MCID: PRG115
MIFTS: 12

Progressive Supranuclear Palsy-Progressive Non-Fluent Aphasia Syndrome

Categories: Eye diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Progressive Supranuclear Palsy-Progressive Non-Fluent Aphasia...

MalaCards integrated aliases for Progressive Supranuclear Palsy-Progressive Non-Fluent Aphasia Syndrome:

Name: Progressive Supranuclear Palsy-Progressive Non-Fluent Aphasia Syndrome 60
Progressive Supranuclear Palsy-Apraxia of Speech Syndrome 60
Psp-Pnfa 60
Psp-Aos 60

Characteristics:

Orphanet epidemiological data:

60
progressive supranuclear palsy-progressive non-fluent aphasia syndrome
Inheritance: Not applicable; Prevalence: <1/1000000 (Worldwide); Age of onset: Adult; Age of death: elderly;

Classifications:



External Ids:

ICD10 via Orphanet 35 G23.1
Orphanet 60 ORPHA240112

Summaries for Progressive Supranuclear Palsy-Progressive Non-Fluent Aphasia...

MalaCards based summary : Progressive Supranuclear Palsy-Progressive Non-Fluent Aphasia Syndrome, is also known as progressive supranuclear palsy-apraxia of speech syndrome. An important gene associated with Progressive Supranuclear Palsy-Progressive Non-Fluent Aphasia Syndrome is MAPT (Microtubule Associated Protein Tau). Affiliated tissues include eye, and related phenotypes are dysphagia and neurological speech impairment

Related Diseases for Progressive Supranuclear Palsy-Progressive Non-Fluent Aphasia...

Symptoms & Phenotypes for Progressive Supranuclear Palsy-Progressive Non-Fluent Aphasia...

Human phenotypes related to Progressive Supranuclear Palsy-Progressive Non-Fluent Aphasia Syndrome:

60 (show all 21)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 dysphagia 60 Occasional (29-5%)
2 neurological speech impairment 60 Very frequent (99-80%)
3 falls 60 Occasional (29-5%)
4 aphasia 60 Occasional (29-5%)
5 mental deterioration 60 Frequent (79-30%)
6 clumsiness 60 Occasional (29-5%)
7 parkinsonism 60 Occasional (29-5%)
8 apathy 60 Frequent (79-30%)
9 postural instability 60 Occasional (29-5%)
10 speech apraxia 60 Very frequent (99-80%)
11 vertical supranuclear gaze palsy 60 Occasional (29-5%)
12 speech articulation difficulties 60 Frequent (79-30%)
13 poor speech 60 Frequent (79-30%)
14 abnormal speech prosody 60 Frequent (79-30%)
15 deficit in phonologic short-term memory 60 Very frequent (99-80%)
16 progressive extrapyramidal muscular rigidity 60 Occasional (29-5%)
17 grammar-specific speech disorder 60 Very frequent (99-80%)
18 spoken word recognition deficit 60 Very frequent (99-80%)
19 anomia 60 Very frequent (99-80%)
20 stuttering 60 Very frequent (99-80%)
21 limb apraxia 60 Occasional (29-5%)

Drugs & Therapeutics for Progressive Supranuclear Palsy-Progressive Non-Fluent Aphasia...

Search Clinical Trials , NIH Clinical Center for Progressive Supranuclear Palsy-Progressive Non-Fluent Aphasia Syndrome

Genetic Tests for Progressive Supranuclear Palsy-Progressive Non-Fluent Aphasia...

Anatomical Context for Progressive Supranuclear Palsy-Progressive Non-Fluent Aphasia...

MalaCards organs/tissues related to Progressive Supranuclear Palsy-Progressive Non-Fluent Aphasia Syndrome:

42
Eye

Publications for Progressive Supranuclear Palsy-Progressive Non-Fluent Aphasia...

Variations for Progressive Supranuclear Palsy-Progressive Non-Fluent Aphasia...

Expression for Progressive Supranuclear Palsy-Progressive Non-Fluent Aphasia...

Search GEO for disease gene expression data for Progressive Supranuclear Palsy-Progressive Non-Fluent Aphasia Syndrome.

Pathways for Progressive Supranuclear Palsy-Progressive Non-Fluent Aphasia...

GO Terms for Progressive Supranuclear Palsy-Progressive Non-Fluent Aphasia...

Sources for Progressive Supranuclear Palsy-Progressive Non-Fluent Aphasia...

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....