MCID: PRS007
MIFTS: 22

Prostate Calculus

Categories: Reproductive diseases

Aliases & Classifications for Prostate Calculus

MalaCards integrated aliases for Prostate Calculus:

Name: Prostate Calculus 12 15
Calculus of Prostate 12 73
Prostatic Lithiasis 12
Stone of Prostate 12
Prostatic Stone 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13689
ICD10 33 N42.0
ICD9CM 35 602.0
NCIt 50 C26936
SNOMED-CT 68 85324003 95592006
UMLS 73 C0149525

Summaries for Prostate Calculus

MalaCards based summary : Prostate Calculus, also known as calculus of prostate, is related to alkaptonuria and ochronosis. An important gene associated with Prostate Calculus is HPD (4-Hydroxyphenylpyruvate Dioxygenase), and among its related pathways/superpathways are Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways and Integrated Breast Cancer Pathway. Affiliated tissues include prostate, and related phenotypes are Decreased caspase 3/7 activity and renal/urinary system

Related Diseases for Prostate Calculus

Diseases related to Prostate Calculus via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)
# Related Disease Score Top Affiliating Genes
1 alkaptonuria 32.3 HGD HPD
2 ochronosis 9.9 HGD HPD
3 ehrlichiosis 9.9 CASP3 HGD
4 bladder disease 9.9
5 neurogenic bladder 9.9
6 male reproductive organ cancer 9.8 AR CASP3
7 male reproductive system disease 9.8 AR CASP3
8 reproductive system disease 9.8 AR CASP3
9 prostatitis 9.8
10 endocrine gland cancer 9.8 AR CASP3
11 bladder urothelial carcinoma 9.7 AR CASP3
12 lower urinary tract calculus 9.6 AR HGD HPD

Comorbidity relations with Prostate Calculus via Phenotypic Disease Network (PDN):


Bladder Neck Obstruction Prostate Cancer
Prostatic Hypertrophy Prostatitis
Urethral Stricture Urinary Tract Obstruction

Graphical network of the top 20 diseases related to Prostate Calculus:



Diseases related to Prostate Calculus

Symptoms & Phenotypes for Prostate Calculus

GenomeRNAi Phenotypes related to Prostate Calculus according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased caspase 3/7 activity GR00318-A 8.8 AR CASP3 HGD

MGI Mouse Phenotypes related to Prostate Calculus:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 renal/urinary system MP:0005367 8.92 AR CASP3 HGD HPD

Drugs & Therapeutics for Prostate Calculus

Search Clinical Trials , NIH Clinical Center for Prostate Calculus

Genetic Tests for Prostate Calculus

Anatomical Context for Prostate Calculus

MalaCards organs/tissues related to Prostate Calculus:

41
Prostate

Publications for Prostate Calculus

Variations for Prostate Calculus

Expression for Prostate Calculus

Search GEO for disease gene expression data for Prostate Calculus.

Pathways for Prostate Calculus

GO Terms for Prostate Calculus

Biological processes related to Prostate Calculus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 L-phenylalanine catabolic process GO:0006559 8.96 HGD HPD
2 tyrosine catabolic process GO:0006572 8.62 HGD HPD

Molecular functions related to Prostate Calculus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 dioxygenase activity GO:0051213 8.62 HGD HPD

Sources for Prostate Calculus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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