MCID: PRS008
MIFTS: 25

Prostate Small Cell Carcinoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Prostate Small Cell Carcinoma

MalaCards integrated aliases for Prostate Small Cell Carcinoma:

Name: Prostate Small Cell Carcinoma 12 15 17
Small Cell Carcinoma of Prostate 12 71
Prostate Oat Cell Carcinoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:7141
NCIt 50 C6766
SNOMED-CT 67 396198006
UMLS 71 C1300585

Summaries for Prostate Small Cell Carcinoma

MalaCards based summary : Prostate Small Cell Carcinoma, also known as small cell carcinoma of prostate, is related to small cell carcinoma and suppression of tumorigenicity 12. An important gene associated with Prostate Small Cell Carcinoma is BRCA2 (BRCA2 DNA Repair Associated), and among its related pathways/superpathways is Coregulation of Androgen receptor activity. Affiliated tissues include prostate.

Related Diseases for Prostate Small Cell Carcinoma

Graphical network of the top 20 diseases related to Prostate Small Cell Carcinoma:



Diseases related to Prostate Small Cell Carcinoma

Symptoms & Phenotypes for Prostate Small Cell Carcinoma

Drugs & Therapeutics for Prostate Small Cell Carcinoma

Search Clinical Trials , NIH Clinical Center for Prostate Small Cell Carcinoma

Genetic Tests for Prostate Small Cell Carcinoma

Anatomical Context for Prostate Small Cell Carcinoma

MalaCards organs/tissues related to Prostate Small Cell Carcinoma:

40
Prostate

Publications for Prostate Small Cell Carcinoma

Articles related to Prostate Small Cell Carcinoma:

(show all 30)
# Title Authors PMID Year
1
Effective treatment of relapsed prostate small cell carcinoma with amrubicin: report of a case. 61
32582522 2020
2
Current trend of worsening prognosis of prostate small cell carcinoma: A population-based study. 61
31518071 2019
3
Molecular analysis and literature-based hypothesis of an immunonegative prostate small cell carcinoma causing ectopic ACTH syndrome. 61
30918166 2019
4
Small Cell Transformation of Metastatic Prostate Adenocarcinoma Diagnosed by Dual-Tracer PET/CT (68Ga-PSMA and 18F-FDG): Potential Clinical Utility in Therapeutic Decision Making and Treatment Monitoring. 61
30139889 2019
5
Pure Small Cell Carcinoma of Prostate: A Report of 8 Cases. 61
30269133 2018
6
Small Cell Carcinoma of Prostate: A Case Report of a Patient With Concomitant Transitional Cell Cancer of the Bladder. 61
29536021 2018
7
Function of Tumor Suppressors in Resistance to Antiandrogen Therapy and Luminal Epithelial Plasticity of Aggressive Variant Neuroendocrine Prostate Cancers. 61
29600194 2018
8
[Etoposide and Carboplatin Effective for Treatment of Small Cell Carcinoma of Prostate : A Report of Two Cases]. 61
28103658 2016
9
Emerging trends in the evaluation and management of small cell prostate cancer: a clinical and molecular perspective. 61
27534689 2016
10
Primary small cell carcinoma of prostate without immunoreactive neuroendocrine proteins but with expressions of KIT and platelet-derived growth factor-α. 61
25195713 2015
11
Genitourinary small cell malignancies: prostate and bladder. 61
25675127 2015
12
Clinicopathological study of prostatic biopsies. 61
25386437 2014
13
Current approaches for prophylactic cranial irradiation in extrapulmonary small cell carcinoma. 61
24628530 2014
14
Small cell carcinoma of the urinary bladder and prostate: Cytological analyses of four cases with emphasis on the usefulness of cytological examination. 61
24396449 2014
15
Clinical impact of 18F-fluorodeoxyglucose positron emission tomography/computed tomography in the evaluation of small cell carcinoma of the prostate. 61
23218515 2013
16
Small cell carcinoma of the prostate. A morphologic and immunohistochemical study of 95 cases. 61
18162772 2008
17
Prostate small cell carcinoma and skin metastases: a rare entity. 61
18408396 2008
18
Submandibular area metastasis from prostate small cell carcinoma with neuroendocrine differentiation. 61
17912103 2007
19
Extrapulmonary small cell carcinoma of the bladder. 61
17270661 2007
20
[Prostate small cell carcinoma: report of two cases that differed in treatment responsiveness]. 61
17176877 2006
21
[Small cell carcinoma of the prostate: an autopsy case report]. 61
16050480 2005
22
Metastatic pure small-cell carcinoma of prostate. 61
15545846 2004
23
Molecular characterization of prostatic small-cell neuroendocrine carcinoma. 61
12640661 2003
24
Brain metastasis from prostate small cell carcinoma: not to be neglected. 61
12463494 2002
25
[Small cell (oat cell) carcinoma of the prostate. Presentation of a case and review of the literature]. 61
1324565 1992
26
Small cell carcinoma of prostate: effectiveness of hormonal versus chemotherapy. 61
1315995 1992
27
Small-cell carcinoma of prostate. 61
2538948 1989
28
Small cell carcinoma of prostate associated with myasthenic (Eaton-Lambert) syndrome. 61
2536972 1989
29
Small cell carcinoma of prostate. 61
2536204 1989
30
Small-cell carcinoma of prostate. Transient complete remission with chemotherapy. 61
2992147 1985

Variations for Prostate Small Cell Carcinoma

Cosmic variations for Prostate Small Cell Carcinoma:

9 (show top 50) (show all 308)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM102039111 ZFHX3 prostate,NS,carcinoma,small cell carcinoma c.-23-8472C>T p.? 16:72959437-72959437 9
2 COSM87288852 ZFHX3 prostate,NS,carcinoma,small cell carcinoma c.709C>T p.R237* 16:72959437-72959437 9
3 COSM149310929 ZFHX3 prostate,NS,carcinoma,small cell carcinoma c.709C>T p.R237* 16:72959437-72959437 9
4 COSM85232645 YAP1 prostate,NS,carcinoma,small cell carcinoma c.1114C>T p.Q372* 11:102223703-102223703 9
5 COSM126968980 YAP1 prostate,NS,carcinoma,small cell carcinoma c.580C>T p.Q194* 11:102223703-102223703 9
6 COSM145023934 YAP1 prostate,NS,carcinoma,small cell carcinoma c.964C>T p.Q322* 11:102223703-102223703 9
7 COSM133268543 YAP1 prostate,NS,carcinoma,small cell carcinoma c.1078C>T p.Q360* 11:102223703-102223703 9
8 COSM143037036 YAP1 prostate,NS,carcinoma,small cell carcinoma c.1126C>T p.Q376* 11:102223703-102223703 9
9 COSM127994003 YAP1 prostate,NS,carcinoma,small cell carcinoma c.1066C>T p.Q356* 11:102223703-102223703 9
10 COSM128447630 YAP1 prostate,NS,carcinoma,small cell carcinoma c.952C>T p.Q318* 11:102223703-102223703 9
11 COSM90943480 YAP1 prostate,NS,carcinoma,small cell carcinoma c.1012C>T p.Q338* 11:102223703-102223703 9
12 COSM149729738 WT1 prostate,NS,carcinoma,small cell carcinoma c.526C>G p.R176G 11:32434820-32434820 9
13 COSM111530770 WT1 prostate,NS,carcinoma,small cell carcinoma c.544C>T p.P182S 11:32434802-32434802 9
14 COSM148583114 WT1 prostate,NS,carcinoma,small cell carcinoma c.526C>G p.R176G 11:32434820-32434820 9
15 COSM147416459 WT1 prostate,NS,carcinoma,small cell carcinoma c.544C>T p.P182S 11:32434802-32434802 9
16 COSM91374081 WT1 prostate,NS,carcinoma,small cell carcinoma c.526C>G p.R176G 11:32434820-32434820 9
17 COSM91374068 WT1 prostate,NS,carcinoma,small cell carcinoma c.544C>T p.P182S 11:32434802-32434802 9
18 COSM111530781 WT1 prostate,NS,carcinoma,small cell carcinoma c.526C>G p.R176G 11:32434820-32434820 9
19 COSM148583099 WT1 prostate,NS,carcinoma,small cell carcinoma c.544C>T p.P182S 11:32434802-32434802 9
20 COSM147416467 WT1 prostate,NS,carcinoma,small cell carcinoma c.526C>G p.R176G 11:32434820-32434820 9
21 COSM149729735 WT1 prostate,NS,carcinoma,small cell carcinoma c.544C>T p.P182S 11:32434802-32434802 9
22 COSM113476939 WT1 prostate,NS,carcinoma,small cell carcinoma c.526C>G p.R176G 11:32434820-32434820 9
23 COSM113476928 WT1 prostate,NS,carcinoma,small cell carcinoma c.544C>T p.P182S 11:32434802-32434802 9
24 COSM122828715 TP53 prostate,NS,carcinoma,small cell carcinoma c.321C>G p.N107K 17:7674246-7674246 9
25 COSM145017326 TP53 prostate,NS,carcinoma,small cell carcinoma c.407G>A p.R136H 17:7675088-7675088 9
26 COSM143166602 TP53 prostate,NS,carcinoma,small cell carcinoma c.196-2A>C p.? 17:7674292-7674292 9
27 COSM144162622 TP53 prostate,NS,carcinoma,small cell carcinoma c.240C>G p.N80K 17:7674246-7674246 9
28 COSM122271291 TP53 prostate,NS,carcinoma,small cell carcinoma c.128G>A p.R43H 17:7675088-7675088 9
29 COSM87912114 TP53 prostate,NS,carcinoma,small cell carcinoma c.673-2A>C p.? 17:7674292-7674292 9
30 COSM105632468 TP53 prostate,NS,carcinoma,small cell carcinoma c.673-2A>C p.? 17:7674292-7674292 9
31 COSM106064934 TP53 prostate,NS,carcinoma,small cell carcinoma c.673-2A>C p.? 17:7674292-7674292 9
32 COSM144096306 TP53 prostate,NS,carcinoma,small cell carcinoma c.196-2A>C p.? 17:7674292-7674292 9
33 COSM143943797 TP53 prostate,NS,carcinoma,small cell carcinoma c.266G>A p.R89Q 17:7674220-7674220 9
34 COSM144385433 TP53 prostate,NS,carcinoma,small cell carcinoma c.600C>G p.N200K 17:7674246-7674246 9
35 COSM142846093 TP53 prostate,NS,carcinoma,small cell carcinoma c.673-2A>C p.? 17:7674292-7674292 9
36 COSM121889406 TP53 prostate,NS,carcinoma,small cell carcinoma c.277-2A>C p.? 17:7674292-7674292 9
37 COSM122733880 TP53 prostate,NS,carcinoma,small cell carcinoma c.128G>A p.R43H 17:7675088-7675088 9
38 COSM144087106 TP53 prostate,NS,carcinoma,small cell carcinoma c.266G>A p.R89Q 17:7674220-7674220 9
39 COSM145029266 TP53 prostate,NS,carcinoma,small cell carcinoma c.556-2A>C p.? 17:7674292-7674292 9
40 COSM112253686 TP53 prostate,NS,carcinoma,small cell carcinoma c.536A>G p.H179R 17:7675076-7675076 9
41 COSM112253622 TP53 prostate,NS,carcinoma,small cell carcinoma c.743G>A p.R248Q 17:7674220-7674220 9
42 COSM87897745 TP53 prostate,NS,carcinoma,small cell carcinoma c.524G>A p.R175H 17:7675088-7675088 9
43 COSM106053255 TP53 prostate,NS,carcinoma,small cell carcinoma c.536A>G p.H179R 17:7675076-7675076 9
44 COSM88004535 TP53 prostate,NS,carcinoma,small cell carcinoma c.717C>G p.N239K 17:7674246-7674246 9
45 COSM143157023 TP53 prostate,NS,carcinoma,small cell carcinoma c.367C>T p.R123W 17:7673776-7673776 9
46 COSM144310203 TP53 prostate,NS,carcinoma,small cell carcinoma c.626G>A p.R209Q 17:7674220-7674220 9
47 COSM144024351 TP53 prostate,NS,carcinoma,small cell carcinoma c.640-2A>C p.? 17:7674292-7674292 9
48 COSM111758876 TP53 prostate,NS,carcinoma,small cell carcinoma c.844C>T p.R282W 17:7673776-7673776 9
49 COSM122271559 TP53 prostate,NS,carcinoma,small cell carcinoma c.347G>A p.R116Q 17:7674220-7674220 9
50 COSM121971380 TP53 prostate,NS,carcinoma,small cell carcinoma c.321C>G p.N107K 17:7674246-7674246 9

Expression for Prostate Small Cell Carcinoma

Search GEO for disease gene expression data for Prostate Small Cell Carcinoma.

Pathways for Prostate Small Cell Carcinoma

Pathways related to Prostate Small Cell Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.38 TMPRSS2 KDM4C

GO Terms for Prostate Small Cell Carcinoma

Sources for Prostate Small Cell Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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