MCID: PRS015
MIFTS: 25

Prostate Signet Ring Cell Adenocarcinoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Prostate Signet Ring Cell Adenocarcinoma

MalaCards integrated aliases for Prostate Signet Ring Cell Adenocarcinoma:

Name: Prostate Signet Ring Cell Adenocarcinoma 12 15
Acinar Prostate Adenocarcinoma, Signet Ring Variant 70
Signet Ring Cell Carcinoma of Prostate 12
Prostate Signet Ring Cell Carcinoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3504
NCIt 50 C5535
UMLS 70 C1335520

Summaries for Prostate Signet Ring Cell Adenocarcinoma

MalaCards based summary : Prostate Signet Ring Cell Adenocarcinoma, also known as acinar prostate adenocarcinoma, signet ring variant, is related to signet ring cell adenocarcinoma and leukemia, chronic lymphocytic. An important gene associated with Prostate Signet Ring Cell Adenocarcinoma is KLK3 (Kallikrein Related Peptidase 3), and among its related pathways/superpathways is Adhesion. Affiliated tissues include prostate.

Related Diseases for Prostate Signet Ring Cell Adenocarcinoma

Graphical network of the top 20 diseases related to Prostate Signet Ring Cell Adenocarcinoma:



Diseases related to Prostate Signet Ring Cell Adenocarcinoma

Symptoms & Phenotypes for Prostate Signet Ring Cell Adenocarcinoma

Drugs & Therapeutics for Prostate Signet Ring Cell Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Prostate Signet Ring Cell Adenocarcinoma

Genetic Tests for Prostate Signet Ring Cell Adenocarcinoma

Anatomical Context for Prostate Signet Ring Cell Adenocarcinoma

MalaCards organs/tissues related to Prostate Signet Ring Cell Adenocarcinoma:

40
Prostate

Publications for Prostate Signet Ring Cell Adenocarcinoma

Articles related to Prostate Signet Ring Cell Adenocarcinoma:

# Title Authors PMID Year
1
Good response of an aggressive rare variant of signet ring cell carcinoma of prostate with hormonal therapy. 61
28275015 2017
2
Secondary signet ring cell carcinoma of prostate. 61
24027389 2012
3
Primary signet ring cell adenocarcinoma of the prostate treated by radical prostatectomy after preoperative androgen deprivation. 61
9354959 1997
4
Signet ring cell carcinoma of prostate. Immunohistochemical and ultrastructural study of a case. 61
2476883 1989

Variations for Prostate Signet Ring Cell Adenocarcinoma

Cosmic variations for Prostate Signet Ring Cell Adenocarcinoma:

9 (show top 50) (show all 7592)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM87273255 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.8849G>A p.R2950H 16:72793833-72793833 12
2 COSM87278310 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.5650G>T p.E1884* 16:72797032-72797032 12
3 COSM102023521 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.598C>T p.R200* 16:72889839-72889839 12
4 COSM102020948 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.791C>A p.S264* 16:72812035-72812035 12
5 COSM102027229 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.2908G>T p.E970* 16:72797032-72797032 12
6 COSM149310968 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.5893C>T p.Q1965* 16:72796789-72796789 12
7 COSM87289963 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.2728G>A p.E910K 16:72950957-72950957 12
8 COSM87277276 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.2986A>T p.K996* 16:72950699-72950699 12
9 COSM102022171 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.6107G>A p.R2036H 16:72793833-72793833 12
10 COSM102025889 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.244A>T p.K82* 16:72950699-72950699 12
11 COSM149331699 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.5114C>G p.S1705* 16:72797568-72797568 12
12 COSM87287233 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.4819C>T p.Q1607* 16:72797863-72797863 12
13 COSM87296500 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.5114C>G p.S1705* 16:72797568-72797568 12
14 COSM149269669 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.3340C>T p.R1114* 16:72889839-72889839 12
15 COSM87271970 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.3533C>A p.S1178* 16:72812035-72812035 12
16 COSM149281678 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.5650G>T p.E1884* 16:72797032-72797032 12
17 COSM149265910 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.8849G>A p.R2950H 16:72793833-72793833 12
18 COSM87274612 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.3340C>T p.R1114* 16:72889839-72889839 12
19 COSM102031608 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.-23-8776C>G p.? 16:72959741-72959741 12
20 COSM149307401 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.4819C>T p.Q1607* 16:72797863-72797863 12
21 COSM87288892 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.5893C>T p.Q1965* 16:72796789-72796789 12
22 COSM149287761 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.6445C>T p.R2149C 16:72796237-72796237 12
23 COSM102037736 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.2077C>T p.Q693* 16:72797863-72797863 12
24 COSM149262752 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.3533C>A p.S1178* 16:72812035-72812035 12
25 COSM87281944 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.405C>G p.Y135* 16:72959741-72959741 12
26 COSM102047721 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.2372C>G p.S791* 16:72797568-72797568 12
27 COSM102029776 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.3703C>T p.R1235C 16:72796237-72796237 12
28 COSM87280241 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.6445C>T p.R2149C 16:72796237-72796237 12
29 COSM149314230 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.2728G>A p.E910K 16:72950957-72950957 12
30 COSM149278210 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.2986A>T p.K996* 16:72950699-72950699 12
31 COSM102039151 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.3151C>T p.Q1051* 16:72796789-72796789 12
32 COSM102040223 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.-15G>A p.? 16:72950957-72950957 12
33 COSM149292073 ZFHX3 prostate,NS,carcinoma,adenocarcinoma c.405C>G p.Y135* 16:72959741-72959741 12
34 COSM89894202 YES1 prostate,NS,carcinoma,adenocarcinoma c.119C>G p.S40* 18:756709-756709 12
35 COSM136834926 YES1 prostate,NS,carcinoma,adenocarcinoma c.590-1G>T p.? 18:745858-745858 12
36 COSM152021810 YES1 prostate,NS,carcinoma,adenocarcinoma c.575-1G>T p.? 18:745858-745858 12
37 COSM152022004 YES1 prostate,NS,carcinoma,adenocarcinoma c.119C>G p.S40* 18:756709-756709 12
38 COSM136836036 YES1 prostate,NS,carcinoma,adenocarcinoma c.134C>G p.S45* 18:756709-756709 12
39 COSM89892790 YES1 prostate,NS,carcinoma,adenocarcinoma c.575-1G>T p.? 18:745858-745858 12
40 COSM104882949 XPO1 prostate,NS,carcinoma,adenocarcinoma c.1259T>C p.M420T 2:61493040-61493040 12
41 COSM104239299 XPO1 prostate,NS,carcinoma,adenocarcinoma c.1384G>T p.V462F 2:61492915-61492915 12
42 COSM101975701 XPO1 prostate,NS,carcinoma,adenocarcinoma c.1711G>A p.E571K 2:61492337-61492337 12
43 COSM101977073 XPO1 prostate,NS,carcinoma,adenocarcinoma c.1259T>C p.M420T 2:61493040-61493040 12
44 COSM101976154 XPO1 prostate,NS,carcinoma,adenocarcinoma c.2468T>G p.F823C 2:61485808-61485808 12
45 COSM104881227 XPO1 prostate,NS,carcinoma,adenocarcinoma c.1711G>A p.E571K 2:61492337-61492337 12
46 COSM104238027 XPO1 prostate,NS,carcinoma,adenocarcinoma c.3101T>G p.F1034C 2:61478935-61478935 12
47 COSM104236414 XPO1 prostate,NS,carcinoma,adenocarcinoma c.1259T>C p.M420T 2:61493040-61493040 12
48 COSM101979599 XPO1 prostate,NS,carcinoma,adenocarcinoma c.1384G>T p.V462F 2:61492915-61492915 12
49 COSM101981883 XPO1 prostate,NS,carcinoma,adenocarcinoma c.1098T>A p.F366L 2:61494041-61494041 12
50 COSM104888806 XPO1 prostate,NS,carcinoma,adenocarcinoma c.1098T>A p.F366L 2:61494041-61494041 12

Expression for Prostate Signet Ring Cell Adenocarcinoma

Search GEO for disease gene expression data for Prostate Signet Ring Cell Adenocarcinoma.

Pathways for Prostate Signet Ring Cell Adenocarcinoma

Pathways related to Prostate Signet Ring Cell Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.71 KLK3 CEACAM5

GO Terms for Prostate Signet Ring Cell Adenocarcinoma

Sources for Prostate Signet Ring Cell Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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