MCID: PRG077
MIFTS: 20

Progressive Nodular Histiocytosis

Categories: Bone diseases, Rare diseases, Skin diseases

Aliases & Classifications for Progressive Nodular Histiocytosis

MalaCards integrated aliases for Progressive Nodular Histiocytosis:

Name: Progressive Nodular Histiocytosis 58

Characteristics:

Orphanet epidemiological data:

58
progressive nodular histiocytosis
Inheritance: Not applicable;

Classifications:

Orphanet: 58  
Rare systemic and rhumatological diseases
Rare skin diseases


External Ids:

ICD10 via Orphanet 33 D76.3
Orphanet 58 ORPHA158022

Summaries for Progressive Nodular Histiocytosis

MalaCards based summary : Progressive Nodular Histiocytosis is related to non-langerhans-cell histiocytosis and cutaneous fibrous histiocytoma. An important gene associated with Progressive Nodular Histiocytosis is ACTC1 (Actin Alpha Cardiac Muscle 1). Affiliated tissues include skin, and related phenotypes are subcutaneous nodule and papule

Wikipedia : 73 Progressive nodular histiocytosis is a cutaneous condition clinically characterized by the development... more...

Related Diseases for Progressive Nodular Histiocytosis

Graphical network of the top 20 diseases related to Progressive Nodular Histiocytosis:



Diseases related to Progressive Nodular Histiocytosis

Symptoms & Phenotypes for Progressive Nodular Histiocytosis

Human phenotypes related to Progressive Nodular Histiocytosis:

58 31
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 subcutaneous nodule 58 31 hallmark (90%) Very frequent (99-80%) HP:0001482
2 papule 58 31 hallmark (90%) Very frequent (99-80%) HP:0200034
3 fever 58 31 occasional (7.5%) Occasional (29-5%) HP:0001945
4 cachexia 58 31 occasional (7.5%) Occasional (29-5%) HP:0004326

Drugs & Therapeutics for Progressive Nodular Histiocytosis

Search Clinical Trials , NIH Clinical Center for Progressive Nodular Histiocytosis

Genetic Tests for Progressive Nodular Histiocytosis

Anatomical Context for Progressive Nodular Histiocytosis

MalaCards organs/tissues related to Progressive Nodular Histiocytosis:

40
Skin

Publications for Progressive Nodular Histiocytosis

Articles related to Progressive Nodular Histiocytosis:

(show all 27)
# Title Authors PMID Year
1
Non-Langerhans cell histiocytosis xanthogranuloma patient with varying histopathology leading to progressive nodular histiocytosis. 61
33586878 2021
2
[Treatment-refractory progressive nodular histiocytosis]. 61
32974701 2020
3
Progressive Nodular Histiocytosis. 61
32501796 2020
4
Progressive Nodular Histiocytosis with Large Nodules and a Bulky Mass. 61
30226532 2019
5
Indeterminate cell histiocytosis in a Chinese patient with progressive and extensive nodular lesions and mixed indeterminate cell and macrophage-monocyte lineage. 61
29469188 2018
6
Progressive nodular histiocytosis improved by methotrexate. 61
29165296 2017
7
A Case with Juvenile Xanthogranuloma and Progressive Nodular Histiocytosis Overlap. 61
28297144 2017
8
Laryngeal involvement with fatal outcome in progressive nodular histiocytosis: A rare case report. 61
27990389 2016
9
Progressive Nodular Histiocytosis Associated with Eale's Disease. 61
26288410 2015
10
Effective surgical treatment of progressive nodular histiocytosis. 61
24428162 2014
11
Reddish-brown nodules and papules in an elderly man. Progressive nodular histiocytosis. 61
23945611 2013
12
Progressive nodular histiocytosis with normal karyotypic analysis. 61
24011326 2013
13
Progressive nodular histiocytosis. 61
23231636 2013
14
Progressive nodular histiocytosis: a case report and literature review. 61
22098005 2011
15
Generalized eruptive histiocytosis mimicking leprosy. 61
21727699 2011
16
Progressive nodular histiocytosis. 61
21083716 2010
17
Laryngeal involvement in progressive nodular histiocytosis: a case report. 61
20479385 2010
18
Progressive nodular histiocytosis: a case report with literature review, and discussion of differential diagnosis and classification. 61
19878386 2009
19
Progressive nodular histiocytosis - A five-year follow up. 61
18424392 2008
20
[Progressive nodular histiocytosis--rare variant of cutaneous non-Langerhans cell histiocytosis]. 61
16626320 2006
21
Generalized eruptive histiocytosis. 61
14699379 2004
22
Papular xanthoma associated with angiokeratoma of Fordyce: considerations on the nosography of this rare non-Langerhans cell histiocytoxanthomatosis. 61
12592087 2003
23
Progressive nodular histiocytosis in a child with a hypothalamic tumor. 61
11852916 2002
24
Progressive nodular histiocytosis accompanied by systemic disorders. 61
10971342 2000
25
Non-Langerhans cell histiocytoses. A new unifying concept. 61
8902096 1996
26
Solitary and generalized variants of spindle cell xanthogranuloma (progressive nodular histiocytosis). 61
7557901 1995
27
Progressive nodular histiocytosis. 61
8335756 1993

Variations for Progressive Nodular Histiocytosis

Expression for Progressive Nodular Histiocytosis

Search GEO for disease gene expression data for Progressive Nodular Histiocytosis.

Pathways for Progressive Nodular Histiocytosis

GO Terms for Progressive Nodular Histiocytosis

Cellular components related to Progressive Nodular Histiocytosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood microparticle GO:0072562 8.62 F13A1 ACTC1

Sources for Progressive Nodular Histiocytosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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