MCID: PRM139
MIFTS: 12

Primary Melanoma of the Central Nervous System

Categories: Neuronal diseases, Rare diseases, Skin diseases

Aliases & Classifications for Primary Melanoma of the Central Nervous System

MalaCards integrated aliases for Primary Melanoma of the Central Nervous System:

Name: Primary Melanoma of the Central Nervous System 54 60
Primary Melanoma of the Cns 54 60
Primary Leptomeningeal Malignant Melanoma 74
Malignant Melanoma of Meninges 60
Primary Meningeal Melanoma 54
Primary Cns Melanoma 54

Classifications:

Orphanet: 60  
Rare neurological diseases


External Ids:

Orphanet 60 ORPHA252050
UMLS 74 C2026298

Summaries for Primary Melanoma of the Central Nervous System

NIH Rare Diseases : 54 The following summary is from Orphanet, a European reference portal for information on rare diseases and orphan drugs.Orpha Number: 252050Disease definitionPrimary melanoma of the central nervous system is a rare tumor of meninges arising from leptomeningeal melanocytes, typically in the perimedullary or high cervical region, in the absence of melanoma outside the CNS. The tumor is typically a darkly pigmented, solid mass, often containing hemorrhagic or necrotic areas, composed of sheets of pleomorphic cells with prominent nucleoli, with frequent mitotic figures and parenchymal invasion. Intracranial tumor may present with signs of raised intracranial pressure, focal neurological symptoms related to tumor location, seizures or subarachnoid hemorrhage, spinal tumor may present with back pain, muscle weakness, numbness, plegia or urinary incontinence.Visit the Orphanet disease page for more resources.

MalaCards based summary : Primary Melanoma of the Central Nervous System, also known as primary melanoma of the cns, is related to meningeal melanoma and melanoma. Affiliated tissues include skin.

Related Diseases for Primary Melanoma of the Central Nervous System

Diseases related to Primary Melanoma of the Central Nervous System via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 meningeal melanoma 10.1
2 melanoma 9.9
3 neurofibromatosis, type iv, of riccardi 9.8
4 melanosis, neurocutaneous 9.8

Symptoms & Phenotypes for Primary Melanoma of the Central Nervous System

Drugs & Therapeutics for Primary Melanoma of the Central Nervous System

Search Clinical Trials , NIH Clinical Center for Primary Melanoma of the Central Nervous System

Genetic Tests for Primary Melanoma of the Central Nervous System

Anatomical Context for Primary Melanoma of the Central Nervous System

MalaCards organs/tissues related to Primary Melanoma of the Central Nervous System:

42
Skin

Publications for Primary Melanoma of the Central Nervous System

Articles related to Primary Melanoma of the Central Nervous System:

# Title Authors Year
1
Primary melanoma of the CNS in children is driven by congenital expression of oncogenic NRAS in melanocytes. ( 23303902 )
2013

Variations for Primary Melanoma of the Central Nervous System

Expression for Primary Melanoma of the Central Nervous System

Search GEO for disease gene expression data for Primary Melanoma of the Central Nervous System.

Pathways for Primary Melanoma of the Central Nervous System

GO Terms for Primary Melanoma of the Central Nervous System

Sources for Primary Melanoma of the Central Nervous System

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....