MCID: PRM339
MIFTS: 31

Primary Glomerular Disease

Categories: Nephrological diseases, Rare diseases

Aliases & Classifications for Primary Glomerular Disease

MalaCards integrated aliases for Primary Glomerular Disease:

Name: Primary Glomerular Disease 58

Classifications:

Orphanet: 58  
Rare renal diseases


External Ids:

Orphanet 58 ORPHA102373

Summaries for Primary Glomerular Disease

MalaCards based summary : Primary Glomerular Disease is related to glomerulonephritis and rapidly progressive glomerulonephritis. An important gene associated with Primary Glomerular Disease is ALB (Albumin), and among its related pathways/superpathways are Degradation of the extracellular matrix and Cellular senescence (KEGG). The drugs Losartan and Angiotensin II have been mentioned in the context of this disorder. Affiliated tissues include kidney, bone and prostate, and related phenotypes are neoplasm and renal/urinary system

Related Diseases for Primary Glomerular Disease

Diseases in the Glomerular Disease family:

Secondary Glomerular Disease Primary Glomerular Disease

Diseases related to Primary Glomerular Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 102, show less)
# Related Disease Score Top Affiliating Genes
1 glomerulonephritis 30.9 TGFB1 ALB
2 rapidly progressive glomerulonephritis 30.0 TGFB1 ALB
3 end stage renal failure 29.9 TGFB1 ALB
4 alport syndrome 29.8 TGFB1 ALB
5 chronic kidney disease 29.1 TGFB1 SERPINE1 ALB
6 kidney disease 29.1 TGFB1 SERPINE1 ALB
7 vascular disease 28.8 TGFB1 SERPINE1 ALB
8 glomerulopathy with fibronectin deposits 2 11.2
9 glomerular disease 10.6
10 membranous nephropathy 10.5
11 iga glomerulonephritis 10.5
12 nephrotic syndrome 10.4
13 focal segmental glomerulosclerosis 10.4
14 lipoid nephrosis 10.4
15 membranoproliferative glomerulonephritis 10.3
16 proliferative glomerulonephritis 10.3
17 mesangial proliferative glomerulonephritis 10.2
18 crescentic glomerulonephritis 10.1
19 kidney hypertrophy 10.1 TGFB1 ALB
20 facial paralysis 10.1 TGFB1 ALB
21 giardiasis 10.1 TGFB1 ALB
22 communicating hydrocephalus 10.1 TGFB1 ALB
23 microvascular complications of diabetes 3 10.0 TGFB1 ALB
24 obstructive nephropathy 10.0 TGFB1 ALB
25 systemic lupus erythematosus 10.0
26 biliary atresia 10.0 TGFB1 ALB
27 dupuytren contracture 10.0 TGFB1 DCN
28 vesicoureteral reflux 1 10.0 TGFB1 ALB
29 nephrogenic systemic fibrosis 10.0 TGFB1 DCN
30 heart valve disease 10.0 TGFB1 ALB
31 peyronie's disease 10.0 TGFB1 DCN
32 schistosomiasis 10.0 TGFB1 ALB
33 bullous keratopathy 10.0 TGFB1 DCN
34 localized scleroderma 9.9 TGFB1 DCN
35 hydronephrosis 9.9 TGFB1 ALB
36 crouzon syndrome 9.9 TGFB1 DCN
37 nephrosclerosis 9.9
38 lupus erythematosus 9.9
39 dense deposit disease 9.9
40 mesangioproliferative glomerulopathy 9.9
41 gingival overgrowth 9.9 TGFB1 DCN
42 corneal disease 9.9 DCN ALB
43 marfan syndrome 9.8 TGFB1 DCN
44 chondromyxoid fibroma 9.8 TGFB1 SERPINE1
45 pulmonary fibrosis 9.8 TGFB1 SERPINE1
46 pulmonary artery disease 9.8 SERPINE1 ALB
47 eclampsia 9.8 SERPINE1 ALB
48 hepatic vascular disease 9.8 SERPINE1 ALB
49 chronic venous insufficiency 9.8 TGFB1 SERPINE1
50 venous insufficiency 9.8 TGFB1 SERPINE1
51 apnea, obstructive sleep 9.8 SERPINE1 ALB
52 endocrine pancreas disease 9.8 SERPINE1 ALB
53 paranasal sinus disease 9.8 TGFB1 SERPINE1
54 intermittent claudication 9.8 SERPINE1 ALB
55 intracranial hypertension 9.8 SERPINE1 ALB
56 vein disease 9.8 SERPINE1 ALB
57 coronary stenosis 9.8 SERPINE1 ALB
58 severe pre-eclampsia 9.8 SERPINE1 ALB
59 pneumoconiosis 9.8 TGFB1 SERPINE1
60 blood coagulation disease 9.8 SERPINE1 ALB
61 iga nephropathy 1 9.8
62 wilms tumor 5 9.8
63 nonaka myopathy 9.8
64 hepatitis c virus 9.8
65 thrombosis 9.8
66 hepatitis c 9.8
67 myopathy 9.8
68 diffuse glomerulonephritis 9.8
69 placenta disease 9.8
70 polyarteritis nodosa 9.8
71 cytomegalovirus infection 9.8
72 idiopathic nephrotic syndrome 9.8
73 homocysteinemia 9.8 SERPINE1 ALB
74 endocarditis 9.8 SERPINE1 ALB
75 idiopathic interstitial pneumonia 9.7 TGFB1 SERPINE1
76 pulmonary embolism 9.7 SERPINE1 ALB
77 peripheral vascular disease 9.7 SERPINE1 ALB
78 peritonitis 9.7 SERPINE1 ALB
79 microvascular complications of diabetes 5 9.7 SERPINE1 ALB
80 patent foramen ovale 9.7 SERPINE1 ALB
81 overnutrition 9.7 SERPINE1 ALB
82 glucose metabolism disease 9.6 SERPINE1 ALB
83 scoliosis 9.6 TGFB1 DCN ALB
84 atherosclerosis susceptibility 9.5 SERPINE1 ALB
85 arteries, anomalies of 9.5 SERPINE1 ALB
86 muscular dystrophy 9.5 TGFB1 DCN ALB
87 thrombophlebitis 9.4 TGFB1 SERPINE1 ALB
88 ureteral disease 9.4 TGFB1 SERPINE1 ALB
89 urinary tract obstruction 9.4 TGFB1 SERPINE1 ALB
90 portal hypertension 9.4 TGFB1 SERPINE1 ALB
91 renal fibrosis 9.4 TGFB1 SERPINE1 ALB
92 interstitial lung disease 9.4 TGFB1 SERPINE1 ALB
93 pulmonary fibrosis, idiopathic 9.4 TGFB1 SERPINE1 ALB
94 aplastic anemia 9.4 TGFB1 SERPINE1 ALB
95 glucose intolerance 9.4 SERPINE1 ALB
96 pre-eclampsia 9.3 SERPINE1 DCN ALB
97 osteoporosis 9.3 TGFB1 SERPINE1 ALB
98 acquired metabolic disease 9.2 SERPINE1 ALB
99 dilated cardiomyopathy 9.2 TGFB1 SERPINE1 ALB
100 malaria 9.2 TGFB1 SERPINE1 ALB
101 myocardial infarction 9.0 TGFB1 SERPINE1 DCN ALB
102 ovarian cancer 8.8 TGFB1 SERPINE1 DCN ALB

Graphical network of the top 20 diseases related to Primary Glomerular Disease:



Diseases related to Primary Glomerular Disease

Symptoms & Phenotypes for Primary Glomerular Disease

MGI Mouse Phenotypes related to Primary Glomerular Disease:

45 (showing 2, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.26 ALB DCN SERPINE1 TGFB1
2 renal/urinary system MP:0005367 8.92 ALB DCN SERPINE1 TGFB1

Drugs & Therapeutics for Primary Glomerular Disease

Drugs for Primary Glomerular Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 47, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Losartan Approved Phase 4 114798-26-4 3961
2
Angiotensin II Approved, Investigational Phase 4 68521-88-0, 11128-99-7, 4474-91-3 172198
3
Tacrolimus Approved, Investigational Phase 4 104987-11-3 445643 439492 6473866
4 Antihypertensive Agents Phase 4
5 Immunoglobulin A Phase 4
6 Cassava Phase 4
7 Anti-Arrhythmia Agents Phase 4
8 Angiotensin Receptor Antagonists Phase 4
9 Angiotensin II Type 1 Receptor Blockers Phase 4
10 Angiotensinogen Phase 4
11 Giapreza Phase 4
12 Hormones Phase 4
13 Immunosuppressive Agents Phase 4
14 Immunologic Factors Phase 4
15 Melanocyte-Stimulating Hormones Phase 4
16 Pharmaceutical Solutions Phase 4
17 Adrenocorticotropic Hormone Phase 4
18 Hormone Antagonists Phase 4
19 beta-endorphin Phase 4
20 Calcineurin Inhibitors Phase 4
21
Epoprostenol Approved Phase 2, Phase 3 61849-14-7, 35121-78-9 5280427 5282411
22
Mycophenolic acid Approved Phase 3 24280-93-1 446541
23
Azathioprine Approved Phase 3 446-86-6 2265
24 Beraprost Investigational Phase 2, Phase 3 88430-50-6
25 Tezosentan Investigational Phase 2, Phase 3 180384-57-0
26 Platelet Aggregation Inhibitors Phase 2, Phase 3
27 Vasodilator Agents Phase 2, Phase 3
28 Antibiotics, Antitubercular Phase 3
29 Anti-Infective Agents Phase 3
30 Anti-Bacterial Agents Phase 3
31 Antimetabolites Phase 3
32 Antirheumatic Agents Phase 3
33 Antitubercular Agents Phase 3
34
Ergocalciferol Approved, Nutraceutical 50-14-6 5280793
35
Vitamin D Approved, Nutraceutical, Vet_approved 1406-16-2
36
Vitamin D3 Approved, Nutraceutical 67-97-0 6221 5280795
37
Calcium Approved, Nutraceutical 7440-70-2 271
38 Trace Elements
39 Vitamins
40 Micronutrients
41 Nutrients
42 Ergocalciferols
43 Calciferol
44 Antibodies
45 Immunoglobulins
46 Vitamin D2
47 Calcium, Dietary

Interventional clinical trials:

(showing 7, show less)
# Name Status NCT ID Phase Drugs
1 Efficacy and Safety of Abelmoschus Manihot for IgA Nephropathy: a Multicentre, Double-blind, Double-dummy, Randomized Controlled Trial Unknown status NCT02231125 Phase 4 Losartan;Abelmoschus manihot
2 A Multicenterer, Comparative Safety Andof ACTHar Gel Alone or in Cwith oe Urinary in Patients Positive Fibrillary Glomerulopathy Recruiting NCT04080076 Phase 4 Acthar 80 UNT/ML Injectable Solution;Tacrolimus capsule
3 TRK-100STP PhaseIIb/III Clinical Study - Chronic Renal Failure (Primary Glomerular Disease/Nephrosclerosis) Completed NCT01090037 Phase 2, Phase 3 TRK-100STP high dose;TRK-100STP low dose;Placebo
4 A Randomized, Multicenter Study to Assess the Efficacy on Diseases Activity of Enteric-coated Mycophenolate Sodium Versus Continuation of Azathioprine in Patients With Systemic Lupus Erythematosus on Azathioprine Maintenance Therapy. Terminated NCT00504244 Phase 3 switch to Myfortic;continuation of azathioprine
5 TRK-100STP PhaseII Clinical Study -Chronic Renal Failure (Primary Glomerular Disease/Nephrosclerosis) Completed NCT02480751 Phase 2 Beraprost;Placebo
6 Histological and Clinical Biomarkers to Predict the Progression of IgA Nephropathy Completed NCT02529722
7 Pilot Study: Efficacy and Safety of Vitamin D Supplementation in Glomerular Disease Completed NCT01835639

Search NIH Clinical Center for Primary Glomerular Disease

Genetic Tests for Primary Glomerular Disease

Anatomical Context for Primary Glomerular Disease

MalaCards organs/tissues related to Primary Glomerular Disease:

40
Kidney, Bone, Prostate, B Cells

Publications for Primary Glomerular Disease

Articles related to Primary Glomerular Disease:

(showing 255, show less)
# Title Authors PMID Year
1
Trends of renal diseases in Germany: review of a regional renal biopsy database from 1990 to 2013. 61
31808446 2019
2
Effect of the traditional Chinese medicine Qi Teng Xiao Zhuo granules on chronic glomerulonephritis rats studied by using long noncoding RNAs expression profiling. 61
31821871 2019
3
Tubular injury triggers podocyte dysfunction by β-catenin-driven release of MMP-7. 61
31743113 2019
4
Recent advances in risk prediction, therapeutics and pathogenesis of IgA nephropathy. 61
31142099 2019
5
Hemodialysis in children: how, when and why. 61
31630720 2019
6
Clinical outcomes and effects of treatment in older patients with idiopathic membranous nephropathy. 61
31408925 2019
7
[Analysis on diagnosis rate of chronic kidney disease in hospitalized pediatric patients]. 61
31530351 2019
8
Obesity is not associated with progression to end stage renal disease in patients with biopsy-proven glomerular diseases. 61
31266462 2019
9
Gene polymorphism and risk of idiopathic membranous nephropathy. 61
31075233 2019
10
Structural prediction of antibody-APRIL complexes by computational docking constrained by antigen saturation mutagenesis library data. 61
30761651 2019
11
Urine markers of renal tubular injury in idiopathic membranous nephropathy: A cross sectional study. 61
30684459 2019
12
Effects of Sustained-Release Beraprost in Patients With Primary Glomerular Disease or Nephrosclerosis: CASSIOPEIR Study Results. 61
31119846 2019
13
High serum IgA/C3 ratio better predicts a diagnosis of IgA nephropathy among primary glomerular nephropathy patients with proteinuria ≤ 1 g/d: an observational cross-sectional study. 61
31039758 2019
14
LncRNAs expression in adriamycin-induced rats reveals the potential role of LncRNAs contributing to chronic glomerulonephritis pathogenesis. 61
30458286 2019
15
Chondroitin sulfate degradation and eicosanoid metabolism pathways are impaired in focal segmental glomerulosclerosis: Experimental confirmation of an in silico prediction. 61
31334040 2019
16
Serum immunoglobulin G provides early risk prediction in immunoglobulin A nephropathy. 61
30415190 2019
17
Immunoglobulin A Nephropathy. Recurrence After Renal Transplantation. 61
31275309 2019
18
Changing Protein Permeability with Nephron Loss: Evidence for a Human Remnant Nephron Effect. 61
31269482 2019
19
Tunnelled haemodialysis catheters in central Free State: Epidemiology and complications. 61
31824740 2019
20
Pattern of glomerular disease and clinicopathological correlation: A single-center study from Eastern Nepal. 61
30588974 2018
21
Clinicopathological features of pediatric renal biopsies in the plateau regions of China. 61
30027800 2018
22
Angiopoietin-2: A Potential Mediator of the Glycocalyx Injury in Adult Nephrotic Patients. 61
30384404 2018
23
Successful treatment with rituximab of immunotactoid glomerulopathy exhibiting nephrotic syndrome
. 61
30049299 2018
24
Epidemiology of IgA Nephropathy: A Global Perspective. 61
30177015 2018
25
U6 can be used as a housekeeping gene for urinary sediment miRNA studies of IgA nephropathy. 61
30022109 2018
26
The Spectrum of Biopsy-Proven Glomerular Diseases among Children in China: A National, Cross-Sectional Survey. 61
29915132 2018
27
The Genetic and Environmental Factors of Primary Membranous Nephropathy: An Overview from China. 61
29998121 2018
28
First-year GFR slope and long-term renal outcome in IgA nephropathy. 61
29660832 2018
29
Primary IgA nephropathy in the Kashmiri population. 61
29970746 2018
30
Fibrillary glomerulonephritis in an HIV patient without concurrent hepatitis C infection: Case report and review of the literature
. 61
29578397 2018
31
Characteristics of Patients Initializing Peritoneal Dialysis Treatment From 2007 to 2014: Analysis From Henan Peritoneal Dialysis Registry data. 61
29891748 2018
32
Liddle's-like syndrome associated with nephrotic syndrome secondary to membranous nephropathy: the first case report. 61
29792170 2018
33
Fibrillary Glomerulonephritis in a Patient with Sjogren's Syndrome. 61
29922524 2018
34
Evaluation of serum soluble urokinase plasminogen activator receptor as a marker for steroid-responsiveness in children with primary nephrotic syndrome. 61
29657195 2018
35
Potential role of lncRNAs in contributing to pathogenesis of chronic glomerulonephritis based on microarray data. 61
29199037 2018
36
Molecular Mechanisms of Proteinuria in Focal Segmental Glomerulosclerosis. 61
29713631 2018
37
DnaJ Heat Shock Protein Family B Member 9 Is a Novel Biomarker for Fibrillary GN. 61
29097623 2018
38
Distribution of glomerular diseases in Taiwan: preliminary report of National Renal Biopsy Registry-publication on behalf of Taiwan Society of Nephrology. 61
29320993 2018
39
Fibrillary Glomerulonephritis in Primary Sjogren's Syndrome: A Rare Cause of Renal Failure. 61
29196420 2017
40
Recurrent glomerular disease after kidney transplantation. 61
28832357 2017
41
ANCA-positive IgA nephropathy without necrotising or crescentic glomerulonephritis: a clinical conundrum. 61
29170179 2017
42
Symptomatic fracture risk in the renal replacement therapy population. 61
27257273 2017
43
Nephrotic syndrome in pregnancy poses risks with both maternal and fetal complications. 61
28233609 2017
44
Clinicopathological Analysis of Glomerular Disease of Adult Onset Nephrotic Syndrome in an Indian Cohort- A Retrospective Study. 61
28658768 2017
45
Abelmoschus manihot - a traditional Chinese medicine versus losartan potassium for treating IgA nephropathy: study protocol for a randomized controlled trial. 61
28395659 2017
46
Fibrillary glomerulonephritis presenting as crescentic glomerulonephritis. 61
28356674 2017
47
Analysis of patients with end-stage renal disease on dialysis in Tabuk City, Saudi Arabia: A single-center, three-year retrospective study. 61
28352019 2017
48
Increasing prevalence of membranous nephropathy in patients with primary glomerular diseases: A cross-sectional study in China. 61
26854278 2017
49
Pregnancy Outcomes in Patients with Glomerular Disease Attending a Single Academic Center in North Carolina. 61
28445873 2017
50
Is there a role for immunosuppression in immunoglobulin A nephropathy? 61
28391341 2017
51
Unwinding focal segmental glomerulosclerosis. 61
28491286 2017
52
Tubular urinary indexes reliably distinguish between primary tubulointerstitial and primary glomerular diseases in patients referred for kidney biopsy. 61
28601117 2017
53
The effects of Qi Teng Xiao Zhuo granules, traditional Chinese medicine, on the expression of genes in chronic glomerulonephritis rats. 61
27497640 2016
54
Twenty-eight-year review of childhood renal diseases from renal biopsy data: A single centre in China. 61
26698187 2016
55
Urinary fibrinogen and renal tubulointerstitial fibrinogen deposition: Discriminating between primary FSGS and minimal change disease. 61
27539323 2016
56
Functional networks of aging markers in the glomeruli of IgA nephropathy: a new therapeutic opportunity. 61
27127888 2016
57
Simultaneous occurrence of fibrillary glomerulonephritis and renal lesions in nonmalignant monoclonal IgM gammopathy. 61
26892336 2016
58
Treatment of chronic kidney disease using a traditional Chinese medicine, Flos Abelmoschus manihot (Linnaeus) Medicus (Malvaceae). 61
26667396 2016
59
Podocyte-Specific Deletion of Yes-Associated Protein Causes FSGS and Progressive Renal Failure. 61
26015453 2016
60
Immunosuppressive agents versus steroids in the treatment of IgA nephropathy-induced proteinuria: A meta-analysis. 61
26889216 2016
61
Primary glomerular disease in adults: pattern over decades,interpretation across the globe. 61
28197515 2016
62
Effect of Huai Qi Huang on Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells through miR-200a. 61
26884796 2016
63
FSGS: Diagnosis and Diagnostic Work-Up. 61
27314022 2016
64
Expression pattern of aquaporins in patients with primary nephrotic syndrome with edema. 61
26261083 2015
65
Spectrum of IgA nephropathy in a single center. 61
26354591 2015
66
Increasing frequency of idiopathic membranous nephropathy in primary glomerular disease: a 10-year renal biopsy study from a single Chinese nephrology centre. 61
26086701 2015
67
Primary glomerular diseases in the elderly. 61
25949940 2015
68
[In Process Citation]. 61
25722314 2015
69
Glucocorticoid pharmacogenetics in pediatric idiopathic nephrotic syndrome. 61
26419298 2015
70
IgA nephropathy in Brazil: apropos of 600 cases. 61
26435893 2015
71
Focal and segmental glomerulosclerosis: clinical and kidney biopsy correlations. 61
25503953 2014
72
Demographic and clinical characteristics of primary glomerular diseases in Turkey. 61
25269407 2014
73
The renal histopathology spectrum of elderly patients with kidney diseases: a study of 430 patients in a single Chinese center. 61
25526441 2014
74
Efficacy and safety of mycophenolate mofetil treatment in IgA nephropathy: a systematic review. 61
25475967 2014
75
Preliminary study of Huai Qi Huang granules delay the development of primary glomerular diseases in human. 61
25246341 2014
76
TLR9 and BAFF: their expression in patients with IgA nephropathy. 61
24993857 2014
77
A multinational phase IIb/III trial of beraprost sodium, an orally active prostacyclin analogue, in patients with primary glomerular disease or nephrosclerosis (CASSIOPEIR trial), rationale and study design. 61
25233856 2014
78
Efficacy and safety of Abelmoschus manihot for primary glomerular disease: a prospective, multicenter randomized controlled clinical trial. 61
24631042 2014
79
New insights into the pathogenesis of IgA nephropathy: do toll like receptor 9-B cell activation factor-IgA class switching recombination signaling axis induce IgA hyper-production? 61
24828398 2014
80
Post exertional hematuria. 61
24865509 2014
81
Glomerular disease: looking beyond pathology. 61
24700796 2014
82
Spectrum of biopsy-proven kidney disease in children at a Jordanian Hospital. 61
24821178 2014
83
B cell suppression in primary glomerular disease. 61
24602466 2014
84
[Rapidly progressive glomerulonephritis: a diagnostic and therapeutic emergency]. 61
24665657 2014
85
Comparison of characteristics of chronic kidney diseases between Tibet plateau and plain areas. 61
25337266 2014
86
C509T and T869C polymorphisms of transforming growth factor β1 and the risk of IgA nephropathy: a meta-analysis. 61
24286426 2013
87
Pattern of glomerular disease in the Saudi population: a single-center, five-year retrospective study. 61
24231502 2013
88
De novo expression of human leukocyte antigen-DR (HLA-DR) and loss of beta-catenin expression in tubular epithelial cells: a possible event in epithelial-mesenchymal transition in canine renal diseases. 61
23850018 2013
89
Recurrent proliferative glomerulonephritis with monoclonal IgG deposits of IgG2λ subtype in a transplanted kidney: a case report. 61
23474011 2013
90
Dent's disease: Identification of seven new pathogenic mutations in the CLCN5 gene. 61
27625851 2013
91
Resurgence of membranous nephropathy in African Americans in inner city Chicago. 61
27293563 2013
92
The spectrum of glomerular diseases on renal biopsy: data from a single tertiary center in oman. 61
23772291 2013
93
Histological pattern of primary glomerular diseases among adult Sudanese patients: A single center experience. 61
23814414 2013
94
Serum levels of cancer biomarkers in diabetic and non-diabetic proteinuric patients: a preliminary study. 61
23314541 2013
95
Pattern of glomerular diseases in Oman: a study based on light microscopy and immunofluorescence. 61
23538373 2013
96
Evaluation of anemia and serum iPTH, calcium, and phosphorus in patients with primary glomerulonephritis. 61
23689565 2013
97
Treatment of progressive IgA nephropathy: an update. 61
23689569 2013
98
Pattern of glomerular diseases in a tertiary care center in South India: a prospective study. 61
23354219 2013
99
Renal disease in the elderly and the very elderly Japanese: analysis of the Japan Renal Biopsy Registry (J-RBR). 61
23053590 2012
100
Infantile immunoglobulin A nephropathy showing features of membranoproliferative glomerulonephritis. 61
23089637 2012
101
Retinal involvement in nephrotic syndrome secondary to minimal change disease. 61
22562301 2012
102
Pattern of glomerular diseases among adults in Rajshahi, the Northern Region of Bangladesh. 61
22805414 2012
103
Percutaneous renal biopsy results: a retrospective analysis of 511 consecutive cases. 61
22569458 2012
104
The genetic variants at the HLA-DRB1 gene are associated with primary IgA nephropathy in Han Chinese. 61
22578019 2012
105
Tubular deficiency of von Hippel-Lindau attenuates renal disease progression in anti-GBM glomerulonephritis. 61
21925138 2011
106
Persistent asymptomatic isolated microscopic hematuria in Israeli adolescents and young adults and risk for end-stage renal disease. 61
21846854 2011
107
Renal biopsy and pathologic evaluation of glomerular disease. 61
21782145 2011
108
Frequency of primary glomerular disease in northeastern China. 61
21779635 2011
109
Registry of kidney biopsy in a single center in Puerto Rico: university district hospital. 61
23210326 2011
110
Impact of recurrent glomerulonephritis on renal graft survival. 61
21839228 2011
111
Clinical, histopathological and immunofluorescent findings of IgA nephropathy. 61
21705838 2011
112
Renal lesions of nondomestic felids. 61
20876911 2011
113
Fibrillary glomerulonephritis: a report of 66 cases from a single institution. 61
21441134 2011
114
The pathogenesis of IgA nephropathy. 61
21301336 2011
115
Non-immunosuppressive treatment for IgA nephropathy. 61
21412884 2011
116
Biophysical properties of normal and diseased renal glomeruli. 61
21123730 2011
117
Renal biopsy findings in Iran: case series report from a referral kidney center. 61
20052543 2010
118
Biopsy-diagnosed renal disease in patients after transplantation of other organs and tissues. 61
20883535 2010
119
Glomerular disease: why is there a dearth of high quality clinical trials? 61
20520593 2010
120
Histopathologic features aid in predicting risk for progression of IgA nephropathy. 61
20089495 2010
121
An overview on frequency of renal biopsy diagnosis in Brazil: clinical and pathological patterns based on 9,617 native kidney biopsies. 61
19633091 2010
122
Acute kidney injury in pediatric patients: experience of a single center during an 11-year period. 61
20966626 2010
123
The changing pattern of adult primary glomerular disease. 61
19487734 2009
124
Glomerular disease in the elderly. 61
19765489 2009
125
Discoveries have led to identifying a number of heritable and acquired primary glomerular disease. 61
19491675 2009
126
[Clinical and pathological analysis of 217 patients with IgA nephropathy from Hainan Province]. 61
19620078 2009
127
Childhood primary glomerular diseases in the western region of Saudi Arabia. 61
19587501 2009
128
Renal histological findings in adults in Jamaica. 61
20043536 2009
129
Study on the relationship between blood stasis syndrome and clinical pathology in 227 patients with primary glomerular disease. 61
19568708 2009
130
[Diabetic nephropathy and primary glomarular diseases]. 61
19642534 2009
131
Kidney biopsy in west of Iran: Complications and histopathological findings. 61
20368927 2009
132
The changing spectrum of primary glomerular diseases within 15 years: a survey of 3331 patients in a single Chinese centre. 61
18940885 2009
133
Deletion of CD151 results in a strain-dependent glomerular disease due to severe alterations of the glomerular basement membrane. 61
18787104 2008
134
The impact of sex in primary glomerulonephritis. 61
18182409 2008
135
Outcome of primary glomerular disease in pediatric renal transplantation: a single-center experience. 61
18261566 2008
136
Recurrent or de novo IgA nephropathy with crescent formation after renal transplantation. 61
18661411 2008
137
[Advances in primary glomerular disease in 2007]. 61
18847426 2008
138
Etiological profile of nephrotic syndrome in Kashmir. 61
20368913 2008
139
Infection and glomerulonephritis. 61
17846774 2007
140
COQ2 nephropathy: a newly described inherited mitochondriopathy with primary renal involvement. 61
17855635 2007
141
Early changes in gene expression that influence the course of primary glomerular disease. 61
17457373 2007
142
IgM nephropathy in adults: incidence and correlation with electron microscopic features. 61
17883120 2007
143
[Correlation analysis on blood stasis syndrome, clinical features and renal pathology in 174 patients with primary glomerular diseases]. 61
17633356 2007
144
Low-dose methylprednisolone pulse therapy in Chinese children with steroid resistant focal segmental glomerulosclerosis. 61
17532834 2007
145
Prolonged renal failure secondary to antithymocyte globulin treatment in severe aplastic anemia. 61
17426071 2007
146
[Clinicopathologic characteristics of 1,316 children with renal disease]. 61
17448305 2007
147
Interstitial nephritis secondary to bevacizumab treatment in metastatic leiomyosarcoma. 61
17374619 2007
148
Clinical study of plasma thrombomodulin detection. 61
17490534 2007
149
[Treatment of nephrotic syndrome in the adult]. 61
17256632 2006
150
ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome. 61
17056598 2006
151
Paulista Registry of glomerulonephritis: 5-year data report. 61
16968733 2006
152
An analysis of 3,555 cases of renal biopsy in Thailand. 61
17044461 2006
153
Mycophenolate mofetil treatment in primary glomerular disease: one-year follow-up in steroid dependent and resistant nephrotic syndrome. 61
17044475 2006
154
Renal diseases: a 27-year renal biopsy study. 61
17048208 2006
155
Focal segmental glomerulosclerosis associated with essential thrombocythemia. 61
16544181 2006
156
Characterization of kidney lesions in Indian adults: towards a renal biopsy registry. 61
16736422 2006
157
Acute renal failure secondary to imatinib mesylate treatment in prostate cancer. 61
16288076 2005
158
Proteinuria and hemoglobin levels in patients with primary glomerular disease. 61
16129203 2005
159
Immunotactoid glomerulopathy with microtubular deposits, with reference to the characteristics of Japanese cases. 61
15909596 2005
160
[Preliminary study on cytomegalovirus infection in children with primary glomerular disease]. 61
15833173 2005
161
[Membranous nephropathy and crescentic glomerulonephritis]. 61
16053015 2005
162
Twenty-one-year trend in ESRD due to focal segmental glomerulosclerosis in the United States. 61
15492947 2004
163
Renal biopsy findings in the kingdom of bahrain: a 13-year retrospective study. 61
17642789 2004
164
Signs and symptoms of thin basement membrane nephropathy: a prospective regional study on primary glomerular disease-The Limburg Renal Registry. 61
15327380 2004
165
The spectrum of glomerular diseases in the kingdom of bahrain: an epidemiological study based on renal biopsy interpretation. 61
15350479 2004
166
Glomerular expression of biglycan and decorin and urinary levels of decorin in primary glomerular disease. 61
14964452 2004
167
Self-performed peritoneal dialysis in prisoners. 61
15384805 2004
168
The incidence of biopsy-proven primary glomerulonephritis in the Republic of Macedonia-long-term follow-up. 61
12817063 2003
169
Targeted downregulation of extracellular nephrin in human IgA nephropathy. 61
12853730 2003
170
Renal function in proteinuric glomerular diseases correlates to the changes in urine IgM excretion but not to the changes in the degree of albuminuria. 61
12779096 2003
171
Idiopathic focal segmental glomerulosclerosis. 61
12704578 2003
172
Glomerular calcification in hypercalcemic nephropathy. 61
12562259 2003
173
Role of sequential biopsy study in the evaluation of renal transplant. 61
17657085 2003
174
Spectrum of glomerular disease in iraqi patients from a single center. 61
17660678 2002
175
Collapsing glomerulopathy: a cause of noncardiogenic pulmonary edema. 61
12200827 2002
176
Urinary type IV collagen: a specific indicator of incipient diabetic nephropathy. 61
11940372 2002
177
TGF-beta1-induced glomerular disorder is associated with impaired concentrating ability mimicking primary glomerular disease with renal failure in man. 61
11140698 2000
178
Renal sarcoidosis with superimposed postinfectious glomerulonephritis presenting as acute renal failure. 61
10873903 2000
179
Prevalence of glomerular diseases: king khalid university hospital, saudi arabia. 61
18209337 2000
180
Vascular hyperpermeability in nephrotic edema. 61
10867533 2000
181
Chronic proteinuric nephropathies: outcomes and response to treatment in a prospective cohort of 352 patients with different patterns of renal injury. 61
10845831 2000
182
SPECTRUM OF NEPHROPATHIES WITH SPECIAL REFERENCE TO PRIMARY GLOMERULOPATHIES. 61
28790675 2000
183
Long-term follow-up study of IgM associated nephrotic syndrome patients: clinical outcome and prognostic indicators. 61
10808687 2000
184
Immunohistochemical evidence for an increased oxidative stress and carbonyl modification of proteins in diabetic glomerular lesions. 61
10203367 1999
185
Pattern of renal diseases among adults in Saudi Arabia: a clinicopathologic study. 61
10600069 1999
186
Analysis of 490 kidney biopsies: data from the United Arab Emirates Renal Diseases Registry. 61
9650123 1998
187
Increased atherogenicity of low-density lipoprotein in heavy proteinuria. 61
9623551 1998
188
The importance of tubulointerstitial injury in the early phase of primary glomerular disease. 61
9627159 1998
189
Treatment of severe nephrotic syndrome. 61
9475489 1998
190
Decreased excretion of urine glycosaminoglycans as marker in renal amyloidosis. 61
9198045 1997
191
Fas antigen expression and its relationship with apoptosis in transplanted kidney. 61
9103214 1997
192
Myofibroblast and alpha 1 (III) collagen expression in experimental tubulointerstitial nephritis. 61
9067932 1997
193
[Clinical significance of plasma alpha-granule membrane protein-140 in blood stasis of primary glomerular disease]. 61
9387762 1996
194
Pattern of glomerular disease in Saudi Arabia. 61
8651243 1996
195
Expression of genes that promote renal interstitial fibrosis in rats with proteinuria. 61
8731195 1996
196
The pattern of glomerular disease in New Caledonia: preliminary findings. 61
8714267 1996
197
Prevalence of adult primary glomerular diseases: retrospective analysis of 206 kidney biopsies (1990-1993). 61
8762646 1996
198
CD45RO and CD45RA positive cell populations in idiopathic membranous and IgA glomerulopathy. 61
8666684 1996
199
Proteinuria: a risk factor for pregnancy-related renal function decline in primary glomerular disease? 61
7611251 1995
200
Hepatitis C virus-associated glomerulonephritis. Effect of alpha-interferon therapy. 61
7535369 1994
201
[A clinical study of renal hemodynamics in patients with lupus nephritis]. 61
7974023 1994
202
The relationship between urinary albumin excretion rate and serum cholesterol in primary glomerular disease. 61
8187354 1994
203
Plasma thrombomodulin in primary glomerular disease and lupus glomerulonephritis. 61
8072607 1994
204
Renal failure due to mesangiocapillary glomerulonephritis in pregnancy: use of plasma exchange therapy. 61
8222375 1993
205
Increased mRNA expression encoding for medullasin in peripheral blood mononuclear cells from patients with IgA nephropathy. 61
8491047 1993
206
Renal amyloidosis and other fibrillar glomerular diseases. 61
7922183 1993
207
Epidemiology of primary glomerular disease in the elderly. A prospective study during a 15-year period. 61
8252865 1993
208
Urinary dopamine excretion in chronic renal disease. 61
1489161 1992
209
Urinary excretion of beta 2-glycoprotein-1 (apolipoprotein H) and other markers of tubular malfunction in "non-tubular" renal disease. 61
1381383 1992
210
Effect of simvastatin on plasma lipid and lipoprotein concentrations and low-density lipoprotein metabolism in the nephrotic syndrome. 61
1320552 1992
211
Urolithiasis in patients with end stage renal failure. 61
1552617 1992
212
Immunopathological aspects of immunoglobulin A nephropathy and other mesangial proliferative glomerulonephritides. 61
1600132 1992
213
Coagulation and fibrinolysis in patients with chronic renal failure undergoing conservative treatment. 61
1776141 1991
214
Abnormal glomerular and tubular response to intravenous frusemide in patients with chronic glomerulonephritis. 61
1922908 1991
215
Effects of atrial natriuretic peptide on urinary protein excretion in mesangial proliferative glomerulonephritis. 61
1830375 1991
216
Thin basement membrane nephropathy as a cause of recurrent haematuria in childhood. 61
2361650 1990
217
[Fetal and maternal risk of pregnancy in women with primary chronic glomerulonephritis]. 61
2202924 1990
218
Primary IgA nephropathies in children. 61
2397277 1990
219
Antiproteinuric effect of angiotensin-converting-enzyme inhibitors in patients with primary glomerular disease and normal renal function. 61
2129469 1990
220
Protein-restricted diets in chronic renal failure: a four year follow-up shows limited indications. 61
2636680 1989
221
Role of iron in the tubulo-interstitial injury in nephrotoxic serum nephritis. 61
2615188 1989
222
[Aberrant expression of major histocompatibility complex class II. (HLA-DR/DQ) antigens and proliferative nuclear antigen. (Ki-67) in renal tubular epithelial cells]. 61
2625737 1989
223
Dietary protein restriction in chronic renal failure: an update. 61
2681967 1989
224
Focal segmental glomerulosclerosis. A common entity in nephrotic black adults. 61
2764652 1989
225
[Epidemiology of glomerular diseases in a region in France. Changes as a function of periods and the age of patients]. 61
2974577 1988
226
Platelet adenine nucleotides in patients with primary glomerular disease. 61
3252552 1988
227
Histologic studies on the nephrotic syndrome in the elderly. 61
3433283 1987
228
Antiproteinuric effect of captopril in primary glomerular disease. 61
3299120 1987
229
Successful pregnancy in primary glomerular disease. 61
3820941 1986
230
The natural history of membranous nephropathy in the West of Scotland. 61
3774962 1986
231
Use of beta 2 microglobulin to diagnose tubulo-interstitial renal lesions in children. 61
3528618 1986
232
Serum and urinary high density lipoproteins in glomerular disease with proteinuria. 61
3091902 1986
233
Does pregnancy aggravate primary glomerular disease? 61
4050786 1985
234
Pregnancy does not exacerbate primary glomerular disease. 61
4050788 1985
235
Clinical studies on primary glomerular disease. 61
6387234 1984
236
Clinical and immunopathologic study of mesangial IgM nephropathy: report of 41 cases. 61
6376323 1984
237
Proteinuria and glomerular disease in Jamaica. 61
6733987 1984
238
Acute glomerulonephritis. A clinical overview. 61
6369024 1984
239
Immune reactivity and immunosuppressive intervention in experimental nephritis. II. Effect of TLI on the course of two models of nephritis in the inbred rat. 61
6228585 1984
240
[In vitro production of a human lymphokine by a specific mitogen in primary glomerular nephropathies]. 61
6476490 1984
241
[Primary glomerular disease--immunopathological studies and therapy]. 61
6373978 1983
242
[Glomerulopathies in the aged (excluding diabetes)]. 61
6316541 1983
243
Association of hepatitis B surface (HBs) antigenemia and membranous nephropathy in children in Taiwan. 61
6354538 1983
244
An overlapping syndrome of IgA nephropathy and membranous nephropathy? 61
6350913 1983
245
Suppressor cell function in patients with primary glomerular disease. 61
6213336 1982
246
Primary glomerular disease: to treat or not to treat. 61
7116871 1982
247
Gastrointestinal protein loss in the nephrotic syndrome studied with 51Cr-albumin. 61
7383234 1980
248
Proteinuria in congenital nephrotic syndrome of the Finnish type. 61
6988118 1980
249
[Clinical significance of fibrin/fibrinogen degradation products in primary glomerular disease (author's transl)]. 61
671857 1978
250
Bone mineral status measured by direct photon absorptiometry in childhood renal disease. 61
600598 1977
251
IgA nephropathy: a syndrome of uniform morphology, diverse clinical features and uncertain prognosis. 61
589877 1977
252
[Primary glomerular disease associated with inhaled organic solvants (author's transl)]. 61
607174 1977
253
[Serum immunoglobulins in primary glomerular disease (author's transl)]. 61
916249 1977
254
Cytotoxic drugs in primary glomerular disease. 61
4468427 1974
255
Primary glomerular disease with extraglomerular vascular osmiophilic deposits. 61
4114494 1972

Variations for Primary Glomerular Disease

Expression for Primary Glomerular Disease

Search GEO for disease gene expression data for Primary Glomerular Disease.

Pathways for Primary Glomerular Disease

GO Terms for Primary Glomerular Disease

Cellular components related to Primary Glomerular Disease according to GeneCards Suite gene sharing:

(showing 6, show less)
# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.56 TGFB1 SERPINE1 DCN ALB
2 extracellular space GO:0005615 9.46 TGFB1 SERPINE1 DCN ALB
3 blood microparticle GO:0072562 9.37 TGFB1 ALB
4 Golgi lumen GO:0005796 9.32 TGFB1 DCN
5 collagen-containing extracellular matrix GO:0062023 9.13 TGFB1 SERPINE1 DCN
6 platelet alpha granule lumen GO:0031093 8.8 TGFB1 SERPINE1 ALB

Biological processes related to Primary Glomerular Disease according to GeneCards Suite gene sharing:

(showing 2, show less)
# Name GO ID Score Top Affiliating Genes
1 wound healing GO:0042060 8.96 TGFB1 DCN
2 platelet degranulation GO:0002576 8.8 TGFB1 SERPINE1 ALB

Molecular functions related to Primary Glomerular Disease according to GeneCards Suite gene sharing:

(showing 1, show less)
# Name GO ID Score Top Affiliating Genes
1 protein N-terminus binding GO:0047485 8.62 TGFB1 DCN

Sources for Primary Glomerular Disease

3 CDC
7 CNVD
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10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
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30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
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35 IUPHAR
36 KEGG
37 LifeMap
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68 SNOMED-CT via HPO
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70 Tocris
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72 UMLS via Orphanet
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