HPC1
MCID: PRS097
MIFTS: 39

Prostate Cancer, Hereditary, 1 (HPC1)

Categories: Cancer diseases, Genetic diseases, Rare diseases, Reproductive diseases

Aliases & Classifications for Prostate Cancer, Hereditary, 1

MalaCards integrated aliases for Prostate Cancer, Hereditary, 1:

Name: Prostate Cancer, Hereditary, 1 57 73 29 54 6
Prostate Cancer 1 57 13
Prca1 57 73
Hpc1 57 73
Cancer, Prostate, Hereditary, Type 1 39
Familial Prostate Cancer 1 73
Prostate Cancer, Familial 71

Characteristics:

OMIM®:

57 (Updated 05-Mar-2021)
Inheritance:
autosomal dominant form


HPO:

31
prostate cancer, hereditary, 1:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

OMIM® 57 601518
MeSH 44 D011471
UMLS 71 C2931456

Summaries for Prostate Cancer, Hereditary, 1

UniProtKB/Swiss-Prot : 73 Prostate cancer, hereditary, 1: A condition associated with familial predisposition to cancer of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma.

MalaCards based summary : Prostate Cancer, Hereditary, 1, also known as prostate cancer 1, is related to prostate cancer and prostate cancer, hereditary, 2. An important gene associated with Prostate Cancer, Hereditary, 1 is RNASEL (Ribonuclease L). The drug Ethanol has been mentioned in the context of this disorder. Affiliated tissues include prostate, thyroid and breast, and related phenotypes are neoplasm and prostate cancer

More information from OMIM: 601518

Related Diseases for Prostate Cancer, Hereditary, 1

Graphical network of the top 20 diseases related to Prostate Cancer, Hereditary, 1:



Diseases related to Prostate Cancer, Hereditary, 1

Symptoms & Phenotypes for Prostate Cancer, Hereditary, 1

Human phenotypes related to Prostate Cancer, Hereditary, 1:

31
# Description HPO Frequency HPO Source Accession
1 neoplasm 31 HP:0002664
2 prostate cancer 31 HP:0012125

Symptoms via clinical synopsis from OMIM®:

57 (Updated 05-Mar-2021)
Oncology:
prostate cancer

Clinical features from OMIM®:

601518 (Updated 05-Mar-2021)

Drugs & Therapeutics for Prostate Cancer, Hereditary, 1

Drugs for Prostate Cancer, Hereditary, 1 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ethanol Approved 64-17-5 702

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Facilitating Participation in a Prostate Cancer Family Risk Assessment Program Completed NCT02126319
2 Prostate Cancer: Family Care for Patients and Spouses Completed NCT00708968

Search NIH Clinical Center for Prostate Cancer, Hereditary, 1

Genetic Tests for Prostate Cancer, Hereditary, 1

Genetic tests related to Prostate Cancer, Hereditary, 1:

# Genetic test Affiliating Genes
1 Prostate Cancer, Hereditary, 1 29 RNASEL

Anatomical Context for Prostate Cancer, Hereditary, 1

MalaCards organs/tissues related to Prostate Cancer, Hereditary, 1:

40
Prostate, Thyroid, Breast, Brain, Retina, Lung

Publications for Prostate Cancer, Hereditary, 1

Articles related to Prostate Cancer, Hereditary, 1:

(show top 50) (show all 110)
# Title Authors PMID Year
1
Germline mutations in the ribonuclease L gene in families showing linkage with HPC1. 61 54 57 6
11799394 2002
2
PCAP is the major known prostate cancer predisposing locus in families from south and west Europe. 61 57
11313747 2001
3
Combined analysis of hereditary prostate cancer linkage to 1q24-25: results from 772 hereditary prostate cancer families from the International Consortium for Prostate Cancer Genetics. 57 61
10712209 2000
4
Prostate cancer susceptibility locus HPC1 in Utah high-risk pedigrees. 61 57
10556291 1999
5
In Swedish families with hereditary prostate cancer, linkage to the HPC1 locus on chromosome 1q24-25 is restricted to families with early-onset prostate cancer. 61 57
10364525 1999
6
Linkage analysis of chromosome 1q markers in 136 prostate cancer families. The Cancer Research Campaign/British Prostate Group U.K. Familial Prostate Cancer Study Collaborators. 61 57
9497242 1998
7
Linkage analysis of 49 high-risk families does not support a common familial prostate cancer-susceptibility gene at 1q24-25. 61 57
9311739 1997
8
Prostate cancer susceptibility locus on chromosome 1q: a confirmatory study. 57 61
9214675 1997
9
Major susceptibility locus for prostate cancer on chromosome 1 suggested by a genome-wide search. 57
8910276 1996
10
Genetic alterations in untreated metastases and androgen-independent prostate cancer detected by comparative genomic hybridization and allelotyping. 57
8674067 1996
11
[RNase L, a crucial mediator of innate immunity and other cell functions]. 54 61
18950583 2008
12
Mapping of the human RNASEL promoter and expression in cancer and normal cells. 61 54
16241858 2005
13
HPC1/RNASEL mediates apoptosis of prostate cancer cells treated with 2',5'-oligoadenylates, topoisomerase I inhibitors, and tumor necrosis factor-related apoptosis-inducing ligand. 54 61
15604285 2004
14
Effects of RNase L mutations associated with prostate cancer on apoptosis induced by 2',5'-oligoadenylates. 54 61
14583476 2003
15
Implications for RNase L in prostate cancer biology. 61 54
12590567 2003
16
Principal components for morphometric traits in Campolina horses. 61
33137219 2021
17
Culture of Mesenchymal Stem Cells in a Hydrogel Model of Vocal Fold Lamina Propria. 61
33184606 2019
18
Mouse acute leukemia develops independent of self-renewal and differentiation potentials in hematopoietic stem and progenitor cells. 61
30733302 2019
19
RNase L Suppresses Androgen Receptor Signaling, Cell Migration and Matrix Metalloproteinase Activity in Prostate Cancer Cells. 61
28257035 2017
20
Lung Cancer-Targeting Peptides with Multi-subtype Indication for Combinational Drug Delivery and Molecular Imaging. 61
28529640 2017
21
The Hsp72 and Hsp90α mRNA Responses to Hot Downhill Running Are Reduced Following a Prior Bout of Hot Downhill Running, and Occur Concurrently within Leukocytes and the Vastus Lateralis. 61
28747888 2017
22
Photo- and thermochromic and adsorption properties of porous coordination polymers based on bipyridinium carboxylate ligands. 61
26370743 2015
23
[Hereditary prostate cancer]. 61
24864115 2014
24
PAC1-expressing structures of neural retina alter their PAC1 isoform splicing during postnatal development. 61
24352804 2014
25
Genetic analysis of the principal genes related to prostate cancer: a review. 61
23141781 2013
26
Halobacterium piscisalsi Yachai et al. 2008 is a later heterotypic synonym of Halobacterium salinarum Elazari-Volcani 1957. 61
22058320 2012
27
Effects of hen production cycle and egg weight on egg quality and composition, hatchability, duckling quality, and first-week body weight in Pekin ducks. 61
22010253 2011
28
New insights into the role of RNase L in innate immunity. 61
21190483 2011
29
Contribution of HPC1 (RNASEL) and HPCX variants to prostate cancer in a founder population. 61
20564318 2010
30
Xenotropic murine leukemia virus-related virus establishes an efficient spreading infection and exhibits enhanced transcriptional activity in prostate carcinoma cells. 61
20015990 2010
31
Single and multivariate associations of MSR1, ELAC2, and RNASEL with prostate cancer in an ethnic diverse cohort of men. 61
20086112 2010
32
Advances in biomarkers for the early diagnosis of prostate cancer. 61
20109357 2010
33
[G138A polymorphism of the RNASEL gene and its association with the development of prostate cancer. Preliminary study]. 61
19961052 2009
34
A fragile site within the HPC1 region at 1q25.3 affecting RGS16, RGSL1, and RGSL2 in human breast carcinomas. 61
18521847 2008
35
Halobacterium piscisalsi sp. nov., from fermented fish (pla-ra) in Thailand. 61
18768619 2008
36
Analysis of the RNASEL/HPC1, and macrophage scavenger receptor 1 in Asian-Indian advanced prostate cancer. 61
18436282 2008
37
Pathological aggressiveness of prostatic carcinomas related to RNASEL R462Q allelic variants. 61
18289577 2008
38
A genome-wide association screen identifies regions on chromosomes 1q25 and 7p21 as risk loci for sporadic prostate cancer. 61
17876339 2008
39
A scientific journey through the 2-5A/RNase L system. 54
17681844 2007
40
Polycomb-group oncogenes EZH2, BMI1, and RING1 are overexpressed in prostate cancer with adverse pathologic and clinical features. 61
17134822 2007
41
Molecular biology in prostate cancer. 61
16648113 2006
42
Prevalent mutations in prostate cancer. 61
16267836 2006
43
Involvement of the RNAse L gene in prostate cancer. 61
16869093 2006
44
A transcriptional signaling pathway in the IFN system mediated by 2'-5'-oligoadenylate activation of RNase L. 61
16203993 2005
45
A transposon-based activation-tagging population in Arabidopsis thaliana (TAMARA) and its application in the identification of dominant developmental and metabolic mutations. 61
16087178 2005
46
Association of susceptibility alleles in ELAC2/HPC2, RNASEL/HPC1, and MSR1 with prostate cancer severity in European American and African American men. 61
15824169 2005
47
Loss of heterozygosity: an independent prognostic factor of colorectal cancer. 61
15682467 2005
48
A convenient and sensitive fluorescence resonance energy transfer assay for RNase L and 2',5' oligoadenylates. 54
16000857 2005
49
Genetic analysis of the RNASEL gene in hereditary, familial, and sporadic prostate cancer. 61
15534086 2004
50
Thyroid hormone regulation of prohormone convertase 1 (PC1): regional expression in rat brain and in vitro characterization of negative thyroid hormone response elements. 61
15291740 2004

Variations for Prostate Cancer, Hereditary, 1

ClinVar genetic disease variations for Prostate Cancer, Hereditary, 1:

6 (show top 50) (show all 770)
# Gene Name Type Significance ClinVarId dbSNP ID GRCh37 Pos GRCh38 Pos
1 PRNCR1 NR_109833.1(PRNCR1):n.11999A>G SNV association 979039 8:128104117-128104117 8:127091872-127091872
2 CASC19 SNV association 979041 8:128205878-128205878 8:127193633-127193633
3 CASC19 SNV association 979042 8:128208369-128208369 8:127196124-127196124
4 CASC21 Microsatellite association 979043 8:128285409-128285412 8:127273164-127273167
5 CASC21 Duplication association 979044 8:128337272-128337273 8:127325027-127325028
6 CASC8 SNV association 979045 8:128479976-128479976 8:127467731-127467731
7 RNASEL NM_021133.4(RNASEL):c.793G>T (p.Glu265Ter) SNV Pathogenic 13004 rs74315364 1:182555149-182555149 1:182586014-182586014
8 RNASEL NM_021133.4(RNASEL):c.3G>A (p.Met1Ile) SNV Pathogenic 13005 rs74315365 1:182555939-182555939 1:182586804-182586804
9 HOXB13 NM_006361.5(HOXB13):c.101C>A (p.Thr34Asn) SNV Uncertain significance 690487 rs1597935112 17:46805855-46805855 17:48728493-48728493
10 HOXB13 NM_006361.5(HOXB13):c.105C>A (p.Ser35Arg) SNV Uncertain significance 690488 rs1175466694 17:46805851-46805851 17:48728489-48728489
11 HOXB13 NM_006361.5(HOXB13):c.109C>A (p.Pro37Thr) SNV Uncertain significance 690489 rs1597935093 17:46805847-46805847 17:48728485-48728485
12 HOXB13 NM_006361.5(HOXB13):c.116C>G (p.Ala39Gly) SNV Uncertain significance 690490 rs773491778 17:46805840-46805840 17:48728478-48728478
13 HOXB13 NM_006361.5(HOXB13):c.124C>G (p.Leu42Val) SNV Uncertain significance 690491 rs1597935049 17:46805832-46805832 17:48728470-48728470
14 HOXB13 NM_006361.5(HOXB13):c.132T>C (p.Pro44=) SNV Uncertain significance 690492 rs1597935042 17:46805824-46805824 17:48728462-48728462
15 HOXB13 NM_006361.5(HOXB13):c.134C>G (p.Ala45Gly) SNV Uncertain significance 690493 rs1597935038 17:46805822-46805822 17:48728460-48728460
16 HOXB13 NM_006361.5(HOXB13):c.141C>A (p.Asn47Lys) SNV Uncertain significance 690494 rs774872614 17:46805815-46805815 17:48728453-48728453
17 HOXB13 NM_006361.5(HOXB13):c.157C>T (p.Leu53=) SNV Uncertain significance 690495 rs1597934989 17:46805799-46805799 17:48728437-48728437
18 HOXB13 NM_006361.5(HOXB13):c.160C>A (p.Pro54Thr) SNV Uncertain significance 690496 rs769074510 17:46805796-46805796 17:48728434-48728434
19 HOXB13 NM_006361.5(HOXB13):c.175C>G (p.Pro59Ala) SNV Uncertain significance 690497 rs1597934900 17:46805781-46805781 17:48728419-48728419
20 HOXB13 NM_006361.5(HOXB13):c.189C>A (p.Cys63Ter) SNV Uncertain significance 690498 rs1597934839 17:46805767-46805767 17:48728405-48728405
21 HOXB13 NM_006361.5(HOXB13):c.210C>A (p.Pro70=) SNV Uncertain significance 690499 rs768670673 17:46805746-46805746 17:48728384-48728384
22 HOXB13 NM_006361.5(HOXB13):c.212A>G (p.Gln71Arg) SNV Uncertain significance 690500 rs1597934778 17:46805744-46805744 17:48728382-48728382
23 HOXB13 NM_006361.5(HOXB13):c.215G>A (p.Gly72Glu) SNV Uncertain significance 690501 rs774579054 17:46805741-46805741 17:48728379-48728379
24 HOXB13 NM_006361.5(HOXB13):c.230_231del (p.Pro77fs) Deletion Uncertain significance 690502 rs1597934719 17:46805725-46805726 17:48728363-48728364
25 HOXB13 NM_006361.5(HOXB13):c.-23C>G SNV Uncertain significance 690503 rs1597935521 17:46805978-46805978 17:48728616-48728616
26 HOXB13 NM_006361.5(HOXB13):c.244T>G (p.Tyr82Asp) SNV Uncertain significance 690504 rs1597934684 17:46805712-46805712 17:48728350-48728350
27 HOXB13 NM_006361.5(HOXB13):c.259T>G (p.Tyr87Asp) SNV Uncertain significance 690505 rs1597934636 17:46805697-46805697 17:48728335-48728335
28 HOXB13 NM_006361.5(HOXB13):c.267C>T (p.Ser89=) SNV Uncertain significance 690506 rs1597934607 17:46805689-46805689 17:48728327-48728327
29 HOXB13 NM_006361.5(HOXB13):c.-28del Deletion Uncertain significance 690507 rs1597935537 17:46805983-46805983 17:48728621-48728621
30 HOXB13 NM_006361.5(HOXB13):c.39G>T (p.Lys13Asn) SNV Uncertain significance 690508 rs1555558715 17:46805917-46805917 17:48728555-48728555
31 HOXB13 NM_006361.5(HOXB13):c.-44del Deletion Uncertain significance 690509 rs1597935602 17:46805999-46805999 17:48728637-48728637
32 HOXB13 NM_006361.5(HOXB13):c.48A>T (p.Glu16Asp) SNV Uncertain significance 690510 rs1597935280 17:46805908-46805908 17:48728546-48728546
33 HOXB13 NM_006361.5(HOXB13):c.505T>A (p.Tyr169Asn) SNV Uncertain significance 690511 rs1597933974 17:46805451-46805451 17:48728089-48728089
34 HOXB13 NM_006361.5(HOXB13):c.54del (p.Leu18fs) Deletion Uncertain significance 690512 rs1597935268 17:46805902-46805902 17:48728540-48728540
35 HOXB13 NM_006361.5(HOXB13):c.-55C>G SNV Uncertain significance 690513 rs1597935647 17:46806010-46806010 17:48728648-48728648
36 HOXB13 NM_006361.5(HOXB13):c.574G>C (p.Gly192Arg) SNV Uncertain significance 690514 rs1274753809 17:46805382-46805382 17:48728020-48728020
37 HOXB13 NM_006361.5(HOXB13):c.578C>G (p.Pro193Arg) SNV Uncertain significance 690515 rs1597933762 17:46805378-46805378 17:48728016-48728016
38 HOXB13 NM_006361.5(HOXB13):c.595T>C (p.Phe199Leu) SNV Uncertain significance 690516 rs1597933703 17:46805361-46805361 17:48727999-48727999
39 HOXB13 NM_006361.5(HOXB13):c.79C>A (p.Leu27Met) SNV Uncertain significance 690517 rs1597935186 17:46805877-46805877 17:48728515-48728515
40 HOXB13 NM_006361.5(HOXB13):c.82del (p.Val28fs) Deletion Uncertain significance 690518 rs1597935175 17:46805874-46805874 17:48728512-48728512
41 HOXB13 NM_006361.5(HOXB13):c.84del (p.Ala29fs) Deletion Uncertain significance 690519 rs1597935169 17:46805872-46805872 17:48728510-48728510
42 HOXB13 NM_006361.5(HOXB13):c.10_11insC (p.Gly4fs) Insertion Uncertain significance 690520 rs1597935406 17:46805945-46805946 17:48728583-48728584
43 HOXB13 NM_006361.5(HOXB13):c.100A>T (p.Thr34Ser) SNV Uncertain significance 690521 rs1418039435 17:46805856-46805856 17:48728494-48728494
44 HOXB13 NM_006361.5(HOXB13):c.101C>T (p.Thr34Ile) SNV Uncertain significance 690522 rs1597935112 17:46805855-46805855 17:48728493-48728493
45 HOXB13 NM_006361.5(HOXB13):c.102C>A (p.Thr34=) SNV Uncertain significance 690523 rs1597935105 17:46805854-46805854 17:48728492-48728492
46 HOXB13 NM_006361.5(HOXB13):c.102del (p.Ser35fs) Deletion Uncertain significance 690524 rs1597935108 17:46805854-46805854 17:48728492-48728492
47 HOXB13 NM_006361.5(HOXB13):c.106del (p.His36fs) Deletion Uncertain significance 690525 rs1597935100 17:46805850-46805850 17:48728488-48728488
48 HOXB13 NM_006361.5(HOXB13):c.107A>C (p.His36Pro) SNV Uncertain significance 690526 rs1597935095 17:46805849-46805849 17:48728487-48728487
49 HOXB13 NM_006361.5(HOXB13):c.109_110insA (p.Pro37fs) Insertion Uncertain significance 690527 rs1597935091 17:46805846-46805847 17:48728484-48728485
50 HOXB13 NM_006361.5(HOXB13):c.11dup (p.Asn5fs) Duplication Uncertain significance 690528 rs1597935405 17:46805944-46805945 17:48728582-48728583

Cosmic variations for Prostate Cancer, Hereditary, 1:

9 (show top 50) (show all 7592)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM87273255 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.8849G>A p.R2950H 16:72793833-72793833 18
2 COSM87278310 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.5650G>T p.E1884* 16:72797032-72797032 18
3 COSM102023521 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.598C>T p.R200* 16:72889839-72889839 18
4 COSM102020948 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.791C>A p.S264* 16:72812035-72812035 18
5 COSM102027229 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.2908G>T p.E970* 16:72797032-72797032 18
6 COSM149310968 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.5893C>T p.Q1965* 16:72796789-72796789 18
7 COSM87289963 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.2728G>A p.E910K 16:72950957-72950957 18
8 COSM87277276 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.2986A>T p.K996* 16:72950699-72950699 18
9 COSM102022171 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.6107G>A p.R2036H 16:72793833-72793833 18
10 COSM102025889 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.244A>T p.K82* 16:72950699-72950699 18
11 COSM149331699 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.5114C>G p.S1705* 16:72797568-72797568 18
12 COSM87287233 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.4819C>T p.Q1607* 16:72797863-72797863 18
13 COSM87296500 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.5114C>G p.S1705* 16:72797568-72797568 18
14 COSM149269669 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.3340C>T p.R1114* 16:72889839-72889839 18
15 COSM87271970 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.3533C>A p.S1178* 16:72812035-72812035 18
16 COSM149281678 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.5650G>T p.E1884* 16:72797032-72797032 18
17 COSM149265910 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.8849G>A p.R2950H 16:72793833-72793833 18
18 COSM87274612 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.3340C>T p.R1114* 16:72889839-72889839 18
19 COSM102031608 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.-23-8776C>G p.? 16:72959741-72959741 18
20 COSM149307401 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.4819C>T p.Q1607* 16:72797863-72797863 18
21 COSM87288892 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.5893C>T p.Q1965* 16:72796789-72796789 18
22 COSM149287761 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.6445C>T p.R2149C 16:72796237-72796237 18
23 COSM102037736 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.2077C>T p.Q693* 16:72797863-72797863 18
24 COSM149262752 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.3533C>A p.S1178* 16:72812035-72812035 18
25 COSM87281944 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.405C>G p.Y135* 16:72959741-72959741 18
26 COSM102047721 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.2372C>G p.S791* 16:72797568-72797568 18
27 COSM102029776 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.3703C>T p.R1235C 16:72796237-72796237 18
28 COSM87280241 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.6445C>T p.R2149C 16:72796237-72796237 18
29 COSM149314230 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.2728G>A p.E910K 16:72950957-72950957 18
30 COSM149278210 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.2986A>T p.K996* 16:72950699-72950699 18
31 COSM102039151 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.3151C>T p.Q1051* 16:72796789-72796789 18
32 COSM102040223 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.-15G>A p.? 16:72950957-72950957 18
33 COSM149292073 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.405C>G p.Y135* 16:72959741-72959741 18
34 COSM89894202 YES1 prostate,NS,carcinoma,adenocarcinoma c.119C>G p.S40* 18:756709-756709 18
35 COSM136834926 YES1 prostate,NS,carcinoma,adenocarcinoma c.590-1G>T p.? 18:745858-745858 18
36 COSM152021810 YES1 prostate,NS,carcinoma,adenocarcinoma c.575-1G>T p.? 18:745858-745858 18
37 COSM152022004 YES1 prostate,NS,carcinoma,adenocarcinoma c.119C>G p.S40* 18:756709-756709 18
38 COSM136836036 YES1 prostate,NS,carcinoma,adenocarcinoma c.134C>G p.S45* 18:756709-756709 18
39 COSM89892790 YES1 prostate,NS,carcinoma,adenocarcinoma c.575-1G>T p.? 18:745858-745858 18
40 COSM104882949 XPO1 prostate,NS,carcinoma,adenocarcinoma c.1259T>C p.M420T 2:61493040-61493040 18
41 COSM104239299 XPO1 prostate,NS,carcinoma,adenocarcinoma c.1384G>T p.V462F 2:61492915-61492915 18
42 COSM101975701 XPO1 prostate,NS,carcinoma,adenocarcinoma c.1711G>A p.E571K 2:61492337-61492337 18
43 COSM101977073 XPO1 prostate,NS,carcinoma,adenocarcinoma c.1259T>C p.M420T 2:61493040-61493040 18
44 COSM101976154 XPO1 prostate,NS,carcinoma,adenocarcinoma c.2468T>G p.F823C 2:61485808-61485808 18
45 COSM104881227 XPO1 prostate,NS,carcinoma,adenocarcinoma c.1711G>A p.E571K 2:61492337-61492337 18
46 COSM104238027 XPO1 prostate,NS,carcinoma,adenocarcinoma c.3101T>G p.F1034C 2:61478935-61478935 18
47 COSM104236414 XPO1 prostate,NS,carcinoma,adenocarcinoma c.1259T>C p.M420T 2:61493040-61493040 18
48 COSM101979599 XPO1 prostate,NS,carcinoma,adenocarcinoma c.1384G>T p.V462F 2:61492915-61492915 18
49 COSM101981883 XPO1 prostate,NS,carcinoma,adenocarcinoma c.1098T>A p.F366L 2:61494041-61494041 18
50 COSM104888806 XPO1 prostate,NS,carcinoma,adenocarcinoma c.1098T>A p.F366L 2:61494041-61494041 18

Expression for Prostate Cancer, Hereditary, 1

Search GEO for disease gene expression data for Prostate Cancer, Hereditary, 1.

Pathways for Prostate Cancer, Hereditary, 1

GO Terms for Prostate Cancer, Hereditary, 1

Sources for Prostate Cancer, Hereditary, 1

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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