MCID: PRL016
MIFTS: 16

Proliferative Type Fibrocystic Change of Breast

Categories: Cancer diseases

Aliases & Classifications for Proliferative Type Fibrocystic Change of Breast

MalaCards integrated aliases for Proliferative Type Fibrocystic Change of Breast:

Name: Proliferative Type Fibrocystic Change of Breast 12 15
Fibrocystic Disease, Proliferative Type with Atypia 12
Fibrocystic Change, Proliferative Type with Atypia 12
Proliferating Lesion of the Breast Without Atypia 12
Proliferating Lesion of Breast Without Atypia 12
Breast Fibrocystic Change, Proliferative Type 74
Proliferative Fibrocystic Change 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3274
NCIt 51 C8365
SNOMED-CT 69 35813005

Summaries for Proliferative Type Fibrocystic Change of Breast

Disease Ontology : 12 A breast fibrocystic disease that is characterized by the presence of epithelial cell hyperplasia and the absence of epithelial atypia.

MalaCards based summary : Proliferative Type Fibrocystic Change of Breast, also known as fibrocystic disease, proliferative type with atypia, is related to non-proliferative fibrocystic change of the breast and sclerosing adenosis of breast. An important gene associated with Proliferative Type Fibrocystic Change of Breast is GSTO1 (Glutathione S-Transferase Omega 1). The drugs Nicotinamide and Lovastatin have been mentioned in the context of this disorder. Affiliated tissues include breast.

Related Diseases for Proliferative Type Fibrocystic Change of Breast

Diseases related to Proliferative Type Fibrocystic Change of Breast via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 non-proliferative fibrocystic change of the breast 12.6
2 sclerosing adenosis of breast 11.4
3 fibrosclerosis of breast 11.3
4 apocrine adenosis of breast 11.3

Symptoms & Phenotypes for Proliferative Type Fibrocystic Change of Breast

Drugs & Therapeutics for Proliferative Type Fibrocystic Change of Breast

Drugs for Proliferative Type Fibrocystic Change of Breast (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Nicotinamide Approved, Investigational Phase 2 98-92-0 936
2
Lovastatin Approved, Investigational Phase 2 75330-75-5 53232
3
Niacin Approved, Investigational, Nutraceutical Phase 2 59-67-6 938
4 Anticholesteremic Agents Phase 2
5 Vitamin B3 Phase 2
6 Nicotinic Acids Phase 2
7 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 2
8 Dihydromevinolin Phase 2
9 L 647318 Phase 2
10 Antimetabolites Phase 2
11 Hypolipidemic Agents Phase 2
12 Lipid Regulating Agents Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Phase 2 Study of Lovastatin as Breast Cancer Chemoprevention Terminated NCT00285857 Phase 2 Lovastatin
2 Nuclear Morphology of Breast Cells in Ductal Lavage Completed NCT00259597
3 Prolactin Receptor and Breast Diseases Completed NCT00842465

Search NIH Clinical Center for Proliferative Type Fibrocystic Change of Breast

Genetic Tests for Proliferative Type Fibrocystic Change of Breast

Anatomical Context for Proliferative Type Fibrocystic Change of Breast

MalaCards organs/tissues related to Proliferative Type Fibrocystic Change of Breast:

42
Breast

Publications for Proliferative Type Fibrocystic Change of Breast

Variations for Proliferative Type Fibrocystic Change of Breast

Expression for Proliferative Type Fibrocystic Change of Breast

Search GEO for disease gene expression data for Proliferative Type Fibrocystic Change of Breast.

Pathways for Proliferative Type Fibrocystic Change of Breast

GO Terms for Proliferative Type Fibrocystic Change of Breast

Sources for Proliferative Type Fibrocystic Change of Breast

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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