PROA
MCID: PRL045
MIFTS: 16

Proline-Negative Auxotroph of Hamster, Complementation of (PROA)

Aliases & Classifications for Proline-Negative Auxotroph of Hamster, Complementation of

MalaCards integrated aliases for Proline-Negative Auxotroph of Hamster, Complementation of:

Name: Proline-Negative Auxotroph of Hamster, Complementation of 57
Proa 57

External Ids:

OMIM® 57 176770

Summaries for Proline-Negative Auxotroph of Hamster, Complementation of

MalaCards based summary : Proline-Negative Auxotroph of Hamster, Complementation of, also known as proa, is related to legionnaire disease and paroxysmal extreme pain disorder. The drugs Anti-Bacterial Agents and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, bone and lung.

More information from OMIM: 176770

Related Diseases for Proline-Negative Auxotroph of Hamster, Complementation of

Diseases related to Proline-Negative Auxotroph of Hamster, Complementation of via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 legionnaire disease 10.1
2 paroxysmal extreme pain disorder 9.9
3 thrombocytopenic purpura, autoimmune 9.9
4 thrombocytopenia due to platelet alloimmunization 9.9
5 thrombocytopenia 9.9
6 purpura 9.9
7 syphilis 9.9

Graphical network of the top 20 diseases related to Proline-Negative Auxotroph of Hamster, Complementation of:



Diseases related to Proline-Negative Auxotroph of Hamster, Complementation of

Symptoms & Phenotypes for Proline-Negative Auxotroph of Hamster, Complementation of

Clinical features from OMIM®:

176770 (Updated 20-May-2021)

Drugs & Therapeutics for Proline-Negative Auxotroph of Hamster, Complementation of

Drugs for Proline-Negative Auxotroph of Hamster, Complementation of (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Anti-Bacterial Agents
2 Anti-Infective Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Impacto clínico y microbiológico de un Programa de optimización de Antimicrobianos específico Para Centros Socio-sanitarios. Ensayo clínico Aleatorizado Por Grupos. Ensayo PROA-SENIOR Recruiting NCT03543605

Search NIH Clinical Center for Proline-Negative Auxotroph of Hamster, Complementation of

Genetic Tests for Proline-Negative Auxotroph of Hamster, Complementation of

Anatomical Context for Proline-Negative Auxotroph of Hamster, Complementation of

MalaCards organs/tissues related to Proline-Negative Auxotroph of Hamster, Complementation of:

40
Bone Marrow, Bone, Lung

Publications for Proline-Negative Auxotroph of Hamster, Complementation of

Articles related to Proline-Negative Auxotroph of Hamster, Complementation of:

(show top 50) (show all 264)
# Title Authors PMID Year
1
High-frequency induction by 5-azacytidine of proline independence in CHO-K1 cells. 57
6209809 1984
2
Synteny between the pro+ marker and human glutamate oxaloacetate transaminase. 57
1235910 1975
3
Knee osteoarthritis and time-to all-cause mortality in six community-based cohorts: an international meta-analysis of individual participant-level data. 61
33590469 2021
4
First report of soft rot of onion caused by Pectobacterium wasabiae in Japan. 61
33779247 2021
5
Protein A does not induce allosteric structural changes in an IgG1 antibody during binding. 61
33640336 2021
6
Veratrum Alkaloid Determination in Four Cases of Veratrum Aqua Poisonings. 61
33559680 2021
7
First Report of Pectobacterium parmentieri Causing Blackleg on Potato in Inner Mongolia, China. 61
33630693 2021
8
Development of sub-tropically adapted diverse provitamin-A rich maize inbreds through marker-assisted pedigree selection, their characterization and utilization in hybrid breeding. 61
33539427 2021
9
Proscillaridin A inhibits hepatocellular carcinoma progression through inducing mitochondrial damage and autophagy. 61
33201987 2021
10
Zinc metalloprotease ProA of Legionella pneumophila increases alveolar septal thickness in human lung tissue explants by collagen IV degradation. 61
33491325 2021
11
Low expression of carotenoids cleavage dioxygenase 1 (ccd1) gene improves the retention of provitamin-A in maize grains during storage. 61
33068135 2021
12
Simultaneously targeting nitrocellulose and antibody by a dual-headed protein. 61
32971296 2021
13
[Evaluation of training on the programs to optimize antimicrobial use in medical residents of the province of Las Palmas]. 61
32781824 2020
14
Mechanistic insights into viral clearance during the chromatography steps in antibody processes by using virus surrogates. 61
33405373 2020
15
A nuclear protein NsiA from Epichloë festucae interacts with a MAP kinase MpkB and regulates the expression of genes required for symbiotic infection and hyphal cell fusion. 61
32634260 2020
16
Proline metabolism and molecular cloning of AmP5CS in the mangrove Avicennia marina under heat stress. 61
32297058 2020
17
[Biochemical atypia in the modern russian strains of Neisseria gonorrhoeae.] 61
32762194 2020
18
US detection of medial meniscus extrusion can predict the risk of developing radiographic knee osteoarthritis: a 5-year cohort study. 61
32140818 2020
19
A short, animated video to improve good COVID-19 hygiene practices: a structured summary of a study protocol for a randomized controlled trial. 61
32493460 2020
20
Patient-Reported and Parent Proxy-Reported Outcomes in Pediatric Medical Specialty Clinical Settings: A Systematic Review of Implementation. 61
31710671 2020
21
Sulphur-based autotrophic denitrification of wastewater obtained following graphite production: Long-term performance, microbial communities involved, and functional gene analysis. 61
32169509 2020
22
Fiber-based HIC capture loop for coupling of protein A and size exclusion chromatography in a two-dimensional separation of monoclonal antibodies. 61
31948583 2020
23
Rapid two-dimensional Protein-A size exclusion chromatography of monoclonal antibodies for titer and aggregation measurements from harvested cell culture fluid samples. 61
31876441 2020
24
Gratitude Questionnaire-20 Items (G20): A Cross-Cultural, Psychometric and Crowdsourcing Analysis. 61
33408677 2020
25
PROA concept: prosthetic restoration with orthodontic appliance. 61
32128526 2020
26
Development of BioRad NGC and GE ÄKTA pure systems for highly automated three column protein purification employing tandem affinity, buffer exchange and size exclusion chromatography. 61
31499166 2020
27
Detection of thioredoxin-1 using ultra-sensitive ELISA with enzyme-encapsulated human serum albumin nanoparticle. 61
31814041 2019
28
Pectobacterium zantedeschiae sp. nov. a new species of a soft rot pathogen isolated from Calla lily (Zantedeschia spp.). 61
30885535 2019
29
Qualitative and quantitative characterization of sialylated N-glycans using three fluorophores, two columns, and two instrumentations. 61
30797744 2019
30
Evaluation of perceived quality in non-restrictive interventions within the antimicrobial stewardship program in pediatrics (PROA-NEN). 61
30606492 2019
31
Comparison of meniscal extrusion and osteophyte formation at the intercondylar notch as a predictive biomarker for incidence of knee osteoarthritis-Data from the Osteoarthritis Initiative. 61
30166083 2019
32
Analysis of quality antimicrobial agent use in the emergency department of a tertiary care hospital. 61
30260113 2018
33
Proscillaridin A exerts anti-tumor effects through GSK3β activation and alteration of microtubule dynamics in glioblastoma. 61
30250248 2018
34
Antimicrobial stewardship in Spain: Programs for Optimizing the use of Antibiotics (PROA) in Spanish hospitals. 61
30250829 2018
35
Thermodynamic and conformational analysis of the interaction between antibody binding proteins and IgG. 61
29410106 2018
36
Chemical modification of protein A chromatography ligands with polyethylene glycol. I: Effects on IgG adsorption equilibrium, kinetics, and transport. 61
29551236 2018
37
Chemical modification of protein a chromatography ligands with polyethylene glycol. II: Effects on resin robustness and process selectivity. 61
29551237 2018
38
Type II Secretion-Dependent Aminopeptidase LapA and Acyltransferase PlaC Are Redundant for Nutrient Acquisition during Legionella pneumophila Intracellular Infection of Amoebas. 61
29666285 2018
39
A third HSAN5 mutation disrupts the nerve growth factor furin cleavage site. 61
30296891 2018
40
Development of Biofortified Maize Hybrids through Marker-Assisted Stacking of β-Carotene Hydroxylase, Lycopene-ε-Cyclase and Opaque2 Genes. 61
29515602 2018
41
Molecular characterization of 5' UTR of the lycopene epsilon cyclase (lcyE) gene among exotic and indigenous inbreds for its utilization in maize biofortification. 61
29354386 2018
42
Comparison of 2-Aminobenzamide, Procainamide and RapiFluor-MS as Derivatizing Agents for High-Throughput HILIC-UPLC-FLR-MS N-glycan Analysis. 61
30094234 2018
43
Influence of Biochemical Features of Burkholderia pseudomallei Strains on Identification Reliability by Vitek 2 System. 61
29563716 2018
44
Disulfide loop cleavage of Legionella pneumophila PlaA boosts lysophospholipase A activity. 61
29176577 2017
45
Synthesis of the compatible solute proline by Bacillus subtilis: point mutations rendering the osmotically controlled proHJ promoter hyperactive. 61
28752945 2017
46
Polyclonal and monoclonal IgG binding on protein A resins-Evidence of competitive binding effects. 61
28294302 2017
47
Type II Secretion Substrates of Legionella pneumophila Translocate Out of the Pathogen-Occupied Vacuole via a Semipermeable Membrane. 61
28634242 2017
48
l-lysine production by Bacillus methanolicus: Genome-based mutational analysis and l-lysine secretion engineering. 61
28163092 2017
49
SymB and SymC, two membrane associated proteins, are required for Epichloë festucae hyphal cell-cell fusion and maintenance of a mutualistic interaction with Lolium perenne. 61
27882646 2017
50
The significance of proline and glutamate on butanol chaotropic stress in Bacillus subtilis 168. 61
28503197 2017

Variations for Proline-Negative Auxotroph of Hamster, Complementation of

Expression for Proline-Negative Auxotroph of Hamster, Complementation of

Search GEO for disease gene expression data for Proline-Negative Auxotroph of Hamster, Complementation of.

Pathways for Proline-Negative Auxotroph of Hamster, Complementation of

GO Terms for Proline-Negative Auxotroph of Hamster, Complementation of

Sources for Proline-Negative Auxotroph of Hamster, Complementation of

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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