MCID: PRS131
MIFTS: 14

Prostate Cancer/brain Cancer Susceptibility

Categories: Genetic diseases, Neuronal diseases, Cancer diseases

Aliases & Classifications for Prostate Cancer/brain Cancer Susceptibility

MalaCards integrated aliases for Prostate Cancer/brain Cancer Susceptibility:

Name: Prostate Cancer/brain Cancer Susceptibility 57 29 6 40
Prostate Cancer/brain Cancer Susceptibility, Somatic 57
Pcbc 57
Capb 57

Classifications:



External Ids:

OMIM 57 603688
MedGen 42 C1863600
SNOMED-CT via HPO 69 399068003 126951006

Summaries for Prostate Cancer/brain Cancer Susceptibility

MalaCards based summary : Prostate Cancer/brain Cancer Susceptibility, is also known as prostate cancer/brain cancer susceptibility, somatic. An important gene associated with Prostate Cancer/brain Cancer Susceptibility is EPHB2 (EPH Receptor B2). Affiliated tissues include prostate and brain, and related phenotypes are prostate cancer and neoplasm of the central nervous system

Description from OMIM: 603688

Related Diseases for Prostate Cancer/brain Cancer Susceptibility

Symptoms & Phenotypes for Prostate Cancer/brain Cancer Susceptibility

Clinical features from OMIM:

603688

Human phenotypes related to Prostate Cancer/brain Cancer Susceptibility:

32
# Description HPO Frequency HPO Source Accession
1 prostate cancer 32 HP:0012125
2 neoplasm of the central nervous system 32 HP:0100006

Drugs & Therapeutics for Prostate Cancer/brain Cancer Susceptibility

Search Clinical Trials , NIH Clinical Center for Prostate Cancer/brain Cancer Susceptibility

Genetic Tests for Prostate Cancer/brain Cancer Susceptibility

Genetic tests related to Prostate Cancer/brain Cancer Susceptibility:

# Genetic test Affiliating Genes
1 Prostate Cancer/brain Cancer Susceptibility 29 EPHB2

Anatomical Context for Prostate Cancer/brain Cancer Susceptibility

MalaCards organs/tissues related to Prostate Cancer/brain Cancer Susceptibility:

41
Prostate, Brain

Publications for Prostate Cancer/brain Cancer Susceptibility

Variations for Prostate Cancer/brain Cancer Susceptibility

ClinVar genetic disease variations for Prostate Cancer/brain Cancer Susceptibility:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 EPHB2 NM_004442.7(EPHB2): c.2167C> T (p.Gln723Ter) single nucleotide variant Pathogenic rs121912582 GRCh37 Chromosome 1, 23234473: 23234473
2 EPHB2 NM_004442.7(EPHB2): c.2167C> T (p.Gln723Ter) single nucleotide variant Pathogenic rs121912582 GRCh38 Chromosome 1, 22907980: 22907980
3 EPHB2 NM_004442.7(EPHB2): c.835G> T (p.Ala279Ser) single nucleotide variant Pathogenic rs35882952 GRCh37 Chromosome 1, 23189553: 23189553
4 EPHB2 NM_004442.7(EPHB2): c.835G> T (p.Ala279Ser) single nucleotide variant Pathogenic rs35882952 GRCh38 Chromosome 1, 22863060: 22863060
5 EPHB2 NM_004442.7(EPHB2): c.2035G> A (p.Asp679Asn) single nucleotide variant Pathogenic rs28936395 GRCh37 Chromosome 1, 23233346: 23233346
6 EPHB2 NM_004442.7(EPHB2): c.2035G> A (p.Asp679Asn) single nucleotide variant Pathogenic rs28936395 GRCh38 Chromosome 1, 22906853: 22906853
7 EPHB2 NM_001309193.1(EPHB2): c.3055A> T (p.Lys1019Ter) single nucleotide variant risk factor rs76826147 GRCh37 Chromosome 1, 23240250: 23240250
8 EPHB2 NM_001309193.1(EPHB2): c.3055A> T (p.Lys1019Ter) single nucleotide variant risk factor rs76826147 GRCh38 Chromosome 1, 22913757: 22913757

Expression for Prostate Cancer/brain Cancer Susceptibility

Search GEO for disease gene expression data for Prostate Cancer/brain Cancer Susceptibility.

Pathways for Prostate Cancer/brain Cancer Susceptibility

GO Terms for Prostate Cancer/brain Cancer Susceptibility

Sources for Prostate Cancer/brain Cancer Susceptibility

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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