MCID: PRM243
MIFTS: 19

Primary Bone Cancer

Categories: Rare diseases, Bone diseases, Cancer diseases

Aliases & Classifications for Primary Bone Cancer

MalaCards integrated aliases for Primary Bone Cancer:

Name: Primary Bone Cancer 53
Primary Malignant Neoplasm of Bone 53 73
Primary Bone Osteosarcoma 73
Rare Bone Tumor 53

Classifications:



External Ids:

Summaries for Primary Bone Cancer

MalaCards based summary : Primary Bone Cancer, also known as primary malignant neoplasm of bone, is related to chondrosarcoma and bone cancer. An important gene associated with Primary Bone Cancer is MRC2 (Mannose Receptor C Type 2). The drug Radium Ra 223 dichloride has been mentioned in the context of this disorder. Affiliated tissues include bone and prostate.

Related Diseases for Primary Bone Cancer

Diseases related to Primary Bone Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 chondrosarcoma 10.8
2 bone cancer 10.1
3 aging 9.7
4 angiosarcoma 9.6
5 sarcoma 9.6
6 histiocytoma 9.5
7 fibrous histiocytoma 9.5
8 chordoma 9.5
9 osteoblastoma 9.5
10 ossifying fibroma 9.5

Graphical network of the top 20 diseases related to Primary Bone Cancer:



Diseases related to Primary Bone Cancer

Symptoms & Phenotypes for Primary Bone Cancer

Drugs & Therapeutics for Primary Bone Cancer

Drugs for Primary Bone Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Radium Ra 223 dichloride Approved, Investigational Phase 4,Phase 1,Phase 2 444811-40-9

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Radium-223 Dichloride Long-term Follow-up Program Recruiting NCT02312960 Phase 4
2 Re-treatment Safety of Radium-223 Dichloride in Castration-resistant Prostate Cancer With Bone Metastases Completed NCT01934790 Phase 1, Phase 2 Radium-223 dichloride (Xofigo, BAY88-8223)
3 The Osteosarcoma Biobank in Peking University People's Hospital Not yet recruiting NCT03362086
4 The Neurofibromatosis-associated Tumor Biobank Not yet recruiting NCT03359304

Search NIH Clinical Center for Primary Bone Cancer

Genetic Tests for Primary Bone Cancer

Anatomical Context for Primary Bone Cancer

MalaCards organs/tissues related to Primary Bone Cancer:

41
Bone, Prostate

Publications for Primary Bone Cancer

Articles related to Primary Bone Cancer:

(show all 11)
# Title Authors Year
1
Socio-economic patterning in early mortality of patients aged 0-49 years diagnosed with primary bone cancer in Great Britain, 1985-2008. ( 29414632 )
2018
2
Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180. ( 26466547 )
2015
3
Cured of primary bone cancer, but at what cost: a qualitative study of functional impairment and lost opportunities. ( 25949211 )
2015
4
Primary bone cancer in Leonbergers may be associated with a higher bodyweight during adolescence. ( 25732913 )
2015
5
Population-based registries are important in sarcoma: an editorial regarding "incidence patterns of primary bone cancer in Taiwan (2003-2010)". ( 24743911 )
2014
6
Incidence patterns of primary bone cancer in taiwan (2003-2010): a population-based study. ( 24723225 )
2014
7
Primary bone cancer. ( 24251490 )
2013
8
Age-period-cohort analysis of primary bone cancer incidence rates in the United States (1976-2005). ( 21724855 )
2011
9
"So, are you back to work yet?" Re-conceptualizing 'work' and 'return to work' in the context of primary bone cancer. ( 18851893 )
2008
10
Primary bone osteosarcoma in the pediatric age: state of the art. ( 16860938 )
2006
11
Primary bone cancer incidence in black and white residents of New York State. ( 3857961 )
1985

Variations for Primary Bone Cancer

Expression for Primary Bone Cancer

Search GEO for disease gene expression data for Primary Bone Cancer.

Pathways for Primary Bone Cancer

GO Terms for Primary Bone Cancer

Sources for Primary Bone Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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