MCID: PRM284
MIFTS: 27

Primitive Neuroectodermal Tumor of the Cervix Uteri

Categories: Reproductive diseases, Rare diseases, Neuronal diseases, Cancer diseases

Aliases & Classifications for Primitive Neuroectodermal Tumor of the Cervix Uteri

MalaCards integrated aliases for Primitive Neuroectodermal Tumor of the Cervix Uteri:

Name: Primitive Neuroectodermal Tumor of the Cervix Uteri 59
Malignant Peripheral Neuroectodermal Tumor of the Cervix Uteri 59
Cervical Malignant Peripheral Neuroectodermal Tumor 59
Peripheral Neuroectodermal Cancer of Cervix Uteri 59
Cervical Peripheral Neuroectodermal Cancer 59

Classifications:



External Ids:

Orphanet 59 ORPHA213812
ICD10 via Orphanet 34 C53.0 C53.1 C53.8

Summaries for Primitive Neuroectodermal Tumor of the Cervix Uteri

MalaCards based summary : Primitive Neuroectodermal Tumor of the Cervix Uteri, also known as malignant peripheral neuroectodermal tumor of the cervix uteri, is related to infantile digital fibromatosis and lymphangiomatosis. An important gene associated with Primitive Neuroectodermal Tumor of the Cervix Uteri is DES (Desmin), and among its related pathways/superpathways are Spinal Cord Injury and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include cervix, and related phenotype is cellular.

Related Diseases for Primitive Neuroectodermal Tumor of the Cervix Uteri

Diseases related to Primitive Neuroectodermal Tumor of the Cervix Uteri via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 135)
# Related Disease Score Top Affiliating Genes
1 infantile digital fibromatosis 10.4 DES VIM
2 lymphangiomatosis 10.4 DES VIM
3 breast rhabdomyosarcoma 10.4 DES ENO2
4 angiolipoma 10.4 DES VIM
5 malignant ectomesenchymoma 10.4 DES ENO2
6 ectomesenchymoma 10.4 DES ENO2
7 spindle cell lipoma 10.4 DES VIM
8 benign metastasizing leiomyoma 10.4 DES VIM
9 biphasic synovial sarcoma 10.4 DES VIM
10 congenital fibrosarcoma 10.4 DES VIM
11 juvenile xanthogranuloma 10.3 DES VIM
12 pleomorphic liposarcoma 10.3 DES VIM
13 perivascular epithelioid cell tumor 10.3 DES VIM
14 cutaneous fibrous histiocytoma 10.3 DES VIM
15 mesenchymal chondrosarcoma 10.3 DES VIM
16 bednar tumor 10.3 ENO2 VIM
17 spindle cell sarcoma 10.3 DES VIM
18 pseudosarcomatous fibromatosis 10.3 DES VIM
19 papillary tumor of the pineal region 10.3 ENO2 VIM
20 ewing's family of tumors 10.3
21 embryonal sarcoma 10.3 DES VIM
22 smooth muscle tumor 10.3 DES VIM
23 gliomatosis peritonei 10.3 DES GFAP
24 hemangiopericytoma, malignant 10.3 DES VIM
25 cutaneous leiomyosarcoma 10.3 DES GFAP
26 spindle cell rhabdomyosarcoma 10.3 DES GFAP
27 infantile myofibromatosis 10.2 DES VIM
28 chondroid chordoma 10.2 ENO2 VIM
29 chondromyxoid fibroma 10.2 DES VIM
30 fasciitis 10.2 DES VIM
31 fibromatosis 10.2 DES VIM
32 intracranial cysts 10.2 ENO2 GFAP
33 cerebral primitive neuroectodermal tumor 10.2 ENO2 VIM
34 melanotic medulloblastoma 10.2 ENO2 GFAP
35 liver angiosarcoma 10.2 ENO2 VIM
36 cerebellar medulloblastoma 10.2 ENO2 GFAP
37 rhabdoid meningioma 10.2 GFAP VIM
38 muscle cancer 10.2 DES ENO2
39 central nervous system primitive neuroectodermal neoplasm 10.2 ENO2 GFAP
40 chordoid meningioma 10.2 GFAP VIM
41 subependymal glioma 10.2 ENO2 GFAP
42 cerebral neuroblastoma 10.2 ENO2 GFAP
43 granulosa cell tumor of the ovary 10.2 ENO2 VIM
44 benign ependymoma 10.2 ENO2 GFAP
45 ependymoblastoma 10.2 GFAP VIM
46 plexiform schwannoma 10.2 ENO2 GFAP
47 myxopapillary ependymoma 10.2 GFAP VIM
48 cerebral ventricle cancer 10.2 ENO2 GFAP
49 cerebrum cancer 10.2 ENO2 GFAP
50 pineal gland cancer 10.2 ENO2 GFAP

Graphical network of the top 20 diseases related to Primitive Neuroectodermal Tumor of the Cervix Uteri:



Diseases related to Primitive Neuroectodermal Tumor of the Cervix Uteri

Symptoms & Phenotypes for Primitive Neuroectodermal Tumor of the Cervix Uteri

MGI Mouse Phenotypes related to Primitive Neuroectodermal Tumor of the Cervix Uteri:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.02 DES ENO2 GFAP PTPRC VIM

Drugs & Therapeutics for Primitive Neuroectodermal Tumor of the Cervix Uteri

Search Clinical Trials , NIH Clinical Center for Primitive Neuroectodermal Tumor of the Cervix Uteri

Genetic Tests for Primitive Neuroectodermal Tumor of the Cervix Uteri

Anatomical Context for Primitive Neuroectodermal Tumor of the Cervix Uteri

MalaCards organs/tissues related to Primitive Neuroectodermal Tumor of the Cervix Uteri:

41
Cervix

Publications for Primitive Neuroectodermal Tumor of the Cervix Uteri

Articles related to Primitive Neuroectodermal Tumor of the Cervix Uteri:

# Title Authors Year
1
Primitive neuroectodermal tumor of the cervix uteri: a case report -- changing concepts in therapy. ( 15979131 )
2005
2
Primitive neuroectodermal tumor of the cervix uteri. A case report. ( 9065588 )
1997

Variations for Primitive Neuroectodermal Tumor of the Cervix Uteri

Expression for Primitive Neuroectodermal Tumor of the Cervix Uteri

Search GEO for disease gene expression data for Primitive Neuroectodermal Tumor of the Cervix Uteri.

Pathways for Primitive Neuroectodermal Tumor of the Cervix Uteri

Pathways related to Primitive Neuroectodermal Tumor of the Cervix Uteri according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.4 GFAP VIM
2 11.15 GFAP VIM
3 11.01 DES VIM
4
Show member pathways
10.83 DES GFAP VIM
5
Show member pathways
10.61 DES VIM

GO Terms for Primitive Neuroectodermal Tumor of the Cervix Uteri

Cellular components related to Primitive Neuroectodermal Tumor of the Cervix Uteri according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament cytoskeleton GO:0045111 8.96 DES GFAP
2 intermediate filament GO:0005882 8.8 DES GFAP VIM

Biological processes related to Primitive Neuroectodermal Tumor of the Cervix Uteri according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of neuron projection development GO:0010977 9.37 GFAP VIM
2 muscle filament sliding GO:0030049 9.32 DES VIM
3 astrocyte development GO:0014002 9.26 GFAP VIM
4 Bergmann glial cell differentiation GO:0060020 9.16 GFAP VIM
5 intermediate filament-based process GO:0045103 8.96 GFAP VIM
6 intermediate filament organization GO:0045109 8.8 DES GFAP VIM

Molecular functions related to Primitive Neuroectodermal Tumor of the Cervix Uteri according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.26 DES GFAP PTPRC VIM
2 structural constituent of cytoskeleton GO:0005200 8.8 DES GFAP VIM

Sources for Primitive Neuroectodermal Tumor of the Cervix Uteri

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