MCID: PRM284
MIFTS: 30

Primitive Neuroectodermal Tumor of the Cervix Uteri

Categories: Cancer diseases, Neuronal diseases, Rare diseases, Reproductive diseases

Aliases & Classifications for Primitive Neuroectodermal Tumor of the Cervix Uteri

MalaCards integrated aliases for Primitive Neuroectodermal Tumor of the Cervix Uteri:

Name: Primitive Neuroectodermal Tumor of the Cervix Uteri 60
Malignant Peripheral Neuroectodermal Tumor of the Cervix Uteri 60
Cervical Malignant Peripheral Neuroectodermal Tumor 60
Peripheral Neuroectodermal Cancer of Cervix Uteri 60
Cervical Peripheral Neuroectodermal Cancer 60

Classifications:



External Ids:

ICD10 via Orphanet 35 C53.0 C53.1 C53.8
Orphanet 60 ORPHA213812

Summaries for Primitive Neuroectodermal Tumor of the Cervix Uteri

MalaCards based summary : Primitive Neuroectodermal Tumor of the Cervix Uteri, also known as malignant peripheral neuroectodermal tumor of the cervix uteri, is related to ewing's family of tumors and gliomatosis peritonei. An important gene associated with Primitive Neuroectodermal Tumor of the Cervix Uteri is DES (Desmin), and among its related pathways/superpathways are Spinal Cord Injury and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include cervix, brain and ovary, and related phenotype is cellular.

Related Diseases for Primitive Neuroectodermal Tumor of the Cervix Uteri

Diseases related to Primitive Neuroectodermal Tumor of the Cervix Uteri via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 141)
# Related Disease Score Top Affiliating Genes
1 ewing's family of tumors 10.4
2 gliomatosis peritonei 10.2 DES GFAP
3 infantile digital fibromatosis 10.2 DES VIM
4 fibromatosis 10.2 DES VIM
5 lymphangiomatosis 10.2 DES VIM
6 angiolipoma 10.2 DES VIM
7 cutaneous leiomyosarcoma 10.2 DES GFAP
8 spindle cell lipoma 10.2 DES VIM
9 benign metastasizing leiomyoma 10.2 DES VIM
10 leiomyoma 10.2 DES VIM
11 spindle cell rhabdomyosarcoma 10.2 DES GFAP
12 biphasic synovial sarcoma 10.2 DES VIM
13 cystic nephroma 10.2 DES VIM
14 juvenile xanthogranuloma 10.2 DES VIM
15 pleomorphic liposarcoma 10.2 DES VIM
16 liposarcoma 10.2 DES VIM
17 perivascular epithelioid cell tumor 10.2 DES VIM
18 cutaneous fibrous histiocytoma 10.2 DES VIM
19 fibrous histiocytoma 10.2 DES VIM
20 congenital fibrosarcoma 10.2 DES VIM
21 mesenchymal chondrosarcoma 10.2 DES VIM
22 pseudosarcomatous fibromatosis 10.2 DES VIM
23 spindle cell sarcoma 10.2 DES VIM
24 rhabdoid meningioma 10.1 GFAP VIM
25 chordoid meningioma 10.1 GFAP VIM
26 embryonal sarcoma 10.1 DES VIM
27 clear cell meningioma 10.1 GFAP VIM
28 ependymoblastoma 10.1 GFAP VIM
29 myxopapillary ependymoma 10.1 GFAP VIM
30 smooth muscle tumor 10.1 DES VIM
31 angiocentric glioma 10.1 GFAP VIM
32 malignant ectomesenchymoma 10.1 DES ENO2
33 ectomesenchymoma 10.1 DES ENO2
34 medulloepithelioma 10.1 GFAP VIM
35 hemangiopericytoma, malignant 10.1 DES VIM
36 anaplastic ependymoma 10.1 GFAP VIM
37 infantile myofibromatosis 10.1 DES VIM
38 chondromyxoid fibroma 10.1 DES VIM
39 intracranial cysts 10.1 ENO2 GFAP
40 bednar tumor 10.1 ENO2 VIM
41 melanotic medulloblastoma 10.1 ENO2 GFAP
42 papillary tumor of the pineal region 10.1 ENO2 VIM
43 cerebellar medulloblastoma 10.1 ENO2 GFAP
44 central nervous system primitive neuroectodermal neoplasm 10.1 ENO2 GFAP
45 plexiform schwannoma 10.1 ENO2 GFAP
46 spindle cell carcinoma 10.1 DES VIM
47 cerebral neuroblastoma 10.1 ENO2 GFAP
48 subependymal glioma 10.1 ENO2 GFAP
49 papillary ependymoma 10.1 ENO2 GFAP
50 cerebral ventricle cancer 10.1 ENO2 GFAP

Graphical network of the top 20 diseases related to Primitive Neuroectodermal Tumor of the Cervix Uteri:



Diseases related to Primitive Neuroectodermal Tumor of the Cervix Uteri

Symptoms & Phenotypes for Primitive Neuroectodermal Tumor of the Cervix Uteri

MGI Mouse Phenotypes related to Primitive Neuroectodermal Tumor of the Cervix Uteri:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.02 DES ENO2 GFAP PTPRC VIM

Drugs & Therapeutics for Primitive Neuroectodermal Tumor of the Cervix Uteri

Search Clinical Trials , NIH Clinical Center for Primitive Neuroectodermal Tumor of the Cervix Uteri

Genetic Tests for Primitive Neuroectodermal Tumor of the Cervix Uteri

Anatomical Context for Primitive Neuroectodermal Tumor of the Cervix Uteri

MalaCards organs/tissues related to Primitive Neuroectodermal Tumor of the Cervix Uteri:

42
Cervix, Brain, Ovary, Pineal, Kidney, Bone, Smooth Muscle

Publications for Primitive Neuroectodermal Tumor of the Cervix Uteri

Articles related to Primitive Neuroectodermal Tumor of the Cervix Uteri:

# Title Authors Year
1
Primitive neuroectodermal tumor of the cervix uteri: a case report -- changing concepts in therapy. ( 15979131 )
2005
2
Primitive neuroectodermal tumor of the cervix uteri. A case report. ( 9065588 )
1997

Variations for Primitive Neuroectodermal Tumor of the Cervix Uteri

Expression for Primitive Neuroectodermal Tumor of the Cervix Uteri

Search GEO for disease gene expression data for Primitive Neuroectodermal Tumor of the Cervix Uteri.

Pathways for Primitive Neuroectodermal Tumor of the Cervix Uteri

Pathways related to Primitive Neuroectodermal Tumor of the Cervix Uteri according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.45 GFAP VIM
2 11.15 GFAP VIM
3 11.01 DES VIM
4
Show member pathways
10.83 DES GFAP VIM
5
Show member pathways
10.61 DES VIM
6 10.4 DES GFAP VIM

GO Terms for Primitive Neuroectodermal Tumor of the Cervix Uteri

Cellular components related to Primitive Neuroectodermal Tumor of the Cervix Uteri according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.46 DES ENO2 PTPRC VIM
2 intermediate filament cytoskeleton GO:0045111 8.96 DES GFAP
3 intermediate filament GO:0005882 8.8 DES GFAP VIM

Biological processes related to Primitive Neuroectodermal Tumor of the Cervix Uteri according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of neuron projection development GO:0010977 9.37 GFAP VIM
2 muscle filament sliding GO:0030049 9.32 DES VIM
3 astrocyte development GO:0014002 9.26 GFAP VIM
4 Bergmann glial cell differentiation GO:0060020 9.16 GFAP VIM
5 intermediate filament-based process GO:0045103 8.96 GFAP VIM
6 intermediate filament organization GO:0045109 8.8 DES GFAP VIM

Molecular functions related to Primitive Neuroectodermal Tumor of the Cervix Uteri according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.8 DES GFAP VIM

Sources for Primitive Neuroectodermal Tumor of the Cervix Uteri

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