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MCID: PRM024
MIFTS: 39

Primary Angle-Closure Glaucoma

Categories: Eye diseases
Genes Tissues Related diseases Publications Drugs
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Aliases & Classifications for Primary Angle-Closure Glaucoma

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MalaCards integrated aliases for Primary Angle-Closure Glaucoma:

Name: Primary Angle-Closure Glaucoma 12 55 15 73
Primary Angle Closure Glaucoma 12
Angle Closure Glaucoma 73

Classifications:

MalaCards categories:
Anatomical: Eye diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:1405
ICD10 33 H40.2 H40.20
ICD9CM 35 365.2 365.20
SNOMED-CT 68 42456004
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Summaries for Primary Angle-Closure Glaucoma

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MalaCards based summary : Primary Angle-Closure Glaucoma, also known as primary angle closure glaucoma, is related to open-angle glaucoma and glaucoma, primary open angle. An important gene associated with Primary Angle-Closure Glaucoma is MYOC (Myocilin). The drugs Topiramate and Pilocarpine have been mentioned in the context of this disorder. Affiliated tissues include eye, testes and retina, and related phenotypes are nervous system and no phenotypic analysis

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Related Diseases for Primary Angle-Closure Glaucoma

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Diseases related to Primary Angle-Closure Glaucoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 48)
# Related Disease Score Top Affiliating Genes
1 open-angle glaucoma 31.3 CYP1B1 MYOC OPTN
2 glaucoma, primary open angle 31.3 CYP1B1 MYOC OPTN
3 optic nerve disease 30.6 MFRP MYOC OPTN
4 ocular hypertension 30.1 MYOC OPTN
5 lens subluxation 30.0 MTHFR VSX2
6 cataract 10.8
7 neuropathy 10.3
8 retinitis pigmentosa 10.2
9 leber congenital amaurosis 4 10.2
10 retinitis 10.2
11 early-onset glaucoma 10.2 CYP1B1 MYOC
12 corneal ulcer 10.2 CYP1B1 MMP9
13 mycetoma 10.2 CYP1B1 MMP9
14 acute closed-angle glaucoma 10.2 MFRP OPTN
15 vitreous syneresis 10.2 COL11A1 OPTN
16 acrofrontofacionasal dysostosis 10.2 CYP1B1 OPTN
17 hydrophthalmos 10.1 CYP1B1 OPTN
18 low tension glaucoma 10.1 MYOC OPTN
19 amaurosis fugax 10.1 MMP9 MTHFR
20 esotropia 10.1 COL11A1 OPTN
21 anxiety 10.1
22 retinal vein occlusion 10.1
23 cornea plana 10.1
24 entropion 10.1
25 rubeosis iridis 10.1
26 fundus dystrophy 10.1
27 refractive error 10.1
28 depression 10.1
29 headache 10.1
30 axenfeld-rieger syndrome 10.1 CYP1B1 OPTN
31 glaucoma 1, open angle, a 10.1 CYP1B1 MYOC OPTN
32 excessive tearing 10.1 CYP1B1 MYOC OPTN
33 corneal edema 10.1 CYP1B1 MYOC OPTN
34 primary congenital glaucoma 10.1 CYP1B1 MYOC OPTN
35 pulmonary artery disease 10.1 MFRP MTHFR
36 juvenile glaucoma 10.1 CYP1B1 MYOC OPTN
37 glaucoma 3, primary congenital, a 10.1 CYP1B1 MYOC OPTN
38 amblyopia 10.1 MFRP OPTN
39 nervous system disease 10.0 MFRP MMP9 OPTN
40 myopia 10.0 COL11A1 MFRP MYOC
41 aniridia 1 10.0 CYP1B1 OPTN
42 microphthalmia, isolated 6 10.0 MFRP VSX2
43 mastoiditis 10.0 KERA MTHFR
44 adamantinoma of long bones 10.0 CYP1B1 MMP9 MYOC OPTN
45 microphthalmia, isolated 1 10.0 MFRP VSX2
46 ewing sarcoma 9.9 MFRP MMP9 MYOC OPTN
47 carotid stenosis 9.9 MMP9 MTHFR
48 coloboma of macula 9.8 CYP1B1 MFRP OPTN VSX2

Comorbidity relations with Primary Angle-Closure Glaucoma via Phenotypic Disease Network (PDN):


Hypertension, Essential

Graphical network of the top 20 diseases related to Primary Angle-Closure Glaucoma:



Diseases related to Primary Angle-Closure Glaucoma
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Symptoms & Phenotypes for Primary Angle-Closure Glaucoma

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MGI Mouse Phenotypes related to Primary Angle-Closure Glaucoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.76 COL11A1 MFRP MMP9 MTHFR PARL TXNRD2
2 no phenotypic analysis MP:0003012 9.43 MTHFR MYOC OPTN PARL TXNRD2 VSX2
3 vision/eye MP:0005391 9.23 CYP1B1 KERA MFRP MMP9 MTHFR MYOC
Sources

Drugs & Therapeutics for Primary Angle-Closure Glaucoma

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Drugs for Primary Angle-Closure Glaucoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 95)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Topiramate Approved Phase 4 97240-79-4 5284627
2
Pilocarpine Approved, Investigational Phase 4,Not Applicable 54-71-7, 92-13-7 5910
3
Travoprost Approved Phase 4,Phase 3 157283-68-6 5282226
4
Latanoprost Approved, Investigational Phase 4,Phase 3,Not Applicable 130209-82-4 5311221 5282380
5
Brinzolamide Approved Phase 4,Phase 3 138890-62-7 68844
6
Timolol Approved Phase 4,Phase 3 26839-75-8 33624 5478
7
Maleic acid Experimental Phase 4 110-16-7 444266
8 Neuroprotective Agents Phase 4,Phase 2
9 Anti-Obesity Agents Phase 4
10 Anticonvulsants Phase 4,Not Applicable
11 Protective Agents Phase 4,Phase 2,Not Applicable
12 Autonomic Agents Phase 4,Phase 2,Phase 3,Not Applicable
13 Antihypertensive Agents Phase 4,Phase 3,Phase 2,Not Applicable
14 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Not Applicable
15 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Not Applicable
16 Pharmaceutical Solutions Phase 4,Phase 2,Phase 3
17 Ophthalmic Solutions Phase 4,Phase 3,Phase 2
18 Adrenergic alpha-Agonists Phase 4,Phase 3,Phase 2
19 Adrenergic beta-Antagonists Phase 4,Phase 3
20 Adrenergic alpha-2 Receptor Agonists Phase 4,Phase 3
21 Anti-Arrhythmia Agents Phase 4,Phase 3
22 Adrenergic Agonists Phase 4,Phase 3,Phase 2
23 Brimonidine Tartrate Phase 4,Phase 3 70359-46-5
24 Adrenergic Agents Phase 4,Phase 3,Phase 2
25 Adrenergic Antagonists Phase 4,Phase 3
26 Cholinergic Agents Phase 4,Not Applicable
27 Muscarinic Agonists Phase 4,Not Applicable
28 Carbonic Anhydrase Inhibitors Phase 4,Not Applicable
29 Brimonidine Tartrate, Timolol Maleate Drug Combination Phase 4
30
Triamcinolone Approved, Vet_approved Phase 2, Phase 3 124-94-7 31307
31
Epinephrine Approved, Vet_approved Phase 2, Phase 3 51-43-4 5816
32
Racepinephrine Approved Phase 2, Phase 3 329-65-7 838
33 Hormones Phase 2, Phase 3
34 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2, Phase 3
35 Hormone Antagonists Phase 2, Phase 3
36 Anti-Inflammatory Agents Phase 2, Phase 3
37 glucocorticoids Phase 2, Phase 3
38 Alkylating Agents Phase 3
39 Anti-Bacterial Agents Phase 3
40 Nucleic Acid Synthesis Inhibitors Phase 3
41 Antibiotics, Antitubercular Phase 3
42 Mitomycins Phase 3
43 Triamcinolone diacetate Phase 2, Phase 3
44 triamcinolone acetonide Phase 2, Phase 3
45 Immunosuppressive Agents Phase 2, Phase 3
46 Immunologic Factors Phase 2, Phase 3,Not Applicable
47 Triamcinolone hexacetonide Phase 2, Phase 3
48 Adrenergic beta-Agonists Phase 2, Phase 3
49 Anti-Asthmatic Agents Phase 2, Phase 3
50 Respiratory System Agents Phase 2, Phase 3

Interventional clinical trials:

(show top 50) (show all 59)
# Name Status NCT ID Phase Drugs
1 Relationship Between Topiramate Use and Ocular Angle Status Unknown status NCT00153699 Phase 4 Topiramate
2 Combined Phacotube vs Phacotrabeculectomy:A Randomized Controlled Trial Unknown status NCT00273221 Phase 4
3 Travoprost 0.004% Versus Pilocarpine 1% in Patients With Chronic Angle Closure Glaucoma (CACG) Completed NCT00762645 Phase 4 Travoprost 0.004% (Travatan);Pilocarpine 1%
4 Exploratory Study Comparing Signs and Symptoms in Patients With Ocular Hypertension or Glaucoma Using Xalatan R® or Travatan Z® Completed NCT00799682 Phase 4 Xalatan;Travatan Z
5 Azopt (Brinzolamide 1.0%) Plus Travatan (Travoprost 0.004%) in Treating Patients With Chronic Angle-Closure Glaucoma (CACG) Terminated NCT00758342 Phase 4 Travoprost 0.004% + Brinzolamide 1.0%;Travoprost 0.004% + Tears Natural
6 Study of Brimonidine and Timolol Ophthalmic Solution With Latanoprost Compared With Latanoprost in Glaucoma Patients Terminated NCT01151904 Phase 4 brimonidine 0.2%/timolol 0.5% fixed combination ophthalmic solution;latanoprost
7 Argon Laser Peripheral Iridoplasty for Primary Angle Closure Glaucoma Unknown status NCT00980473 Phase 3 Travatan/ Timolol/Azopt
8 Intraocular Pressure (IOP) Lowering Effect of Selective Laser Trabeculoplasty Versus Prostaglandin Analogues in Angle Closure Glaucoma Unknown status NCT01004900 Phase 3 Travoprost/ Timolol/ Azopt/ Brimonidine
9 A Safety and Efficacy Study of Travoprost 0.004% Compared to Latanoprost 0.005% in Patients With Chronic Angle-Closure Glaucoma Completed NCT00051181 Phase 3 Travoprost (0.004%);Latanoprost (0.005%)
10 Oculusgen (Ologen) Glaucoma MMC Control in Estonia Completed NCT00524758 Phase 3 MMC in Trabeculectomy
11 Will the Use of Triesence During Glaucoma Surgery Provide Lower Eye Pressure and Improve the Results of the Surgery? Completed NCT00853905 Phase 2, Phase 3 Triesence;balanced salt solution BSS
12 Safety and Effectiveness of the XEN45 Glaucoma Treatment System in Patients With Angle Closure Glaucoma Recruiting NCT03362931 Phase 3
13 Prophylactic Topical Epinephrine to Reduce Bleeding in Transbronchial Lung Biopsies Recruiting NCT03126968 Phase 2, Phase 3 Topical epinephrine;Placebos
14 A Study to Assess the Effect of Rho-Kinase Inhibitor AR-12286 Ophthalmic Solution 0.5% and 0.7% in Patients With Chronic Angle-closure Glaucoma Unknown status NCT02152774 Phase 2 Rho-Kinase Inhibitor
15 Use of Topical Euphrasia, a Homeopathic Remedy in Ophthalmology Unknown status NCT02416128 Phase 2 Euphrasia;Prednisolone acetate
16 Phase IIA Double-Masked Randomized Sham-Controlled Trial of QPI-1007 Delivered by a Single Intravitreal Injection to Subjects With Acute Primary Angle-Closure Glaucoma (APACG) Completed NCT01965106 Phase 2 QPI-1007 Injection;(including placebo)
17 Comparison of Bimatoprost and Latanoprost in Patients With Chronic Angle-Closure Glaucoma: A Randomized Cross-Over Study Unknown status NCT00567788 Not Applicable Latanoprost-Bimatoprost;Bimatoporost-Latanoprost
18 The Genetic Study of Primary Angle-Closure Glaucoma Unknown status NCT00155857
19 Optical Coherence Tomography Quantitative Analysis of Changes in Anterior Chamber After Laser Peripheral Lridotomy Unknown status NCT02279472 Not Applicable
20 Prevalence of Angle Closure in Caucasian Hyperopes Unknown status NCT00823706
21 Angle Closure (Glaucoma) in Caucasians Unknown status NCT02054403
22 Clinical Study of LPI on Different Sites of Iris Unknown status NCT02870504 Not Applicable
23 Clinical Study of LPI With Different Laser Wavelengths Unknown status NCT02901730 Not Applicable
24 Protective Effect of Phenytoin on Glaucoma Unknown status NCT00739154
25 Comparison of Phacotrabeculectomy and Trabeculectomy in the Treatment of Primary Angle-closure Glaucoma (PACG) Completed NCT01298635 Not Applicable
26 Prophylactic Peripheral Iridectomy Prevents Aphakic Angle-closure Glaucoma Completed NCT03610295 Not Applicable
27 Prevalence of Corneal Astigmatism Before Glaucoma Surgery in Chinese Patients With Primary Angle-closure Glaucoma Completed NCT03159780
28 Comparison of Anterior Chamber Paracentesis and Conventional Mannitol Infusion in Patients With Primary Acute Angle-closure Glaucoma Completed NCT01266343
29 Primary Angle Closure Glaucoma and Aqueous Dynamics Completed NCT00719290 Not Applicable
30 Laser Iridotomy Versus Phacoemulsification in Acute Angle Closure Completed NCT00350428 Not Applicable
31 An Open Label Study Assessing the 24-hour Intraocular Pressure Pattern in PAC and PACG Patients, Before and After Laser Peripheral Iridotomy Completed NCT01906138 Not Applicable
32 Phacoemulsification Versus Phacoemulsification With Micro-bypass Stent Completed NCT03647033 Not Applicable
33 Cataract Surgery Combined With Endoscopic Goniosynechialysis for Advanced Primary Angle Closure Glaucoma Completed NCT03686072 Not Applicable
34 Comparison of Gonioscopy With Cirrus and Visante Completed NCT01895686
35 Dysphotopsia Following Laser Peripheral Iridotomy Completed NCT01758237 Not Applicable
36 Comparing Nd:YAG Laser and Sequential Double Frequency YAG-Nd:YAG Laser Iridotomy Completed NCT02474238 Not Applicable
37 Water Drinking Test in Patients With Occludable Angle Completed NCT02613533 Not Applicable
38 Prospective Evaluation of the Efficacy of Pascal Laser Iridotomy and Pascal Laser Peripheral Iridoplasty: A Pilot Study Completed NCT01020071 Not Applicable
39 Short-term Outcomes of Iridoplasty for Persistent Angle Closure Despite Patent Iridotomies Completed NCT02199158 Not Applicable
40 Biometry of Occult Lens Subluxation Misdiagnosed as Primary Acute Angle Closed Glaucoma Completed NCT03752710
41 Comparison of Superior vs Nasal/Temporal Laser Peripheral Iridotomy in Primary Angle Closure Completed NCT03187821 Not Applicable
42 Sequential Laser Iridotomy Using Argon and Q-Switched 532 nm Frequency Doubled Neodymium Yag Laser: A Pilot Study Completed NCT00452998 Not Applicable
43 Role of Polymorphisms in the IL-1 Gene Cluster Completed NCT00346541
44 Immediate Anterior Chamber Paracentesis With A 30-Gauge Needle for Acute Primary Angle - Closure Completed NCT01923454 Not Applicable Acetazolamide
45 Will Listening to Music Make it Easier to Take a Visual Field Test? Completed NCT01027039
46 A Drug Utilisation Post-authorisation Study of New Users of Aclidinium Bromide (Monotherapy or in Combination) Completed NCT03333018 Aclidinium bromide;Aclidinium bromide/formoterol;Other COPD medication
47 Artificial Intelligence Screening on Patients With Primary Angle Closure Glaucoma Recruiting NCT03611387
48 Study on Ex-PRESS Implantation Combined With Phacoemulsification in Primary Angle-closure Glaucoma Recruiting NCT03323138 Not Applicable
49 Investigating the Genetic Basis of Pseudoexfoliation Syndrome and Angle-closure Glaucoma Recruiting NCT03423758
50 Visual Field Defect Estimation Using Sequentially Optimized Reconstruction Strategy on Healthy and Glaucoma Subjects Recruiting NCT03325751

Search NIH Clinical Center for Primary Angle-Closure Glaucoma

Inferred drug relations via UMLS 73 / NDF-RT 51 :
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Genetic Tests for Primary Angle-Closure Glaucoma

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Anatomical Context for Primary Angle-Closure Glaucoma

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MalaCards organs/tissues related to Primary Angle-Closure Glaucoma:

41
Eye, Testes, Retina, Brain, Endothelial, Neutrophil, Bone
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Publications for Primary Angle-Closure Glaucoma

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Articles related to Primary Angle-Closure Glaucoma:

(show top 50) (show all 441)
# Title Authors Year
1
Combined Phacoemulsification and Goniosynechialysis under an Endoscope for Chronic Primary Angle-Closure Glaucoma. ( 29576881 )
2018
2
Long Term Evaluation of Specular Microscopic Changes Following Nd YAG Iridotomy in Chronic Primary Angle Closure Glaucoma Eyes. ( 29750720 )
2018
3
Aqueous humor protein dysregulation in primary angle-closure glaucoma. ( 29536409 )
2018
4
Long-Term Evalution of Specular Microscopic Changes Following Nd: YAG Iridotomy in Chronic Primary Angle-Closure Glaucoma Eyes. ( 29750721 )
2018
5
Phacoemulsification with Intraocular Implantation of Lens, Endocyclophotocoagulation, and Endoscopic-Goniosynechialysis (PIECES): A Combined Technique for the Management of Extensive Synechial Primary Angle Closure Glaucoma. ( 29861582 )
2018
6
Trabeculectomy With Mitomycin-C: Outcomes and Risk Factors for Failure in Primary Angle-closure Glaucoma. ( 29240597 )
2018
7
Simplifying "target" intraocular pressure for different stages of primary open-angle glaucoma and primary angle-closure glaucoma. ( 29582808 )
2018
8
The Seasonality of Acute Attack of Primary Angle-Closure Glaucoma in Beijing, China. ( 29507343 )
2018
9
Clear lens extraction for the management of primary angle closure glaucoma: surgical technique and refractive outcomes in the EAGLE cohort. ( 29453222 )
2018
10
Prospective Study on Ex-PRESS Implantation Combined with Phacoemulsification in Primary Angle-Closure Glaucoma Coexisting Cataract: 3-Year Results. ( 29718724 )
2018
11
Reduced Retinal Vessel Density in Primary Angle Closure Glaucoma: A Quantitative Study Using Optical Coherence Tomography Angiography. ( 29419642 )
2018
12
Evaluation of Primary Angle-Closure Glaucoma Susceptibility Loci in Patients with Early Stages of Angle-Closure Disease. ( 29310965 )
2018
13
Differences between fellow eyes of acute and chronic primary angle closure (glaucoma): An ultrasound biomicroscopy quantitative study. ( 29447247 )
2018
14
Asymmetric Patterns of Visual Field Defect in Primary Open-Angle and Primary Angle-Closure Glaucoma. ( 29625450 )
2018
15
Clinical Features and Efficacy of Lens Surgery in Patients with Lens Subluxation Misdiagnosed as Primary Angle-Closure Glaucoma. ( 30426797 )
2018
16
Predictors of Outcome in Selective Laser Trabeculoplasty: A Long-term Observation Study in Primary Angle-closure Glaucoma After Laser Peripheral Iridotomy Compared With Primary Open-angle Glaucoma. ( 30113512 )
2018
17
Rates of Visual Field Loss in Primary Open-Angle Glaucoma and Primary Angle-Closure Glaucoma: Asymmetric Patterns. ( 30513532 )
2018
18
Primary angle-closure glaucoma, a rare but severe complication after blepharoplasty: Case report and review of the literature. ( 30037202 )
2018
19
Trabeculectomy With Mitomycin-C: Outcomes and Risk Factors for Failure in Primary Angle-closure Glaucoma. ( 30095605 )
2018
20
Altered whole-brain gray matter volume in primary angle closure glaucoma patients: a voxel-based morphometry study. ( 30199440 )
2018
21
Primary angle closure and primary angle closure glaucoma in retinal vein occlusion. ( 30239140 )
2018
22
Primary Angle Closure Glaucoma with Normal Intraocular Pressure at the First Visit: Its Prevalence and Ocular Characteristics. ( 30300309 )
2018
23
Association of Genes implicated in primary angle-closure Glaucoma and the ocular biometric parameters of anterior chamber depth and axial length in a northern Chinese population. ( 30348125 )
2018
24
Genotype-ocular biometry correlation analysis of eight primary angle closure glaucoma susceptibility loci in a cohort from Northern China. ( 30399154 )
2018
25
Evaluation of Anterior Segment Parameters in Pseudoexfoliative Glaucoma, Primary Angle-Closure Glaucoma, and Healthy Eyes. ( 30405943 )
2018
26
Inflammatory Cytokine Profiles in Eyes with Primary Angle-Closure Glaucoma. ( 30429240 )
2018
27
Cigarette Smoking on Severity of Primary Angle Closure Glaucoma in Malay Patients. ( 30461551 )
2018
28
Choroidal microvascular dropout in primary angle closure glaucoma. ( 30552893 )
2018
29
Long-chain unsaturated fatty acids as possible important metabolites for primary angle-closure glaucoma based on targeted metabolomic analysis. ( 28214354 )
2017
30
Increased aquaporin-1 levels in lens epithelial cells with primary angle-closure glaucoma. ( 28730113 )
2017
31
The diagnostic value of white blood cell, neutrophil, neutrophil-to-lymphocyte ratio, and lymphocyte-to-monocyte ratio in patients with primary angle closure glaucoma. ( 28978173 )
2017
32
Association between coagulation function and patients with primary angle closure glaucoma: a 5-year retrospective case-control study. ( 29102986 )
2017
33
Visual Field Progression in Patients with Primary Angle-Closure Glaucoma Using Pointwise Linear Regression Analysis. ( 28372858 )
2017
34
Long-Term Outcomes of Primary Trabeculectomy in Diabetic Patients without Retinopathy with Primary Angle-Closure Glaucoma. ( 28337343 )
2017
35
Comparison of self-measured diurnal intraocular pressure profiles using rebound tonometry between primary angle closure glaucoma and primary open angle glaucoma patients. ( 28333942 )
2017
36
Evaluation of potential risk factors for development of primary angle-closure glaucoma in Bouviers des Flandres. ( 28001106 )
2017
37
Early lens extraction with intraocular lens implantation for the treatment of primary angle closure glaucoma: an economic evaluation based on data from the EAGLE trial. ( 28087548 )
2017
38
Phacoemulsification versus laser iridotomy in primary angle closure glaucoma. A difficult decision. ( 28610807 )
2017
39
Vessel Density and Structural Measurements of Optical Coherence Tomography in Primary Angle Closure and Primary Angle Closure Glaucoma. ( 28254626 )
2017
40
Association of Plasma Complement C3 Levels With Primary Angle-Closure Glaucoma in Older Women. ( 28134964 )
2017
41
Genetic Association of the PARL-ABCC5-HTR3D-HTR3C Locus With Primary Angle-Closure Glaucoma in Chinese. ( 28813580 )
2017
42
Optical Coherence Tomography Angiography of the Peripapillary Retina in Primary Angle-Closure Glaucoma. ( 28797550 )
2017
43
Ocular Biometry in Primary Angle-Closure Glaucoma Associated with Retinitis Pigmentosa. ( 29464115 )
2017
44
Resident-performed laser peripheral iridotomy in primary angle closure, primary angle closure suspects, and primary angle closure glaucoma. ( 29081648 )
2017
45
Primary angle closure glaucoma (PACG) susceptibility gene PLEKHA7 encodes a novel Rac1/Cdc42 GAP that modulates cell migration and blood-aqueous barrier function. ( 29016860 )
2017
46
Decision-making Impairments in Primary Angle-closure Glaucoma Patients. ( 28584204 )
2017
47
Trabecular Meshwork Height in Primary Open-Angle Glaucoma Versus Primary Angle-Closure Glaucoma. ( 28887118 )
2017
48
Treatment of primary angle-closure glaucoma: Does early lens extraction help? ( 28816215 )
2017
49
A new approach for the management of primary angle-closure glaucoma after EAGLE trial. ( 28522116 )
2017
50
Associated factors of acute primary angle closure glaucoma in a sub-group of Chinese people: comparison between attack eyes and normal controls. ( 29097742 )
2017
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Variations for Primary Angle-Closure Glaucoma

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Expression for Primary Angle-Closure Glaucoma

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Search GEO for disease gene expression data for Primary Angle-Closure Glaucoma.
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Pathways for Primary Angle-Closure Glaucoma

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GO Terms for Primary Angle-Closure Glaucoma

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Cellular components related to Primary Angle-Closure Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix GO:0031012 8.92 COL11A1 KERA MMP9 MYOC

Biological processes related to Primary Angle-Closure Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 collagen fibril organization GO:0030199 9.26 COL11A1 CYP1B1
2 endodermal cell differentiation GO:0035987 9.16 COL11A1 MMP9
3 visual perception GO:0007601 9.02 COL11A1 CYP1B1 KERA MFRP VSX2
4 regulation of reactive oxygen species metabolic process GO:2000377 8.96 CYP1B1 PARL

Molecular functions related to Primary Angle-Closure Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 frizzled binding GO:0005109 8.62 MYOC ZNRF3
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Sources for Primary Angle-Closure Glaucoma

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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