Categories: Eye diseases, Neuronal diseases

Aliases & Classifications for Presbyopia

MalaCards integrated aliases for Presbyopia:

Name: Presbyopia 12 74 43 15 62 71 32


External Ids:

Disease Ontology 12 DOID:11638
ICD9CM 34 367.4
MeSH 43 D011305
SNOMED-CT 67 41256004
ICD10 32 H52.4
UMLS 71 C0033075

Summaries for Presbyopia

PubMed Health : 62 About presbyopia: It happens to all of us eventually: You have to start holding newspapers or books further away in order to be able to read them and clearly recognize letters without straining your eyes. Seeing nearby objects less clearly is a normal part of aging. Known as presbyopia, this typically becomes noticeable in your mid-forties. Although there are no effective treatments for the causes of presbyopia, the effects can be corrected. The best and easiest way to do so is using reading glasses.

MalaCards based summary : Presbyopia is related to cycloplegia and cataract, and has symptoms including aniseikonia An important gene associated with Presbyopia is CRYAA (Crystallin Alpha A). The drugs Dipivefrin and Vitamins have been mentioned in the context of this disorder. Affiliated tissues include eye, testes and heart.

Wikipedia : 74 Presbyopia is a condition associated with the aging of the eye that results in progressively worsening... more...

Related Diseases for Presbyopia

Diseases related to Presbyopia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 71)
# Related Disease Score Top Affiliating Genes
1 cycloplegia 31.4 NBL1 IFITM2 GREM2 DPT CTSC
2 cataract 30.9 MIP CRYGS CRYAA BFSP2 BFSP1
3 corneal ectasia 30.9 TRARG1 IFITM2
4 irregular astigmatism 30.7 TRARG1 IFITM2
5 exotropia 30.4 DPT CRYAA
6 esotropia 30.3 IRGC DPT CRYAA
7 astigmatism 30.1 TRARG1 NBL1 IFITM2 GREM2 DPT CRYAA
8 senile cataract 30.0 LAMA3 CRYGS CRYAA BFSP1
9 anisometropia 29.2 TRARG1 NBL1 IFITM2 GREM2 DPT CTSC
10 refractive error 11.9
11 farsightedness 11.8
12 joint laxity, short stature, and myopia 10.8
13 myopia 10.8
14 eye disease 10.4
15 ocular motor apraxia 10.4
16 disuse amblyopia 10.4 CRYGS CRYAA
17 cataract 44 10.3 MIP CRYAA
18 regular astigmatism 10.3 TRARG1 DPT
19 cataract 31, multiple types 10.3 CRYAA BFSP1
20 phacogenic glaucoma 10.2 LAMA3 CRYAA
21 strabismus 10.2
22 aging 10.2
23 mechanical strabismus 10.2
24 early-onset sutural cataract 10.2 MIP CRYGS BFSP2
25 retinal perforation 10.2 IFITM2 CRYGS CRYAA
26 morgagni cataract 10.2 LAMA3 CRYGS CRYAA
27 early-onset nuclear cataract 10.2 MIP CRYAA BFSP1
28 galactosemia ii 10.2 CRYGS CRYAA BFSP2
29 vitreous detachment 10.2 LAMA3 DPT
30 axenfeld-rieger syndrome, type 3 10.2 CRYGS CRYAA BFSP2
31 blood group, globoside system 10.2 LAMA3 CRYAA
32 diabetic cataract 10.2 CRYGS CRYAA
33 lens subluxation 10.2 LAMA3 CRYAA BFSP1
34 glaucoma, primary open angle 10.1
35 laryngoonychocutaneous syndrome 10.1
36 yemenite deaf-blind hypopigmentation syndrome 10.1
37 myopia 6 10.1
38 microvascular complications of diabetes 5 10.1
39 monocular esotropia 10.1
40 open-angle glaucoma 10.1
41 alternating exotropia 10.1
42 ocular hypertension 10.1
43 early-onset lamellar cataract 10.1 MIP CRYGS CRYAA BFSP2
44 mature cataract 10.1 MIP LAMA3 CRYGS CRYAA
45 paraphilia disorder 10.0 RFX6 IRGC
46 posterior polar cataract 10.0 CRYGS CRYAA BFSP2 BFSP1
47 corneal dystrophy, fuchs endothelial, 1 10.0
48 ocular dominance 10.0
49 polykaryocytosis inducer 10.0
50 retinal detachment 10.0

Graphical network of the top 20 diseases related to Presbyopia:

Diseases related to Presbyopia

Symptoms & Phenotypes for Presbyopia

UMLS symptoms related to Presbyopia:


Drugs & Therapeutics for Presbyopia

PubMed Health treatment related to Presbyopia: 62

Although there are no effective treatments to fight the cause of presbyopia , the effects of presbyopia are easily corrected. The easiest way to solve the problem of not being able to see nearby objects is wearing ready-made reading glasses available in shops. But these readily available reading glasses don't account for possible differences in vision between your eyes or other features, such as astigmatism (an irregularly shaped cornea ). Individually adjusted prescription reading glasses are only available from an optician's, where glasses with the required lens power are made especially based on the results of an eye test. The distance between the pupils of your eyes and other factors are also taken into account. Reading glasses are often narrow enough for you to be able to look over them if you want to see things that are further away. If you already wore prescription glasses before presbyopia started becoming an issue, multifocals are an option. Bifocal glasses (bifocals) are one type of multifocal glasses. They have two zones divided in the middle by a visible horizontal line. The lower half of the glasses is for looking at nearby objects, and the upper half is for looking at objects that are further away. Trifocals have a visibly separate third zone for seeing objects at intermediate distances too. In varifocals (also known as progressive lenses ), the lines dividing the different zones have been smoothly polished so you can’t see them. They are the most common kind of glasses.

Drugs for Presbyopia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 35)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Dipivefrin Approved Phase 4 52365-63-6 3105
2 Vitamins Phase 4
3 Omega 3 Fatty Acid Phase 4
4 Alkylating Agents Phase 4
5 Anti-Bacterial Agents Phase 4
6 Mitomycins Phase 4
7 Antibiotics, Antitubercular Phase 4
8 Ophthalmic Solutions Phase 3
9 Pharmaceutical Solutions Phase 3
Tropicamide Approved, Investigational Phase 2 1508-75-4 5593
Choline Approved, Nutraceutical Phase 2 62-49-7 305
12 Alpha-lipoic Acid Phase 2
13 Hypolipidemic Agents Phase 2
14 Thioctic Acid Phase 2
15 Lipid Regulating Agents Phase 2
16 Gastrointestinal Agents Phase 2
17 Antimetabolites Phase 2
Hydrogen peroxide Approved, Vet_approved 7722-84-1 784
Hyaluronic acid Approved, Vet_approved 9004-61-9 53477741
Pilocarpine Approved, Investigational Early Phase 1 54-71-7, 92-13-7 5910
Meclocycline Investigational 2013-58-3 5480760
22 Contact Lens Solutions
23 Anti-Infective Agents, Local
24 Disinfectants
25 Anti-Infective Agents
26 Anesthetics
27 Tea
28 Neurotransmitter Agents Early Phase 1
29 Cholinergic Agents Early Phase 1
30 Muscarinic Agonists Early Phase 1
31 Adrenergic Agents Early Phase 1
32 Adrenergic Agonists Early Phase 1
33 Adrenergic alpha-Agonists Early Phase 1
34 Antihypertensive Agents Early Phase 1
35 Brimonidine Tartrate Early Phase 1 70359-46-5

Interventional clinical trials:

(show top 50) (show all 193)
# Name Status NCT ID Phase Drugs
1 A Prospective Safety and Effectiveness Study of a New High Repetition Rate Excimer Laser Using LASIK for the Correction of Ammetropia and Presbyopia Unknown status NCT02112968 Phase 4
2 A Prospective Safety and Effectiveness Study of the 500 Hz Technolas Perfect Vision Excimer Laser in Asian Eyes Using LASIK Unknown status NCT01977807 Phase 4
3 PHASE IV STUDY # 1162. Prospective Investigation of SUPRACOR Visual Outcomes of Presbyopic Hyperopic Patients With and Without Astigmatism Unknown status NCT01628146 Phase 4
4 A Randomized, Subject-masked Comparison of Visual Function After Bilateral Implantation of Presbyopia-correcting IOLs Completed NCT00963560 Phase 4
5 A Randomized, Subject-masked Comparison of Visual Function After Bilateral Implantation of Presbyopia-correcting IOLs Completed NCT01166971 Phase 4
6 Comparative Study of Photopic and Mesopic Distance, Intermediate and Near Visual Acuity, and Spectacle Independence With Bilateral Implantation of the Tecnis Multifocal (TMF) Intraocular Lens or Crystalens AO (CAO) Intraocular Lens Completed NCT01275118 Phase 4
7 A Prospective Study to Evaluate the Safety and Effectiveness of the Supracor Presbyopic Treatment Algorithm for Pseudophakic Eyes Using Lasik Completed NCT01387360 Phase 4
8 Evaluation of the Tecnis™ Multifocal and Crystalens™ Accommodating Intraocular Lenses Completed NCT01061281 Phase 4
9 Clinical Evaluation of the Biofinity Multifocal Lens Compared With the Air Optix Aqua Multifocal Lens and With PureVision Multifocal Lens (INNOVATION PRESBYOPIA Study) Completed NCT01591499 Phase 4
10 Visual Performance After Implantation of an Aspheric Multifocal Diffractive Intraocular Lens Completed NCT01065064 Phase 4
11 Clinical Investigation of the Vision-R800 Device. Understanding the Value of High Precision Refractions and Lenses to Optometrists and Patients. Phase 2 Recruiting NCT04208750 Phase 4
12 A Prospective Study to Evaluate the Raindrop Near Vision Inlay in Presbyopes Implanted Under a Corneal Flap or Within a Small-Incision Pocket Recruiting NCT03376412 Phase 4
13 A Prospective Study to Evaluate the Raindrop Near Vision Inlay in Presbyopes Treated With Mitomycin C During Surgery and Extended Steroid After Surgery Recruiting NCT03242317 Phase 4 Mitomycin C
14 A Prospective Study to Evaluate the Raindrop Near Vision Inlay in Presbyopic Patients With Treatments to Optimize the Ocular Surface Before Implantation Recruiting NCT03126877 Phase 4 Mitomycin C
15 A Prospective Study to Evaluate the Raindrop Near Vision Inlay in Presbyopes Implanted in Corneal Pockets With a Delayed or Non-Delayed Approach Suspended NCT03326869 Phase 4
16 A Prospective Study To Evaluate The Raindrop Near Vision Inlay In Presybopic or Pseudophakic Patients Treated With Mitomycin C Following Femtosecond Flap Creation. Terminated NCT03101501 Phase 4 Mitomycin c
17 Evaluation of the Safety & Efficacy of the LaserACE® Procedure to Restore Visual Function and Range of Accommodation Unknown status NCT01491360 Phase 3
18 A Prospective, Multicenter Clinical Trial to Evaluate the Safety and Effectiveness of the ReVision Optics, Inc., RAINDROP® NEAR VISION INLAY for the Improvement of Near and Intermediate Vision in Pseudophakic Subjects Unknown status NCT02668523 Phase 3
19 A Prospective Study To Evaluate The Safety And Effectiveness Of The SUPRACOR Presbyopic Treatment Algorithm For Myopia And Myopic Astigmatism Using LASIK Unknown status NCT01404884 Phase 3
20 Prospective, Non-randomized, Unmasked, Multicenter Clinical Investigation of the Presbia Flexivue Microlens™ for the Improvement of Near Vision in Emmetropic Presbyopes Unknown status NCT02110472 Phase 3
21 Intrastromal Correction of Ametropia by a Femtosecond Laser Unknown status NCT00928122 Phase 3
22 A Prospective Multicenter, Study to Evaluate the Safety and Effectiveness of the Presbyopia Algorithm for Hyperopia and Hyperopic Astigmatism Using LASIK Completed NCT00910403 Phase 3
23 Phase 3, Multicenter, Double-Masked, Randomized, Vehicle-Controlled, Parallel-Group Study Evaluating the Safety and Efficacy of AGN-190584 in Participants With Presbyopia Completed NCT03804268 Phase 3 AGN-190584;Vehicle
24 Intrastromal Presbyopia Correction by Means of a Femtosecond Laser Completed NCT01025050 Phase 3
25 A Prospective Study to Evaluate the Safety and Effectiveness of the Presbyopic LASIK Algorithm Completed NCT01322919 Phase 3
26 A Phase 3, Multicenter, Double-Masked, Randomized, Vehicle-Controlled, Parallel-Group Study Evaluating the Safety and Efficacy of AGN-190584 in Participants With Presbyopia Recruiting NCT03857542 Phase 3 AGN-190584
27 Clinical Evaluation of the Lenstec SBL-3 Multifocal Intraocular Lens Active, not recruiting NCT02487160 Phase 3
28 Randomized Clinical Trial of Bifocal Lenses Versus Computer-specific Progressive Addition Lenses on Symptoms and Performance on a Computer Terminated NCT00585026 Phase 3
29 A Single-Center, Double-Masked Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to Moderate Presbyopia Completed NCT03201562 Phase 2 PRX-100;PRX-100 Component #1;PRX-100 Vehicle
30 Safety and Efficacy of AGN-199201 and AGN-190584 in Patients With Presbyopia Completed NCT02197806 Phase 2 AGN-199201;AGN-190584;AGN-199201 Vehicle
31 A Single-Center, Double-Masked Evaluation of the Efficacy and Safety of PRX-100 (Aceclidine/Tropicamide) Ophthalmic Topical Formulation in the Treatment of Early to Moderate Presbyopia Completed NCT02554396 Phase 2 PRX-100;Placebo
32 A Phase 2, Multicenter, Double-masked, Randomized, Vehicle-Controlled, Study of the Concurrent Use of AGN-190584 and AGN-199201 in Patients With Presbyopia Completed NCT02595528 Phase 2 AGN-199201 ophthalmic solution;AGN-190584 ophthalmic solution;AGN-190584 vehicle;AGN-199201 + AGN-190584 Combination;AGN-199201 vehicle
33 A Phase 2, Multicenter, Double-Masked, Randomized, Vehicle-Controlled, Parallel-Group Study Evaluating the Safety, Efficacy, and Pharmacokinetics of the Fixed Combination of AGN-199201 and AGN-190584 in Patients With Presbyopia Completed NCT02780115 Phase 2 AGN-199201 ophthalmic solution;AGN-190584 ophthalmic solution;AGN-199201 Vehicle;AGN-190584 Vehicle
34 A 3-month, Randomized, Placebo-controlled, Double-masked, Multi-center Study to Evaluate the Safety and Efficacy of Topical Ocular UNR844-Cl in Subjects With Presbyopia Completed NCT03809611 Phase 2 UNR844-Cl;Placebo
35 A Phase 2a, Double-blind, Randomized, Placebo-controlled, Repeated Administration, Crossover Study to Establish Safety, Tolerability and Efficacy of PresbiDrops (CSF-1) in Presbyopic Subjects Completed NCT02745223 Phase 2 PresbiDrops (CSF-1);Placebo
36 A Phase 2a, Double-Masked, Randomized, Placebo-Controlled, Single-Administration Study to Establish Safety, Tolerability and Efficacy of PresbiDrops (CSF-1) in Presbyopic Subjects Completed NCT02965664 Phase 2 PresbiDrops (CSF-1);Placebo
37 A Phase 1/2 Prospective, Randomized, Double-Masked, Placebo-Controlled, Multicenter Study to Evaluate the Safety and Efficacy of EV06 Ophthalmic Solution, in Improving Distance Corrected Near Vision in Subjects With Presbyopia Completed NCT02516306 Phase 1, Phase 2 EV06 Ophthalmic Solution;Placebo Ophthalmic Solution
38 A Multi-Center, Double-Masked Evaluation of the Efficacy and Safety of CSF-1 in the Treatment of Presbyopia Completed NCT03885011 Phase 2 CSF-1;CSF-1 Component #1;CSF-1 Component #2
39 A First-in-Human, Phase 1/2, Dose-ascending, Multicenter, Masked, Randomized, Vehicle-controlled Study Evaluating the Safety, Tolerability, and Pharmacokinetics of AGN-241622 in Healthy Participants and Participants With Presbyopia (Stage 1 and Stage 2) and Efficacy in Participants With Presbyopia (Stage 2) Not yet recruiting NCT04403763 Phase 1, Phase 2 AGN-241622;AGN-190584;Vehicle
40 Functional and Physiological Changes Induced by Pinhole Glasses in Presbyopia Unknown status NCT02722291
41 Presbyopia Compensation: Looking for Electrophysiological Predictors Unknown status NCT02444130
42 Clinical Performance Evaluation of a Progressive Addition Lens Among Presbyopic Patients Unknown status NCT01443585
43 The Effect of Cataract Extraction on the Contractility of Ciliary Muscle Unknown status NCT00624039
44 Visual Function, Non-dependence on Glasses and Global Economic Cost in Patients Undergoing Lens Surgery With ReSTOR® Multifocal Aspheric Iol Implants Unknown status NCT01088282
45 Retrospective Functional Assessment of Activities of Daily Living (ADL) in Patients Who Underwent Bilateral Implantation of Aspheric Bifocal Intraocular Lenses or Aspheric Trifocal Intraocular Lenses Unknown status NCT03021512
46 Retrospective Functional Assessment of Activities of Daily Living (ADL) in Patients Who Underwent Mini-monovision Correction With Bilateral Implantation of Aspheric Monofocal Intraocular Lenses Unknown status NCT02431156
47 Study to Evaluate the Safety and Efficacy of HI-BRITE Large Diameter Rigid Gas Permeable Contact Lens (Hexafocon b) Test When Worn on a Daily Wear Basis in the Correction of Myopia/Hyperopia/Astigmatism/Presbyopia/ and Irregular Cornea. Unknown status NCT02812316
48 Prospective Clinical Trial of Unilateral or Bilateral Implantation of the Enlarged Depth-of-focus Intraocular Lens in Cataract Patients With Presbyopia Unknown status NCT03501654
49 Mix and Match Study of Two Multifocal Intraocular Lens With Different Add Power Unknown status NCT02556944
50 A 180 Day, Multicenter Study to Evaluate the Clinical Performance of SynergEyes A2 Hybrid Contact Lenses for Daily Wear Use in the Correction of Refractive Error With or Without Astigmatism in Non-diseased Eyes Unknown status NCT01058629

Search NIH Clinical Center for Presbyopia

Cochrane evidence based reviews: presbyopia

Genetic Tests for Presbyopia

Anatomical Context for Presbyopia

MalaCards organs/tissues related to Presbyopia:

Eye, Testes, Heart, Breast, Thymus, Brain, Cortex

Publications for Presbyopia

Articles related to Presbyopia:

(show top 50) (show all 1333)
# Title Authors PMID Year
The Influence of Type 1 Diabetes Mellitus on Amplitude of Accommodation. 61
32045272 2020
Presbyopia Correction Using Multifocal Soft Contact Lenses in Patients With Monofocal Intraocular Lenses. 61
31517737 2020
Multicenter visual outcomes comparison of 2 trifocal presbyopia-correcting intraocular lenses: 6-month postoperative results. 61
32541365 2020
Prevention and Management of Refractive Prediction Errors Following Cataract Surgery. 61
32541369 2020
Intracorneal ring segments followed by toric pseudoaccomodating IOL for treatment of patients with corneal ectasia and cataract. 61
32368687 2020
Implantation of Presbyopia-Correcting Intraocular Lenses Staged After Descemet Membrane Endothelial Keratoplasty in Patients With Fuchs Dystrophy. 61
31842037 2020
Cataract surgery in Kinshasa - Is there a place for "Monovision"? 61
32562301 2020
A Review of Pharmacological Presbyopia Treatment. 61
32511122 2020
Prevalence and causes of vision loss in East Asia in 2015: magnitude, temporal trends and projections. 61
31462416 2020
Visual and Refractive Outcomes Following Laser Blended Vision Using Non-linear Aspheric Micro-monovision. 61
32396641 2020
Unmet need for presbyopia correction and its associated factors among school teachers in Hawassa city, South Ethiopia. 61
32381065 2020
Extended Depth-of-Field Intraocular Lenses: An Update. 61
32511121 2020
Proposal of a new diffractive corneal inlay to improve near vision in a presbyopic eye. 61
32400623 2020
A 3-year follow-up study of a new corneal inlay: clinical results and outcomes. 61
31446390 2020
Ocular Drug Delivery Systems Using Contact Lenses. 61
32456518 2020
Novel harmala-ocudelic tuning (HOT) for ocular disorders. 61
32498006 2020
Clinical outcomes of cataract surgery with implantation of a continuous transitional focus intraocular lens. 61
32271523 2020
Phakic intraocular lenses: Recent advances and innovations. 61
32156485 2020
Visual outcome and optical quality after implantation of zonal refractive multifocal and extended-range-of-vision IOLs: a prospective comparison. 61
32213781 2020
Reversible Photoalignment of Liquid Crystals: a Path toward the Creation of Rewritable Lenses. 61
32238863 2020
Presbyopia and the aging eye: Existing refractive approaches and their potential impact on dry eye signs and symptoms. 61
31445772 2020
Author Correction: Suppression of presbyopia progression with pirenoxine eye drops: experiments on rats and non-blinded, randomized clinical trial of efficacy. 61
32296100 2020
Glycation-mediated inter-protein cross-linking is promoted by chaperone-client complexes of α-crystallin: Implications for lens aging and presbyopia. 61
32184356 2020
Innovative Trifocal (Quadrifocal) Presbyopia-Correcting IOLs: 1-Year Outcomes From an International Multicenter Study. 61
32358415 2020
Thirty Year Projected Magnitude (to 2050) of Near and Distance Vision Impairment and the Economic Impact if Existing Solutions are Implemented Globally. 61
31810404 2020
Age-Related Changes to the Three-Dimensional Full Shape of the Isolated Human Crystalline Lens. 61
32293664 2020
Prevalence and causes of vision loss in sub-Saharan Africa in 2015: magnitude, temporal trends and projections. 61
32229517 2020
Stromal keratophakia: Corneal inlay implantation. 61
31493488 2020
Prescription AR: a fully-customized prescription-embedded augmented reality display. 61
32225876 2020
Patients' attitudes and beliefs to presbyopia and its correction. 61
32241701 2020
[Presbyopia Correction with Intraocular Lenses]. 61
31745941 2020
Long-term Outcomes After LASIK Using a Hybrid Bi-aspheric Micro-monovision Ablation Profile for Presbyopia Correction. 61
32032429 2020
Normative patterns and factors associated with presbyopia progression in a multiethnic Asian population: the Singapore Epidemiology of Eye Diseases Study. 61
32051134 2020
Visual Function after Implantation of a Presbyopia-Correcting Trifocal Intraocular Lens. 61
31390634 2020
Model of the light sword intraocular lens: in-vitro comparative studies. 61
32010498 2020
Spectacle Independence in Patients with Prior Radial Keratotomy Following Cataract Surgery: A Case Series. 61
32110119 2020
"Pattern of ocular morbidities among pilgrims attending religious mega festive event-'Kumbh Mela 2019' at Prayagraj, India". 61
32110615 2020
Posterior chamber phakic intraocular lens for the correction of presbyopia in highly myopic patients. 61
32050231 2020
Bifocal and Multifocal Contact Lenses for Presbyopia and Myopia Control. 61
32318285 2020
How much astigmatism to treat in cataract surgery. 61
31770161 2020
One year results of presbyLASIK using hybrid bi-aspheric micro-monovision ablation profile in correction of presbyopia and myopic astigmatism. 61
32090037 2020
Review of the application of the open-source software CilOCT for semi-automatic segmentation and analysis of the ciliary muscle in OCT images. 61
32516331 2020
The use of telemedicine to support Brazilian primary care physicians in managing eye conditions: The TeleOftalmo Project. 61
32240268 2020
Correction of presbyopia: old problems with old (and new) solutions. 61
31734940 2020
Canadian Opinions on Refractive Surgery and Approaches to Presbyopia Correction. 61
32510021 2020
Can Tinted Lenses Be Used to Manipulate Pupil Size and Visual Performance When Wearing Multifocal Contact Lenses? 61
32184694 2020
The Effect of Ocular Demodex Colonization on Schirmer test and OSDI Scores in Newly Diagnosed Dry Eye Patients. 61
31393313 2020
Pharmacological Strategies for Presbyopia Correction. 61
31830297 2019
Ambient assisted living technologies for older adults with cognitive and physical impairments: a review. 61
31841201 2019
Laser asymmetric ablation method to improve corneal shape. 61
30903527 2019

Variations for Presbyopia

Expression for Presbyopia

Search GEO for disease gene expression data for Presbyopia.

Pathways for Presbyopia

GO Terms for Presbyopia

Biological processes related to Presbyopia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 animal organ morphogenesis GO:0009887 9.54 NBL1 LAMA3 GREM2
2 visual perception GO:0007601 9.46 MIP CRYGS CRYAA BFSP2
3 cell maturation GO:0048469 9.4 BFSP2 BFSP1
4 intermediate filament organization GO:0045109 9.32 BFSP2 BFSP1
5 lens fiber cell development GO:0070307 9.26 BFSP2 BFSP1
6 determination of dorsal identity GO:0048263 8.96 NBL1 GREM2
7 sequestering of BMP from receptor via BMP binding GO:0038098 8.62 NBL1 GREM2

Molecular functions related to Presbyopia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural molecule activity GO:0005198 9.33 LAMA3 CRYAA BFSP2
2 receptor ligand activity GO:0048018 9.26 NBL1 GREM2
3 structural constituent of eye lens GO:0005212 9.02 MIP CRYGS CRYAA BFSP2 BFSP1
4 BMP binding GO:0036122 8.96 NBL1 GREM2

Sources for Presbyopia

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
31 HPO
32 ICD10
33 ICD10 via Orphanet
37 LifeMap
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
54 Novoseek
57 OMIM via Orphanet
61 PubMed
70 Tocris
72 UMLS via Orphanet
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