MCID: PRS032
MIFTS: 30

Prostate Leiomyosarcoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Prostate Leiomyosarcoma

MalaCards integrated aliases for Prostate Leiomyosarcoma:

Name: Prostate Leiomyosarcoma 12 15 73
Leiomyosarcoma of the Prostate 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5282
NCIt 50 C5526
UMLS 73 C1335511

Summaries for Prostate Leiomyosarcoma

Disease Ontology : 12 A prostate sarcoma that is located in the prostate.

MalaCards based summary : Prostate Leiomyosarcoma, also known as leiomyosarcoma of the prostate, is related to leiomyosarcoma and warthin tumor. An important gene associated with Prostate Leiomyosarcoma is CYP27A1 (Cytochrome P450 Family 27 Subfamily A Member 1), and among its related pathways/superpathways are NF-kappaB Signaling and Cushing syndrome. Affiliated tissues include prostate, lung and liver, and related phenotypes are hematopoietic system and homeostasis/metabolism

Related Diseases for Prostate Leiomyosarcoma

Diseases related to Prostate Leiomyosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 36)
# Related Disease Score Top Affiliating Genes
1 leiomyosarcoma 10.2
2 warthin tumor 10.1 CD44 KIT
3 gastric cardia carcinoma 10.1 CD44 KIT
4 gallbladder leiomyoma 10.1 CD34 KIT
5 lung leiomyosarcoma 10.1 CD34 KIT
6 liver leiomyoma 10.1 CD34 KIT
7 deep leiomyoma 10.1 CD34 KIT
8 extracutaneous mastocytoma 10.1 CD34 KIT
9 small intestine leiomyosarcoma 10.1 CD34 KIT
10 small intestinal sarcoma 10.1 CD34 KIT
11 gallbladder sarcoma 10.1 CD34 KIT
12 plexiform schwannoma 10.1 CD34 KIT
13 conventional fibrosarcoma 10.1 CD34 KIT
14 peritoneal benign neoplasm 10.1 CD34 KIT
15 diffuse peritoneal leiomyomatosis 10.1 CD34 KIT
16 breast angiosarcoma 10.1 CD34 KIT
17 senile angioma 10.1 CD34 KIT
18 angiomyoma 10.1 CD34 KIT
19 spindle cell liposarcoma 10.1 CD34 KIT
20 mesenchymal cell neoplasm 10.1 CD34 KIT
21 cardiovascular organ benign neoplasm 10.1 CD34 KIT
22 congenital epulis 10.1 CD34 CD44
23 benign perivascular tumor 10.0 CD34 KIT
24 nervous system benign neoplasm 10.0 CD34 KIT
25 muscle cancer 10.0 CD34 KIT
26 vascular cancer 10.0 CD34 KIT
27 autosomal dominant non-syndromic intellectual disability 2 10.0 HPGDS KIT
28 connective tissue cancer 10.0 CD34 KIT
29 gastrointestinal system cancer 10.0 CD34 CD44 KIT
30 gastrointestinal stromal tumor 10.0 CD34 CD44 KIT
31 neurofibroma 10.0 CD34 KIT
32 myeloma, multiple 9.9 CD34 CD44 KIT
33 leukocyte disease 9.9 CD34 KIT
34 adenocarcinoma 9.9
35 dermatofibrosarcoma protuberans 9.8 CD34 KIT
36 large intestine cancer 9.7 CD34 CD44 HPGDS

Graphical network of the top 20 diseases related to Prostate Leiomyosarcoma:



Diseases related to Prostate Leiomyosarcoma

Symptoms & Phenotypes for Prostate Leiomyosarcoma

MGI Mouse Phenotypes related to Prostate Leiomyosarcoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.8 CD34 CD44 CYP27A1 GPSM3 KIT PLCB2
2 homeostasis/metabolism MP:0005376 9.8 CD34 CD44 CYP27A1 HPGDS KIT PLCB2
3 integument MP:0010771 9.55 CD34 CD44 HPGDS KIT PLCB2
4 neoplasm MP:0002006 9.26 CD34 CD44 HPGDS KIT
5 nervous system MP:0003631 9.17 CD44 CYP27A1 GPSM3 HPGDS KIT PLCB2

Drugs & Therapeutics for Prostate Leiomyosarcoma

Search Clinical Trials , NIH Clinical Center for Prostate Leiomyosarcoma

Genetic Tests for Prostate Leiomyosarcoma

Anatomical Context for Prostate Leiomyosarcoma

MalaCards organs/tissues related to Prostate Leiomyosarcoma:

41
Prostate, Lung, Liver, Small Intestine

The Foundational Model of Anatomy Ontology organs/tissues related to Prostate Leiomyosarcoma:

19
The Prostate

Publications for Prostate Leiomyosarcoma

Articles related to Prostate Leiomyosarcoma:

(show all 20)
# Title Authors Year
1
Long term follow-up of surgery management of prostate leiomyosarcoma metastasized to the rib: A case report and literature review. ( 27330784 )
2016
2
Leiomyosarcoma of the prostate-an unexpected histopathological outcome. ( 27284101 )
2016
3
A Review of the Literature on Primary Leiomyosarcoma of the Prostate Gland. ( 26640482 )
2015
4
Radiation-induced leiomyosarcoma of the prostate after brachytherapy for prostatic adenocarcinoma. ( 25232328 )
2014
5
Leiomyosarcoma of the prostate: case report and review of 54 previously published cases. ( 19043598 )
2008
6
Leiomyosarcoma of the prostate. ( 17574619 )
2007
7
Leiomyosarcoma of the prostate: a study of two cases. ( 11233325 )
2001
8
Leiomyosarcoma of the prostate. A case report. ( 8034429 )
1994
9
Cytogenetic findings in a primary leiomyosarcoma of the prostate. ( 3708549 )
1986
10
Leiomyosarcoma of the prostate. ( 2408894 )
1985
11
Leiomyosarcoma of the prostate in adults. ( 4083781 )
1985
12
Leiomyosarcoma of the prostate apparently cured by surgery and radical irradiation: report of a case. ( 7153095 )
1982
13
Leiomyosarcoma of the prostate: a case report. ( 498618 )
1979
14
Leiomyosarcoma of the prostate: a case report. ( 604070 )
1977
15
Leiomyosarcoma of the prostate. ( 1191929 )
1975
16
Leiomyosarcoma of the prostate. ( 4575149 )
1973
17
Translumbar amputation for advanced leiomyosarcoma of the prostate. ( 6016198 )
1967
18
Leiomyosarcoma of the prostate: case report and review of the literature. ( 13823325 )
1960
19
Leiomyosarcoma of the prostate: case report. ( 13197626 )
1954
20
Leiomyosarcoma of the prostate: a case report. ( 15443209 )
1950

Variations for Prostate Leiomyosarcoma

Expression for Prostate Leiomyosarcoma

Search GEO for disease gene expression data for Prostate Leiomyosarcoma.

Pathways for Prostate Leiomyosarcoma

Pathways related to Prostate Leiomyosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 12.06 CD34 CD44 KIT
2
Show member pathways
11.84 KIT PLCB2 RASD1
3 11.4 CD34 CD44 KIT
4 11.27 CD34 KIT
5 11.12 CD34 CD44 KIT
6 11.05 CD34 KIT
7 10.7 CD34 CD44 KIT

GO Terms for Prostate Leiomyosarcoma

Biological processes related to Prostate Leiomyosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 9.02 CD34 HPGDS KIT PLCB2 RASD1
2 hemopoiesis GO:0030097 8.96 CD34 KIT

Sources for Prostate Leiomyosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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