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MCID: PRS019
MIFTS: 25

Prostate Adenoid Cystic Carcinoma

Categories: Cancer diseases, Reproductive diseases
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Aliases & Classifications for Prostate Adenoid Cystic Carcinoma

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MalaCards integrated aliases for Prostate Adenoid Cystic Carcinoma:

Name: Prostate Adenoid Cystic Carcinoma 11 14 71
Adenoid Cystic Carcinoma of the Prostate 11
Adenoid Cystic Carcinoma of Prostate 11

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 11 DOID:4868
NCIt 49 C5539
UMLS 71 C1335502
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Summaries for Prostate Adenoid Cystic Carcinoma

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MalaCards based summary: Prostate Adenoid Cystic Carcinoma, also known as adenoid cystic carcinoma of the prostate, is related to prostatic hyperplasia, benign and suppression of tumorigenicity 12, and has symptoms including pain An important gene associated with Prostate Adenoid Cystic Carcinoma is KLK3 (Kallikrein Related Peptidase 3), and among its related pathways/superpathways are Signal Transduction and Integrated breast cancer pathway. Affiliated tissues include prostate, and related phenotypes are Increased shRNA abundance (Z-score > 2) and pigmentation
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Related Diseases for Prostate Adenoid Cystic Carcinoma

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Diseases related to Prostate Adenoid Cystic Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 61)
# Related Disease Score Top Affiliating Genes
1 prostatic hyperplasia, benign 30.3 KLK3 AR
2 suppression of tumorigenicity 12 30.2 KLK3 AR
3 transitional cell carcinoma 29.8 KLK3 BCL2
4 urinary tract obstruction 10.3
5 rare tumor 10.3
6 factor vii deficiency 10.2
7 nodular prostate 10.2
8 urethral syndrome 10.2
9 basal cell carcinoma 10.2
10 adenocarcinoma 10.2
11 prostate cancer 10.1
12 adenoid cystic carcinoma 10.1
13 prostate leiomyoma 10.0 KLK3 AR
14 prostate calculus 10.0 KLK3 AR
15 prostatic acinar adenocarcinoma 10.0 KLK3 AR
16 prostate small cell carcinoma 10.0 KLK3 AR
17 prostate neuroendocrine neoplasm 10.0 KLK3 AR
18 castration-resistant prostate carcinoma 10.0 KLK3 AR
19 male reproductive organ benign neoplasm 10.0 KLK3 AR
20 prostatic adenoma 10.0 KLK3 AR
21 prostatic hypertrophy 10.0 KLK3 AR
22 primary cutaneous amyloidosis 10.0 KLK3 AR
23 lymph node carcinoma 10.0 KLK3 AR
24 tuberculous epididymitis 10.0 POMC KLK3
25 17-beta hydroxysteroid dehydrogenase iii deficiency 9.9 POMC AR
26 aromatase excess syndrome 9.9 POMC AR
27 sebaceous gland disease 9.9 POMC AR
28 impotence 9.9 KLK3 AR
29 hair disease 9.9 POMC AR
30 pseudohermaphroditism 9.9 POMC AR
31 hyperandrogenism 9.9 POMC AR
32 acne 9.9 POMC AR
33 46,xy sex reversal 9.9 POMC AR
34 lipoid congenital adrenal hyperplasia 9.9 POMC AR
35 disorder of sexual development 9.8 POMC AR
36 estrogen-receptor negative breast cancer 9.8 BCL2 AR
37 estrogen-receptor positive breast cancer 9.8 BCL2 AR
38 varicocele 9.8 BCL2 AR
39 amelogenesis imperfecta, type ig 9.8 BCL2 AR
40 endometrial hyperplasia 9.8 BCL2 AR
41 intracranial hypertension 9.8 POMC BCL2
42 cryptorchidism, unilateral or bilateral 9.8 POMC AR
43 polycystic ovary syndrome 9.7 POMC AR
44 breast ductal carcinoma 9.7 BCL2 AR
45 withdrawal disorder 9.7 POMC KLK3 AR
46 gynecomastia 9.7 POMC KLK3 AR
47 inguinal hernia 9.7 POMC KLK3 AR
48 acquired immunodeficiency syndrome 9.7 POMC BCL2
49 hypogonadism 9.7 POMC KLK3 AR
50 female breast cancer 9.6 KLK3 BCL2 AR

Graphical network of the top 20 diseases related to Prostate Adenoid Cystic Carcinoma:



Diseases related to Prostate Adenoid Cystic Carcinoma
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Symptoms & Phenotypes for Prostate Adenoid Cystic Carcinoma

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UMLS symptoms related to Prostate Adenoid Cystic Carcinoma:


pain

GenomeRNAi Phenotypes related to Prostate Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

25 (show all 16)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-102 9.85 POMC
2 Increased shRNA abundance (Z-score > 2) GR00366-A-106 9.85 BCL2
3 Increased shRNA abundance (Z-score > 2) GR00366-A-134 9.85 BCL2
4 Increased shRNA abundance (Z-score > 2) GR00366-A-159 9.85 BCL2
5 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.85 BCL2
6 Increased shRNA abundance (Z-score > 2) GR00366-A-194 9.85 BCL2
7 Increased shRNA abundance (Z-score > 2) GR00366-A-199 9.85 BCL2
8 Increased shRNA abundance (Z-score > 2) GR00366-A-210 9.85 BCL2
9 Increased shRNA abundance (Z-score > 2) GR00366-A-32 9.85 POMC
10 Increased shRNA abundance (Z-score > 2) GR00366-A-37 9.85 BCL2
11 Increased shRNA abundance (Z-score > 2) GR00366-A-59 9.85 BCL2
12 Increased shRNA abundance (Z-score > 2) GR00366-A-68 9.85 BCL2
13 Increased shRNA abundance (Z-score > 2) GR00366-A-70 9.85 BCL2
14 Increased shRNA abundance (Z-score > 2) GR00366-A-77 9.85 BCL2
15 Increased shRNA abundance (Z-score > 2) GR00366-A-88 9.85 BCL2 POMC
16 Increased shRNA abundance (Z-score > 2) GR00366-A-96 9.85 BCL2

MGI Mouse Phenotypes related to Prostate Adenoid Cystic Carcinoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 pigmentation MP:0001186 9.13 AR BCL2 POMC
2 neoplasm MP:0002006 8.8 AR BCL2 POMC
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Drugs & Therapeutics for Prostate Adenoid Cystic Carcinoma

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Search Clinical Trials, NIH Clinical Center for Prostate Adenoid Cystic Carcinoma

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Genetic Tests for Prostate Adenoid Cystic Carcinoma

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Anatomical Context for Prostate Adenoid Cystic Carcinoma

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Organs/tissues related to Prostate Adenoid Cystic Carcinoma:

MalaCards : Prostate
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Publications for Prostate Adenoid Cystic Carcinoma

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Articles related to Prostate Adenoid Cystic Carcinoma:

(show all 23)
# Title Authors PMID Year
1
Adenoid cystic carcinoma of the prostate - A rare case of genitourinary malignancy. 62
35530540 2022
2
Adenoid cystic carcinoma of the prostate: case report on a rare entity and review of the literature. 62
21440997 2011
3
Basal cell carcinoma of the prostate: a clinicopathologic study of 29 cases. 62
17460452 2007
4
Asynchronous adenoid cystic carcinoma of the prostate and transitional cell carcinoma of the urinary bladder. 62
16830032 2006
5
[Adenoid cystic carcinoma of the prostate]. 62
15714854 2004
6
Late recurrence of adenoid cystic carcinoma of the prostate. 62
12028693 2002
7
Adenoid cystic carcinoma of the prostate: a case report with immunohistochemical and in situ hybridization staining for prostate-specific antigen. 62
11555019 2001
8
[Adenoid cystic carcinoma of the prostate. Clinical case]. 62
11085064 2000
9
The appearance of adenoid cystic carcinoma of the prostate on transrectal ultrasonography. 62
10368222 1999
10
[Adenoid cystic carcinoma of the prostate. A case report]. 62
9739589 1998
11
[Cystic adenoid carcinoma of the prostate. Report of a case]. 62
9182493 1997
12
Adenoid cystic carcinoma of the prostate. 62
7976858 1994
13
Atypical basal cell hyperplasia of the prostate. 62
1281386 1992
14
Adenoid cystic carcinoma of the prostate gland--pathological review with a case report. 62
1652178 1991
15
Unusual prostatic carcinomas. 62
2179908 1990
16
Basal cell hyperplasia, adenoid basal cell tumor, and adenoid cystic carcinoma of the prostate gland: an immunohistochemical study. 62
2461340 1988
17
Adenoid cystic carcinoma of the prostate. 62
2855041 1988
18
Adenoid cystic-like tumor of the prostate gland. A report of two cases and review of the literature on "adenoid cystic carcinoma" of the prostate. 62
2827457 1988
19
Adenoid cystic carcinoma of the prostate. 62
3004625 1986
20
Adenoid cystic carcinoma of prostate. Report of a case. 62
6096795 1984
21
Adenoid cystic carcinoma of the prostate. A case report with immunoperoxidase staining for prostate-specific acid phosphatase and prostate-specific antigen. 62
6198901 1984
22
Adenoid cystic carcinoma of the prostate: report of a case. 62
682268 1978
23
Adenoid cystic carcinoma of the prostate. Report of a case. 62
4137525 1974
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Variations for Prostate Adenoid Cystic Carcinoma

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Expression for Prostate Adenoid Cystic Carcinoma

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Search GEO for disease gene expression data for Prostate Adenoid Cystic Carcinoma.
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Pathways for Prostate Adenoid Cystic Carcinoma

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Pathways related to Prostate Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Signal Transduction 66
13.08 POMC KLK3 BCL2 AR
2
Integrated breast cancer pathway 74
11.64 BCL2 AR
3
Transcription Androgen Receptor nuclear signaling 22
Show member pathways
 11.6 KLK3 AR
4
Interleukin-4 and Interleukin-13 signaling 66
11.44 POMC BCL2
5
Corticotropin-releasing hormone signaling pathway 74
11.28 POMC BCL2
6
Coregulation of Androgen receptor activity 61
11.04 KLK3 AR
7
Regulation of Androgen receptor activity 61
10.85 KLK3 AR
8
Melanocyte Development and Pigmentation 64
10.57 POMC BCL2
9
FOXA1 transcription factor network 61
10.19 KLK3 AR
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GO Terms for Prostate Adenoid Cystic Carcinoma

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Cellular components related to Prostate Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 secretory granule GO:0030141 8.92 POMC KLK3

Biological processes related to Prostate Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 male gonad development GO:0008584 9.26 BCL2 AR
2 regulation of systemic arterial blood pressure GO:0003073 8.92 KLK3 AR
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Sources for Prostate Adenoid Cystic Carcinoma

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2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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