MCID: PRS043
MIFTS: 28

Prostate Rhabdomyosarcoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Prostate Rhabdomyosarcoma

MalaCards integrated aliases for Prostate Rhabdomyosarcoma:

Name: Prostate Rhabdomyosarcoma 12 15 17 71
Rhabdomyosarcoma of the Prostate 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3252
NCIt 49 C5522
UMLS 71 C1335518

Summaries for Prostate Rhabdomyosarcoma

Disease Ontology : 12 A rhabdomyosarcoma and sarcoma of prostate that is located in the prostate.

MalaCards based summary : Prostate Rhabdomyosarcoma, also known as rhabdomyosarcoma of the prostate, is related to prostate sarcoma and prostate embryonal rhabdomyosarcoma. An important gene associated with Prostate Rhabdomyosarcoma is MIR1915HG (MIR1915 Host Gene), and among its related pathways/superpathways are Arginine and proline metabolism and Urea cycle and metabolism of amino groups. Affiliated tissues include prostate and colon, and related phenotypes are Decreased viability and Decreased viability

Related Diseases for Prostate Rhabdomyosarcoma

Diseases related to Prostate Rhabdomyosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 25)
# Related Disease Score Top Affiliating Genes
1 prostate sarcoma 29.0 TMEM168 MIR1915HG CKMT2 CKMT1A
2 prostate embryonal rhabdomyosarcoma 11.7
3 rhabdomyosarcoma 10.7
4 rhabdomyosarcoma 2 10.0
5 spindle cell sarcoma 10.0
6 sudden infant death syndrome 9.9
7 hydronephrosis 9.9
8 sarcoma 9.9
9 respiratory failure 9.9
10 botryoid rhabdomyosarcoma 9.9
11 spindle cell rhabdomyosarcoma 9.9
12 47,xyy 9.9
13 48,xyyy 9.9
14 embryonal sarcoma 9.9
15 rare tumor 9.9
16 neurogenic bladder 9.9
17 detrusor sphincter dyssynergia 9.9
18 cystitis 9.9
19 impotence 9.9
20 constipation 9.9
21 proctitis 9.9
22 embryonal rhabdomyosarcoma 9.9
23 soft tissue sarcoma 9.9
24 rare soft tissue tumor 9.9
25 dressler's syndrome 9.7 CKMT2 CKMT1A

Graphical network of the top 20 diseases related to Prostate Rhabdomyosarcoma:



Diseases related to Prostate Rhabdomyosarcoma

Symptoms & Phenotypes for Prostate Rhabdomyosarcoma

GenomeRNAi Phenotypes related to Prostate Rhabdomyosarcoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00221-A-2 9.5 CKB CKM CKMT2
2 Decreased viability GR00221-A-3 9.5 CKMT2
3 Decreased viability GR00402-S-2 9.5 CKB CKM CKMT2
4 Increased human cytomegalovirus (HCMV) strain AD169 replication GR00248-A 8.8 CKB CKM CKMT2

Drugs & Therapeutics for Prostate Rhabdomyosarcoma

Search Clinical Trials , NIH Clinical Center for Prostate Rhabdomyosarcoma

Genetic Tests for Prostate Rhabdomyosarcoma

Anatomical Context for Prostate Rhabdomyosarcoma

The Foundational Model of Anatomy Ontology organs/tissues related to Prostate Rhabdomyosarcoma:

19
Prostate

MalaCards organs/tissues related to Prostate Rhabdomyosarcoma:

40
Prostate, Colon

Publications for Prostate Rhabdomyosarcoma

Articles related to Prostate Rhabdomyosarcoma:

(show top 50) (show all 115)
# Title Authors PMID Year
1
Patterns of failure and toxicity profile following proton beam therapy for pediatric bladder and prostate rhabdomyosarcoma. 61
31397065 2019
2
Current treatment of pediatric bladder and prostate rhabdomyosarcoma (bladder preserving vs. radical cystectomy). 61
31188163 2019
3
Laparoscopic bladder-sparing approach in patients with prostatic rhabdomyosarcoma: a case series of two pediatric patients. 61
31328249 2019
4
A Case of Adult Metastatic Rhabdomyosarcoma of the Prostate Cured by Long-Term Chemotherapy with Local Radiation. 61
28427078 2019
5
Testicular transposition in children undergoing brachytherapy for bladder and/or prostate rhabdomyosarcoma. 61
29753523 2018
6
Appraisal of the role of radical prostatectomy for rhabdomyosarcoma in children: oncological and urological outcome. 61
29899760 2018
7
Current Treatment of Pediatric Bladder and Prostate Rhabdomyosarcoma. 61
29468476 2018
8
Pulsed-dose rate brachytherapy for pediatric bladder prostate rhabdomyosarcoma: Compliance and early clinical results. 61
28760484 2017
9
Brachytherapy Combined With Surgery for Conservative Treatment of Children With Bladder Neck and/or Prostate Rhabdomyosarcoma. 61
28463154 2017
10
Improvements in the Treatment of Patients Suffering from Bladder-Prostate Rhabdomyosarcoma: A Report from the CWS-2002P Trial. 61
27387676 2016
11
Conservative surgery with combined high dose rate brachytherapy for patients suffering from genitourinary and perianal rhabdomyosarcoma. 61
27793447 2016
12
Prognostic factors in children undergoing salvage surgery for bladder/prostate rhabdomyosarcoma. 61
27255731 2016
13
Spindle cell embryonal rhabdomyosarcoma of the prostate in an adult patient - case report and review of clinicopathological features. 61
27357857 2016
14
Quality of life and functional outcome of male patients with bladder-prostate rhabdomyosarcoma treated with conservative surgery and brachytherapy during childhood. 61
26895712 2016
15
Current standards of care in bladder and prostate rhabdomyosarcoma. 61
26776454 2016
16
Pediatric bladder/prostate rhabdomyosarcoma: Eight cases from a single center. 61
28266189 2016
17
Contrast-enhanced ultrasound aids in the detection of prostate rhabdomyosarcoma: A case report and literature review. 61
26622705 2015
18
A review on surgical techniques and organ sparing procedures in bladder/prostate rhabdomyosarcoma. 61
25486411 2014
19
Prostate sarcoma: report of 2 cases and bibliographic review. 61
25306988 2014
20
Oncologic outcome and urinary function after radical cystectomy for rhabdomyosarcoma in children: role of the orthotopic ileal neobladder based on 15-year experience at a single center. 61
24384158 2014
21
Assessment of volume segmentation in radiotherapy of adolescents; a treatment planning study by the Swedish Workgroup for Paediatric Radiotherapy. 61
23577745 2014
22
A case of primary spindle cell variant of embryonal rhabdomyosarcoma of the prostate. 61
25197394 2014
23
Optimal surgical treatment and urological outcomes in boys with pelvic and urogenital rhabdomyosarcomas and soft tissue sarcomas. 61
23989524 2013
24
Spindle cell rhabdomyosarcoma of the prostate. 61
23320845 2013
25
The surgical management of paediatric bladder and prostate rhabdomyosarcoma. 61
26579243 2013
26
Editorial comment on: The surgical management of paediatric bladder and prostate rhabdomyosarcoma. 61
26579244 2013
27
What is the evidence for radical surgery in the management of localized embryonal bladder/prostate rhabdomyosarcoma? 61
22287287 2012
28
Proton radiotherapy for pediatric bladder/prostate rhabdomyosarcoma: clinical outcomes and dosimetry compared to intensity-modulated radiation therapy. 61
20934266 2011
29
Primary embryonal rhabdomyosarcoma of the prostate in adults: report of a case and review of the literature. 61
21427103 2011
30
Comparison of different adjuvant radiotherapy approaches in childhood bladder/prostate rhabdomyosarcoma treated with conservative surgery. 61
22037652 2011
31
Treatment efficiency, outcome and surgical treatment problems in patients suffering from localized embryonal bladder/prostate rhabdomyosarcoma: a report from the Cooperative Soft Tissue Sarcoma trial CWS-96. 61
21370402 2011
32
Symphysiotomy: a valuable approach in children with prostate rhabdomyosarcoma. 61
19904545 2010
33
Embryonal rhabdomyosarcoma of the prostate. 61
20087615 2010
34
Primary embryonal rhabdomyosarcoma of the prostate in an adult. 61
20135959 2010
35
Mixed embryonal/alveolar rhabdomyosarcoma of the prostate: report of a case with molecular genetic studies and literature review. 61
19175284 2009
36
Embryonal prostatic rhabdomyosarcomas disguised presentation in an adolescent male: a case report. 61
19918470 2009
37
Bilateral pulmonary alveolar infiltrate and prostate tumour in a 54-year-old man. 61
21686581 2009
38
Second cancers in children treated with modern radiotherapy techniques. 61
18707783 2008
39
Colon pouch (Mainz III) for continent urinary diversion. 61
17346278 2007
40
Bladder/prostate rhabdomyosarcoma: past, present and future. 61
16952614 2006
41
Bladder/prostate rhabdomyosarcoma: miles to go before we sleep. 61
16952611 2006
42
Significance of persistent mature rhabdomyoblasts in bladder/prostate rhabdomyosarcoma: Results from IRS IV. 61
17006261 2006
43
Transpubic radical prostatectomy: a novel approach for rhabdomyosarcoma of the prostate in children. 61
16598509 2006
44
Does the less aggressive multimodal approach of treating bladder-prostate rhabdomyosarcoma preserve bladder function? 61
16280839 2005
45
Re: Does bladder preservation (as a surgical principle) lead to retaining bladder function in bladder/prostate rhabdomyosarcoma? Results from Intergroup Rhabdomyosarcoma Study IV. 61
15540797 2004
46
[Prostate rhabdomyosarcoma]. 61
15666531 2004
47
Does bladder preservation (as a surgical principle) lead to retaining bladder function in bladder/prostate rhabdomyosarcoma? Results from intergroup rhabdomyosarcoma study iv. 61
15126860 2004
48
[Embryonic rhabdomyosarcoma of the prostate. Report of a case and review of the literature]. 61
12830614 2003
49
Treatment modalities of bladder/prostate rhabdomyosarcoma: a review. 61
12806368 2003
50
Primary embryonal rhabdomyosarcoma of prostate in adults: diagnosis and management. 61
14577499 2002

Variations for Prostate Rhabdomyosarcoma

Expression for Prostate Rhabdomyosarcoma

Search GEO for disease gene expression data for Prostate Rhabdomyosarcoma.

Pathways for Prostate Rhabdomyosarcoma

Pathways related to Prostate Rhabdomyosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.68 CKMT2 CKMT1A CKM CKB
2
Show member pathways
10.54 CKM CKB
3 10.07 CKM CKB

GO Terms for Prostate Rhabdomyosarcoma

Biological processes related to Prostate Rhabdomyosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 phosphorylation GO:0016310 9.46 CKMT2 CKMT1A CKM CKB
2 muscle contraction GO:0006936 9.26 CKMT2 CALD1
3 creatine metabolic process GO:0006600 9.26 CKMT2 CKMT1A CKM CKB
4 phosphocreatine biosynthetic process GO:0046314 8.92 CKMT2 CKMT1A CKM CKB

Molecular functions related to Prostate Rhabdomyosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transferase activity GO:0016740 9.72 CKMT2 CKMT1A CKM CKB BMT2
2 kinase activity GO:0016301 9.56 CKMT2 CKMT1A CKM CKB
3 catalytic activity GO:0003824 9.46 CKMT2 CKMT1A CKM CKB
4 transferase activity, transferring phosphorus-containing groups GO:0016772 9.26 CKMT2 CKMT1A CKM CKB
5 creatine kinase activity GO:0004111 8.92 CKMT2 CKMT1A CKM CKB

Sources for Prostate Rhabdomyosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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