MCID: PRM284
MIFTS: 26

Primitive Neuroectodermal Tumor of the Cervix Uteri

Categories: Cancer diseases, Neuronal diseases, Rare diseases, Reproductive diseases

Aliases & Classifications for Primitive Neuroectodermal Tumor of the Cervix Uteri

MalaCards integrated aliases for Primitive Neuroectodermal Tumor of the Cervix Uteri:

Name: Primitive Neuroectodermal Tumor of the Cervix Uteri 58
Malignant Peripheral Neuroectodermal Tumor of the Cervix Uteri 58
Cervical Malignant Peripheral Neuroectodermal Tumor 58
Peripheral Neuroectodermal Cancer of Cervix Uteri 58
Cervical Peripheral Neuroectodermal Cancer 58

Classifications:

Orphanet: 58  
Rare gynaecological and obstetric diseases


External Ids:

ICD10 via Orphanet 33 C53.0 C53.1 C53.8
Orphanet 58 ORPHA213812

Summaries for Primitive Neuroectodermal Tumor of the Cervix Uteri

MalaCards based summary : Primitive Neuroectodermal Tumor of the Cervix Uteri, also known as malignant peripheral neuroectodermal tumor of the cervix uteri, is related to infantile digital fibromatosis and fibroma. An important gene associated with Primitive Neuroectodermal Tumor of the Cervix Uteri is DES (Desmin), and among its related pathways/superpathways are Spinal Cord Injury and Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include cervix, brain and pineal, and related phenotype is cellular.

Related Diseases for Primitive Neuroectodermal Tumor of the Cervix Uteri

Diseases related to Primitive Neuroectodermal Tumor of the Cervix Uteri via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 162)
# Related Disease Score Top Affiliating Genes
1 infantile digital fibromatosis 10.1 VIM DES
2 fibroma 10.1 VIM DES
3 fibromatosis 10.1 VIM DES
4 lymphangiomatosis 10.1 VIM DES
5 spindle cell thymoma 10.1 ENO2 DES
6 benign metastasizing leiomyoma 10.1 VIM DES
7 leiomyoma 10.1 VIM DES
8 ectomesenchymoma 10.1 ENO2 DES
9 angiolipoma 10.1 VIM DES
10 glomangioma 10.1 VIM DES
11 spindle cell lipoma 10.1 VIM DES
12 embryonal sarcoma 10.1 VIM DES
13 biphasic synovial sarcoma 10.1 VIM DES
14 chondromyxoid fibroma 10.1 VIM DES
15 ovarian small cell carcinoma 10.1 ENO2 DES
16 bednar tumor 10.1 VIM ENO2
17 congenital fibrosarcoma 10.1 VIM DES
18 papillary tumor of the pineal region 10.1 VIM ENO2
19 pleomorphic liposarcoma 10.1 VIM DES
20 liposarcoma 10.1 VIM DES
21 ewing sarcoma of bone 10.1 VIM ENO2
22 adenosarcoma 10.1 VIM DES
23 sarcomatoid mesothelioma 10.1 VIM DES
24 gliomatosis peritonei 10.1 GFAP DES
25 perivascular epithelioid cell tumor 10.1 VIM DES
26 pseudosarcomatous fibromatosis 10.1 VIM DES
27 cutaneous fibrous histiocytoma 10.1 VIM DES
28 nephroma 10.1 VIM DES
29 infantile myofibromatosis 10.1 VIM DES
30 granulosa cell tumor of the ovary 10.1 VIM ENO2
31 medullomyoblastoma 10.1 GFAP DES
32 syringocystadenoma papilliferum 10.1 GFAP DES
33 smooth muscle tumor 10.1 VIM DES
34 cavernous hemangioma 10.1 VIM DES
35 spindle cell sarcoma 10.0 VIM DES
36 spindle cell rhabdomyosarcoma 10.0 GFAP DES
37 intracranial cysts 10.0 GFAP ENO2
38 angiomyolipoma 10.0 VIM DES
39 cerebral neuroblastoma 10.0 GFAP ENO2
40 subependymoma 10.0 GFAP ENO2
41 angiocentric glioma 10.0 VIM GFAP
42 pineocytoma 10.0 GFAP ENO2
43 spinal cord oligodendroglioma 10.0 GFAP ENO2
44 endobronchial leiomyoma 10.0 GFAP ENO2
45 sertoli cell tumor 10.0 VIM ENO2
46 muscle cancer 10.0 ENO2 DES
47 chordoid meningioma 10.0 VIM GFAP
48 anaplastic ependymoma 10.0 VIM GFAP
49 cerebrovascular benign neoplasm 10.0 GFAP ENO2
50 cerebellum cancer 10.0 GFAP ENO2

Graphical network of the top 20 diseases related to Primitive Neuroectodermal Tumor of the Cervix Uteri:



Diseases related to Primitive Neuroectodermal Tumor of the Cervix Uteri

Symptoms & Phenotypes for Primitive Neuroectodermal Tumor of the Cervix Uteri

MGI Mouse Phenotypes related to Primitive Neuroectodermal Tumor of the Cervix Uteri:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.02 DES ENO2 GFAP PTPRC VIM

Drugs & Therapeutics for Primitive Neuroectodermal Tumor of the Cervix Uteri

Search Clinical Trials , NIH Clinical Center for Primitive Neuroectodermal Tumor of the Cervix Uteri

Genetic Tests for Primitive Neuroectodermal Tumor of the Cervix Uteri

Anatomical Context for Primitive Neuroectodermal Tumor of the Cervix Uteri

MalaCards organs/tissues related to Primitive Neuroectodermal Tumor of the Cervix Uteri:

40
Cervix, Brain, Pineal, Bone, Cerebellum, Spinal Cord, Heart

Publications for Primitive Neuroectodermal Tumor of the Cervix Uteri

Articles related to Primitive Neuroectodermal Tumor of the Cervix Uteri:

# Title Authors PMID Year
1
Primitive neuroectodermal tumor of the cervix: a case report. 61
21962148 2011
2
Primitive neuroectodermal tumor of the cervix uteri: a case report -- changing concepts in therapy. 61
15979131 2005
3
Primitive neuroectodermal tumor of the cervix uteri. A case report. 61
9065588 1997

Variations for Primitive Neuroectodermal Tumor of the Cervix Uteri

Expression for Primitive Neuroectodermal Tumor of the Cervix Uteri

Search GEO for disease gene expression data for Primitive Neuroectodermal Tumor of the Cervix Uteri.

Pathways for Primitive Neuroectodermal Tumor of the Cervix Uteri

Pathways related to Primitive Neuroectodermal Tumor of the Cervix Uteri according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.48 VIM GFAP
2 11.35 PTPRC DES
3 11.15 VIM GFAP
4 11.01 VIM DES
5
Show member pathways
10.83 VIM GFAP DES
6
Show member pathways
10.61 VIM DES
7 10.4 VIM GFAP DES

GO Terms for Primitive Neuroectodermal Tumor of the Cervix Uteri

Cellular components related to Primitive Neuroectodermal Tumor of the Cervix Uteri according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament GO:0005882 9.13 VIM GFAP DES
2 intermediate filament cytoskeleton GO:0045111 8.8 VIM GFAP DES

Biological processes related to Primitive Neuroectodermal Tumor of the Cervix Uteri according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of neuron projection development GO:0010977 9.37 VIM GFAP
2 muscle filament sliding GO:0030049 9.32 VIM DES
3 astrocyte development GO:0014002 9.26 VIM GFAP
4 Bergmann glial cell differentiation GO:0060020 9.16 VIM GFAP
5 intermediate filament-based process GO:0045103 8.96 VIM GFAP
6 intermediate filament organization GO:0045109 8.8 VIM GFAP DES

Molecular functions related to Primitive Neuroectodermal Tumor of the Cervix Uteri according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.8 VIM GFAP DES

Sources for Primitive Neuroectodermal Tumor of the Cervix Uteri

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
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41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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