MCID: PRS044
MIFTS: 26

Prostate Sarcoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Prostate Sarcoma

MalaCards integrated aliases for Prostate Sarcoma:

Name: Prostate Sarcoma 12 15 71
Sarcoma of the Prostate 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4054
NCIt 49 C7731
UMLS 71 C0238393

Summaries for Prostate Sarcoma

Disease Ontology : 12 A prostate cancer that is located in the prostate.

MalaCards based summary : Prostate Sarcoma, also known as sarcoma of the prostate, is related to prostate leiomyosarcoma and prostate stromal sarcoma. An important gene associated with Prostate Sarcoma is FNDC1 (Fibronectin Type III Domain Containing 1), and among its related pathways/superpathways is Arginine and proline metabolism. Affiliated tissues include prostate, myeloid and bone.

Related Diseases for Prostate Sarcoma

Diseases related to Prostate Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 47)
# Related Disease Score Top Affiliating Genes
1 prostate leiomyosarcoma 31.2 SCARA5 PLCB2 KLK3 GPSM3 FNDC1
2 prostate stromal sarcoma 29.1 SCARA5 KLK3 CD34
3 prostate rhabdomyosarcoma 27.7 TMEM168 MIR1915HG CKMT2 CKMT1A
4 kaposi sarcoma 11.4
5 spindle cell sarcoma 10.6
6 sarcoma 10.6
7 leiomyosarcoma 10.3
8 rhabdomyosarcoma 10.2
9 myeloid sarcoma 10.2
10 leukemia, acute myeloid 10.0
11 prostate leiomyoma 10.0 KLK3 CD34
12 myeloid leukemia 9.9
13 ewing sarcoma 9.9
14 rectum cancer 9.9
15 fibrosarcoma 9.9
16 carcinosarcoma 9.9
17 rare tumor 9.9
18 alveolar soft part sarcoma 9.8
19 myelodysplastic syndrome 9.8
20 hydronephrosis 9.8
21 acute kidney failure 9.8
22 urinary tract obstruction 9.8
23 monophasic synovial sarcoma 9.8
24 kidney disease 9.8
25 soft tissue sarcoma 9.8
26 back pain 9.8
27 pelvic lipomatosis 9.8 PRUNE2 CD34
28 bladder cancer 9.8
29 prostate cancer 9.8
30 osteogenic sarcoma 9.8
31 sarcoma, synovial 9.8
32 gastrointestinal stromal tumor 9.8
33 inflammatory myofibroblastic tumor 9.8
34 prostatitis 9.8
35 malignant fibroxanthoma 9.8
36 rectum adenocarcinoma 9.8
37 adenocarcinoma 9.8
38 mesenchymal cell neoplasm 9.8
39 liposarcoma 9.8
40 spindle cell carcinoma 9.8
41 histiocytoma 9.8
42 fibrous histiocytoma 9.8
43 seminoma 9.8
44 malignant peripheral nerve sheath tumor 9.8
45 embryonal sarcoma 9.8
46 undifferentiated pleomorphic sarcoma 9.8
47 dressler's syndrome 9.4 CKMT2 CKMT1A

Graphical network of the top 20 diseases related to Prostate Sarcoma:



Diseases related to Prostate Sarcoma

Symptoms & Phenotypes for Prostate Sarcoma

Drugs & Therapeutics for Prostate Sarcoma

Search Clinical Trials , NIH Clinical Center for Prostate Sarcoma

Genetic Tests for Prostate Sarcoma

Anatomical Context for Prostate Sarcoma

The Foundational Model of Anatomy Ontology organs/tissues related to Prostate Sarcoma:

19
Prostate

MalaCards organs/tissues related to Prostate Sarcoma:

40
Prostate, Myeloid, Bone, Kidney, Bone Marrow, Colon, Liver

Publications for Prostate Sarcoma

Articles related to Prostate Sarcoma:

(show top 50) (show all 141)
# Title Authors PMID Year
1
Unusual endobronchial prostatic metastatic tumor occluding right main bronchus. 61
30674209 2019
2
Stromal sarcoma of the prostate. 61
30797253 2019
3
Complete resection of adult prostatic rhabdomyosarcoma with 3D video and printing model: A case report and literature review. 61
30562915 2019
4
Demographics, stage distribution, and relative roles of surgery and radiotherapy on survival of persons with primary prostate sarcomas. 61
30453392 2018
5
Primary malignant peripheral nerve sheath tumor of prostate in a young adult: A case report. 61
30278486 2018
6
Primary Myeloid Sarcoma of the Prostate: A Case Report and Literature Review. 61
29854498 2018
7
Alveolar soft-part sarcoma of the prostate: a case report and review of the literature. 61
31949591 2018
8
Stereotactic Body Radiotherapy for Spinal Metastases: Clinical Experience in 134 Cases From a Single Japanese Institution. 61
30355246 2018
9
Surgical Management of Primary Spindle Cell Sarcoma of Prostate. 61
28411101 2017
10
Long term follow-up of surgery management of prostate leiomyosarcoma metastasized to the rib: A case report and literature review. 61
27330784 2016
11
Primary prostate sarcoma: how to manage following diagnosis at transurethral resection. 61
27147716 2016
12
Multimodal Therapy in the Treatment of Prostate Sarcoma: The Johns Hopkins Experience. 61
26003268 2015
13
Contrast-enhanced ultrasound aids in the detection of prostate rhabdomyosarcoma: A case report and literature review. 61
26622705 2015
14
Primary spindle cell sarcoma of the prostate and (18)F-fluorodeoxyglucose-positron-emission tomography/computed tomography findings. 61
25657562 2015
15
Is it really an abscess? An unusual case of metastatic stromal cell sarcoma of the prostate. 61
26581082 2015
16
Histologic variability and diverse oncologic outcomes of prostate sarcomas. 61
25512813 2014
17
[Leiomyosarcoma of the prostate treated with neoadjuvant intra-arterial chemotherapy and pelvic excenteration ; a case report]. 61
25511947 2014
18
Prostate sarcoma: report of 2 cases and bibliographic review. 61
25306988 2014
19
Adult prostate sarcoma: the Memorial Sloan Kettering experience. 61
25168544 2014
20
Survey of clinical and pathological characteristics and outcomes of patients with prostate cancer. 61
25363179 2014
21
Two different surgical approaches for prostatic stromal sarcoma: robot-assisted laparoscopic radical prostatectomy and open radical cysto-prostatectomy with ileal conduit. 61
25237465 2014
22
Best practices recommendations in the application of immunohistochemistry in the prostate: report from the International Society of Urologic Pathology consensus conference. 61
25029122 2014
23
[Prostatic stromal tumors of uncertain malignant potential (STUMP): a case report]. 61
24950874 2014
24
Primary synovial sarcoma of the prostate metastatic to the liver and lung: a case report. 61
24969223 2014
25
[A case report of prostate sarcoma with bone marrow metastasis]. 61
24666502 2014
26
High-Grade Primary Spindle Cell Sarcoma of the Prostate: A Case Report and Review of the Literature. 61
29147368 2013
27
Common chromosomal aberrations detected by array comparative genomic hybridization in specialized stromal tumors of the prostate. 61
23765249 2013
28
Twenty-five cases of adult prostate sarcoma treated at a high-volume institution from 1989 to 2009. 61
23601444 2013
29
Ewing's sarcoma/primitive neuroectodermal tumour of the prostate: A case report and literature review. 61
23826070 2013
30
[Prostatic Stromal Tumors of Uncertain Malignant Potential (STUMP): definition, pathology, prognosis and management]. 61
22999114 2012
31
Spindle-cell carcinoma of the prostate. 61
31528563 2012
32
[Adult prostate sarcoma: a clinicopathologic study of 15 cases]. 61
22336158 2011
33
[Undifferentiated prostate sarcoma with cartilage metaplasia: a case report and review of the literature]. 61
22049797 2011
34
Prostatic stromal tumor with fatal outcome in a young man: histopathological and immunohistochemical case presentation. 61
21234249 2010
35
[Granulocytic sarcoma of the prostate]. 61
20940529 2010
36
Primary seminoma of the prostate. 61
20002841 2009
37
Sarcoma of the prostate: a single institutional review. 61
19194120 2009
38
Adult prostate sarcoma: radiological-clinical correlation. 61
19103347 2009
39
Pure primary prostatic osteosarcoma arising in a non-irradiated prostate. 61
19752624 2009
40
Myeloid sarcoma of the prostate revealed by urinary retention: a case report. 61
21686890 2009
41
Coexistence of gastrointestinal stromal tumor (GIST) of the rectum and adenocarcinoma of the prostate in a patient with familial GIST. 61
19060509 2008
42
Primary high grade sarcoma of the specialised prostatic stroma: a case report with clinico-pathological considerations. 61
19475893 2008
43
[Granulocytic sarcoma of the prostate presenting with urinary obstruction which progressed to acute myeloid leukemia]. 61
19047789 2008
44
Prostatic stromal hyperplasia with atypia: follow-up study of 18 cases. 61
18976007 2008
45
Primary synovial sarcoma of the prostate: report of 2 cases and literature review. 61
18387992 2008
46
[Prostatic stromal sarcoma: a case report]. 61
18260357 2008
47
Sarcoma of the prostate: sonographic findings and pathologic correlation. 61
18029933 2007
48
[Adult prostate sarcoma: a report of 6 cases with clinical analysis]. 61
17725305 2007
49
Adult genitourinary sarcoma: the 25-year Memorial Sloan-Kettering experience. 61
17070247 2006
50
Management of a malignant urinary fistula by ureteral embolization with coils. 61
16904469 2006

Variations for Prostate Sarcoma

Expression for Prostate Sarcoma

Search GEO for disease gene expression data for Prostate Sarcoma.

Pathways for Prostate Sarcoma

Pathways related to Prostate Sarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.38 CKMT2 CKMT1A

GO Terms for Prostate Sarcoma

Biological processes related to Prostate Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 creatine metabolic process GO:0006600 8.96 CKMT2 CKMT1A
2 phosphocreatine biosynthetic process GO:0046314 8.62 CKMT2 CKMT1A

Molecular functions related to Prostate Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transferase activity, transferring phosphorus-containing groups GO:0016772 8.96 CKMT2 CKMT1A
2 creatine kinase activity GO:0004111 8.62 CKMT2 CKMT1A

Sources for Prostate Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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