Drugs for Prion Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):
(show all 27)
# |
|
Name |
Status |
Phase |
Clinical Trials |
Cas Number |
PubChem Id |
1 |
|
Glycerol |
Approved, Investigational |
Phase 2, Phase 3 |
|
56-81-5 |
753 |
Synonyms:
1,2,3-propanetriol
1,2,3-Propanetriol
1,2,3-trihydroxypropane
1,2,3-Trihydroxypropane
Bulbold
Cristal
e 422
Emery 916
Glyceol opthalgan
Glycerin
Glycerin, anhydrous
Glycerin,anhydrous
Glycerine
glycérine
Glycerinum
Glyceritol
Glycerol
glycérol
|
Glycerolum
Glycyl alcohol
Glyrol
Glysanin
Glyzerin
Gro
IFP
Incorporation factor
Mackstat H 66
Monoctanoin component D
Oelsuess
Ölsüß
Osmoglyn
Pricerine 9091
Propanetriol
RG-S
Trihydroxypropane
Tryhydroxypropane
|
|
2 |
|
Coal tar |
Approved |
Phase 2 |
|
8007-45-2 |
|
Synonyms:
|
3 |
|
Quinacrine |
Investigational |
Phase 2 |
|
83-89-6 |
237 |
Synonyms:
130-42-7
130-42-7 (mono-hydrochloride)
2-methoxy-6-chloro-9-diethylaminopentylaminoacridine
2-Methoxy-6-chloro-9-diethylaminopentylaminoacridine
316-05-2 (dimesylate)
3-chloro-7-methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine
3-chloro-7-Methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine
3-Chloro-7-methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine
4-N-(6-chloro-2-methoxyacridin-9-yl)-1-N,1-N-diethylpentane-1,4-diamine
6151-30-0
6151-30-0 (di-hydrochloride, di-hydrate)
69-05-6
69-05-6 (di-hydrochloride)
6-chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxyacridine
6-chloro-9-((4-(diethylamino)-1-Methylbutyl)amino)-2-methoxyacridine
6-Chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxyacridine
78901-94-7
78901-94-7 (monoacetate)
83-89-6
83-89-6 (Parent)
866 R.P.
AB00053540
AC1L18SD
AC1L3ZIX
AC1MBFYF
AC1NS008
AC1Q2BPT
acetic acid
Acirchine
acrichine
Acrichine
Acrinamine
Acriquine
AI3-04467
AKOS000541535
AKOS004910405
Akrichin
Antimalarina
Arichin
atabrine
Atabrine
Atabrine dihydrochloride
Atabrine hydrochloride
Atabrine hydrochloride dihydrate
atebrin
Atebrin
Atebrine
BAS 00439963
BPBio1_000348
BRD-A45889380-336-03-4
BSPBio_000316
BSPBio_002112
C07339
C23H30ClN3O.2HCl.2H2O
CCRIS 8633
CHEBI:8711
CHEMBL546257
CHEMBL7568
chinacrin
CID149640
CID237
CID2725002
CID5351141
cMAP_000067
CPD000449289
D08179
DB01103
Dihydrochloride, quinacrine
Dimesylate, quinacrine
DivK1c_000101
EINECS 201-508-7
EINECS 204-989-1
Erion
Erion Hydrochloride
GNF-PF-5448
Haffkinine
HMS1568P18
HMS2090L03
HSDB 3253
Hydrochloride, quinacrine
IDI1_000101
Italchin
Italchine
KBio1_000101
KBio2_001409
KBio2_002507
KBio2_003977
KBio2_005075
KBio2_006545
KBio2_007643
KBio3_001612
KBio3_002985
|
KBioGR_001011
KBioGR_002507
KBioSS_001409
KBioSS_002515
Lopac0_000970
LS-14293
LS-14294
LS-190025
Malaricida
Mecryl
Mepacrina
Mepacrina [INN-Spanish]
mepacrine
Mepacrine
Mepacrine (INN)
Mepacrine [INN:BAN]
Mepacrine HCl
Mepacrine hydrochloride dihydrate
Mepacrinum
Mepacrinum [INN-Latin]
Methoquine
Metochin
MLS000758289
MolPort-001-739-072
MolPort-004-285-521
Monoacetate, quinacrine
Monohydrochloride, quinacrine
Monomesylate, quinacrine
MS-1557
N(4)-(6-chloro-2-methoxy-9-acridinyl)-N(1),N(1)-diethyl-1,4-pentanediamine
N(4)-(6-chloro-2-Methoxy-9-acridinyl)-N(1),N(1)-diethyl-1,4-pentanediamine
N'-(6-chloro-2-methoxyacridin-9-yl)-N,N-diethylpentane-1,4-diamine
N*4*-(6-Chloro-2-methoxy-acridin-9-yl)-N*1*,N*1*-diethyl-pentane-1,4-diamine
N~4~-(6-chloro-2-methoxyacridin-9-yl)-N~1~,N~1~-diethylpentane-1,4-diamine
N~4~-[6-chloro-2-(methyloxy)acridin-9-yl]-N~1~,N~1~-diethylpentane-1,4-diamine
N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-1,4-pentanediamine
N4-(6-Chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-1,4-pentanediamine
N4-(6-Chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-1,4-pentanediamine monoacetate
NCGC00015874-04
NCGC00162300-01
NCGC00180899-01
NCGC00180969-01
nchembio.215-comp6
nchembio873-comp30
NCI60_000926
NINDS_000101
NSC14229
Palacrin
Palusan
Pentilen
Prestwick_650
Prestwick0_000318
Prestwick1_000318
Prestwick2_000318
Prestwick3_000318
Quinacrin
quinacrine
Quinacrine acetate
Quinacrine dihydrochloride
Quinacrine dihydrochloride dihydrate
Quinacrine dihydrochloride mustard
Quinacrine dihydrochloride, dihydrate
Quinacrine Dihydrochloride, Dihydrate
Quinacrine dihyrochloride, (R)-isomer
Quinacrine dihyrochloride, (S)-isomer
Quinacrine dimesylate
Quinacrine hydrochloride
Quinacrine hydrochloride dihydrate
Quinacrine monoacetate
Quinacrine monohydrochloride
Quinacrine monomesylate
Quinacrine, (+-)-isomer
Quinacrine, (R)-isomer
Quinacrine, (S)-isomer
Quinactine
RP 866
RP-866 (Dihydrochloride dihydrate)
SAM001247040
SMR000449289
SN-390 (Dihydrochloride dihydrate)
SPBio_000676
SPBio_002535
Spectrum_000929
Spectrum2_000888
Spectrum3_000606
Spectrum4_000496
Spectrum5_001405
St 439
STL061087
TCMDC-125480
WLN: T C666 BNJ EG IMY1&3N2&2 LO1 &GH 2
|
|
4 |
|
Anthelmintics |
|
Phase 2 |
|
|
|
5 |
|
Anti-Infective Agents |
|
Phase 2 |
|
|
|
6 |
|
Antiparasitic Agents |
|
Phase 2 |
|
|
|
7 |
|
Antiprotozoal Agents |
|
Phase 2 |
|
|
|
8 |
|
Antimalarials |
|
Phase 2 |
|
|
|
9 |
|
Insulin, Globin Zinc |
|
Phase 1, Phase 2 |
|
|
|
10 |
|
insulin |
|
Phase 1, Phase 2 |
|
|
|
11 |
|
Liver Extracts |
|
Phase 1, Phase 2 |
|
|
|
12 |
|
Bifidobacterium |
|
Phase 2 |
|
|
|
13 |
|
Methylprednisolone |
Approved, Vet_approved |
Phase 1 |
|
83-43-2 |
6741 |
Synonyms:
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
1-dehydro-6alpha-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6a-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6-alpha-Methylprednisolone
6a-Methyl-11b,17a,21-triol-1,4-pregnadiene-3,20-dione
6-Methylprednisolone
6α-methyl-11β,17α,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
AC1L1N7A
Artisone-wyeth
Artisone-Wyeth
Besonia
Bio-0658
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
delta(1)-6alpha-Methylhydrocortisone
Delta(1)-6alpha-Methylhydrocortisone
delta(1)-6a-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
Depo-Medrol (acetate)
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
Lemod
LMST02030178
LS-118498
M0639_SIGMA
M1665
Medesone
Medixon
Medlone 21
Medrate
Medric acid
|
Medrol
Medrol (TN)
Medrol adt pak
Medrol Adt Pak
Medrol dosepak
Medrol Dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
MEPRDL
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
methylprednisolone
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
methylprenisolone
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [Dcit]
Metilprednisolone [DCIT]
Metipred
Metrisone
Metrocort
Metysolon
MLS000028541
MLS001148159
MLS002207191
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
Nirypan
Noretona
NSC19987
NSC-19987
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick_622
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Promacortine
Reactenol
S1733_Selleck
SAM002589984
Sieropresol
SMR000058330
Solomet
SPBio_002377
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
δ(1)-6a-methylhydrocortisone
δ(1)-6α-methylhydrocortisone
|
|
14 |
|
Prednisolone phosphate |
Approved, Vet_approved |
Phase 1 |
|
302-25-0 |
|
Synonyms:
Prednisolone 21-(dihydrogen phosphate)
Prednisolone 21-monophosphate
|
Prednisolone 21-phosphate
|
|
15 |
|
Methylprednisolone hemisuccinate |
Approved |
Phase 1 |
|
2921-57-5 |
|
Synonyms:
Methylprednisolone hydrogen succinate
|
Methylprednisolone succinate
|
|
16 |
|
Prednisolone |
Approved, Vet_approved |
Phase 1 |
|
50-24-8 |
5755 |
Synonyms:
(11b)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
(11β)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11b,17a,21-triol-3,20-dione
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-pregnadiene-11β,17α,21-triol-3,20-dione
1,4-Pregnadiene-11β,17α,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11b,17a,21-triol
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1,4-pregnadiene-3,20-dione-11β,17α,21-triol
1,4-Pregnadiene-3,20-dione-11β,17α,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11b,17a,21-Trihydroxy-1,4-pregnadiene
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
3,20-dioxo-11β,17α,21-trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
Bio-0666
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
Codelcortone
Co-Hydeltra
CO-Hydeltra
component of Ataraxoid
component of K-Predne-Dome
Cordrol
Cortalone
Cotogesic
Cotolone
CPD000718761
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
delta(1)-Cortisol
delta(1)-Dehydrocortisol
Delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
Delta(1)-dehydrohydrocortisone
Delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
Delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Deltacortenol
Deltacortril
Deltacortril Enteric
delta-dehydrocortisol
delta-dehydrohydrocortisone
Delta-Ef-Cortelan
delta-hydrocortisone
Deltahydrocortisone
Deltasolone
Delta-stab
Delta-Stab
Deltisilone
Depo-Medrol
Derpo Pd
Derpo PD
Dexa-Cortidelt hostacortin H
Dexa-Cortidelt Hostacortin H
Di adreson F
Di Adreson F
Di-adreson F
Di-Adreson F
Di-adreson-F
DiAdresonF
Di-Adreson-F
Dicortol
Donisolone
Dydeltrone
Eazolin D
Econopred
Econopred Plus
EINECS 200-021-7
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
HMS1568H10
HMS2090J05
Hostacortin H
HSDB 3385
Hydeltra
Hydeltrasol
Hydeltra-Tba
Hydeltrone
|
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
Inflamase Forte
Inflamase Mild
I-Pred
K 1557
Key-Pred
Klismacort
Lentosone
Lite Pred
LMST02030179
LS-7669
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone acetate
Methylprednisolone Acetate
Meticortelone
Meti-Derm
Metreton
MLS001304083
MLS002154250
MLS002207037
MolPort-002-507-147
M-Predrol
NCGC00179649-01
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
NSC 9120
NSC9120
NSC9900
Ocu-Pred
Ocu-Pred Forte
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
PRDL
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
PRED-G
Predisolone sodium phosphate
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Prednicen
Predni-Dome
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
prednisolone
Prednisolone
Prednisolone (anhydrous)
Prednisolone (JP15/USP/INN)
Prednisolone [INN:BAN:JAN]
Prednisolone acetate
Prednisolone Acetate
Prednisolone sodium phosphate
Prednisolone Sodium Phosphate
Prednisolone tebutate
Prednisolone Tebutate
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick_404
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Rolisone
S1737_Selleck
SAM002264639
Scherisolon
SMR000718761
Solone
SPBio_002367
Steran
Sterane
Sterolone
Supercortisol
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-hydrogen
Ultracortene-Hydrogen
UNII-9PHQ9Y1OLM
ZINC03833821
δ(1)-dehydrocortisol
δ(1)-dehydrohydrocortisone
δ(1)-hydrocortisone
|
|
17 |
|
Prednisolone acetate |
Approved, Vet_approved |
Phase 1 |
|
52-21-1 |
|
18 |
|
Prednisolone hemisuccinate |
Experimental |
Phase 1 |
|
2920-86-7 |
|
Synonyms:
(+)-prednisolone hemisuccinate
Prednisolonbisuccinat
Prednisolone 21-hemisuccinate
Prednisolone 21-succinate
|
Prednisolone bisuccinate
Prednisolone hydrogen succinate
Prednisolone succinate
|
|
19 |
|
Anesthetics |
|
Phase 1 |
|
|
|
20 |
|
Methylprednisolone Acetate |
|
Phase 1 |
|
|
|
21 |
|
Cyclosporins |
|
Phase 1 |
|
|
|
22 |
|
Thymoglobulin |
|
Phase 1 |
|
|
|
23 |
|
Antilymphocyte Serum |
|
Phase 1 |
|
|
|
24 |
|
Thrombin |
Approved, Investigational |
|
|
|
|
Synonyms:
coagulation factor II
Thrombin bovine
|
Thrombin, Topical (Bovine)
|
|
25 |
|
Epoetin alfa |
|
|
|
113427-24-0 |
|
26 |
|
Antibodies |
|
|
|
|
|
27 |
|
Immunoglobulins |
|
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Interventional clinical trials:
(show all 16)
# |
Name |
Status |
NCT ID |
Phase |
Drugs |
1 |
A Randomized Controlled Trial of the Safety and Efficacy of Fecal Microbiota Transplantation in a Population With Bipolar Disorder |
Recruiting |
NCT03279224 |
Phase 2, Phase 3 |
|
2 |
Novel Therapeutics For Prion Diseases: A Randomized, Double-blinded, Placebo-controlled Study of the Efficacy of Quinacrine in the Treatment of Sporadic Creutzfeldt-Jakob Disease |
Completed |
NCT00183092 |
Phase 2 |
Quinacrine;Placebo |
3 |
Bovine Colostrum for Patients With Non Alcoholic Fatty Liver Disease |
Completed |
NCT01016418 |
Phase 1, Phase 2 |
|
4 |
The Safety and Effectiveness of Probiotic Supplementation on Bipolar Depression: a Proof of Concept Randomized Controlled Trial |
Terminated |
NCT02155972 |
Phase 2 |
|
5 |
Phase I Serum-Free Cultured Thymus Transplantation in DiGeorge Anomaly, IND9836 |
Terminated |
NCT00849888 |
Phase 1 |
|
6 |
PRION-1: Quinacrine for Human Prion Disease. A Partially Randomized Patient Preference Trial to Evaluate the Activity and Safety of Quinacrine in Human Prion Disease |
Completed |
NCT00104663 |
|
Quinacrine |
7 |
CardioCel Tri-leaflet Repair Study; a Prospective, Non-randomised, Single Arm, Multi-centre Clinical Investigation |
Completed |
NCT02629328 |
|
|
8 |
A Prospective, Immunogenicity Surveillance Registry (PRIMS) to Estimate the Incidence of Erythropoietin Antibody-Mediated Pure Red Cell Aplasia Among Subjects With Chronic Renal Failure and Subcutaneous Exposure to Recombinant Erythropoietin Products |
Completed |
NCT00391287 |
|
|
9 |
Vascular Post Market Review |
Completed |
NCT02681341 |
|
|
10 |
The Clinical Utility of the Congo-Red Dot Test for Diagnosis and Early Prediction of Preeclampsia During Pregnancy |
Completed |
NCT02455544 |
|
|
11 |
FDDNP-PET Imaging in Persons at Risk for Chronic Traumatic Encephalopathy |
Completed |
NCT02003183 |
|
|
12 |
Enhanced CJD Surveillance in the Older Population |
Recruiting |
NCT02629640 |
|
|
13 |
Development and Application of a Novel Neurorehabilitation Technology With Paired Associative Nerve Stimulation in Spinal Cord Injured Subjects |
Recruiting |
NCT04194099 |
|
|
14 |
The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Registry: Reliable Assessment to Enable Research and Improve Clinical Care |
Recruiting |
NCT02443636 |
|
|
15 |
Therapeutic Antibodies Against Prion Diseases From PRNP Mutation Carriers |
Active, not recruiting |
NCT02837705 |
|
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16 |
The Role of the Coagulation Pathway at the Synapse in Prion Diseases |
Not yet recruiting |
NCT02480725 |
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Cochrane evidence based reviews: prion diseases
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