Prostate Adenoid Cystic Carcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Prostate Adenoid Cystic Carcinoma

MalaCards integrated aliases for Prostate Adenoid Cystic Carcinoma:

Name: Prostate Adenoid Cystic Carcinoma ¹² ¹⁵ ⁷⁰

Adenoid Cystic Carcinoma of the Prostate ¹²

Adenoid Cystic Carcinoma of Prostate ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:4868

NCIt ⁵⁰ C5539

UMLS ⁷⁰ C1335502

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Summaries for Prostate Adenoid Cystic Carcinoma

MalaCards based summary : Prostate Adenoid Cystic Carcinoma, also known as adenoid cystic carcinoma of the prostate, is related to nodular prostate and prostatic hyperplasia, benign, and has symptoms including pain An important gene associated with Prostate Adenoid Cystic Carcinoma is KLK3 (Kallikrein Related Peptidase 3), and among its related pathways/superpathways are Translation Non-genomic (rapid) action of Androgen Receptor and Androgen receptor signaling pathway. Affiliated tissues include prostate.

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Related Diseases for Prostate Adenoid Cystic Carcinoma

Diseases related to Prostate Adenoid Cystic Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 44)

#	Related Disease	Score	Top Affiliating Genes
1	nodular prostate	30.2	KLK3 AR
2	prostatic hyperplasia, benign	30.2	KLK3 AR
3	prostatic adenoma	30.2	KLK3 AR
4	prostatic hypertrophy	30.2	KLK3 AR
5	suppression of tumorigenicity 12	30.1	KLK3 AR
6	urinary tract obstruction	10.3
7	rare tumor	10.3
8	transitional cell carcinoma	10.2
9	adenocarcinoma	10.2
10	adenoid cystic carcinoma	10.1
11	prostate leiomyoma	10.0	KLK3 AR
12	prostate calculus	10.0	KLK3 AR
13	bronchiectasis 3	10.0	KLK3 AR
14	prostatic acinar adenocarcinoma	10.0	KLK3 AR
15	prostate neuroendocrine neoplasm	10.0	KLK3 AR
16	prostate transitional cell carcinoma	10.0	KLK3 AR
17	male reproductive organ benign neoplasm	9.9	KLK3 AR
18	androgenic alopecia	9.9	KLK3 AR
19	lymph node carcinoma	9.9	KLK3 AR
20	female breast cancer	9.9	KLK3 AR
21	small cell carcinoma	9.9	KLK3 AR
22	male reproductive organ cancer	9.9	KLK3 AR
23	prostate disease	9.8	KLK3 AR
24	sebaceous gland disease	9.8	POMC AR
25	male reproductive system disease	9.8	KLK3 AR
26	disorder of sexual development	9.8	POMC AR
27	aromatase excess syndrome	9.8	POMC AR
28	tuberculous epididymitis	9.8	POMC KLK3
29	hair disease	9.8	POMC AR
30	hyperandrogenism	9.8	POMC AR
31	pseudohermaphroditism	9.8	POMC AR
32	acne	9.8	POMC AR
33	46,xy sex reversal	9.8	POMC AR
34	cryptorchidism, unilateral or bilateral	9.8	POMC AR
35	impotence	9.8	POMC KLK3
36	ovarian disease	9.7	POMC AR
37	breast disease	9.6	POMC KLK3
38	amelogenesis imperfecta	9.6	POMC AR
39	prader-willi syndrome	9.6	POMC AR
40	withdrawal disorder	9.5	POMC KLK3 AR
41	sexual disorder	9.5	POMC KLK3 AR
42	gynecomastia	9.5	POMC KLK3 AR
43	skin carcinoma	9.5	POMC KLK3 AR
44	premature menopause	9.5	POMC AR

Graphical network of the top 20 diseases related to Prostate Adenoid Cystic Carcinoma:

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Symptoms & Phenotypes for Prostate Adenoid Cystic Carcinoma

UMLS symptoms related to Prostate Adenoid Cystic Carcinoma:

pain

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Drugs & Therapeutics for Prostate Adenoid Cystic Carcinoma

Search Clinical Trials , NIH Clinical Center for Prostate Adenoid Cystic Carcinoma

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Genetic Tests for Prostate Adenoid Cystic Carcinoma

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Anatomical Context for Prostate Adenoid Cystic Carcinoma

MalaCards organs/tissues related to Prostate Adenoid Cystic Carcinoma:

⁴⁰

Prostate

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Publications for Prostate Adenoid Cystic Carcinoma

Articles related to Prostate Adenoid Cystic Carcinoma:

(show all 22)

#	Title	Authors	PMID	Year
1	Adenoid cystic carcinoma of the prostate: case report on a rare entity and review of the literature. ⁶¹	Ahuja A...Ray R	21440997	2011
2	Basal cell carcinoma of the prostate: a clinicopathologic study of 29 cases. ⁶¹	Ali TZ...Epstein JI	17460452	2007
3	Asynchronous adenoid cystic carcinoma of the prostate and transitional cell carcinoma of the urinary bladder. ⁶¹	Fayyad LM...Al-Hawwari BA	16830032	2006
4	[Adenoid cystic carcinoma of the prostate]. ⁶¹	Palazzo C...Costa M	15714854	2004
5	Late recurrence of adenoid cystic carcinoma of the prostate. ⁶¹	Schmid HP...Hertle L	12028693	2002
6	Adenoid cystic carcinoma of the prostate: a case report with immunohistochemical and in situ hybridization staining for prostate-specific antigen. ⁶¹	Minei S...Okada K	11555019	2001
7	[Adenoid cystic carcinoma of the prostate. Clinical case]. ⁶¹	Cecchi M...Fiorentini L	11085064	2000
8	The appearance of adenoid cystic carcinoma of the prostate on transrectal ultrasonography. ⁶¹	Terris MK	10368222	1999
9	[Adenoid cystic carcinoma of the prostate. A case report]. ⁶¹	Shindo M...Ikeda E	9739589	1998
10	[Cystic adenoid carcinoma of the prostate. Report of a case]. ⁶¹	Osorio Acosta V...Borrajero Martinez I	9182493	1997
11	Adenoid cystic carcinoma of the prostate. ⁶¹	van Renterghem K...Billiet I	7976858	1994
12	Atypical basal cell hyperplasia of the prostate. ⁶¹	Epstein JI...Armas OA	1281386	1992
13	Adenoid cystic carcinoma of the prostate gland--pathological review with a case report. ⁶¹	Ahn SK...Lee JM	1652178	1991
14	Unusual prostatic carcinomas. ⁶¹	Dhom G	2179908	1990
15	Basal cell hyperplasia, adenoid basal cell tumor, and adenoid cystic carcinoma of the prostate gland: an immunohistochemical study. ⁶¹	Grignon DJ...Cleary KR	2461340	1988
16	Adenoid cystic carcinoma of the prostate. ⁶¹	Nkanza NK	2855041	1988
17	Adenoid cystic-like tumor of the prostate gland. A report of two cases and review of the literature on "adenoid cystic carcinoma" of the prostate. ⁶¹	Young RH...Bhan AK	2827457	1988
18	Adenoid cystic carcinoma of the prostate. ⁶¹	Gilmour AM...Bell TJ	3004625	1986
19	Adenoid cystic carcinoma of prostate. Report of a case. ⁶¹	Chan SS...Walters MN	6096795	1984
20	Adenoid cystic carcinoma of the prostate. A case report with immunoperoxidase staining for prostate-specific acid phosphatase and prostate-specific antigen. ⁶¹	Kuhajda FP...Mann RB	6198901	1984
21	Adenoid cystic carcinoma of the prostate: report of a case. ⁶¹	Kramer SA...Krueger RP	682268	1978
22	Adenoid cystic carcinoma of the prostate. Report of a case. ⁶¹	Frankel K...Craig JR	4137525	1974

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Genes for Prostate Adenoid Cystic Carcinoma

Genes related to Prostate Adenoid Cystic Carcinoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	KLK3	Kallikrein Related Peptidase 3	Protein Coding	6.01	DISEASES inferred ¹⁵
2	POMC	Proopiomelanocortin	Protein Coding	4.49	DISEASES inferred ¹⁵
3	AR	Androgen Receptor	Protein Coding	3.35	DISEASES inferred ¹⁵

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Variations for Prostate Adenoid Cystic Carcinoma

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Expression for Prostate Adenoid Cystic Carcinoma

Search GEO for disease gene expression data for Prostate Adenoid Cystic Carcinoma.

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Pathways for Prostate Adenoid Cystic Carcinoma

Pathways related to Prostate Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Translation Non-genomic (rapid) action of Androgen Receptor ²³ Show member pathways Basal cell carcinoma ³⁶ Transcription Androgen Receptor nuclear signaling ²³	11.64	KLK3 AR
2	Androgen receptor signaling pathway ¹	11.22	KLK3 AR
3	Coregulation of Androgen receptor activity ¹	10.91	KLK3 AR
4	Regulation of Androgen receptor activity ¹	10.65	KLK3 AR
5	FOXA1 transcription factor network ¹ Show member pathways FOXA transcription factor networks ¹	10.29	KLK3 AR

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GO Terms for Prostate Adenoid Cystic Carcinoma

Cellular components related to Prostate Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	secretory granule	GO:0030141	8.62	POMC KLK3

Biological processes related to Prostate Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cell-cell signaling	GO:0007267	8.96	POMC AR
2	regulation of systemic arterial blood pressure	GO:0003073	8.62	KLK3 AR

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