MCID: PRP068
MIFTS: 12

Propriospinal Myoclonus

Categories: Rare diseases

Aliases & Classifications for Propriospinal Myoclonus

MalaCards integrated aliases for Propriospinal Myoclonus:

Name: Propriospinal Myoclonus 53

Classifications:



Summaries for Propriospinal Myoclonus

NIH Rare Diseases : 53 Propriospinal myoclonus (PSM) is a rare movement disorder first described in 1991. It is characterized by painless, repetitive jerking of the trunk, neck, hips, and knees. The jerking may be spontaneous but may also occur in response to a stimulus. The jerking often gets worse when the person is lying down. In some cases, a strange sensation such as a tingling at the back of the neck, a clicking sensation in the head, or an electrical current-like sensation may precede the jerks. Causes of PSM can include a spinal lesion, infection, or certain medications. In some cases, PSM is thought to have a psychogenic component. In most cases, the cause is not known (idiopathic). The work-up usually includes an MRI to rule out spinal lesions. No current guidelines regarding the treatment of PSM exist. Therapy includes treatment of any underlying disorders. Several medications have been tried with varying success, but larger controlled studies are needed to learn more.

MalaCards based summary : Propriospinal Myoclonus is related to myoclonus and apnea, obstructive sleep. An important gene associated with Propriospinal Myoclonus is LOC108684022 (FRAXA Repeat Instability Region).

Related Diseases for Propriospinal Myoclonus

Diseases related to Propriospinal Myoclonus via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 myoclonus 10.8
2 apnea, obstructive sleep 10.0
3 multiple sclerosis 10.0
4 fibrodysplasia ossificans progressiva 10.0
5 aging 10.0
6 arteriovenous fistula 10.0
7 restless legs syndrome 10.0
8 sleep apnea 10.0
9 cervicitis 10.0

Graphical network of the top 20 diseases related to Propriospinal Myoclonus:



Diseases related to Propriospinal Myoclonus

Symptoms & Phenotypes for Propriospinal Myoclonus

Drugs & Therapeutics for Propriospinal Myoclonus

Search Clinical Trials , NIH Clinical Center for Propriospinal Myoclonus

Genetic Tests for Propriospinal Myoclonus

Anatomical Context for Propriospinal Myoclonus

Publications for Propriospinal Myoclonus

Articles related to Propriospinal Myoclonus:

(show all 48)
# Title Authors Year
1
Elderly woman presenting with unusual propriospinal myoclonus triggered by drug-induced nausea and vomiting. ( 29542295 )
2018
2
Treatment of Propriospinal Myoclonus at Sleep Onset. ( 28516739 )
2017
3
Event related desynchronisation predicts functional propriospinal myoclonus. ( 27477621 )
2016
4
Desultory propriospinal myoclonus after epidural analgesia in a healthy parturient. ( 25840854 )
2015
5
A restless abdomen and propriospinal myoclonus like at sleep onset: an unusual overlap syndrome. ( 25820108 )
2015
6
Propriospinal myoclonus: Clinical reappraisal and review of literature. ( 25305154 )
2014
7
The pathophysiology of symptomatic propriospinal myoclonus. ( 24976412 )
2014
8
General anesthesia treatment of propriospinal myoclonus in a patient with fibrodysplasia ossificans progressiva. ( 25612266 )
2014
9
Postsurgical propriospinal myoclonus emerging at wake to sleep transition. ( 24238963 )
2014
10
Propriospinal myoclonus: where do we go from here? ( 24985526 )
2014
11
Propriospinal myoclonus: The spectrum of clinical and neurophysiological phenotypes. ( 25500332 )
2014
12
Propriospinal myoclonus: is it always psychogenic? ( 23901073 )
2013
13
Clinical diagnosis of propriospinal myoclonus is unreliable: an electrophysiologic study. ( 24105950 )
2013
14
Reversible propriospinal myoclonus due to thoracic disc herniation: long-term follow-up. ( 22014609 )
2012
15
Obstructive sleep apnea syndrome aggravated propriospinal myoclonus at sleep onset. ( 22033123 )
2012
16
Prolonged propriospinal myoclonus following spinal anesthesia for cesarean section: case report and literature review. ( 22302138 )
2012
17
Propriospinal myoclonus associated with gluten sensitivity in a young woman. ( 22225790 )
2012
18
A reappraisal of long-latency abdominal muscle reflexes in patients with propriospinal myoclonus. ( 21618608 )
2011
19
Propriospinal myoclonus associated with fragile-X-premutation and response to selective serotonin reuptake inhibitor. ( 21570890 )
2011
20
Propriospinal Myoclonus Induced by a Herniated Lumbar Intervertebral Disc at a Young Age: A Case Report. ( 26064150 )
2011
21
Propriospinal myoclonus following intrathecal bupivacaine in hip surgery: a case report. ( 20332743 )
2010
22
Propriospinal myoclonus due to cord compression in the absence of myelopathy. ( 20310008 )
2010
23
Propriospinal myoclonus in a child. ( 20197268 )
2010
24
Propriospinal myoclonus revisited: Clinical, neurophysiologic, and neuroradiologic findings. ( 19365051 )
2009
25
Propriospinal myoclonus at sleep onset causing severe insomnia: a polysomnographic and electromyographic analysis. ( 19230756 )
2009
26
TENS for the treatment of propriospinal myoclonus. ( 18823015 )
2008
27
Psychogenic propriospinal myoclonus. ( 18412285 )
2008
28
Propriospinal myoclonus: utility of magnetic resonance diffusion tensor imaging and fiber tracking. ( 17523193 )
2007
29
Propriospinal myoclonus: report of a case. ( 18220019 )
2007
30
Electromyography patterns of propriospinal myoclonus can be mimicked voluntarily. ( 16685694 )
2006
31
Propriospinal myoclonus at sleep onset. ( 17336781 )
2006
32
Propriospinal myoclonus with life threatening tonic spasms as paraneoplastic presentation of breast cancer. ( 16484662 )
2006
33
Propriospinal myoclonus due to cervical disc herniation. Case report. ( 15945438 )
2005
34
Case of symptomatic propriospinal myoclonus evolving toward acute "myoclonic status". ( 16092107 )
2005
35
Propriospinal myoclonus: a motor phenomenon found in restless legs syndrome different from periodic limb movements during sleep. ( 16007657 )
2005
36
Cannabis-induced propriospinal myoclonus. ( 15197714 )
2004
37
Propriospinal myoclonus after treatment with ciprofloxacin. ( 15133830 )
2004
38
Atypical propriospinal myoclonus with possible relationship to alpha interferon therapy. ( 14673903 )
2003
39
Unique form of propriospinal myoclonus as a possible complication of an enteropathogenic toxin. ( 12889087 )
2003
40
Propriospinal myoclonus at the sleep-wake transition: a new type of parasomnia. ( 11683486 )
2001
41
Propriospinal myoclonus in ischemic myelopathy secondary to a spinal dural arteriovenous fistula. ( 10752597 )
2000
42
Propriospinal myoclonus upon relaxation and drowsiness: a cause of severe insomnia. ( 8990056 )
1997
43
Lyme neuroborreliosis presenting with propriospinal myoclonus. ( 8890788 )
1996
44
Propriospinal myoclonus. ( 8891395 )
1995
45
Propriospinal myoclonus in tetraplegic patients: clinical, electrophysiological and therapeutic aspects. ( 8584305 )
1995
46
Propriospinal myoclonus: evidence for spinal "pattern" generators in humans. ( 7990853 )
1994
47
Propriospinal myoclonus in multiple sclerosis. ( 1469408 )
1992
48
Propriospinal myoclonus: a neurophysiologic analysis. ( 1641156 )
1992

Variations for Propriospinal Myoclonus

Expression for Propriospinal Myoclonus

Search GEO for disease gene expression data for Propriospinal Myoclonus.

Pathways for Propriospinal Myoclonus

GO Terms for Propriospinal Myoclonus

Sources for Propriospinal Myoclonus

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69 SNOMED-CT via HPO
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71 TGDB
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74 UMLS via Orphanet
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