MCID: PRS031
MIFTS: 27

Prostate Carcinoma in Situ

Categories: Cancer diseases, Genetic diseases, Rare diseases, Reproductive diseases

Aliases & Classifications for Prostate Carcinoma in Situ

MalaCards integrated aliases for Prostate Carcinoma in Situ:

Name: Prostate Carcinoma in Situ 12 15
Carcinoma in Situ of Prostate 12 74
Grade Iii Pin 12
Pin Iii 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8634
ICD9CM 36 233.4
NCIt 51 C3642
SNOMED-CT 69 92691004
ICD10 34 D07.5
UMLS 74 C0154088

Summaries for Prostate Carcinoma in Situ

Disease Ontology : 12 An in situ carcinoma that is located in the prostate.

MalaCards based summary : Prostate Carcinoma in Situ, also known as carcinoma in situ of prostate, is related to prostate cancer and in situ carcinoma. An important gene associated with Prostate Carcinoma in Situ is LPP (LIM Domain Containing Preferred Translocation Partner In Lipoma), and among its related pathways/superpathways are Carbon metabolism and Citrate cycle (TCA cycle). Affiliated tissues include the prostate and prostate, and related phenotypes are Decreased DCP1a protein expression and assembly in processing bodies after arsenite stimulation and adipose tissue

Related Diseases for Prostate Carcinoma in Situ

Symptoms & Phenotypes for Prostate Carcinoma in Situ

GenomeRNAi Phenotypes related to Prostate Carcinoma in Situ according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased DCP1a protein expression and assembly in processing bodies after arsenite stimulation GR00203-A 8.62 ALDOA ALDOB

MGI Mouse Phenotypes related to Prostate Carcinoma in Situ:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 adipose tissue MP:0005375 8.62 SLURP1 TMPRSS15

Drugs & Therapeutics for Prostate Carcinoma in Situ

Search Clinical Trials , NIH Clinical Center for Prostate Carcinoma in Situ

Genetic Tests for Prostate Carcinoma in Situ

Anatomical Context for Prostate Carcinoma in Situ

The Foundational Model of Anatomy Ontology organs/tissues related to Prostate Carcinoma in Situ:

20
The Prostate

MalaCards organs/tissues related to Prostate Carcinoma in Situ:

42
Prostate

Publications for Prostate Carcinoma in Situ

Articles related to Prostate Carcinoma in Situ:

# Title Authors Year
1
Induction of prostate carcinoma in situ at high incidence in F344 rats by a combination of 3,2'-dimethyl-4-aminobiphenyl and ethinyl estradiol. ( 3779655 )
1986
2
Differential diagnosis in uropathology, carcinoma in situ of prostate gland. ( 1114536 )
1975

Variations for Prostate Carcinoma in Situ

Expression for Prostate Carcinoma in Situ

Search GEO for disease gene expression data for Prostate Carcinoma in Situ.

Pathways for Prostate Carcinoma in Situ

GO Terms for Prostate Carcinoma in Situ

Biological processes related to Prostate Carcinoma in Situ according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 gluconeogenesis GO:0006094 9.32 ALDOA ALDOB
2 glycolytic process GO:0006096 9.26 ALDOA ALDOB
3 canonical glycolysis GO:0061621 9.16 ALDOA ALDOB
4 fructose metabolic process GO:0006000 8.96 ALDOA ALDOB
5 fructose 1,6-bisphosphate metabolic process GO:0030388 8.62 ALDOA ALDOB

Molecular functions related to Prostate Carcinoma in Situ according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lyase activity GO:0016829 9.26 ALDOA ALDOB
2 cytoskeletal protein binding GO:0008092 9.16 ALDOA ALDOB
3 fructose binding GO:0070061 8.96 ALDOA ALDOB
4 fructose-bisphosphate aldolase activity GO:0004332 8.62 ALDOA ALDOB

Sources for Prostate Carcinoma in Situ

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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