MCID: PRS031
MIFTS: 21

Prostate Carcinoma in Situ

Categories: Cancer diseases, Genetic diseases, Rare diseases, Reproductive diseases

Aliases & Classifications for Prostate Carcinoma in Situ

MalaCards integrated aliases for Prostate Carcinoma in Situ:

Name: Prostate Carcinoma in Situ 12 15
Carcinoma in Situ of Prostate 12 70
Grade Iii Pin 12
Pin Iii 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8634
ICD9CM 34 233.4
SNOMED-CT 67 92691004
ICD10 32 D07.5
UMLS 70 C0154088

Summaries for Prostate Carcinoma in Situ

Disease Ontology : 12 An in situ carcinoma that is located in the prostate.

MalaCards based summary : Prostate Carcinoma in Situ, also known as carcinoma in situ of prostate, is related to in situ carcinoma and polyposis syndrome, hereditary mixed, 1. An important gene associated with Prostate Carcinoma in Situ is LPP (LIM Domain Containing Preferred Translocation Partner In Lipoma). Affiliated tissues include prostate, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Prostate Carcinoma in Situ

Symptoms & Phenotypes for Prostate Carcinoma in Situ

GenomeRNAi Phenotypes related to Prostate Carcinoma in Situ according to GeneCards Suite gene sharing:

26 (show all 23)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-10 9.7 BUB1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-101 9.7 DYNLL1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-104 9.7 DYNLL1
4 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.7 BUB1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-106 9.7 BUB1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-107 9.7 DYNLL1
7 Increased shRNA abundance (Z-score > 2) GR00366-A-122 9.7 DYNLL1
8 Increased shRNA abundance (Z-score > 2) GR00366-A-136 9.7 DYNLL1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-153 9.7 DYNLL1
10 Increased shRNA abundance (Z-score > 2) GR00366-A-168 9.7 FBXW2
11 Increased shRNA abundance (Z-score > 2) GR00366-A-176 9.7 BUB1
12 Increased shRNA abundance (Z-score > 2) GR00366-A-189 9.7 FBXW2
13 Increased shRNA abundance (Z-score > 2) GR00366-A-195 9.7 DYNLL1
14 Increased shRNA abundance (Z-score > 2) GR00366-A-214 9.7 FBXW2
15 Increased shRNA abundance (Z-score > 2) GR00366-A-216 9.7 DYNLL1
16 Increased shRNA abundance (Z-score > 2) GR00366-A-43 9.7 DYNLL1
17 Increased shRNA abundance (Z-score > 2) GR00366-A-5 9.7 BUB1
18 Increased shRNA abundance (Z-score > 2) GR00366-A-59 9.7 FBXW2
19 Increased shRNA abundance (Z-score > 2) GR00366-A-73 9.7 FBXW2
20 Increased shRNA abundance (Z-score > 2) GR00366-A-78 9.7 BUB1 DYNLL1
21 Increased shRNA abundance (Z-score > 2) GR00366-A-8 9.7 BUB1
22 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.7 BUB1
23 Increased shRNA abundance (Z-score > 2) GR00366-A-87 9.7 BUB1

MGI Mouse Phenotypes related to Prostate Carcinoma in Situ:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.17 BUB1 DYNLL1 GREM1 LPP NKX3-1 PNPT1

Drugs & Therapeutics for Prostate Carcinoma in Situ

Search Clinical Trials , NIH Clinical Center for Prostate Carcinoma in Situ

Genetic Tests for Prostate Carcinoma in Situ

Anatomical Context for Prostate Carcinoma in Situ

The Foundational Model of Anatomy Ontology organs/tissues related to Prostate Carcinoma in Situ:

19
Prostate

MalaCards organs/tissues related to Prostate Carcinoma in Situ:

40
Prostate

Publications for Prostate Carcinoma in Situ

Articles related to Prostate Carcinoma in Situ:

# Title Authors PMID Year
1
Prospective evaluation of the clinical usefulness of reflex fluorescence in situ hybridization assay in patients with atypical cytology for the detection of urothelial carcinoma of the bladder. 61
18423745 2008
2
Induction of prostate carcinoma in situ at high incidence in F344 rats by a combination of 3,2'-dimethyl-4-aminobiphenyl and ethinyl estradiol. 61
3779655 1986
3
Differential diagnosis in uropathology, carcinoma in situ of prostate gland. 61
1114536 1975

Variations for Prostate Carcinoma in Situ

Expression for Prostate Carcinoma in Situ

Search GEO for disease gene expression data for Prostate Carcinoma in Situ.

Pathways for Prostate Carcinoma in Situ

GO Terms for Prostate Carcinoma in Situ

Cellular components related to Prostate Carcinoma in Situ according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytosol GO:0005829 9.23 PNPT1 NKX3-1 LPP FBXW2 DYNLL1 DNAJC5

Biological processes related to Prostate Carcinoma in Situ according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitotic cell cycle arrest GO:0071850 8.62 PNPT1 NKX3-1

Sources for Prostate Carcinoma in Situ

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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