MCID: PRS005
MIFTS: 23

Prostate Angiosarcoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Prostate Angiosarcoma

MalaCards integrated aliases for Prostate Angiosarcoma:

Name: Prostate Angiosarcoma 12 15 71
Prostatic Hemangiosarcoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4524
NCIt 49 C5528
UMLS 71 C1335504

Summaries for Prostate Angiosarcoma

Disease Ontology : 12 An angiosarcoma and sarcoma of prostate that is located in the prostate.

MalaCards based summary : Prostate Angiosarcoma, also known as prostatic hemangiosarcoma, is related to angiosarcoma and suppression of tumorigenicity 12. An important gene associated with Prostate Angiosarcoma is PECAM1 (Platelet And Endothelial Cell Adhesion Molecule 1), and among its related pathways/superpathways are Cell adhesion molecules (CAMs) and Fluid shear stress and atherosclerosis. Affiliated tissues include prostate, heart and breast.

Related Diseases for Prostate Angiosarcoma

Diseases related to Prostate Angiosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 110)
# Related Disease Score Top Affiliating Genes
1 angiosarcoma 29.3 VEGFA PECAM1 CD34
2 suppression of tumorigenicity 12 29.2 VEGFA PECAM1
3 leiomyosarcoma 10.0 VEGFA PECAM1
4 acquired hemangioma 10.0 VEGFA PECAM1
5 radiation proctitis 10.0 VEGFA PECAM1
6 proctitis 10.0 VEGFA PECAM1
7 juvenile nasopharyngeal angiofibroma 10.0 VEGFA PECAM1
8 hydrocele 9.9 VEGFA PECAM1
9 corneal neovascularization 9.9 VEGFA PECAM1
10 keratitis, hereditary 9.9 VEGFA PECAM1
11 arteriovenous malformations of the brain 9.9 VEGFA PECAM1
12 hemoglobinopathy 9.9 VEGFA PECAM1
13 exudative vitreoretinopathy 1 9.8 VEGFA PECAM1
14 corneal disease 9.8 VEGFA PECAM1
15 infiltrating angiolipoma 9.8 VEGFA CD34
16 breast leiomyosarcoma 9.8 VEGFA CD34
17 skin epithelioid hemangioma 9.8 PECAM1 CD34
18 central nervous system angiosarcoma 9.8 PECAM1 CD34
19 intravascular angioleiomyoma 9.8 PECAM1 CD34
20 heart fibrosarcoma 9.8 PECAM1 CD34
21 central nervous system hemangioma 9.8 PECAM1 CD34
22 ovarian angiosarcoma 9.8 PECAM1 CD34
23 spindle cell sarcoma 9.8 VEGFA CD34
24 conventional angiosarcoma 9.8 PECAM1 CD34
25 angiomyoma 9.8 PECAM1 CD34
26 aortic malignant tumor 9.8 PECAM1 CD34
27 gallbladder leiomyosarcoma 9.8 PECAM1 CD34
28 hemangioma of spleen 9.8 PECAM1 CD34
29 ovary sarcoma 9.8 PECAM1 CD34
30 heart leiomyosarcoma 9.8 PECAM1 CD34
31 colonic lymphangioma 9.8 PECAM1 CD34
32 benign perivascular tumor 9.8 PECAM1 CD34
33 liposarcoma of bone 9.8 PECAM1 CD34
34 kaposiform hemangioendothelioma 9.8 PECAM1 CD34
35 intravascular fasciitis 9.8 PECAM1 CD34
36 erythema elevatum diutinum 9.8 PECAM1 CD34
37 hepatic vascular disease 9.8 VEGFA CD34
38 liver leiomyoma 9.8 PECAM1 CD34
39 spleen cancer 9.8 PECAM1 CD34
40 uterine benign neoplasm 9.8 VEGFA CD34
41 hobnail hemangioma 9.8 PECAM1 CD34
42 breast hemangioma 9.8 PECAM1 CD34
43 breast angiosarcoma 9.8 PECAM1 CD34
44 blood protein disease 9.8 VEGFA CD34
45 heart sarcoma 9.8 PECAM1 CD34
46 reproductive organ benign neoplasm 9.8 VEGFA CD34
47 vulvar leiomyoma 9.8 PECAM1 CD34
48 skin sarcoma 9.8 PECAM1 CD34
49 benign mesothelioma 9.8 PECAM1 CD34
50 bacillary angiomatosis 9.8 PECAM1 CD34

Graphical network of the top 20 diseases related to Prostate Angiosarcoma:



Diseases related to Prostate Angiosarcoma

Symptoms & Phenotypes for Prostate Angiosarcoma

Drugs & Therapeutics for Prostate Angiosarcoma

Search Clinical Trials , NIH Clinical Center for Prostate Angiosarcoma

Genetic Tests for Prostate Angiosarcoma

Anatomical Context for Prostate Angiosarcoma

The Foundational Model of Anatomy Ontology organs/tissues related to Prostate Angiosarcoma:

19
Prostate

MalaCards organs/tissues related to Prostate Angiosarcoma:

40
Prostate, Heart, Breast, Bone, Spleen, Skin, Bone Marrow

Publications for Prostate Angiosarcoma

Articles related to Prostate Angiosarcoma:

# Title Authors PMID Year
1
Angiosarcoma of the prostate: a more frequent finding in the future owing to radiotherapy? A literature review with treatment implications based on a case report. 61
24730474 2014
2
Prostate angiosarcoma: is there any association with previous radiation therapy? 61
22583810 2012
3
Prostate angiosarcoma: a case report and literature review. 61
22351253 2012
4
[Prostatic angiosarcoma: report of a new case]. 61
11284376 2001
5
Prostatic hemangiosarcoma in a dog: clinical and pathologic findings. 61
1616992 1992

Variations for Prostate Angiosarcoma

Expression for Prostate Angiosarcoma

Search GEO for disease gene expression data for Prostate Angiosarcoma.

Pathways for Prostate Angiosarcoma

Pathways related to Prostate Angiosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.12 PECAM1 CD34
2 10.77 VEGFA PECAM1

GO Terms for Prostate Angiosarcoma

Cellular components related to Prostate Angiosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell periphery GO:0071944 8.62 PECAM1 CD34

Biological processes related to Prostate Angiosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 leukocyte migration GO:0050900 9.43 PECAM1 CD34
2 positive regulation of protein phosphorylation GO:0001934 9.4 VEGFA PECAM1
3 cell-cell adhesion GO:0098609 9.37 PECAM1 CD34
4 positive regulation of angiogenesis GO:0045766 9.32 VEGFA CD34
5 platelet degranulation GO:0002576 9.26 VEGFA PECAM1
6 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.16 VEGFA PECAM1
7 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 8.96 VEGFA PECAM1
8 glomerular endothelium development GO:0072011 8.62 PECAM1 CD34

Sources for Prostate Angiosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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