MCID: PRM284
MIFTS: 30

Primitive Neuroectodermal Tumor of the Cervix Uteri

Categories: Cancer diseases, Neuronal diseases, Rare diseases, Reproductive diseases

Aliases & Classifications for Primitive Neuroectodermal Tumor of the Cervix Uteri

MalaCards integrated aliases for Primitive Neuroectodermal Tumor of the Cervix Uteri:

Name: Primitive Neuroectodermal Tumor of the Cervix Uteri 59
Malignant Peripheral Neuroectodermal Tumor of the Cervix Uteri 59
Cervical Malignant Peripheral Neuroectodermal Tumor 59
Peripheral Neuroectodermal Cancer of Cervix Uteri 59
Cervical Peripheral Neuroectodermal Cancer 59

Classifications:



External Ids:

Orphanet 59 ORPHA213812
ICD10 via Orphanet 34 C53.0 C53.1 C53.8

Summaries for Primitive Neuroectodermal Tumor of the Cervix Uteri

MalaCards based summary : Primitive Neuroectodermal Tumor of the Cervix Uteri, also known as malignant peripheral neuroectodermal tumor of the cervix uteri, is related to ewing's family of tumors and malignant ectomesenchymoma. An important gene associated with Primitive Neuroectodermal Tumor of the Cervix Uteri is ENO2 (Enolase 2), and among its related pathways/superpathways are Spinal Cord Injury and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include cervix, brain and kidney, and related phenotype is cellular.

Related Diseases for Primitive Neuroectodermal Tumor of the Cervix Uteri

Diseases related to Primitive Neuroectodermal Tumor of the Cervix Uteri via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 143)
# Related Disease Score Top Affiliating Genes
1 ewing's family of tumors 10.4
2 malignant ectomesenchymoma 10.1 DES ENO2
3 ectomesenchymoma 10.1 DES ENO2
4 conventional fibrosarcoma 10.1 ENO2 PTPRC
5 kidney rhabdoid cancer 10.1 ENO2 PTPRC
6 endometrial small cell carcinoma 10.1 ENO2 PTPRC
7 small cell carcinoma 10.1 ENO2 PTPRC
8 gastric small cell carcinoma 10.1 ENO2 PTPRC
9 bone ewing's sarcoma 10.1 ENO2 PTPRC
10 intracranial cysts 10.1 ENO2 GFAP
11 melanotic medulloblastoma 10.1 ENO2 GFAP
12 cloacogenic carcinoma 10.1 ENO2 PTPRC
13 cerebellar medulloblastoma 10.1 ENO2 GFAP
14 central nervous system primitive neuroectodermal neoplasm 10.1 ENO2 GFAP
15 plexiform schwannoma 10.1 ENO2 GFAP
16 cerebral neuroblastoma 10.1 ENO2 GFAP
17 subependymal glioma 10.1 ENO2 GFAP
18 papillary ependymoma 10.1 ENO2 GFAP
19 cerebral ventricle cancer 10.1 ENO2 GFAP
20 microcystic meningioma 10.1 ENO2 GFAP
21 plasmablastic lymphoma 10.1 DES PTPRC
22 pineal gland cancer 10.1 ENO2 GFAP
23 olfactory neuroblastoma 10.1 ENO2 PTPRC
24 benign ependymoma 10.1 ENO2 GFAP
25 pineocytoma 10.1 ENO2 GFAP
26 subependymoma 10.1 ENO2 GFAP
27 gliomatosis peritonei 10.1 DES GFAP
28 benign glioma 10.1 ENO2 GFAP
29 central neurocytoma 10.1 ENO2 GFAP
30 cystic teratoma 10.1 ENO2 GFAP
31 teratoma 10.1 ENO2 GFAP
32 spindle cell rhabdomyosarcoma 10.1 DES GFAP
33 subependymal giant cell astrocytoma 10.1 ENO2 GFAP
34 central nervous system benign neoplasm 10.1 ENO2 GFAP
35 nervous system benign neoplasm 10.1 ENO2 GFAP
36 muscle cancer 10.0 DES ENO2
37 cerebellar liponeurocytoma 10.0 ENO2 GFAP
38 traumatic brain injury 10.0 ENO2 GFAP
39 trigeminal nerve neoplasm 10.0 GFAP PTPRC
40 neurilemmoma of the fifth cranial nerve 10.0 GFAP PTPRC
41 brain injury 10.0 ENO2 GFAP
42 juvenile pilocytic astrocytoma 10.0 ENO2 GFAP
43 ileum cancer 10.0 ENO2 GFAP
44 adult medulloblastoma 10.0 ENO2 GFAP
45 dysgerminoma of ovary 10.0 ENO2 GFAP
46 ganglioneuroma 10.0 ENO2 GFAP
47 rhabdomyosarcoma 2 10.0 DES ENO2
48 neuroma 10.0 ENO2 GFAP
49 testis seminoma 10.0 GFAP PTPRC
50 bednar tumor 10.0 ENO2 VIM

Graphical network of the top 20 diseases related to Primitive Neuroectodermal Tumor of the Cervix Uteri:



Diseases related to Primitive Neuroectodermal Tumor of the Cervix Uteri

Symptoms & Phenotypes for Primitive Neuroectodermal Tumor of the Cervix Uteri

MGI Mouse Phenotypes related to Primitive Neuroectodermal Tumor of the Cervix Uteri:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.02 DES ENO2 GFAP PTPRC VIM

Drugs & Therapeutics for Primitive Neuroectodermal Tumor of the Cervix Uteri

Search Clinical Trials , NIH Clinical Center for Primitive Neuroectodermal Tumor of the Cervix Uteri

Genetic Tests for Primitive Neuroectodermal Tumor of the Cervix Uteri

Anatomical Context for Primitive Neuroectodermal Tumor of the Cervix Uteri

MalaCards organs/tissues related to Primitive Neuroectodermal Tumor of the Cervix Uteri:

41
Cervix, Brain, Kidney, Bone, Ovary, Smooth Muscle, Pineal

Publications for Primitive Neuroectodermal Tumor of the Cervix Uteri

Articles related to Primitive Neuroectodermal Tumor of the Cervix Uteri:

# Title Authors Year
1
Primitive neuroectodermal tumor of the cervix uteri: a case report -- changing concepts in therapy. ( 15979131 )
2005
2
Primitive neuroectodermal tumor of the cervix uteri. A case report. ( 9065588 )
1997

Variations for Primitive Neuroectodermal Tumor of the Cervix Uteri

Expression for Primitive Neuroectodermal Tumor of the Cervix Uteri

Search GEO for disease gene expression data for Primitive Neuroectodermal Tumor of the Cervix Uteri.

Pathways for Primitive Neuroectodermal Tumor of the Cervix Uteri

Pathways related to Primitive Neuroectodermal Tumor of the Cervix Uteri according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.45 GFAP VIM
2 11.15 GFAP VIM
3 11.01 DES VIM
4
Show member pathways
10.83 DES GFAP VIM
5
Show member pathways
10.61 DES VIM
6 10.4 DES GFAP VIM

GO Terms for Primitive Neuroectodermal Tumor of the Cervix Uteri

Cellular components related to Primitive Neuroectodermal Tumor of the Cervix Uteri according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.46 DES ENO2 PTPRC VIM
2 intermediate filament cytoskeleton GO:0045111 8.96 DES GFAP
3 intermediate filament GO:0005882 8.8 DES GFAP VIM

Biological processes related to Primitive Neuroectodermal Tumor of the Cervix Uteri according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of neuron projection development GO:0010977 9.37 GFAP VIM
2 muscle filament sliding GO:0030049 9.32 DES VIM
3 astrocyte development GO:0014002 9.26 GFAP VIM
4 Bergmann glial cell differentiation GO:0060020 9.16 GFAP VIM
5 intermediate filament-based process GO:0045103 8.96 GFAP VIM
6 intermediate filament organization GO:0045109 8.8 DES GFAP VIM

Molecular functions related to Primitive Neuroectodermal Tumor of the Cervix Uteri according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.8 DES GFAP VIM

Sources for Primitive Neuroectodermal Tumor of the Cervix Uteri

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