MCID: PRM247
MIFTS: 16

Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine Viral Infection

Categories: Blood diseases, Immune diseases, Infectious diseases, Rare diseases

Aliases & Classifications for Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine...

MalaCards integrated aliases for Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine Viral Infection:

Name: Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine Viral Infection 58
Primary Immunodeficiency with Post-Mmr Vaccine Viral Infection 58

Characteristics:

Orphanet epidemiological data:

58
primary immunodeficiency with post-measles-mumps-rubella vaccine viral infection
Inheritance: Autosomal recessive; Prevalence: <1/1000000 (Worldwide); Age of onset: Infancy;

Classifications:

Orphanet: 58  
Rare immunological diseases


External Ids:

ICD10 via Orphanet 33 D84.8
Orphanet 58 ORPHA431166

Summaries for Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine...

MalaCards based summary : Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine Viral Infection, also known as primary immunodeficiency with post-mmr vaccine viral infection, is related to measles and mumps. An important gene associated with Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine Viral Infection is STAT2 (Signal Transducer And Activator Of Transcription 2), and among its related pathways/superpathways are Toll-like Receptor Signaling Pathway and PI3K-Akt signaling pathway.

Related Diseases for Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine...

Diseases related to Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine Viral Infection via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 measles 9.5 STAT2 IFNAR2
2 mumps 9.5 STAT2 IFNAR2
3 microphthalmia with limb anomalies 9.4 STAT2 IFNAR2
4 viral infectious disease 9.2 STAT2 IFNAR2

Symptoms & Phenotypes for Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine...

Drugs & Therapeutics for Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine...

Search Clinical Trials , NIH Clinical Center for Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine Viral Infection

Genetic Tests for Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine...

Anatomical Context for Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine...

Publications for Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine...

Articles related to Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine Viral Infection:

# Title Authors PMID Year
1
Signal transducer and activator of transcription 2 deficiency is a novel disorder of mitochondrial fission. 6
26122121 2015
2
STAT2 deficiency and susceptibility to viral illness in humans. 6
23391734 2013

Variations for Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine...

Expression for Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine...

Search GEO for disease gene expression data for Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine Viral Infection.

Pathways for Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine...

Pathways related to Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine Viral Infection according to GeneCards Suite gene sharing:

(show all 16)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.49 STAT2 IFNAR2
2
Show member pathways
12.38 STAT2 IFNAR2
3
Show member pathways
12.33 STAT2 IFNAR2
4 12.25 STAT2 IFNAR2
5
Show member pathways
12.22 STAT2 IFNAR2
6 12.19 STAT2 IFNAR2
7
Show member pathways
11.95 STAT2 IFNAR2
8
Show member pathways
11.74 STAT2 IFNAR2
9
Show member pathways
11.69 STAT2 IFNAR2
10
Show member pathways
11.69 STAT2 IFNAR2
11 11.66 STAT2 IFNAR2
12
Show member pathways
11.61 STAT2 IFNAR2
13 11.26 STAT2 IFNAR2
14 11.2 STAT2 IFNAR2
15 10.7 STAT2 IFNAR2
16
Show member pathways
9.98 STAT2 IFNAR2

GO Terms for Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine...

Biological processes related to Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine Viral Infection according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.26 STAT2 IFNAR2
2 defense response to virus GO:0051607 9.16 STAT2 IFNAR2
3 type I interferon signaling pathway GO:0060337 8.96 STAT2 IFNAR2
4 JAK-STAT cascade GO:0007259 8.62 STAT2 IFNAR2

Sources for Primary Immunodeficiency with Post-Measles-Mumps-Rubella Vaccine...

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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