MCID: PRS032
MIFTS: 26

Prostate Leiomyosarcoma

Categories: Cancer diseases, Muscle diseases, Reproductive diseases

Aliases & Classifications for Prostate Leiomyosarcoma

MalaCards integrated aliases for Prostate Leiomyosarcoma:

Name: Prostate Leiomyosarcoma 12 15 73
Leiomyosarcoma of the Prostate 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5282
NCIt 50 C5526
UMLS 73 C1335511

Summaries for Prostate Leiomyosarcoma

Disease Ontology : 12 A prostate sarcoma that is located in the prostate.

MalaCards based summary : Prostate Leiomyosarcoma, also known as leiomyosarcoma of the prostate, is related to warthin tumor and gallbladder leiomyoma. An important gene associated with Prostate Leiomyosarcoma is CYP27A1 (Cytochrome P450 Family 27 Subfamily A Member 1), and among its related pathways/superpathways are NF-kappaB Signaling and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include the prostate and prostate, and related phenotypes are hematopoietic system and homeostasis/metabolism

Related Diseases for Prostate Leiomyosarcoma

Graphical network of the top 20 diseases related to Prostate Leiomyosarcoma:



Diseases related to Prostate Leiomyosarcoma

Symptoms & Phenotypes for Prostate Leiomyosarcoma

MGI Mouse Phenotypes related to Prostate Leiomyosarcoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.8 CD34 CD44 CYP27A1 GPSM3 KIT PLCB2
2 homeostasis/metabolism MP:0005376 9.8 CD34 CD44 CYP27A1 HPGDS KIT PLCB2
3 integument MP:0010771 9.55 CD34 CD44 HPGDS KIT PLCB2
4 neoplasm MP:0002006 9.26 CD34 CD44 HPGDS KIT
5 nervous system MP:0003631 9.17 CD44 CYP27A1 GPSM3 HPGDS KIT PLCB2

Drugs & Therapeutics for Prostate Leiomyosarcoma

Search Clinical Trials , NIH Clinical Center for Prostate Leiomyosarcoma

Genetic Tests for Prostate Leiomyosarcoma

Anatomical Context for Prostate Leiomyosarcoma

The Foundational Model of Anatomy Ontology organs/tissues related to Prostate Leiomyosarcoma:

19
The Prostate

MalaCards organs/tissues related to Prostate Leiomyosarcoma:

41
Prostate

Publications for Prostate Leiomyosarcoma

Articles related to Prostate Leiomyosarcoma:

# Title Authors Year
1
Long term follow-up of surgery management of prostate leiomyosarcoma metastasized to the rib: A case report and literature review. ( 27330784 )
2016
2
Primary prostatic leiomyosarcoma with pulmonary metastases in a dog. ( 20194365 )
2010

Variations for Prostate Leiomyosarcoma

Expression for Prostate Leiomyosarcoma

Search GEO for disease gene expression data for Prostate Leiomyosarcoma.

Pathways for Prostate Leiomyosarcoma

Pathways related to Prostate Leiomyosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 12.01 CD34 CD44 KIT
2 11.4 CD34 CD44 KIT
3 11.24 CD34 KIT
4 11.12 CD34 CD44 KIT
5 10.98 CD34 KIT
6 10.7 CD34 CD44 KIT

GO Terms for Prostate Leiomyosarcoma

Biological processes related to Prostate Leiomyosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hemopoiesis GO:0030097 8.96 CD34 KIT
2 positive regulation of kinase activity GO:0033674 8.62 CD44 KIT

Sources for Prostate Leiomyosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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