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MCID: PRS017
MIFTS: 24

Prostate Neuroendocrine Neoplasm

Categories: Cancer diseases, Neuronal diseases, Reproductive diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Prostate Neuroendocrine Neoplasm

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MalaCards integrated aliases for Prostate Neuroendocrine Neoplasm:

Name: Prostate Neuroendocrine Neoplasm 12 15 70
Neuroendocrine Tumor of the Prostate 12

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases Neuronal diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:2992
NCIt 50 C5545
UMLS 70 C1335515
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Summaries for Prostate Neuroendocrine Neoplasm

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MalaCards based summary : Prostate Neuroendocrine Neoplasm, also known as neuroendocrine tumor of the prostate, is related to neuroendocrine tumor and eyelid benign neoplasm. An important gene associated with Prostate Neuroendocrine Neoplasm is REST (RE1 Silencing Transcription Factor), and among its related pathways/superpathways are Neuroscience and Adhesion. Affiliated tissues include prostate, and related phenotype is nervous system.

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Related Diseases for Prostate Neuroendocrine Neoplasm

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Diseases related to Prostate Neuroendocrine Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 347)
# Related Disease Score Top Affiliating Genes
1 neuroendocrine tumor 30.3 SYP NCAM1 KRT20 ENO2 CHGA
2 eyelid benign neoplasm 10.4 KRT20 CHGA
3 urethral villous adenoma 10.4 KRT7 KRT20
4 bladder benign neoplasm 10.4 KRT7 KRT20
5 nephrogenic adenoma of urinary bladder 10.4 KRT7 KRT20
6 atrophic vulva 10.4 KRT7 KRT20
7 urinary bladder villous adenoma 10.4 KRT7 KRT20
8 vulva adenocarcinoma 10.4 KRT7 KRT20
9 mucinous ovarian cystadenoma 10.4 KRT7 KRT20
10 primary hepatic neuroendocrine carcinoma 10.4 SYP CHGA
11 rectosigmoid junction neoplasm 10.3 KRT7 KRT20
12 transverse colon cancer 10.3 KRT7 KRT20
13 sigmoid neoplasm 10.3 KRT7 KRT20
14 eyelid carcinoma 10.3 KRT7 KRT20
15 acinar cell cystadenocarcinoma 10.3 SYP CHGA
16 ovary neuroendocrine neoplasm 10.3 SYP KRT7
17 vulvar eccrine porocarcinoma 10.3 SYP CHGA
18 jejunal cancer 10.3 KRT7 KRT20
19 colonic lymphangioma 10.3 KRT7 KRT20
20 gastrointestinal neuroendocrine benign tumor 10.3 SYP CHGA
21 mucinous adenofibroma 10.3 SYP KRT7
22 mixed ductal-endocrine carcinoma 10.3 SYP CHGA
23 intratubular embryonal carcinoma 10.3 KRT7 KRT20
24 malignant syringoma 10.3 KRT7 KRT20
25 papillary transitional carcinoma 10.3 KRT7 KRT20
26 anal canal adenocarcinoma 10.3 KRT7 KRT20
27 duodenal benign neoplasm 10.3 SYP CHGA
28 supine hypotensive syndrome 10.3 KRT7 KRT20
29 mucinous bronchioloalveolar adenocarcinoma 10.3 KRT7 KRT20
30 malignant melanocytic neoplasm of the peripheral nerve sheath 10.3 SYP ENO2
31 jejunal adenocarcinoma 10.3 KRT7 KRT20
32 breast papillary carcinoma 10.3 SYP CHGA
33 optic nerve astrocytoma 10.3 SYP ENO2
34 rectum neuroendocrine neoplasm 10.3 SYP KRT7
35 cerebral neuroblastoma 10.3 SYP ENO2
36 gastric diffuse adenocarcinoma 10.3 KRT7 KRT20
37 neuronal intestinal dysplasia, type b 10.3 SYP ENO2
38 gastric neuroendocrine neoplasm 10.3 SYP CHGA
39 eccrine sweat gland cancer 10.3 KRT7 KRT20
40 lung meningioma 10.3 SYP ENO2
41 sinonasal undifferentiated carcinoma 10.3 SYP ENO2
42 glandular cystitis 10.3 KRT7 KRT20
43 pancreatic mucinous cystadenoma 10.3 KRT7 KRT20
44 papillary tumor of the pineal region 10.3 SYP ENO2
45 papillary squamous carcinoma 10.3 SYP KRT7
46 vaginal glandular tumor 10.3 ENO2 CHGA
47 cloacogenic carcinoma 10.3 SYP ENO2
48 pineal region teratoma 10.3 SYP ENO2
49 intracranial primitive neuroectodermal tumor 10.3 SYP ENO2
50 linitis plastica 10.3 KRT7 KRT20

Graphical network of the top 20 diseases related to Prostate Neuroendocrine Neoplasm:



Diseases related to Prostate Neuroendocrine Neoplasm
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Symptoms & Phenotypes for Prostate Neuroendocrine Neoplasm

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MGI Mouse Phenotypes related to Prostate Neuroendocrine Neoplasm:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.32 AR AURKA CD44 CHGA ENO2 MYCN
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Drugs & Therapeutics for Prostate Neuroendocrine Neoplasm

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Search Clinical Trials , NIH Clinical Center for Prostate Neuroendocrine Neoplasm

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Genetic Tests for Prostate Neuroendocrine Neoplasm

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Anatomical Context for Prostate Neuroendocrine Neoplasm

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MalaCards organs/tissues related to Prostate Neuroendocrine Neoplasm:

40
Prostate
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Publications for Prostate Neuroendocrine Neoplasm

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Articles related to Prostate Neuroendocrine Neoplasm:

# Title Authors PMID Year
1
Frontiers in Genitourinary Pathology. 61
32101057 2020
2
[Giant neuroendocrine tumor of the prostate]. 61
19900394 2009
3
FDG PET-CT demonstration of metastatic neuroendocrine tumor of prostate. 61
18565231 2008
4
Pure primary neuroendocrine tumor of the prostate: a rare entity. 61
16859584 2006
5
Primary and pure neuroendocrine tumor of the prostate. 61
14734001 2004
6
[Neuroendocrine tumor of the prostate. A case report]. 61
11859580 2002
7
[Neuroendocrine tumors of the prostate]. 61
8256680 1993
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Variations for Prostate Neuroendocrine Neoplasm

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Expression for Prostate Neuroendocrine Neoplasm

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Search GEO for disease gene expression data for Prostate Neuroendocrine Neoplasm.
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Pathways for Prostate Neuroendocrine Neoplasm

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Pathways related to Prostate Neuroendocrine Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Neuroscience 4
12.2 SYP NCAM1 MYCN ENO2
2
Adhesion 4
11.7 NCAM1 KLK3 CD44
3
Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers 64
11.64 PTPRC NCAM1 CD44
4
Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers 64
11.48 PTPRC NCAM1 CD44
5
Innate Lymphoid Cell Differentiation Pathways 64
11.34 PTPRC NCAM1 CD44
6
Neural Stem Cell Differentiation Pathways and Lineage-specific Markers 64
11.23 SYP NCAM1 CD44
7
Coregulation of Androgen receptor activity 1
10.89 TMPRSS2 KLK3 AR
8
Regulation of Androgen receptor activity 1
10.5 TMPRSS2 KLK3 AR
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GO Terms for Prostate Neuroendocrine Neoplasm

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Biological processes related to Prostate Neuroendocrine Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of systemic arterial blood pressure GO:0003073 8.62 KLK3 AR
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Sources for Prostate Neuroendocrine Neoplasm

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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