRNR2L5 LIPN
5 hyperprolactinemia 29.5 SHBG POMC GNRH1
6 hypothyroidism 29.2 SHBG REN POMC GNRH1
7 infertility 29.2 SHBG PGR GNRH1
8 breast disease 29.1 SHBG POMC PGR
9 estrogen excess 29.0 SHBG PGR GNRH1
10 ovarian disease 28.1 SHBG REN POMC PGR GNRH1
11 mood disorder 10.5
12 postpartum depression 10.3
13 hypothalamic disease 10.3 POMC GNRH1
14 bell's palsy 10.3 MTRNR2L5 LIPN
15 pituitary apoplexy 10.3 POMC GNRH1
16 facial nerve disease 10.3 MTRNR2L5 LIPN
17 empty sella syndrome 10.3 POMC GNRH1
18 facial paralysis 10.3 MTRNR2L5 LIPN
19 van maldergem syndrome 1 10.3 POMC GNRH1
20 adrenal hypoplasia, congenital 10.2 POMC GNRH1
21 diabetes insipidus, neurohypophyseal 10.2 POMC GNRH1
22 bronchiectasis 3 10.2 GNRH1 CYP3A5
23 acute adrenal insufficiency 10.2 REN POMC
24 depression 10.2
25 hypoaldosteronism 10.2 REN POMC
26 bipolar disorder 10.2
27 corticosterone methyloxidase type i deficiency 10.2 REN POMC
28 inappropriate adh syndrome 10.2 REN POMC
29 major affective disorder 8 10.2
30 major affective disorder 9 10.2
31 rickets 10.2
32 hypoglycemia 10.2
33 acth-independent macronodular adrenal hyperplasia 10.2 POMC GNRH1
34 taqi polymorphism 10.2 REN ANKK1
35 diffuse peritoneal leiomyomatosis 10.1 PGR GNRH1
36 peritoneal benign neoplasm 10.1 PGR GNRH1
37 apparent mineralocorticoid excess 10.1 REN POMC
38 polyp of corpus uteri 10.1 PGR GNRH1
39 adrenal cortical hypofunction 10.1 REN POMC
40 anxiety 10.1
41 eclampsia 10.1
42 mental depression 10.1
43 fainting 10.1
44 adenomyoma 10.1 PGR GNRH1
45 obsessive-compulsive disorder 10.1
46 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.1
47 generalized anxiety disorder 10.1
48 panic disorder 10.1
49 hyperaldosteronism, familial, type i 10.1 REN POMC
50 vaginal discharge 10.1 PGR GNRH1

Graphical network of the top 20 diseases related to Premenstrual Tension:

Diseases related to Premenstrual Tension

Symptoms & Phenotypes for Premenstrual Tension

UMLS symptoms related to Premenstrual Tension:

pelvic pain, pain and other symptoms associated with female genital organs, mittelschmerz, unspecified symptom associated with female genital organs, other specified symptoms associated with female genital organs, female genital pain and other symptoms

Drugs & Therapeutics for Premenstrual Tension

PubMed Health treatment related to Premenstrual Tension: 62

There isn’t much good research on what can help reduce PMS. So it isn’t clear how effective many of the PMS treatments are. Girls and women with PMS often try out different things to reduce their symptoms. For instance, some women with mild PMS try out relaxation techniques, acupuncture , getting more exercise , drinking less alcohol and coffee, or eating less salt. Others use herbal products and dietary supplements such as chaste tree extracts (Vitex agnus castus), St. John’s wort, calcium or pyridoxine vitamin B6 ). More severe PMS can be treated with a number of medications. But many of these medications haven’t been approved for the treatment of PMS, and they can have side effects: Hormone medications like the birth control pill or hormone patches affect women’s hormone levels and lead to an improvement in PMS or PMDD. Antidepressants : SSRIs (selective serotonin reuptake inhibitors ) can help reduce severe psychological problems caused by PMS or PMDD. Painkillers can effectively relieve severe period pain and are usually well tolerated. There is very little research on whether they also help in PMS, though. Women who have problems with PMS-related water retention can take diuretics (water pills ) . If PMS causes psychological problems, cognitive behavioral therapy (CBT) is an option. But it isn’t clear whether it helps in PMS.

Drugs for Premenstrual Tension (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 116)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
Polyestradiol phosphate Approved Phase 4 28014-46-2
Naproxen Approved, Vet_approved Phase 4 22204-53-1 1302 156391
Calcium carbonate Approved, Investigational Phase 4 471-34-1
Fluoxetine Approved, Vet_approved Phase 4 54910-89-3 3386
Sertraline Approved Phase 4 79617-96-2 68617
Desogestrel Approved Phase 4 54024-22-5 40973
Frovatriptan Approved, Investigational Phase 4 158747-02-5 77992
Leuprolide Approved, Investigational Phase 4 53714-56-0 657181 3911
Flutamide Approved, Investigational Phase 4 13311-84-7 3397
Paroxetine Approved, Investigational Phase 4 61869-08-7 43815
Salmon calcitonin Approved, Investigational Phase 4 47931-85-1 16129616
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754
Hydrocortisone acetate Approved, Vet_approved Phase 4 50-03-3
Sumatriptan Approved, Investigational Phase 4 103628-46-2 5358
Epoprostenol Approved Phase 4 35121-78-9, 61849-14-7 5282411 5280427
Dinoprostone Approved Phase 4 363-24-6 5280360
Citalopram Approved Phase 4 59729-33-8 2771
19 Tezosentan Investigational Phase 4 180384-57-0
Calcitonin gene-related peptide Investigational Phase 4 83652-28-2
21 Estradiol 17 beta-cypionate Phase 4
22 Estradiol 3-benzoate Phase 4
23 Hormones Phase 4
24 Calcium, Dietary Phase 4
25 Hormone Antagonists Phase 4
26 Estrogens Phase 4
27 Contraceptives, Oral, Combined Phase 4
28 Analgesics, Non-Narcotic Phase 4
29 Analgesics Phase 4
30 Cyclooxygenase Inhibitors Phase 4
31 Antirheumatic Agents Phase 4
32 Anti-Inflammatory Agents Phase 4
33 Anti-Inflammatory Agents, Non-Steroidal Phase 4
34 Cytochrome P-450 Enzyme Inhibitors Phase 4
35 Dacuronium Phase 4
36 Antineoplastic Agents, Hormonal Phase 4
37 Androgen Antagonists Phase 4
38 Androgens Phase 4
39 Serotonin Receptor Agonists Phase 4
40 Antacids Phase 4
41 Anti-Ulcer Agents Phase 4
42 Gastrointestinal Agents Phase 4
43 Serotonin 5-HT1 Receptor Agonists Phase 4
44 Vasoconstrictor Agents Phase 4
45 Hydrocortisone 17-butyrate 21-propionate Phase 4
46 Endorphins Phase 4
47 Hydrocortisone hemisuccinate Phase 4
48 Katacalcin Phase 4
49 calcitonin Phase 4
50 Neurotransmitter Agents Phase 4

Interventional clinical trials:

(show top 50) (show all 74)
# Name Status NCT ID Phase Drugs
1 Prevention of Menstrual Migraines: Effects of Estrogen Add-back During the HFI in Patients Using Continuous Oral Contraceptives. Unknown status NCT01251263 Phase 4 Estradiol or Placebo;Estradiol or Placebo
2 Short-Term Versus Long-Term Treatment for Severe PMS Completed NCT00318773 Phase 4 sertraline
3 A Comparative Efficacy of Low-dose Combine Oral Contraceptives Containing Desogestrel 150 mg and Drospirenone 3 mg on Premenstrual Symptoms Completed NCT01482338 Phase 4 EE 20 microgram with desogestrel 150 mg;EE 20 microgram with drospirenone 3 mg
4 The Role of GABA and Neurosteroids in Premenstrual Dysphoric Disorder Completed NCT00678574 Phase 4 fluoxetine
5 An Investigation of the Safety and Utility of Treximet in the Treatment of Menstrual Migraine Completed NCT01578941 Phase 4
6 Androgen Hormones in PMDD Completed NCT00611923 Phase 4 Flutamide;Placebo
7 A Placebo-Controlled Study to Investigate the Onset of Action of Paroxetine When Used for the Treatment of Premenstrual Dysphoria Completed NCT00516113 Phase 4 paroxetine
8 Effectiveness And Safety Of Frovatriptan For The Management (Acute Treatment)Of Menstrual Migraine Completed NCT00904098 Phase 4 Frovatriptan;Usual Care
9 Understanding Experimentally Induced Hot Flushes and Their Impact on Sleep and Mood Completed NCT00455689 Phase 4 Leuprolide acetate
10 Symptom Onset Antidepressant Treatment for PMDD Completed NCT00536198 Phase 4 Sertraline;Placebo
11 Calcium for the Prevention of Postpartum Depression Completed NCT00228033 Phase 4 Elemental calcium (as carbonate)
12 Evaluation of CGRP, Estrogen, Cortisol, VIP, α-Amylase, PGE2, PGI2 and ß-Endorphin Levels in Saliva of Menstrual Migraine Patients Before and After Treatment With Treximet™ Completed NCT01329562 Phase 4 Treximet;Placebo
13 Escitalopram for Premenstrual Syndrome (PMS) in Teens: A Pilot Study Terminated NCT00523705 Phase 4 escitalopram
14 EnBrace HR for Premenstrual Syndrome (PMS) With Prominent Mood Symptoms (or Menstrual Related Mood Disorders, MRMD) Withdrawn NCT04123483 Phase 4 EnBrace HR Softgel
15 Phase 3 Study Efficacy and Tolerance: The Use of 2 Phytomedicines in Association GAMALINE® 900mg + HIPERICIN® 300mg for the Treatment of Pre-Menstrual Syndrome (PMS) and Vasomotor Symptoms Unknown status NCT01365676 Phase 3 GAMALINE® + HIPERICIN®;GAMALINE®
16 The Synergistic Use of Combined Oral Contraceptives and Fluoxetine Versus Combined Oral Contraceptives in the Management of Severe Premenstrual Syndrome: A Randomized Double Blind Placebo Controlled Trial Unknown status NCT02488538 Phase 3 Combined oral contraceptives;Fluoxetine;Combined oral contraceptives placebo;Fluoxetine placebo
17 Dienogest Versus Luteal Phase Fluoxetine in the Management of Premenstrual Syndrome: A Randomized Double Blind Placebo Controlled Trial Unknown status NCT02427334 Phase 3 Dienogest;Fluoxetine;Placebo
18 Does Adding Combined Oral Contraceptives to Fluoxetine Improve the Management of Premenstrual Syndrome? A Double Blind Placebo Controlled Study. Unknown status NCT02562053 Phase 3 Fluoxetine;Combined oral contraceptives;Placebo 1;Placebo 2
19 Is Homeopathic Treatment a Placebo Treatment? - Homeopathic Treatment of Premenstrual Syndrome- A Prospective, Randomized, Double-blind, Placebo-controlled Clinical Trial Unknown status NCT02402049 Phase 3 Natrum muriaticum 30C;Lachesis 30C;Sepia 30C;Nux vomica 30C;Pulsatilla 30C;Folliculinum 30C;Placebo Natrum muriaticum;Placebo Lachesis;Placebo Sepia;Placebo Nux vomica;Placebo pulsatilla;Placebo Folliculinum
20 A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effect of Levonorgestrel 90 Mcg and Ethinyl Estradiol 20 Mcg in a Continuous Daily Regimen on Menstrual Cycle-Related Symptoms Completed NCT00161681 Phase 3 Levonorgestrel/Ethinyl Estradiol
21 A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of a Combination of Levonorgestrel and Ethinyl Estradiol in a Continuous Daily Regimen in Subjects With Premenstrual Dysphoric Disorder Completed NCT00128934 Phase 3 levonorgestrel/ethinyl estradiol
22 A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of a Combination of Levonorgestrel and Ethinyl Estradiol in a Continuous Daily Regimen in Subjects With Premenstrual Dysphoric Disorder Completed NCT00195559 Phase 3 Levonorgestrel/Ethinyl Estradiol
23 Calcium Supplements Versus Oral Contraceptive Pills Containing Drospirenone in Treating Mild to Moderate Premenstrual Syndrome: A Double Blind Randomized Placebo Controlled Trial Completed NCT02089620 Phase 3 Yasmin;Placebo 1;Placebo 2
24 Double-blind Comparison of VAC BNO 1095 Film Coated Tablets With Placebo to Identify Dose Dependent Effects in Patients Suffering From Cyclic Mastodynia and Premenstrual Syndrome Completed NCT01309113 Phase 3 VAC BNO 1095 film coated tablets
25 The Impact of Sérélys PMS, a Herbal Remedy Based on Pollen Extraction and Saffron, on Symptoms of PMS: A Randomized, Double-blinded, Placebo Controlled Study Completed NCT03298607 Phase 3
26 A Phase III Randomized Double-blind, 12 Week, Placebo Controlled Trial of Transdermal Selegiline in Borderline Personality Disorder (BPD) to Evaluate Efficacy and Safety Completed NCT01912391 Phase 3 Selegiline;Placebo (for Selegiline)
27 An Investigation Into the Effects of Diidolylmethane (BioResponse DIM®) Supplementation in Women With Low-Grade Cervical Cytological Abnormalities [CRISP-1] Completed NCT00462813 Phase 3 oral microencapsulated diindolylmethane
28 The Effect of Toremifene Treatment to the Magnetic Resonance Imaging Findings in Women Suffering From Premenstrual Mastalgia Completed NCT00534846 Phase 3 toremifene;placebo
29 Emotional Processing and Oxytocin Mechanisms in Premenstrual Dysphoric Disorder: A Pilot Study Completed NCT02508103 Phase 2, Phase 3 Oxytocin;Placebo
30 Prospective, Double-blind, Placebo-controlled, Parallel-group, Multi-centre Randomized Clinical Trial to Proof Efficacy and Safety of 20 mg (2 Tablets of 10 mg) VAC BNO 1095 FCT in Patients Suffering From Cyclic Mastodynia and PMS Terminated NCT01870687 Phase 3 20mg VAC BNO 1095 FCT;Placebo
31 Prospective, Controlled, Single-blinded, Longitudinal, Two-arms, Clinical Study Evaluation of Efficacy/Safety of EVE-PMS Skin-Test Panel -Detecting Sensitivity to Sex Hormones in Women With Premenstrual Syndrome Unknown status NCT00866437 Phase 2 Skin test panel;Skin test panel
32 A Phase II Randomized, Two-arms, Single-blind, Cross Controlled Study for Evaluation the Safety and Efficacy of Diagnosis and Treatment of Premenstrual Syndrome by Detecting Skin Reactions Followed by Desensitization to Sex Hormones Unknown status NCT00873262 Phase 2 Skin test panel and desensitization kit;Skin test panel and solvent
33 a Clinical Trial to Evaluate the Efficacy and Safety of Agnucaston Tablets in the Treatment of Premenstrual Syndrome (PMS) Completed NCT00672607 Phase 2 extracts of Vitex agnus castus tablets;Placebo
34 Auriculotherapy in the Cares to the Premenstrual Syndrome: Randomized Clinical Trial Completed NCT01782040 Phase 2
35 Antidepressant Treatment for Premenstrual Syndrome and Premenstrual Dysphoric Disorder Completed NCT00048854 Phase 1, Phase 2 Sertraline
36 An Observational Study on the Efficacy of Individualised Homoeopathic Treatment on Premenstrual Syndrome in Indian Females Completed NCT02467088 Phase 2
37 The Effect of Individualised Homoeopathic Treatment Using the Grant Bentley Method in Premenstrual Syndrome Completed NCT02481973 Phase 2
38 An Exploratory Phase II, Randomised, Double-blind, Placebo-controlled, Parallel-group Study Investigating the Efficacy and Safety of Sepranolone in Women With Menstrual Migraine Recruiting NCT04102995 Phase 2 Sepranolone injection low dose;Sepranolone injection high dose;Placebo injection
39 The Treatment of Menstrually-Related Mood Disorders With Extended Versus Interrupted Oral Contraceptives Terminated NCT00089414 Phase 2 Ethinyl Estradiol/Drospirenone;Placebo;CDB 2914
40 The Treatment of Menstrually-Related Mood Disorders With the Gonadotropin Releasing Hormone (GnRH) Agonist, Depot Leuprolide Acetate (Lupron) Completed NCT00001259 Phase 1 Leuprolide;Estradiol Patches;Progesterone
41 The Effects of Dutasteride on Mood, HPA Axis, and Serum Allopregnanolone Levels in Women With Menstrual-Related Mood Disorders and Controls Completed NCT00082043 Phase 1 Dutasteride;Placebo oral capsule
42 The Symptom Experience of Women With Perimenstrual Syndrome;Women's Health Related Quality of Life. Unknown status NCT00174161
43 Evaluating Treatment With Homeopathy, Acupuncture, and Anthroposophic Medicine in Improving the Quality of Life for Women Treated at the Public Unified Healthcare System Unknown status NCT02504515
44 Curcumin Supplementation for Gynecological Diseases Including Pelvic Inflammatory Disease Endometritis, Endometriosis: A Pilot Study Unknown status NCT03016039
45 Self-modulation of Prefrontal Alpha Asymmetry:Novel Neurofeedback Treatment of Affective Instability in Premenstrual Dysphoric Disorder(PMDD) Unknown status NCT01945372
46 Comparison of the Prophylactic Effect Between Acupuncture and Acupressure on Menstrual Migraine Unknown status NCT02592681
47 Effect of Zumba Dance on Premenstrual Tension:8 Weeks Randomized Controlled Trial Completed NCT03529721
48 Fibromyalgia and Psychiatric Symptoms Among PMS and PMDD Patients Completed NCT00229346
49 Effect of Sufficient Dietary Calcium Intake in Women With Premenstrual Syndrome Completed NCT02809066
50 The Oral Contraceptive Pill for Premenstrual Worsening of Depression. Completed NCT00633360 Drospirenone and ethinyl estradiol;Placebo

Search NIH Clinical Center for Premenstrual Tension

Inferred drug relations via UMLS 71 / NDF-RT 50 :

Mefenamic Acid

Cochrane evidence based reviews: premenstrual syndrome

Genetic Tests for Premenstrual Tension

Anatomical Context for Premenstrual Tension

MalaCards organs/tissues related to Premenstrual Tension:

Breast, Skin, Testes, Brain, Liver, Thyroid, Pituitary

Publications for Premenstrual Tension

Articles related to Premenstrual Tension:

(show top 50) (show all 2679)
# Title Authors PMID Year
The treatment of severe premenstrual syndrome with goserelin with and without 'add-back' estrogen therapy: a placebo-controlled study. 61 54
10368798 1999
Gonadotropin-releasing hormone agonist in the treatment of premenstrual symptoms with and without ongoing dysphoria: a controlled study. 61 54
9230648 1997
Clinical applications of GnRH and its analogues. 54 61
18407075 1992
Diet quality in adolescents with premenstrual syndrome: A cross-sectional study. 61
30729645 2020
Longitudinal assessment of symptoms of postpartum mood disorder in women with and without a history of depression. 61
31350668 2020
Exercise for premenstrual syndrome: a systematic review and meta-analysis of randomised controlled trials. 61
32522750 2020
The effects of psychoeducation based on the cognitive-behavioral approach on premenstrual syndrome symptoms: A randomized controlled trial. 61
32538501 2020
Are premenstrual syndrome and dysmenorrhea related to the personality structure of women? A descriptive relation-seeker type study. 61
32488914 2020
Effect of zinc supplementation on quality of life and sleep quality in young women with premenstrual syndrome: a randomized, double-blind, placebo-controlled trial. 61
32514756 2020
Pelvic floor dysfunctions in female cheerleaders: a cross-sectional study. 61
31414159 2020
Homeopathic Remedies in Psychiatric Disorders: A Meta-analysis of Randomized Controlled Trials. 61
32332462 2020
The role of immune and oxidative pathways in menstrual cycle associated depressive, physio-somatic, breast and anxiety symptoms: Modulation by sex hormones. 61
32526539 2020
Sleep disturbance is associated with an increased risk of menstrual problems in female Chinese university students. 61
32445135 2020
The effects of health belief model-based education and acupressure for coping with premenstrual syndrome on premenstrual symptoms and quality of life: A randomized-controlled trial. 61
32468669 2020
Relationship between a high Edinburgh Postnatal Depression Scale score and premenstrual syndrome: A prospective, observational study. 61
32416879 2020
Mood variations and personality traits in patients with epilepsy over the course of their menstrual cycle. 61
32160588 2020
Study on urinary metabolomics of premenstrual dysphoric disorder patients with liver-qi depression syndrome treated with Xiaoyaosan: Study Protocol Clinical Trial (SPIRIT Compliant). 61
32311921 2020
Dietary patterns are associated with premenstrual syndrome: evidence from a case-control study. 61
31612836 2020
Community Pharmacists' Knowledge, Attitude, and Practice in Providing Self-Care Recommendations for the Management of Premenstrual Syndrome. 61
32326630 2020
The effect of Health Belief Model-based health education programme on coping with premenstrual syndrome: a randomised controlled trial. 61
31985138 2020
Oxaloacetate reduces emotional symptoms in premenstrual syndrome (PMS): results of a placebo-controlled, cross-over clinical trial. 61
32206660 2020
The role of mental health variables and coping strategies in premenstrual syndrome. 61
31622184 2020
Cognition, The Menstrual Cycle, and Premenstrual Disorders: A Review. 61
32230889 2020
Correction of the name of author: A systematic review of the role of vitamin D and calcium in premenstrual syndrome. 61
32206663 2020
Effects of a social-media-based support on premenstrual syndrome and physical activity among female university students in South Korea. 61
30829097 2020
Effect of Zinc Supplementation on Physical and Psychological Symptoms, Biomarkers of Inflammation, Oxidative Stress, and Brain-Derived Neurotrophic Factor in Young Women with Premenstrual Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial. 61
31154571 2020
An Overview of Premenstrual Voice Syndrome: Definition, Treatment, and Future Trajectories. 61
32135006 2020
Purified and specific cytoplasmic pollen extract: a non-hormonal alternative for the treatment of menopausal symptoms. 61
32019391 2020
Association of fine-particulate and acidic-gas air pollution with premenstrual syndrome risk. 61
32186731 2020
The relationship between short stature and menstrual pattern in a large cohort of Iranian girls. 61
31339388 2020
Open-label placebo treatment of women with premenstrual syndrome: study protocol of a randomised controlled trial. 61
32071176 2020
A Pilot Randomized Treatment-Controlled Trial Comparing Vitamin B6 with Broad-Spectrum Micronutrients for Premenstrual Syndrome. 61
31928364 2020
History of premenstrual syndrome and development of postpartum depression: A systematic review and meta-analysis. 61
31783236 2020
Does Adding Fluoxetine to Combined Oral Contraceptives Containing Drospirenone Improve the Management of Severe Premenstrual Syndrome? A 6-Month Randomized Double-Blind Placebo-Controlled Three-Arm Trial. 61
32046452 2020
Menstrual Cycle Characteristics and Premenstrual Syndrome Prevalence Based on the Daily Record of Severity of Problems in Korean Young Adult Women. 61
32131079 2020
Effect of exercise on premenstrual symptoms: A systematic review. 61
31987230 2020
[Immune-inflammatory and autoimmune mechanisms in postpartum depression]. 61
32544076 2020
Paeonol at Certain Doses Alleviates Aggressive and Anxiety-Like Behaviours in Two Premenstrual Dysphoric Disorder Rat Models. 61
32351418 2020
Menstrual problems in adolescence: relationship to serum vitamins A and E, and systemic inflammation. 61
31734759 2020
Effects of Paeonia lactiflora Extract on Estrogen Receptor β, TPH2, and SERT in Rats with PMS Anxiety. 61
32219134 2020
Reduced Reward Responsiveness in Women With Moderate - to - Severe Premenstrual Syndrome: Evidence From a Probabilistic Reward Task. 61
32116845 2020
Prevalence and clinical picture of premenstrual syndrome in females from Bulgaria. 61
31969927 2020
Efficacy of Chamomile in the Treatment of Premenstrual Syndrome: A Systematic Review. 61
31970017 2019
Lifestyle Factors Associated with Premenstrual Syndrome: A Cross-sectional Study of Japanese High School Students. 61
31518647 2019
Vitex agnus-castus in premenstrual syndrome: A meta-analysis of double-blind randomised controlled trials. 61
31780016 2019
The effects of psychoeducation based on the cognitive-behavioral approach on premenstrual syndrome symptoms: A randomized controlled trial. 61
31788825 2019
The Influence of Benson Relaxation on Oxidative Stress Marker of Premenstrual Syndrome in Students of Khoy University of Medical Sciences. 61
32165968 2019
The Association Between Serum Magnesium and Premenstrual Syndrome: a Systematic Review and Meta-Analysis of Observational Studies. 61
30880352 2019
Negative Mood Is Associated with Diet and Dietary Antioxidants in University Students During the Menstrual Cycle: A Cross-Sectional Study from Guangzhou, China. 61
31888014 2019
Premenstrual syndrome is associated with altered cortisol awakening response. 61
31057066 2019

Variations for Premenstrual Tension

Expression for Premenstrual Tension

Search GEO for disease gene expression data for Premenstrual Tension.

Pathways for Premenstrual Tension

Pathways related to Premenstrual Tension according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.26 POMC ANKK1
2 9.88 SHBG GNRH1

GO Terms for Premenstrual Tension

Cellular components related to Premenstrual Tension according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.1 SHBG REN POMC MTRNR2L5 LIPN GNRH1

Biological processes related to Premenstrual Tension according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 8.8 POMC PGR GNRH1

Molecular functions related to Premenstrual Tension according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 steroid binding GO:0005496 8.62 SHBG PGR

Sources for Premenstrual Tension

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
31 HPO
32 ICD10
33 ICD10 via Orphanet
37 LifeMap
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
54 Novoseek
57 OMIM via Orphanet
61 PubMed
70 Tocris
72 UMLS via Orphanet
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